I nausen piang lai thisen chi hi i thisen nen a inmil lo em ni? (Erythroblastosis Fetalis) Hei hi eng nge a nih chiang takin i zawng chhuak ang u!

Nu ni tur i nih chuan ‘Erythroblastosis Fetalis’ tih thumal i hriat khan i hlau deuh mai thei. A nih loh leh i doctor hian rei vak lo kalta khan i thisen chi a sawi lai khan a sawi a ni mai thei. He hming hi hriat hi a hlauhawm deuh thei. Mahse lungngai suh, vawiinah hian i hriatthiam theih tur awlsam takin kan sawi dawn a ni. Eng nge a nih, engvangin nge a lo awm a, engtin nge he dinhmun lakah hian kan inven theih ang tih i lo en ang u.

‘Erythroblastosis Fetalis’ tih hi eng nge ni?

A awlsam zawngin sawi ila, hei hi a tlem hle a, mi zawng zawngin an vei lo tihna a ni a, naupai laia lo awm thei complication a ni. Hei hi i naute piang lai nen hian thisen chi hrang hrang inrem lohna a awm chuan a thleng thin. Thisen chi hrang hrang hian harsatna a thlen vek lo. Mahse, he hlauhawmna hi a bik takin i thisen chi hrang hrang Rh-negative leh i naute thisen chi hrang hrang Rh-positive a nih chuan a sang hle.

Ngaihtuah teh, he Rh-positive thisen hi, naupai hmasa emaw, thisen pek lai emaw khan i tawk a nih chuan, i taksa immune system (natna laka min humhimtu system) chuan naute thisen sen (red blood cells) chu a rawn bei tan thei a ni. Hmelma beih ang maiin. Hei hian naute thisen sen (red blood cells) chu hlauhawm takin a ti hniam thei a ni. Hei hi thisen tlakchhamna (anemia) kan ti a. He thisen tlakchhamna hi a nasat chuan enkawl loh chuan naute tan nunna atana hlauhawm tak a ni thei.

Mahse, chanchin lawmawm a awm! Tunlai hian naupai tirh lamah routine test hmangin i thisen chi hrang hrang a hriat theih. Rh-negative i nih chuan doctor ten he harsatna hi ven nan damdawi an pe thei che a ni.

Hetiang dinhmun hi (nausen piang tharte alloimmune hemolytic disease - HDN) leh (nausen leh nausen piang tharte hemolytic disease - HFDN) an ti bawk. Mahse kan sawi dawn chuan (Erythroblastosis Fetalis) tih hi kan hmang dawn a ni.

Naute hian hetiang natna hi a neih chuan eng symptoms nge a neih?

Hetiang natna (Erythroblastosis Fetalis) nei naute piangte hian thisen tlakchhamna chhinchhiahna an nei thei a ni. Nausen thenkhat chuan na lo takin an nei thei a, thenkhat erawh chuan na takin an nei thei thung. Tin, naute hian a pian atanga darkar 24 chhungin jaundice a nei thei bawk. A lan chhuah dan thenkhat chu hetiang hi a ni:

• Mit leh vun a sen (yellowing) thin.
• Vun a rawn sen nghal zung zung.
• Naute chu a lethargic hle a, nunna nei lo (lethargy) a ni.
• Thinlung chu a thawk chak hle (tachycardia).
• Duhthusamin bawnghnute ei duh lohna.

Nausen na tak thenkhatah chuan nausen emaw nausen piang thar emaw hian nunna atana hlauhawm tak hydrops fetalis'' an tih chu a nei thei a ni.A natna lan chhuah dan chu:

• Taksa a hring chhuak.
• Naute pum chhungah emaw, taksa peng pawimawh tak tak, thinlung leh lungte inkarah emaw tui awmkhawm.

Engvangin nge hetiang hi a lo awm? A chhan engte nge ni?

Hetiang dinhmun, Erythroblastosis Fetalis'' tia koh hi a lo awm chhan chu, a hmaa kan sawi tawh ang khan i taksa immune system hian naute thisen sen (red blood cells) a bei vang a ni.

Kan thisen sen (red blood cells) te hian marker bik an nei a. Antigens'' kan ti a, heng antigens'' te hi hming ziakna label angin ngaihtuah rawh. I immune system hian he label hi a hriat chuan chu thisen sen te chu a bei dawn lo.

Hei hi nang leh i naute thisen inthlauhna vang a ni. Thisen chi hrang hrang hi thisen sen chunglama antigens awm dan atanga thliar hran a ni. Thisen chi hrang hrang kan sawi tum ber pahnih a awm a, chungte chu:

• Rh factor: Hei hian thisen chu positive (+) nge negative (-) tihna a ni.
• ABO antigens: Hei hian thisen chi A, B, AB, O tihna a ni.

Naupai i nih chuan i immune system, i naute thisen sen chunga antigens awmte a hriat loh chuan anmahni dotu antigens a siam tan ang. Heng antibodies te hi chu thisen sen (red blood cells) te beitu an ni. Kan taksain natna thlentu hrik a neih ang chiah hian kan taksain a do thin. Mahse hei hi a lo thlen theih nan chuan naute thisen chu i thisen nen a inzawm a ngai a ni. A tam zawkah chuan hetiang hi naute pian dawn lai a thleng thin. Mahse, a chang chuan thisen chu a inhmeh hmain a inhmeh thei. Entir nan:

• Nau pai a nih chuan.
• Naupai lai a chanve vel a bo chuan Miscarriage an ti thin.
• Ectopic pregnancy ang dinhmunah (naupai chu nausen pum pawnah a awm a, fallopian tube-ah ang chi a ni).
• (Amniocentesis) (naupai laiin test tih) tih hunah.
• (Chorionic villus sampling) (naupai test dang) tih hunah.

I taksain heng (antibodies) te hi a siam chhuah tawh chuan a hre reng thin. Nausen thisen sen (red blood cells) te hian chu (antigen) chu a naupai leh hunah an neih leh chuan heng (antibody) te hian chu cell te chu an kal a, an tichhia ang. Hei hi thisen sen tihchhiatna hi (hemolysis) kan ti a.

A chhan ber: Rh inmil lohna

Hetiang natna thlentu na ber leh hriat lar ber chu Rh-negative i nih lai leh i naute Rh-positive a nih hian a ni. Chutiang a nih chuan i immune system chuan i naute Rh-positive red blood cells chu a bei thin. America ang ramah chuan mi 15% velin Rh-negative thisen an nei a. A tam zawkah chuan nu leh pa bakah naute pawh Rh-positive an ni.

A tlangpuiin he Rh incompatibility hian naupai hmasa berah harsatna lian tham a thlen lo. Rh-negative i nih a, naute chu Rh-positive ni mahse, naupai laiin i thisen chu naute thisen nen a inhmeh a, chu chuan reaction na tak (antibodies) a thlen thin. Mahse, naute a lo pian veleh i thisen hian naute thisen nen a inrem ngei ang. Chutih lai chuan i immune system-in a beih loh nan damdawi i ei loh chuan i taksain Rh-positive red blood cells laka antibody a siam thei a ni.

Tichuan i naupai leh a, chu naute pawhin Rh-positive blood type a neih chuan, chu antibodies siam hmasak tawhte chuan chu naute thisen sen (red blood cells) chu a kal ang. I hrethiam em?

Thisen chi hrang hrang inmil lohna hmuh tur awm lo dang

A châng chuan, i immune system hian i naute thisen sen (red blood cells) chu a bei thei a, chu chu thisen sen antigen hmuh tur awm lo tak nen a inmil lo hle a ni. Hei hi i naute hian chu antigen hmuh tur awm lo tak chu a neih a, i hloh chuan a thleng thin. Hei hi naupai hmasa emaw thisen pek emaw hmanga chu antigen i tawk tawh a, chu antibody i siam chhuah chuan a thleng thin. Chung antigen thenkhat chu:

• (Colton)
• (Duffy)
• (Diego) tih a ni
• (Ee) tih a ni
• (Gerbich) tih a ni
• (H) tih a ni
• (Kell) tih a ni
• (Naupang)
• (Lutheran)
• (MNS) tih a ni
• (P) tih a ni
• (Xg) tih a ni

Naupai tirh lama thisen test hian heng thisen sen chi hrang hrang hmuh tur awm lo tak takte laka antibody i siam leh siam loh a hriat theih.

Hetiang dinhmun hi engtiang chiahin nge a awm?

Khawvel pumah nau piang nung 100,000 zinga 276 vel chu Rh thisen chi inrem lohna nena inzawm naupai harsatna an nei nia sawi a ni. Zirchiangtute sawi dan chuan enkawl loh a nih chuan nausen piang lai chu a thih emaw, hriselna lama harsatna lian tak a neih emaw theihna chance 50% a awm a ni.

Mahse, lungngai suh! Thisen chi test leh damdawi mamawh te hmangin a rah chhuah chhe ber pawh a veng thei a ni. Khawvel hmun thenkhatah chuan nau neih hmaa enkawlna hmun thenkhatah chuan nau piang 100,000 zinga 2.5 vel chauhvin Rh incompatibility vangin harsatna an nei a ni. Hei hi Sri Lanka-ah pawh ngaihtuahawm tak a ni.

Engtin nge hei hi i hmuh?

A tlangpuiin antenatal clinic-ah chuan i thisen chi leh antibodies'' eng pawh enfiah thin a ni. Naupai i nih a, Rh-negative blood type i neih chuan i doctor chuan Rh-positive thisen laka antibodies'' a awm leh awm loh a enfiah ang. Chutiang antibodies'' te chu i neih loh chuan i immune system chu an siam chhuah loh nan damdawi pek an ni ang.

Test-in heng antibody te hi i nei tih a finfiah chuan naute chu Rh-positive a nih chuan i immune system hian naute thisen sen (red blood cells) a bei thei tihna a ni. Chumi hnuah chuan i doctor chuan kar engemaw zat danah i antibody level a enfiah ang. I antibody level hlauhawm taka a san chuan i naute hian thisen tlakchhamna a nei em tih hriat nan test dang tih belh a ni thei a, nausen pum chhungah thisen pek a ngai mai thei bawk. I naute chu thisen tlakchhamna nasa tak neia piang hlauhawm a nih chuan i doctor chuan naute chu a hmaa nau neih a rel mai thei.

Naute a pian hnuah doctor chuan naute thisen chi hrang hrang a hre thei a. Hei hian naute thisen tlakchhamna hi thisen chi hrang hrang inrem lohna vang a ni em tih hriat nan a pui thei a ni.

Test dang tih te chu:

• Complete Blood Count (CBC): He test hian naute thisen sen (red blood cells) a hniam zia a enfiah thei a ni. Level a hniam poh leh thisen tlakchhamna a na zual thin.
• Peripheral Blood Smear (PBS): Hei hian thisen sample chu microscope hmanga enfiah a ni. Hei hian a tlahniam chhan chu thisen sen (red blood cells) a hun hmaa tihchhiat vang nge ni tih ngaihtuahna a pe thei a ni.
• Bilirubin test: 1.1.Hei hian bilirubin level a teh a ni. Bilirubin hi thisen sen (red blood cells) tihchhiatna atanga lo chhuak a ni. Bilirubin level sang (hyperbilirubinemia) hian thisen sen (red blood cells) a tichhia tih a tilang thei.
• Direct Antiglobulin Test (DAT): He test hian naute thisen sen (red blood cells) chung lamah antibody a awm leh awm loh a entir a. Chumi awmzia chu nu in immune system hian naute cell a bei tihna a ni.

Enkawlnate chu engte nge ni?

Enkawlna chu naupai emaw, nau neih thar emaw a innghat a ni.

Naupai laia enkawl dan

Erythroblastosis Fetalis vei theihna tur antibody i neih chuan i doctor chuan kar tlemte danah i antibody level a enfiah ang. I antibody level a san chuan i naute chu thisen tlakchham a nih leh nih loh hriat nan ultrasound scan dang i neih belh a ngai mai thei. Thisen tlakchhamna a nasat chuan i naute hian thisen pek a ngai mai thei.

Naute pian hnua enkawl dan

Doctor-te chuan nau piang tharte chu Erythroblastosis Fetalis'' vei te chu thisen tlakchhamna leh hyperbilirubinemia'' (jaundice) te enkawlin an enkawl thin. Enkawlna kawng hrang hrang chu:

• Phototherapy: Hei hian hyperbilirubinemia enkawl nan light a hmang thin. He êng hian bilirubin chu naute taksa atanga awlsam taka chhuak thei thilah a chantir a ni.
• Thisen pek: Nausen pian hnuah thisen sen a mamawh a, thisen sen (red blood cells) a neih tlem theih nan thisen pek a ngai mai thei.
• Erythropoiesis Stimulating Agents (ESA): Hengte hi thisen pek ngai khawpa na lo thisen tlakchhamna enkawlna atana duhthlan tur a ni thei. Naute chu thisen sen hrisel tak siam turin iron supplement nen pek a ngai mai thei.

A nasat chuan naute hian puitu enkawlna a mamawh thei a, chu chu ventilator leh IV fluids te hi a ni.

Hetiang dinhmun hnu hian naute chungah eng nge thleng?

A result chu i naute symptoms nasat danah a innghat. Anemia na tak leh hyperbilirubinemia te hi enkawl loh chuan thihna thlen thei a ni.

Mahse, Erythroblastosis Fetalis vei naute chu uluk taka enkawl an nih chuan an dam khawchhuak thei a ni. Naupai lai leh/ emaw nau neih hnuah pawh an thisen sen (red blood cells) tihpun nan thisen pek an ngai mai thei. Doctor chuan thla engemaw zat chhung chu harsatna a awm loh nan a enfiah a ngai dawn a ni.

Hei hi a veng thei lo em ni?

A theih ngei ang! Erythroblastosis Fetalis hi naupai laiin thisen chi test leh venna damdawi hmanga ven theih a ni hle .Dinhmun. Rh-negative i nih chuan i taksain Rh-positive thisen laka antibody a siam loh nan Rh immune globulin (Rh immune globulin - RhIg emaw RhoGAM®) i ei thei ang. He damdawi hi naupai kar 28-ah, naupai tawp atanga darkar 72 chhungin (nau neih hnuah, nau pai) leh naupai laiin thisen chhuak nasa tak i neih chuan (first trimester-ah pawh) i ei a ngai a ni.

Hei hian i thisen Rh-positive thisen a luh hmaa he damdawi hi i ei phawt chuan a thawk thei a ni. Chuvangin naupai enkawlna hmunah chuan a bik takin an thlir a ni.

I doctor zawh tur thil

Hemi chungchanga zawhna dang i neih chuan i doctor emaw nurse emaw zawh hreh suh. Entirna thenkhat chu hetiang hi a ni:

• Ka thisen hi eng nge ni?
• Ka ngaihtuah tur antibodies'' a awm em?
• (Erythroblastosis Fetalis) hi ka ngaihtuah tur em ni?
• Monitoring dang emaw, clinic tlawh fo emaw ka mamawh ang em?
• Rh immune globulin (RhIg) ka ei a ngai dawn em ni?
• Engtikah nge appointment ka siam ang emaw, emergency care ka zawn ang?

Nu chu Rh-positive a ni a, naute chu Rh-negative a nih chuan eng nge thleng ang?

Hei hi thisen chi inrem lohna ngaihtuah tur a ni lo tlangpui. Rh-negative nausen hian nu immune system-in a beih theih Rh-antigen a nei lo. Thisen chi hrang hrang inmil lohna hmuh tur awm lo dang a awm loh chuan hei hi harsatna a ni tur a ni lo.

Thil pawimawh tak tak hriat reng tur

I taksa hriselna (immune system) hian i nausen piang lai chu a bei thei tih ngaihdan hi a hlauhawm hle. Mahse chanchin lawmawm tak chu heng thisen inrem lohna hlauhawm tak takte hi a tam lo hle. Tin, doctor-te chuan heng harsatnate hi a thlen loh nan theihtawp an chhuah thin. Thisen chi test hi nau neih hmaa enkawlnaah chuan tih ngei ngei tur a ni. Tin, i naute tana hlauhawm thei thisen chi hrang hrang inmil lohna enfiah leh enkawl hi nau neih hmaa enkawlnaah hian a awm tawh a ni. I doctor chuan i naute leh i naute himna tur kawng tinrengah a awmpui ang che. Chuvangin, a tul lovah hlauthawng suh la, doctor thupek chu uluk takin zawm rawh. Tichuan nang leh i naute chu in hrisel thei ve ve!