I taksaah iron i nei tam lutuk em? Hemochromatosis chungchang hi han sawi ila!

A châng chuan chhan awm lovin a danglam bîk takin i chau tih i inhria em? I ruh, a bik takin i khup leh ke ruhte chu a na a, i vun chu a sen deuh emaw, bronze emaw a ni em? Heng thilte hi "kan tar dan chauh" tiin kan hnawl fo thin. Mahse hengte hi kan taksaa iron level hlauhawm taka a punna dinhmun chhinchhiahna a ni thei. He natna hi damdawi lam chuan Hemochromatosis an ti a . Hei hi vawiinah kan sawi tum chu a ni.

A awlsam zawngin, Hemochromatosis hi eng nge ni?

Hemochromatosis hi i taksain iron a khawlkhawm tam lutuk a ni . Mi thenkhat chuan " iron overload " an ti bawk.

A tlangpuiin kan taksa hian kan ei leh in a\angin iron mamawh zat chauh a hip lut \hin. Mahse, hemochromatosis vei te tan chuan taksain a mamawh aia tam iron a hip lut thin. Buaina chu taksa atanga he thir tam lutuk hi paih chhuah theih dan a awm lo.

Chuti a nih chuan taksa hian khawiah nge he thir tam lutuk hi a dahkhawm? I ruhroah a awm a, chubakah i liver , thinlung , vun, pituitary gland, leh pancreas ang chi organ pawimawh tak takah pawh a awm bawk. Hun a kal zel a, he thir khawlkhawm hian chu taksa pengte chu a tichhe tan ta a ni. Enkawl loh chuan heng taksa peng hrang hrangte hian hna an thawk tawh lo thei a ni.

He natna hi chi hnih a awm a.

He dinhmun hi chi hnih ah then theih a ni ber.

1. Primary Hemochromatosis: Hei hi a tam ber a ni. Hrilhfiahna a ni. A awlsam zawngin, he natna hi vei tur chuan i nu leh pa te hnen atangin gene chhia chu i rochun a ngai a ni. Nu leh pa pakhat chauh atanga i rochun chuan natna hi i nei lovang, mahse gene kengtu i ni mai thei.

2. Secondary Hemochromatosis: Hei hi chhan dang vang a ni. Entirnan, thisen tlakchhamna nasa tak ang chi natna avanga thisen pek fo ngai mi pakhatah hian he natna hi a awm thei a ni.

Eng thilin nge hetiang dinhmun hi a thlen?

Hei hi eng chhan nge ni tih i lo en ang u.

Hriselna atanga lo piang chhuak (Primary Hemochromatosis) .

Kan taksa hian gene pakhat `HFE` tih a nei a. Hei hian kan ei leh in atanga iron kan lakluh zat a thunun a ni. He `HFE` gene-a mutation pahnih, `C282Y` leh `H63D` te hi hereditary hemochromatosis vei tam zawk chhan a ni.

Tin, gene dang, `HJV` leh `HAMP`-a mutations hian mi tlemte (10%-15% vel) ah pawh he natna hi a thlen thei bawk. Heng genes-in a nghawngte hian an naupan laiin symptoms an nei tlangpui.

Damdawi lam thil dang (Secondary Hemochromatosis) avanga lo awm a ni.

Hetiang chi hi thisen pek fo avanga lo awm a ni tlangpui a, hei hi thisen pek fo thin vang a ni a, hei hi thisen tlakchhamna nasa tak (sickle cell anemia ang chi) emaw ruhro tha lo (bone marrow failure ang chi) vang a ni. Thisen i pek huna thisen sen (red blood cells) pek thinte hian iron a pai tam hle. Taksain he thir hi lakchhuah dan tur a neih loh avangin an pungkhawm tan ta a ni.

Tin, liver chhiatna, entirnan, fatty liver disease ( cirrhosis ) emaw, chronic hepatitis B emaw C emaw avanga taksaah iron a awm khawm thei bawk.

Tute nge he natna vei theihna sang zawk?

Tu pawhin hemochromatosis an vei thei a, mahse mi thenkhat chu an hlauhawm zawk.

Nang pawhin heng symptoms te hi i nei ve em?

Hemochromatosis vei zinga a chanve vel chuan symptom engmah an nei lo. Mipa hian kum 30 leh 50 inkarah symptoms an nei tlangpui a, hmeichhia erawh chuan kum 50 an tlin hnuah emaw, menopause hnuah emaw symptoms an nei fo thung.

Engtin nge hei hi i hmuh theih, Doctor?

Heng chhinchhiahnate hi natna dangah hmuh theih a nih avangin, a chang chuan hriat chian a harsa thei hle. I doctor chuan i chhungkaw medical history a zawt ang che a, taksa enfiahna pawh a nei ang.

Tin, heng test te hi tih theih a ni bawk:

• Thisen test: Hetah hian test lian pahnih tih a ni.
• Transferrin Saturation: Hei hian thisen chhunga iron phurtu protein (transferrin) nena iron inzawm zat a tehna a ni.
• Serum Ferritin: Hei hian thisena iron dahkhawmtu protein (ferritin) a tehna a ni.

Heng test-te hian i iron level a sang tih a hriat chuan i doctor pawhin hemochromatosis thlentu gene i neih leh neih loh enfiah turin genetic test a ti thei bawk.

• Liver Biopsy: Doctor chuan liver atanga tissue te tak te a la a, microscope hmangin liver ah chhiatna a awm em tih a enfiah thin.

• MRI scan: Hei hian i taksa peng hrang hrangte thlalak chiang tak a la thei a, thir a awm leh awm loh a en thei bawk.

Enkawlnate chu engte nge ni?

Primary Hemochromatosis i neih chuan a enkawl dan a awlsam hle. Schedule bik neia i taksa atanga thisen lakchhuahna a ni. Hei hi Phlebotomy an ti a.

Phlebotomy tih a ni

Hei hi thisen pek nen a inang a ni. Doctor emaw trained nurse emaw chuan i kut vein pakhatah needle a thun a, thisen bag chhungah thisen a la lut a.

• Enkawlna hmasa ber: A tirah chuan iron level a normal leh hma loh chuan kar khatah vawi khat emaw vawi hnih emaw damdawi inah i kal a ngai dawn a ni. Hei hian thla engemaw zat emaw, kum khat emaw a daih thei.
• Maintenance therapy: Iron level a lo awm tawh chuan thisen pek tamna chu a tlahniam a, a tlangpuiin kum khatah vawi hnih atanga vawi li vel a ni.

Damdawi hmanga enkawl (Chelation Therapy) .

Secondary hemochromatosis i neih chuan, emaw, i thisen kalna kawng a chak tawk lo a nih chuan, i doctor chuan `Chelation Therapy` tih damdawi a pe thei che a ni.

Hetiang dinhmun hi in lamah enkawl theih a ni em?

Phlebotomy enkawl mek chuan a ei leh inah inthlak danglamna lian tham a neih a ngai lo tlangpui a, a enkawlna ngei hian an iron level a control avangin. Mahse, harsatna i neih theihna tur tihtlem nan a hnuaia mite hi i ti thei ang:

• Zu hi pumpelh vek rawh. Zu hian thin a tichhia a, he natna nen hian a hlauhawm hle.
• Nga raw emaw, shellfish emaw ei loh tur. Heng zinga bacteria hian iron level sang tak nei te tan natna khirh tak a thlen thei a ni.
• Vitamin C supplement ei loh tur. Amaherawhchu, thei leh thlai chi hrang hrang, vitamin C awmna ei hi harsatna a awm lo.
• Iron pill emaw iron awmna multivitamin emaw ei loh tur.
• Iron-fortified breakfast cereal ei loh tur.