Chaw ei hi a harsa em? Eosinophilic Esophagitis (EoE) a ni thei ang em?

Chaw i ei lai hian chaw ei harsa i ti em, a nih loh leh i kawr chhungah a inkhung ang maiin i inhria em? Nge i rilruah kang emaw, na emaw i nei em? Mi tam tak chuan hei hi gastritis niin an ngai a, mahse a chang chuan hei hi a chhan chu thil danglam tak, allergy nena inzawm a ni thei. Hetiang dinhmun avang hian mi thenkhat phei chuan ei duh lo ang maiin an inhria. Vawiin hian hetiang dinhmun hi kan sawi dawn a, mahse mi tam takin an hre lo, Eosinophilic Esophagitis an tih chu.

A awlsam zawngin sawi ila, Eosinophilic Esophagitis (EoE) hi eng nge ni?

He hming hi a buaithlak deuhin a lang thei a, mahse a thawnthu hi a awlsam hle. He hming hi i ṭhen darh ang u.

• Esophagus hi kan ka atanga kan pum thlenga ei tur phurtu tube a ni. Hei hi Sinhala tawngin gullet kan ti thin.
• Eosinophils hi kan taksaa thisen var chi khat a ni. Allergy kan neih hian kan taksaah an pung tlangpui.
• Suffix -itis tih awmzia chu "inflammation" emaw "swelling" emaw tihna a ni.

A awlsam zawngin sawi ila, Eosinophilic Esophagitis (EoE) hi allergic reaction a ni a, kan chaw kawng chhungah thisen var eosinophils an tih chu a lo awm khawm a, chu chuan chaw kawng a ti na a ni. Eczema ang maiin han ngaihtuah teh, vun chu a sen a, a hring a, a hnim a, mahse chutiang bawk chu chaw kawng chhungah a thleng thin.

Hetianga a hring chhunzawm zel chuan esophagus chhungah hian scar tissue a lo awm a, ei tur kalna tur kawng chu a ti tawi a ni. Hei hi i ei harsat tan leh i ei tur chu a tlakbuak ang maia i hriat hun a ni. I chaw ei chu i ka atanga i pum thlengin awlsam takin a kal lo mai thei a, a tang tih a hriat theih bawk. Hei hi natna khirh tak a ni. Chumi awmzia chu zan khat thil thuah a dam leh dawn lo tihna a ni a, i dam chhung zawngin inenkawlna i lak a ngai dawn tihna a ni. Mahse lungngai suh, a thunun thei tur enkawlna tha tak tak a awm.

EoE natna lan chhuah dan chu engte nge ni? Kum upat dan azirin an inthlak danglam em?

Ni e, he natna lan chhuah dan hi kum a zirin a danglam thei. Nausen tê têa a lan chhuah dân a ni lo va, puitlingah a lan chhuah dân a ni. Hei hi chiang taka kan hriatthiam theih nan hei hi han thlir ila.

Heng symptom lian ber berte bakah hian kum eng pawha lo lang thei symptom dang engemaw zat a awm a:

• Pum na: Pum na hmun a na.
• Nausea leh vomiting: Chaw ei zawha nausea leh luak chhuak.
• Regurgitation: Chaw ei tawh chu rilru emaw ka chhungah emaw a rawn kir leh thin.
• Food Impaction: Hei hi damdawi lam emergency a ni . Chaw ei tur chi khat chu chaw kawng (esophagus) hmun zau takah a tang a, a rilruah a tla thla lo va, a rawn chho leh lo bawk. Chutiang hunah chuan chaw kawng (esophageal rupture) hlauhawmna a awm a, chuvangin damdawi in emergency room (ETU) pan nghal a pawimawh hle.

Engvangin nge hetiang hi kan neih? Eng nge a chhan?

A awlsam zawngin, hei hi a chhan ber chu kan immune system hian allergens thenkhat a overreact vang a ni. A dik tak chuan kan eitur chhunga thil thenkhat, emaw, kan chhehvela thil awm, leivut ang chi te chu kan thawkna kawngah a luh hian kan taksa chuan hei hi hmêlma lian tak niin a ngai a ni.

Tichuan, immune system chuan ‘hmelma’ bei turin eosinophils telin cell tam tak chu chaw kawng chhungah a thawn lut a ni. Heng cell te hi an pungkhawm a, chaw kawng chhungah inflammation, a nih loh leh swelling an siam thin.

EoE tichhuak thei ei tur pawimawh ber ber

A tam zawkah chuan heng allergy te hi kan ei leh in atanga lo chhuak a ni. Chung zingah chuan rinhlelh lian ber tlemte an awm.

Mi tam zawk chuan heng harsatna zawng zawng hi an nei vek lo. Chûng zînga pakhat emaw, pahnih emaw chu i harsatna thlentu a ni thei mai thei. Enkawlna chungchang kan sawi hunah chiang taka hriat theih dan tur kan la hmu ang.

Tute nge EoE vei theihna chance sang zawk?

He natna hi tu pawhin vei thei mah se, mi thenkhat chuan an vei nasa zawk. A bik takin allergic natna dang nei te chu EoE vei an tam zawk.

• Asthma natna a ni
• Allergic rhinitis - hnar chhuak fo, thawk hah
• Vun natna (Eczema, Atopic dermatitis) .
• Ei leh in allergy dangte

Heng dinhmunte hi i neih hian i taksa hriselna (immune system) chu a tlangpuiin allergens lakah a sensitive zawk tihna a ni. Tin, i chhungkuaa mi pakhatin (nu leh pa, unau) EoE a neih chuan nang pawhin i vei theihna tur risk tlemte i nei bawk.

Engtin nge he natna hi i vei tih chiang taka i hriat theih ang?

A hmaa kan sawi tawh ang khan symptoms i nei a nih chuan i tih hmasak ber tur chu doctor thiam tak i pan a ni. Doctor chuan zawhna tlem a zawt hmasa ang che a, i medical history a en ang.

I doctor i zawh theih thilte:

• I ei dan: I chaw ei chu a ei awlsam zawk nan i ei tha em? Chaw thenkhat, chhang leh sa te hi i pumpelh em? I chaw ei tur i ei theih nan tui i in tam em? Heng thilte hian i doctor hnenah i hriat lohvin i natna lan chhuah dan i hmachhawn dan tur ngaihtuahna a pe thei a ni.
• I damdawi lam dinhmun dangte: Asthma, dust allergy, emaw vun natna i neih leh neih loh zawt rawh.
• I chhungkaw damdawi lam chanchin: I chhungte zingah hian ei leh in lama harsatna ang chi emaw, EoE emaw nei an awm em tih zawt rawh.

He thu a\ang hian i doctor-in EoE a rinhlelh chuan gastroenterologist hnenah a refer ang che a, ani chuan test lian pahnih a nei ang a, chu chuan i natna chu a nemnghet ang.

1. Endoscopy emaw EGD emaw hmangin:Hei hian i kâ hmangin i chaw kawng, i pum, leh i rilru natna (small intestine) a hmasa ber enfiah nân tube te tak te, a tâwp berah camera dahna a huam a ni. Hetiang tih chhung hian natna nei lo damdawi pek i ni ang. Doctor chuan camera kaltlangin i chaw kawng chhunga a hring, a var, leh a zim ang chi thil a hmu thei a ni.

2. Biopsy: Endoscopy an tih lai hian doctor chuan chaw kawng (esophagus) lining atanga tissue sample te tak te a la a. Hei hi biopsy an ti a. Chumi hnuah chuan tissue chu microscope hmangin an enfiah a, eosinophils a tam lutuk em tih an enfiah a ni. He biopsy hi EoE finfiah nan a pawimawh hle.

EoE enkawlna tur hi engte nge ni?

EoE enkawlna tum ber chu chaw kawng chhunga inflammation control hi a ni. Chutianga tih theih dan tlangpui pahnih a awm a, chungte chu damdawi leh ei leh in thlak danglamna te an ni. Nang leh i doctor chuan eng method nge i tana tha ber tih chu in rel dun ang.

Damdawi hmanga enkawl

Heng damdawi te hian ril a hring (swelling) tihziaawmna atan a pui thin.

• Proton Pump Inhibitors (PPIs): Hengte hi gastritis damdawi chi khat, gastritis natna atana an pek tlangpui a ni. EoE vei thenkhatah pawh esophagus-a swelling tihziaawmna turin an pui thei bawk.
• Corticosteroids: Hei hi damdawi chak tak, inflammation tihziaawmna tur a ni. A tlangpuiin topical solution (spray emaw tablet emaw angin) an pe thin. Heng damdawi te hian kawr chhungah direct-in hna an thawk a, chuvangin side effect an nei tlem zawk.
• Biologic agents: Mi thenkhat tan chuan enkawlna dangin hna a thawh loh chuan damdawi bik, dupilumab (Dupixent®) te chu injection angin an pe thin. Hengte hian allergic reaction thlentu immune system hmun bik chu an target a, an control bawk.

Ei leh in thlak danglam (Food Group Elimination) .

Hei pawh hi enkawlna tha tak a ni. A hmaa kan sawi tawh food group lian 6, allergy thlentu tam ber (milk, egg, wheat, soy, nuts, seafood) te chu i ei leh in atanga paih vek a ngai a ni.

1. A hmasa berin heng food group zawng zawng hi rei lo te ei kha bansan rawh.

2. Chumi hnuah chuan Doctor chuan endoscopy leh biopsy a ti leh ang a, chaw kawng a natna chu a tlahniam em tih a en ang.

3. Bloating a tlahniam a nih chuan heng chaw zinga pakhat emaw a aia tam emaw chu i harsatna thlentu a ni tihna a ni.

4. A dawtah chuan ei tur chi hrang hrang tihbo tawhte chu i ei leh inah dah leh la, pakhat hnu pakhatin, kar engemaw zat chhungin dah leh rawh.

5. Food group tin an dah belh hnuah biopsy an ti leh a, a hring chu a lo let leh tawh em tih an enfiah leh thin.

Hetiang hmanraw hi hun rei tak leh buaithlak deuh angin lang mah se, eng ei tur nge i allergy tih chiang taka hriat theihna kawng tha ber a ni. Chu chu i hriat chian hnuah chuan chutiang ei tur chauh chu i pumpelh thei a, thil dang zawng zawng chu a pangngaiin i ei thei bawk.

EoE nena nun hi thil harsa tak a ni em?

EoE hi nunna atana hlauhawm a ni lo a, mahse a rei tawh avangin dam chhung enkawl emaw, ei leh in lama enkawl emaw a ngai a ni.

Mi tam tak tan chuan enkawlna an tan hnuah symptoms chu a bo vek tawh mai. Mahse, mi thenkhat, a bik takin food impaction lama thil tha lo tawk tawhte chuan ei leh in hlauhna (phagophobia) an nei thei a ni. Chhang ang chi chaw lian tak tak ei chu an hlauthawng a, an lungkham hle thei bawk.

Hetiang hunah hian i tanpui thei tur thil tlemte a awm a:

• Midangte nena inzawmna siam: He natna hre chiang leh vei mi dangte nena inbiakna neih hi a \angkai hle thei a ni. Nangmah chauh ni lo ang maiin i inhriat theih nan a pui ang che. I doctor hnenah support group chungchang i zawt thei ang.
• Nutritionist hnen atangin tanpuina la rawh: Nutritionist chuan i tana tha tur leh thil tha lo awm lo ei tur hmangin chaw tui tak siam turin a pui thei che a ni.
• Mental health support la rawh: Chaw ei hlauhna ang chi thil hian i nun a nghawng a nih chuan mental health professional nen inbiakna neih a pawimawh hle.

Enkawlna i neih hnua i natna lan chhuah dan a lo lang leh a nih chuan, emaw, ei harsatna thar i neih chuan doctor pan nghal tur a ni.