I taksaah hian lump mak tak mai i nei em? (Hamartoma) a ni thei! Hemi chungchang hi han sawi ila.

I taksa hmun khatah lump te tak te emaw, tumor emaw i nei a, "Hei hi eng nge ni?" A nih loh leh doctor-in ``Hamartoma'' a tih che kha eng nge ni tih i ngaihtuah ngai em? He ``Hamartoma'' hi eng nge ni tak tak? A awlsam zawngin, i hriatthiam theih dan tur angin sawi ila.

`(Hamartoma)` tih hi eng nge ni? A awlsam zawngin i hrethiam ang u!

Awle, tunah chuan he `(Hamartoma)` hi eng nge a nih i en ang u. A awlsam zawngin sawi ila, benign, tumor te tak te a ni. Kan taksaa awm tlangpui cell chi hrang hrang atanga siam a ni. Mahse a danglamna tlem a awm. Chu chu, heng cell te hi eng emaw chen mumal lo tak, inrual lo takin an inzawm khawm a, he tumor hi an siam ta tihna a ni. Infiamna chi khat thenkhat chu mumal taka dah ai chuan pile-a dah ang mai a ni . `(Hamartoma)` tih thumal hi Grik tawng pahnih atanga lo chhuak a ni. ``Hamartia`` tih awmzia chu ``fault`` emaw ``deficiency`` emaw tihna a ni. ``Oma`` tih awmzia chu ``tumor`` tihna a ni. Chuvangin, hei hian chhiatna chi khat avanga tumor lo awm tihna a ni.

A pawimawh ber chu heng ``Hamartomas`` te hi cancer an ni lo tih hi a ni . Cancer cell angin taksa pum puiah an darh lo . Chuvangin ngaihtuahawm tur a awm lo. Mahse, an awmna hmun azirin a chang chuan harsatna tenau te an thlen thei a ni.

He `(Hamartoma)` hi taksaah khawiah nge a lo thanlen theih ang?

Heng ``Hamartomas`` te hi kan taksa khawi hmunah pawh a lo awm thei tak tak a ni. Mahse hmuh tamna hmun tlemte a awm.

• Lungs : A tam zawkah chuan heng ``Hamartomas`` te hi lungah an lo awm thin. Lung-a benign tumor hmuhchhuah zinga 10% chauh hi hetiang chi hi an ni an ti. A châng chuan, chhan dang vanga chest `` X-ray`` lak a nih chuan accident-in an hmuchhuak ṭhin.
• Vun: Hamartomas hi lu leh kawr ah a awm tam ber a, a bik takin hmai, hmui leh beng hnung leh beng hnuaiah a awm tam ber. A châng chuan pianpui chhinchhiahna ang maiin an lang thei bawk.
• Thinlung : Hengte hi thinlungah pawh a lo thang lian thei bawk. Cardiac rhabdomyoma hi hamartoma chi khat, thinlunga lo awm thin a ni. Chûngte chu nu pum chhungah ( naupai laiin ) emaw, naute tê tê angin emaw hmuh tur a awm fo. A tlem hle nachungin, hengte hi naupang tête thinlunga lo awm tam berte an ni.
• Thluak:Tumor chi khat, hypothalamic hamartoma an tih hi hypothalamus-ah a lo piang a, chu chu thluak peng pakhat a ni a, chu chuan taksaa thil pawimawh tam tak a tidanglam thei a ni. Heng tumor te hi pian tirh lamah a awm thei a, mahse naupan lai emaw, tleirawl lai emaw chauhvin a lan chhuah dan a lang fo thin. Anni hian symptoms te chu seizures , mitdelna leh precocious puberty te a thlen thei a ni .
• Hnute: Hmeichhia hnute a benign lumps 5% vel chu hamartomas a ni thei. Hmeichhia kum 35 chunglam ah an tam ber.

Chu bakah, hamartomas hi kidney, spleen, thyroid gland, leh ruh ang chi hmunah te pawh a lo awm thei a, hei hi genetic condition thenkhat PTEN hamartoma tumor syndrome (PHTS) te nen pawh a inzawm thei bawk.

He `(Hamartoma)` hi taksa pum puiah a darh em?

Hei hi mi tam tak tan chuan harsatna lian tak a ni. Ni lo, ``Hamartoma`` hi cancer angin taksa pum puiah a darh lo. Chu chu a siamna hmunah a awm reng tihna a ni. Mahse, a chang chuan he tumor hi a lian deuh a nih chuan a bul hnaia tissue emaw organ hrisel tak takte chu a nawr thei a, chhiatna engemaw zat a thlen thei bawk. Mahse chutiang chu a thleng tlem hle.

`(Hamartoma)` nena inzawm condition dang a awm em?

Ni e, Hamartoma hi genetic condition hmuh tur awm lo thenkhat nen pawh a inzawm thei. Hetiang dinhmunah hian Hamartoma hi gene pakhata mutation avanga lo awm a ni.

• (Pallister-Hall syndrome - PHS): He natna hi gene `GLI3`-a mutations nen a inzawm a ni. Thluaka `(Hypothalamic hamartomas)` vei zinga 5% vel pawhin he `PHS` natna hi an nei thei bawk.
• Tuberous sclerosis: He natna hian taksa peng hrang hrang thluak, thinlung, kal, vun, leh mit ah te ``Hamartoma'' a siam thei a ni.
• ( Neurofibromatosis Type 1 - NF1): Hei hi genetic condition hmuh tur awm lo tak a ni bawk. Hei hian taksa pum puia nerve-ah ``Hamartoma`` a lo awm thei a ni.
• (PTEN hamartoma tumor syndrome - PHTS): Hei hi `PTEN` gene-a mutations nena inzawm natna chi khat a ni. `(Cowden syndrome)` leh `(Bannayan-Riley-Ruvalcaba syndrome - BRRS)` te hi hei hi subtype a ni. `(Hamartoma)` hi hnute, nausen pum, thyroid gland, chaw kawng (`GI tract`), leh vunah te a lo awm thei.
• Peutz-Jeghers syndrome (PJS): Hei hi gene STK11/LKB1-a mutation nen a inzawm a ni. PJS vei te hian lung, pum, bladder, small intestine, colon, leh rectum-a hamartomas an vei theihna a sang hle.

Hetiang genetic condition i neih chuan i doctor chuan genetic test emaw counseling emaw a rawt thei ang.

`(Hamartoma)` natna lan chhuah dan chu engte nge ni?

A tam zawkah chuan heng `(Hamartomas)` te hian symptom (`asymptomatic`) an lantir lo. Chu chu i taksaah harsatna nei lovin i nei thei tihna a ni. Mahse, a chang chuan he tumor hi a lo seilian tlem a, a hnuaia tissue te a press chauhvin symptoms a lang thin. Chutiang a nih chuan a natna lan chhuah dan chu `(Hamartoma)` awmna hmunah a innghat a ni. Entirnan, lung chhunga `(Hamartoma)` a lo lian chuan khuh leh thawk harsa ang chi thil i tawng thei. Pakhat chu thluaka a awm chuan, a hmaa kan sawi tawh ang khan, seizures leh mit lama harsatna a awm thei.

Hamartoma hi engte nge ni?

Scientist-te chuan Hamartoma awm chhan dik tak hi an la hre lo. Mahse, kan sawi tawh ang khan, genetic condition thenkhat nen a inzawm tlat a ni. Heng genetic conditions te hi rochun a ni fo thin. Chu chu nu leh pa zinga pakhat hnen atanga rochun genetic mutation avanga lo awm thei an ni tihna a ni.

Hamartoma hian harsatna a thlen thei em?

Hamartoma tam zawk hi chu a na lo hle. Mahse, taksa peng emaw, taksa insiam dan emaw tichhe thei khawpa lian an nih chuan harsatna an siam thei a ni. Entirnan, thinlunga cardiac rhabdomyoma a awm chuan thinlung hnathawh a tibuai chuan heart failure a thlen thei a ni. Chutiang bawkin thluaka hypothalamic hamartoma hian hypothalamus hnathawh a tihbuai chuan hormone imbalances leh cognitive impairment a thlen thei bawk. Mahse lungngai suh, i doctor chuan hamartoma chu a enfiah thei a, a tul chuan a paih chhuak thei bawk.

Engtin nge `(Hamartoma)` hi hriat chhuah a nih?

Hamartomas hian natna lan chhuahna a nei lo fo va, chuvangin natna dang scan laiin a thleng maiin hmuhchhuah a ni. Hamartoma hi tumor a nih leh nih loh hriat a harsa thei a, a bik takin a awmna hmun a zirin. I doctor chuan a enfiah ang che a, i medical history a zawt ang che. A tam zawkah chuan hamartoma a nih leh nih loh finfiah nan test dang neih belh a ngai dawn a ni.

Diagnostic test te hi engte nge ni?

• X-ray: Radiation test hniam tak, ruh leh soft tissue thlalak lakna a ni. Lung chhunga hamartomas hi X-ray-ah chuan "popcorn" ang maiin a lang fo thin. Hei hian cancer tumor atanga thliar hran nan a pui thei a ni.
• Ultrasound: Sound wave hmangin taksa chhunga tissue nem tak takte thlalak a la thin.
• CT scan (Computed tomography): X-ray tam tak hmanga taksa chhunga tissue nem leh ruh awmte cross-sectional picture lakna scan a ni. Lung hamartomas hmuhchhuah nan CT scan hi a tangkai hle.
• MRI (Magnetic resonance imaging hmanga thil tih a ni): 1.1.Magnet lian tak leh radio wave hmangin taksa chhunga tissue nem tak takte chipchiar taka thlalak lak a ni.
• Mammogram: Dose hniam test, hnute tissue enfiahna a ni. Breast hamartoma tam zawk hi mammogram neih laiin hmuh a ni a, hei hi cancer enfiahna atan hman a ni.
• Biopsy: Hemiah hian doctor pakhatin tumor te tak te a la a, laboratory-ah a thawn a. Chutah chuan ``Pathologist`` chuan microscope hmangin cell te chu a en a. He ``Biopsy`` hi benign tumor, ``Hamarthoma`` ang chi, cancer tumor emaw a nih leh nih loh chiang taka hriat theihna awmchhun a ni. Hei hi natna hriat theihna kawng chiang ber a ni.

Hamartoma hi engtin nge enkawl a nih?

Enkawlna chu hamartoma awmna hmun leh symptoms i neih leh neih loh te a innghat a ni.

• Harsatna a awm loh chuan: Tumor hian harsatna a thlen loh emaw, a lan chhuah loh emaw a nih chuan doctor chuan enkawl loha enfiah a rel thei a ni. Chumi awmzia chu a lian chho zel em tih leh a danglam zel em tih chu a hun hunah an scan thin tihna a ni.
• Symptoms a awm emaw, cancer rinhlelhna a awm chuan: Chutiang hunah chuan tumor lakchhuahna tur surgery hi a enkawlna ber a ni fo thin.

Hamartoma lakchhuahna atana hman tur surgery bikte chu engte nge ni?

Hei pawh hi hamartoma awmna hmun azirin a danglam thei bawk. Lung hamartoma tan chuan:

• Wedge resection: Hetah hian tumor awmna lung atanga wedge ang chi te tak te chu an tan a, an la chhuak thin. Tumor rual hian a chhehvela tissue hrisel thenkhat pawh lakchhuah a ni bawk.
• Lobectomy: Lung lobe pakhat chu lakchhuah vek a ni a, chu lobe-ah chuan hamartoma chu a awm a nih chuan. Kan lung dinglam hian lobe pathum a nei a, kan lung veilam hian lobe pahnih a nei bawk.
• Pneumonectomy: Lung pum pui chu lakchhuah vek a ni. Mahse, hamartoma tan chuan hetiang surgery lian tak neih a ngai hi a tlem hle.

Thluaka `(Hypothalamic hamartomas)` tan chuan:

• Resection surgery: Surgeon chuan tumor chu a cut chhuak a, a paih chhuak thin.
• Ablation: Tumor hi heat sang tak emaw laser radiation hmanga tihchhiat a ni.
• (GammaKnife® radiosurgery): Hei hi hmanlai surgery a ni lo. Radiation hian tumor chu a tichhe vek a, a chungah chakna chak tak a kaihruai a ni. Surgery ang bawkin tissue hlauhawm tak tak chu chiang takin a paih chhuak thin.

`(Hamartoma)` ka neih chuan eng nge thleng ang?

Hamartoma tam zawk hi chu a na lo hle a, chuvangin hlauthawng suh. Hamartoma hian taksa peng pakhat a nghawng emaw, a lian tawk a, chhiatna a thlen thei a nih chuan, a tlangpuiin operation hmangin a chinfel theih a ni. A châng chuan hamartoma chu paih chhuah a harsa thei bawk. Entirnan, hypothalamic hamartomas thenkhat chu optic nerve bulah a lo awm a, chu chu operation hmangin a tichhe thei a ni.

Chuvangin, i doctor nen uluk taka inbiakna neih a pawimawh hle a, i hamartoma hi lakchhuah a ngai em tih hriat a pawimawh hle a, a nih chuan eng harsatna emaw, hlauhawmna emaw a thlen theih tih hriat a pawimawh hle.

``Hamartoma'' hi cancer a ni thei ang em?

Hei hi mi tam takin an hlauhna dang a ni. Hamartoma cancer-a a chan theihna chance a tlem hle. Chu chu a thleng tlem hle tihna a ni. Mahse hei hi a ni. Hamartoma nena inzawm genetic condition thenkhat (entir nan, Cowden syndrome, PHTS subtype) hian cancer vei theihna a tipung thei a ni. Chutiang a nih chuan hamartoma hian cancer vei theihna a tipung lo va, genetic condition a ni zawk. Chuvangin hetiang genetic condition i neih chuan cancer screening neih fo a pawimawh.

Ka doctor hnenah eng nge ka zawh ang?

``Hamartoma'' i vei tih i hriat veleh chuan i doctor zawh tur tlemte a awm. Heng zawhnate hi zawh hreh suh:

• Engvangin nge he `(Hamartoma)` hi ka lo siam chhuah?
• He `(Hamartoma)` hi ka paih chhuah a ngai em?
• Hei hian enkawl a ngai tih tilangtu symptoms te chu engte nge ni?
• He ``Hamartoma`` hi natna khirh tak dang chhinchhiahna a ni thei ang em?
• Genetic counseling emaw, test emaw hi keimah emaw, ka chhungte tan emaw a hlawkpui ang em?

A tawp berah chuan thil hriat reng tur (Take-Home Message) .

Okay, chuti a nih chuan kan sawi tawh atang hian `(Hamartoma)` chungchangah hian ngaihdan tha tak i nei niin ka hria. A pawimawh ber chu, `(Hamartoma)` hi a tam zawkah chuan a hlauhawm lo. Cancer an ni lo va, taksa pum puiah an darh lo. A tam zawkah chuan enkawl an ngai lo. Mahse, symptoms a awm chuan, emaw, doctor-in rinhlelhna a neih chuan surgery hmanga lakchhuah theih a ni a, buaina chu chinfel theih a ni.

Doctorin ``Hamartoma'' i nei tih a hrilh che chuan a tul lovah hlau suh la, i doctor nen uluk takin inbiakna nei la, i tan eng nge a tha ber tih chu ngaihtuah rawh. I hriselna enkawl hi a pawimawh ber a ni!

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