Darthlalang i en a, rang taka sam dum pahnih khat i hmuh chuan tlem chuan i hlauthawng a, i lungngai hle a ni lawm ni? "Aw, tunah pawh ka tar tawh" tih i ngaihtuah hun hi chhiar sen loh a awm ngei ang. Mi thenkhat tan chuan an sam chu an naupan lai atang tawhin a rawn sen tan a, a chang chuan sikul an la kal lai pawhin a rawn sen tan thin. Engvangin nge hetiang hi a lo awm tak tak? Kan upa chho zel vang mai mai em ni? Damdawi lam zirchianna hnuhnung ber chuan hei hi kan taksa ngeia inthlak danglamna tlemte, kan zinga tumahin kan ngaihtuah ngai loh vang a ni thei tih hmuhchhuah a ni.
Sam rawng pe theitu heng cell mak tak takte hi engte nge ni?
A awlsam zawngin, i sam hian a rawng dum leh sen mawi tak a hmu a, a chhan chu i sam zungbun bul hnaia cell chi khat bik tak a awm vang a ni. Heng pigment stem cells , a dik zawk chuan ``Melanocyte Stem Cells - McSCs`` kan ti a. Hengte hi kan sam rawng factory-a kan hman ber berte an ni.
Mahse heng stem cell te hian sam hi direct-in an rawn colour thei lo. Chutiang ti tur chuan an puitlin hmasak a ngai a, "melanocytes" an ni hmasa tur a ni. Heng melanocyte te hi sam rawng pe theitu pigment siamtu an ni.
Chuvangin i sam a hrisel leh a dum chhan chu heng stem cell te hi hun kal zelah an puitlin a, pigment cell an lo ni a, an hna an thawk tha hle a ni. Mak tak maiin heng pigment stem cell te hi kum tam tak an dam a, mahse sam zung siamtu cell dangte hmain an thi a ni. Mi thenkhat chuan an upat deuh deuh chuan an sam an hloh ngai lo, mahse an sam chu a var vek tawh tih i hre tawh mai thei. Hetah hian a chhan chu. Hair shaft cell te hian hna an la thawk reng a, mahse hair shaft siamtu cell te chuan hna an thawk tawh lo.
‘Stuck’ tih awmzia chu eng nge ni? Hmuhchhuah thar ber!
Hun rei tak chhung chu doctor leh scientist-te chuan heng stem cell te hi hmun khatah an awm reng a, a tul hunah an puitling a, an hna an thawh zawh veleh an thi ta niin an ngai a. Mahse zirchianna thar ber chuan he thawnthu hi a thlak danglam vek a ni.
Thil thleng tak tak hi thil buaithlak zawk leh mak zawk a ni. Heng cell te hi rulhut rawng thlak danglam ang mai an ni. Chu chu, hmun khata awm ai chuan, sam zung hmun hrang hrang inkarah an kal thei a, an nihna an thlak danglam thei tihna a ni.
He thil hmuhchhuah thar ang hian heng cell te hian cycle hrang hrangin hna an thawk a ni. Chu chu:
1. Initial stage: Stem cell puitling lo angin an tan thin.
2. Hnathawh: Chumi hnuah sam ruh hmun dangah a kal a, a puitlin a, sam rawng pe thei tur pigment te a siam chhuak ta a ni.
3. Hmuh lehna zinkawng: Hna thawh zawh a nih chuan chu cell te chu an dinhmun hmasa, chu chu stem cells dinhmun ah an kir leh a, an awmna hmunah an kir leh thin.
Hetiang cycle hi a kal zel chhung chuan kan sam hian rawng a nei chho zel ang.
Chuti a nih chuan khawiah nge buaina chu?
Zirchiangtute chuan kan tar chhoh zel chuan heng stem cell hlu tak takte hi a chang chuan sam ruh chhunga hmun dik lovah an tang thin tih an hmuchhuak. Hair shaft hmun pakhat, follicle bulge an tihah an tang a ni. An tlakbuak chuan an cycle an zo thei lo va, chu chu an puitlin thei lo va, pigment siamna tur an kalna tur hmunah an kal thei lo tihna a ni.
A rah chhuah chu? Hair shaft thar hian rawng a hmu lo. Chuvangin a rawn chhuak a, a var emaw, a dum emaw a ni.
Hetiang kalphung hi tlem han sawifiah leh ila.
| Indawtdan | Eng dang nge (simply) . |
|---|---|
| Sam naupang hrisel tak | Stem cells (McSCs) te hi an migrate dik a, an puitling (melanocytes an ni) a, sam ah pigment an pe bawk. Tichuan an dinhmun hmasa berah an kir leh ta a ni. He cycle hi a chhunzawm zel a ni. |
| I tar hunah/i sam a var hunah | Stem cell thenkhat chu hair shaft hmun thenkhatah ‘bulge’ an tih ah an tang a. Hma lam pan thei lo leh puitling thei lo an ni. |
| Final result a ni | Pigment siam thei tur cell a awm loh avangin sam lo piang thar chu a var emaw, a sen emaw a ni. |
Hei hian cancer chungchangah pawh clue a pe em?
Awle. He thil hmuhchhuah hi sam dum tan chauh ni lovin, vun cancer hriatthiamna atan pawh a pawimawh mai thei . A bik takin, vun cancer chi khat na ber , melanoma , chu heng pigment cells (melanocytes) atang hian a lo piang chhuak thin.
Melanoma cancer cell-te mizia hlauhawm ber pakhat chu awlsam taka an nihna an thlak danglam theihna hi a ni. Damdawi lamah chuan hei hi ‘plasticity’ an ti a. Hetiang theihna avang hian melanoma cancer hi control harsa leh tihdam vek a harsa hle.
He zirchianna thar hian kan pigment cell pangngai, hrisel tak takte pawh hian ‘plasticity’ sang tak an nei tih a tarlang. Chuvangin, tunah chuan scientist-te chuan he melanoma cancer cell-te thiltih hlauhawm tak hi an lo chhuahna pigment cell pangngai ngeia he ‘danglam theihna’ vang pawh a ni thei niin an ring.
Chuti a nih chuan hei hi damdawi hmuh theih a ni ang em?
Hei hi mi zawng zawng rilrua zawhna awm chu a ni. Tunah chuan he ‘stuck’ process hi hmuhchhuah a ni tawh a, zirchiangtute thil tum dang chu heng stuck cells te hi chhuah tir a, an awmna tur dik takah thawn kir leh theihna tur kawng zawn a ni Chutianga tih theih a nih chuan sam a rawn sen loh nan a titawp thei a, sam dum leh thei tawh lo pawh a ni mai thei.
Mahse hei hi research stage-ah a la awm a ni. Hei hi damdawi a la awm lo. Amaherawhchu, mi thenkhatin natna dang damdawi an pek avangin an sam dum chu a rawn sen leh ta niin report a awm bawk. Chu damdawite chuan tum loh takin heng cell tangte hi a ‘zalen’ a ni mai thei.
Stress leh meizuk ang chi thilte hian heng cells blockage hi a nghawng em tih pawh kan chhui belh a ngai a, a chhan chu heng thilte hian taksa chhunga thil kalphung tam takah nghawng tha lo tak a nei tih kan hria a ni.
Take-Home Thuchah a ni
- I sam a var chhan ber chu sam rawng pe thei stem cell bik, Melanocyte Stem Cells tia koh te hi sam zung chhunga hmun dik lovah ‘chung’ an nih vang a ni.
- Hei hi science lama thil hmuhchhuah thar a ni. Researcher-te chuan heng cell tangte hi chhuah zalen thei tur leh sam dum a nih loh nan damdawi zawngin an zawng mek a ni.
- Hetih lai hian sam a sen loh tur damdawi bik a awm lo. Market-a thil awmte chu fimkhur rawh.
- Enkawlna chiang tak a awm hma chuan, ei leh in inthlau tak ei te, zu in loh te, leh stress control te ang chi nunphung hrisel tak tak i hman hian i hriselna zawng zawng leh i sam hriselna a pui ang.
- I vun emaw, i sam emaw-a inthlak danglamna rang tak, danglam tak (e.g., hmun thar, rawng dum chak tak) i hmuh chuan hlau suh, mahse i doctor hnenah thurawn dil ngei ang che.
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