Leptin chungchang hi i zir belh ang u, a rukin i taksa rihna control nan a pui che a ni.

Kan rih zawng hi a chang chuan kan buai vek a ni lawm ni? Mi thenkhat chuan taksa rihna tihtlem an duh a, thenkhat erawh chuan taksa rihna hrisel neih reng an duh thung. Kan taksa chhungah hian kan taksa rihna control thei tur mechanism tlemte a awm tih i ngaihtuah ngai em? Leptin hi chutiang secret controller zinga mi a ni. Vawiin hian he leptin chungchang hi i hriatthiam theih tur awlsam takin i sawi dawn nia.

Leptin chu eng nge ni?

A awlsam zawngin, leptin hi i taksa thau cell, a nih loh leh adipose tissue -te siam hormone a ni. Hun rei tak chhunga i rihna control theihna tur signaling system tlemte ang mai a ni. Engtin nge chutiang chu a tih theih? Leptin hian i riltamna a thunun a, i chaw ei kham, a nih loh leh i rilru a hahdam bawk .

Hetiang hian han ngaihtuah teh: leptin hi i thluaka i taksaa thau i neih zat hrilhtu palai ang a ni. Scientist te chuan leptin hi tun hnai khan kum 1994 khan an hmuchhuak chauh a, chuvangin zirchianna tam tak a la awm a, a hnathawh dan dik tak hriatthiam nan. Leptin hi weight management, Alzheimer’s disease , reproductive health, leh infertility -a a chanvo te zirchian a ni tawh a ni.

Leptin hian taksa rihna a control tih i hriat chuan, "Aw... chuvang chuan leptin control dan tur ka ngaihtuah chhuak tur niin ka ring." Mahse, dik tak chuan he hormone hi manipulate hi i ngaihtuah angin a awlsam lo.

Leptin hi eng nge thleng tak tak?

Leptin hnathawh ber chu i taksa rihna vawng reng tura puih hi a ni. Chu chu, i ei tur zat leh i taksain chakna a hman zat inkara hun rei tak chhunga inthlauhna siam turin a pui tihna a ni. Leptin hian riltamna a veng reng a ni. Tin, taksain chakna, a nih loh leh calorie a mamawh loh huna riltam signal lo thlengte pawh a control bawk .

Leptin hian i thluak hmun thenkhat hypothalamus an tih chu a nghawng nasa ber a ni . Hypothalamus hi riltam leh chakna hman dan control nana hmun pawimawh tak a ni. Mahse, taksa peng dangah pawh leptin receptor a awm bawk.

A pawimawh ber chu leptin hian chaw ei khat atanga chaw ei dang thlengin i riltam level a control mai lo. Chu ai chuan hun rei tak chhunga i ei leh in dan a thlak danglam a, i chakna hman dan a thunun a, i taksa rihna nghet tak i neih theih nan a pui bawk.

I taksa rihna tihtlem i tum hian leptin level a sang chho thin. Chu chu engtin nge a thawh? I taksain thau a tihtlem chuan leptin level a tlahniam thin. Hei hian i taksaah signal a thawn a, "Aw, ka ei tlem a, ka ril a tam hle mai," a ti. Hei hian riltamna nasa tak a thlen a, duhthusam a nei bawk. Hei hian i ei tur aia tam i ei tir thei a ni. Chuvangin a chang chuan taksa rihna tihtlem hi a harsa thei hle.

Scientist te chuan leptin hi an la zirchiang mek a ni. A nghawng bawk niin an ngai:

• I metabolism a ni
• Endocrine system, chu chu hormone system tihna a ni
• Immune system a ni

Engtin nge leptin level hi control a nih?

Leptin hi i taksaa white adipose tissue, a nih loh leh white fat cells atanga siam leh chhuah a ni. Heng white fat cells te hi kan taksaa thau chi khat ber an ni.

Leptin hi thau cell atanga lo chhuak a nih avangin i thisena leptin awm zat hi i taksaa thau awm zat nen a inzawm tlat a ni. A awlsam zawngin taksa thau i neih tlem chuan leptin i tlem zawk tihna a ni. Taksa thau i neih tam chuan leptin i nei tam zawk.

Hun kal zelah i taksa thau a san chuan leptin level a sang thin. Chumi kalh zawng chuan i taksa thau a tlahniam chuan leptin level a tlahniam bawk.

Leptin level a san chuan eng nge thleng ang?

Mi thau lutuk chuan an taksaah leptin a tam hle thei. Hei hi hyperleptinemia an ti a . Hetianga leptin a pun chuan taksain leptin a dawn lohna tur dinhmun a lo awm thei a ni. Hei hi leptin resistance an ti a .

Hyperleptinemia nena inzawm thei dinhmun dangte chu:

• Lungngaihna
• Chaw ei addiction
• Neurodegenerative natna (Neurodegenerative disorder) a awm thin
• Zu ni lo, thau thau natna ( NAFLD ) .
• Rabson-Mendenhall natna a ni

Leptin Resistance hi eng nge ni?

Leptin resistance i neih chuan i thluak hian leptin hi a pangngaiin a chhang lo. Leptin hian i thluak ah signal a thawn chhunzawm zel a nih pawhin "full" feeling i nei lo. Chuvang chuan i taksaah thau dahkhawmna tam tak nei mah la, i ei chhunzawm zel a ni.

Hetianga leptin tlakchhamna langsar tak avang hian i taksa chuan "riltam" i ni tih a ngaihtuah a ni. Energy humhalh nan i thluak hian i energy level a tihhniam a, chawlh laiin i calorie i hal zat pawh a ti tlem bawk. Hei hian i Basal Metabolic Rate (BMR) a tlahniam tihna a ni.

Chuvangin, leptin resistance hian riltam a ti reng a, i BMR pawh a tlahniam bawk. Hei hian taksa rihna a tizual a ni.

Tunah hian scientist-te chuan leptin resistance tidam thei damdawi siam chhuah an tum mek a ni.

Leptin do theihna chhinchhiahna

Leptin do theihna chhinchhiahna ber chu riltam reng reng, a nih loh leh hyperphagia , leh ei tur tam lutuk hi a ni. Heng symptoms te hi taksa thau tam lutuk i neih hian a awm a, thau tam lutuk pawh a ni thei.

Mahse, heng symptoms te hi thil dang tam tak avanga lo awm thei a ni a, leptin resistance chauh ni lovin. Scientist ten leptin chungchang an la zir zel avangin nakin lawkah leptin resistance symptoms tam zawk hmuhchhuah a ni thei.

Leptin Deficiency i neih chuan eng nge thleng?

Leptin tlakchhamna, hypoleptinemia tia hriat bawk hi thil awm lo tak a ni. Hemi nena inzawm ber chu congenital leptin deficiency a ni . Hei hi i pianpui genetic condition a ni. Hei hian i adipose tissue hian leptin a siam thei lo tihna a ni.

Leptin a bo chuan i taksa chuan taksaah thau a awm lo niin a ngai a. Chu chuan thunun theih loh riltam leh duhâmna a thlen a ni. Hemi avang hian naupang te te congenital leptin deficiency nei te hian class III obesity leh delayed puberty an nei thin.

Hetiang dinhmun hi natna dang engemaw zat nen pawh a inzawm a ni:

• Dyslipidemia (thau, cholesterol leh triglycerides te inthlauhna) .
• Fatty liver natna a ni
• Bacteria natna kai fo thin
• Hyperinsulinemia (insulin siam tam lutuk) .
• Hypogonadotropic hypogonadism (sex hormone level hniam) .

Engtin nge leptin level hi kan enfiah ang?

Thisen test hian i leptin level a enfiah thei a ni. Mahse, doctor-te hian mi zawng zawngah leptin level an check vek lo. Heng dinhmunah hian leptin test tih chauh an ngaihtuah thin:

• I fa te hian grade 3 obesity a neih chuan
• I thau lutuk a, riltam reng reng i nih chuan

Leptin level pangngai chu engte nge ni?

A tlangpuiin leptin level hi hetiang hi a ni thei:

• Hmeichhia tan: Milliliter khatah nanogram 0.5 atanga 15.2 ( 0.5 atanga 15.2 ng/mL ) .
• Mipa tan: Milliliter khatah nanogram 0.5 atanga 12.5 ( 0.5 atanga 12.5 ng/mL ) .

Mahse, heng normal value te hi lab hrang hrangah hian a danglam deuh thei a ni. Chuvangin, i test report-a normal range kha check ngei ngei tur a ni a, a nih loh leh i result chungchanga zawhna i neih chuan doctor zawt ngei ang che.

Engtin nge ka leptin level hi ka tihsan theih ang?

Dik tak chuan, riltam emaw, ei duhna emaw tihziaawmna turin leptin level tihsan nan hian tih theih tam tak a awm lo. Chu chu i leptin level hi i taksaa adipose tissue i neih zat nen a inzawm tlat vang a ni.

Zirchianna pakhatah chuan mut tam tawk lote hian ghrelin (the hunger hormone) an nei sang zawk a, leptin an nei tlem zawk tih hmuhchhuah a ni. Chuvangin, mut tam hian i hormone te chu a balance reng thei a ni.

Scientist te chuan leptin leh triglycerides te hi an inzawm tih an sawi(Hei hi thau chi khat lipids an tih pawh a ni). Zirna thenkhatah chuan triglyceride level a san chuan leptin hnathawh dan a nghawng tih hmuhchhuah a ni. Mahse heng zirchianna chungchangah hian ngaihdan hrang hrang a awm. Scientist thenkhat chuan triglycerides tihhniamna tura ruahman ei leh in hian leptin level a tisang thei niin an ngai a, mahse thenkhat chuan an pawm lo.

Eng ei tur nge leptin tamna?

Leptin hi i taksa siam hormone a ni a, vitamin C emaw protein ang chi nutrient a ni lo. Chuvangin eitur engmahin leptin a pai lo.

Leptin hi thil thar hmuhchhuah a nih avangin scientist-te chuan an la zir belh zel a, a bik takin thau lutuk leh taksa rihna tihtlem a nghawng dan hi an la zir belh zel a ni. I taksa thau a tlem chuan taksa rihna tihtlem a harsa thei a, a chhan chu leptin hian taksa "riltam" signal a tichak a ni.

Take-Home Thuchah a ni

Okay, chuvangin leptin chungchang kan sawi tawh atang khan hei hi i hre reng thei ang:

• Leptin hi i thau cell atanga hormone siam a ni a .
• Hemi chungchanga thil pawimawh ber chu hun rei tak chhunga i rihna control turin a pui a , "fullness" feeling a pe bawk .
• I taksa thau a san chuan leptin level a sang a , i taksa thau a tlahniam chuan leptin level a tlahniam bawk.
• Leptin resistance chu taksain leptin nei mahse thluak hian a chhanna mumal lo a nih chuan a ni. Hei hian taksa rihna a tipung thei a ni.
• Leptin tlakchhamna hi a tlem hle .
• Chaw engmahin leptin a pai lo, a chhan chu taksa chhunga siam chhuah a nih vang a ni.
• Nun hrisel, a bîk takin mut ṭhat , chuan hormone inthlauhna a ṭanpui thei a ni.

I taksa rihna i ngaihtuah emaw, hrisel taka i taksa rihna tihtlem dan tur thurawn i mamawh emaw a nih chuan i doctor nen inbia ang che. Hormone lama tui tak doctor, endocrinologist hnenah pawh i taksa rihna tihtlem dan tur i sawipui thei bawk. A pawimawh ber chu i hriselna enkawl hmasak hi a ni.

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