I taksaah hian thir a tam lutuk em? Hemochromatosis chungchang hi i zir dawn teh ang.

I chau fo a, ruh natna i nei fo em? A chang chuan hengte hi thil pangngaiah kan ngai a, kan ngaihsak lo. Mahse heng thilte hi kan taksaa iron tam lutuk chhinchhiahna a ni thei bawk. Vawiin hian chutiang dinhmun pakhat, "Hemochromatosis" chungchang kan sawi dawn a ni. Hei hi hming hriat loh deuh ni mahse, a chanchin hriat a pawimawh hle.

A awlsam zawngin, hemochromatosis chu eng nge ni?

Hemochromatosis hi i taksain iron a khawlkhawm tam lutuk a ni. Mi thenkhat chuan "iron overload" an ti bawk. A tlangpuiin kan intestines hian kan ei leh in atang hian kan taksa mamawh iron zat chauh a hip lut thin. Mahse hemochromatosis vei te tan chuan taksain a mamawh aia tam iron a hip lut thin. Buaina chu he thir tam lutuk hi tihbo dan tur a awm lo. Chuvangin taksa chuan he iron tam lutuk hi i ruhkawr leh taksa peng pawimawh tak tak liver, heart, leh pancreas-ah te a dahkhawm thin.

Hetiang dinhmun hi chi hnih a awm a.

He dinhmun hi chi hnih ah then theih a ni. 1. Primary Hemochromatosis: Hei hi thlahtute atanga lo piang a ni. Chu chu chhungkaw member kaltlangin genes hmanga inthlunzawm a ni tihna a ni. A dik tak chuan he natna hi i vei theih nan chuan i nu leh pa hnen atangin gene chhia chu i dawng tur a ni. 2. Secondary Hemochromatosis: Hei hi chhan dang vang a ni. Entirnan, he natna hi damdawi lama harsatna nei, thisen pek fo ngai (e.g., thalassemia) emaw, thin natna dang nei emaw teah a awm thei a ni.

Hemochromatosis hi engte nge ni?

Hereditary avanga lo awm a ni

HFE gene hian kan taksain ei tur atanga iron a lakluh zat a control a ni. HFE gene-a mutation pahnih, C282Y leh H63D te hi hereditary hemochromatosis case tam zawkah hian mawhphurtu a ni. Gene dang pawh hian case tlemte (10%-15% vel) a thlen thei bawk. Chungte chu non-HFE hemochromatosis an ti a. HJV emaw HAMP emaw ang chi gene-a mutations a awm chuan kum naupan lai atanga symptoms a lang tlangpui. A châng chuan, naupang tê tê aṭangin liver chhiatna leh cirrhosis a awm thei bawk.Thil awmdan hi a lo awm ngei a rinawm.

Pawn lam thil dang (Secondary Causes) .

Hetiang chi hi mi pakhatin thisen tlakchhamna na tak ang chi natna a neih a, thisen pek fo a ngaih hunah a thleng tlangpui. Hei hi a chhan chu pawn lam atanga an hnena thisen sen (red blood cells) pek thinah hian Iron tam tak a awm vang a ni. Taksain he thir hi lakchhuah dan tur a neih loh avangin a pungkhawm tan ta a ni. Natna chi hrang hrang, cirrhosis emaw chronic hepatitis B emaw C emaw avanga thin (liver) a chhiat chuan iron a pung thei bawk.

Hemi atan hian tute nge hlauhawm ber?

A hnuaia thilte hi i neih chuan hemochromatosis i vei theihna a sang zawk. Hei hi chiang taka hrethiam turin table pakhat han en ila.

Hemochromatosis natna lan chhuahna chu engte nge ni?

Hemochromatosis vei zinga a chanve vel chuan symptom engmah an nei lo. Mipa tan chuan kum 30 leh 50 inkar atanga a lan tan tlangpui a, hmeichhia tan chuan kum 50 hnuah emaw, menopause hnuah emaw a lang fo thin. A lan chhuah dan tlangpui thenkhat chu hetiang hi a ni:

• Joint pain , a bik takin ruh leh khup ah.
• Chronic fatigue chhan awm lovin.
• Chhan awm lovin taksa rihna tihtlem .
• Vun chu bronze emaw grey emaw a lo ni ta .
• Pum natna .
• Mipat hmeichhiatna lama duhna tlahniam .
• Taksa sam tlakchham.
• Heart rate inthlak danglamna (Heart flutter).
• Foggy memory chu a buai deuh a, thluak foggy ang maiin a awm .

A châng chuan, natna hian heng chhinchhiahnate hi a lantîr lo va, chu ai chuan harsatna dang angin a rawn lang zâwk a ni. Entir nan:

• Liver lama harsatna, a bik takin cirrhosis
• Zunthlum natna
• Lungphung dik lo a awm
• Arthritis natna a ni
• Erectile dysfunction a awm thin

Engtin nge hei hi i hmuh theih, Doctor?

Heng symptoms te hi natna dang ah hmuh theih a nih avangin, a chang chuan diagnosis hi a buaithlak deuh thei a ni. Mahse symptoms i neih chuan, risk factors i neih chuan emaw, chhungkaw member pakhatin natna a neih chuan i doctor chuan a enfiah ang. Natna hriat dan tlangpui thenkhat chu hetiang hi a ni:

• Nang leh i chhungte damdawi lam chanchin zawh: Doctor chuan i chhungte zingah he natna, thin natna emaw, ruh natna emaw nei an awm em tih a zawt ang.
• Taksa enfiahna: I taksa enfiah a ni ang.
• Thisen test: Test lian ber pahnih tih a ni.

1. Transferrin saturation: Hei hian thisen chhunga iron phurtu protein transferrin nena iron a inzawm zat a tarlang a ni. 2. 2. A rilru a hah lutuk chuan a rilru a buai em em a.Serum ferritin: Hei hian taksaa iron dahkhawmtu protein ferritin level a teh a ni. Heng test-ah hian iron level sang tak a awm a nih chuan i doctor chuan hemochromatosis thlentu gene i neih leh neih loh hriat nan genetic testing nei turin a refer thei che a ni.

• Liver biopsy: Liver hmun te tak te tak te chu lak a ni a, microscope hmangin liver-ah chhiatna a awm em tih enfiah a ni.
• MRI scan: Magnet leh radio wave hmangin i taksa peng hrang hrangte thlalak chiang tak a siam thin.

Enkawlnate chu engte nge ni?

Hereditary hemochromatosis i neih chuan a enkawlna ber chu phlebotomy . A awlsam zawngin, hei hi i taksa atanga thisen chhuah hunbi neia lakchhuahna a ni . Sri Lanka rama thisen kan pek dan nen a inang hle. Doctor emaw, nurse trained emaw chuan i kut vein pakhatah needle a thun a, thisen engemaw zat a la chhuak thin. Hei hi a tum ber chu i thisena iron level awm zat chu a pangngaia awm leh hi a ni. Hei hi hmun hnih-ah a thleng a:

• Enkawlna hmasa ber: Iron level a normal leh hma loh chuan thisen lak nan kar khatah vawi khat emaw vawi hnih emaw damdawi in emaw clinic emaw i kal a ngai dawn a ni. Hei hian kum khat emaw a aia rei emaw a la ngai thei.
• Maintenance treatment: Iron level a normal leh tawh chuan thisen pek tamna a tlahniam thin. Hei hi kum khatah vawi hnih atanga vawi li tih thin a ni tlangpui.

Secondary hemochromatosis i neih chuan, emaw, i thisen kalna kawng a chak tawk lo a nih chuan, i doctor chuan chelation therapy tih damdawi a rawt thei ang. Hei hian i taksain i zun leh ek kaltlangin iron tam lutuk a tihbo theih nan damdawi pek che a huam a ni.

In lamah leh i nunphungah eng inthlâk danglamna nge siam theih?

Phlebotomy i tih chuan iron level control nana a puih avangin diet khauh tak zawm a ngai lo tlangpui. Mahse, harsatna i neih theihna tur tihtlem nan a hnuaia mite hi i ti thei ang:

• Zu hi pumpelh vek rawh. Zu hian thin (liver) chhiatna a tipung thei a ni.
• Nga raw emaw, shellfish emaw ei loh tur. Iron level sang tak nei te zingah natna thlen thei bacteria an awm thei.
• Vitamin C supplement ei loh tur. Mahse, vitamin C awmna natural foods (e.g. orange, tangerines) ei hian harsatna a awm lo.
• Iron supplement emaw iron awmna multivitamin emaw ei loh tur.
• Chawhmeh cereal iron dah tel (fortified) te ei loh tur.
• Iron tamna ei tur (e.g., oysters, duck, spinach) ei tlem rawh. Hemi chungchang hi doctor zawt rawh.Ngaithla la, hrechiang rawh.

Take-Home Thuchah a ni

• Hemochromatosis hi taksaah iron tam lutuk a khawlkhawmna a ni. A bul berah chuan thlah kal zelah a lo inher chhuak thin, genetic condition a ni.
• A lan chhuah dan chu hahna, ruh na, vun rawng danglam te a ni thei. Mi thenkhat chuan symptoms an nei lo thei.
• Symptoms i neih emaw, i chhungte zinga mi tu emaw hian he natna hi a vei a nih chuan doctor pan vat la, thurawn la rawh.
• A hmaa hriatchhuah leh enkawl (Phlebotomy) hian taksaa iron level a control thei a, taksa peng hrang hrang tihchhiat a veng thei bawk.
• Hei hi hlauh tur condition a ni lo. Damdawi inenkawlna leh thurawn mumal tak i neih chuan nun pangngai, hrisel takin i nung thei a ni.

Hemochromatosis, Iron overload, Liver natna, Ruh natna, Phlebotomy te a awm bawk