Kan nu leh pa leh upate an lo upat deuh deuh chuan an hriatrengna an hloh zauh zauh tih kan hmuh hian kan hlau deuh vek a. "Hei hi Alzheimer natna bul tanna a ni em?" Zawhna chu kan rilru hnung lamah a awm a. Tun thleng hian Alzheimer natna hi mi hriatrengna enfiah a, nungchang inthlak danglamna ang chi symptoms zawng chhuakin a hriat chhuah a ni tlangpui. Mahse tunah chuan khawvela damdawi lam thiam lar pawl pakhat chuan he system hi thlak danglam turin rawtna lian tak an rawn siam ta a ni. An sawi dan chuan, natna lan chhuah hun nghah ai chuan taksaa biological evidence hmangin he natna hi a lo awm hma hian kan hriat chian a ngai a ni, an ti.
Engvangin nge hetiang system thar hi a tul?
I ngaihtuah mai thei, "Engvangin nge he system hi thlak danglam? Tuna system hman mek hi thil dik lo a awm em?" Dik tak chuan tuna kan system hian thluaka chhiatna engemaw zat a awm hnuah leh a nghawng chu symptom anga a lan tan hnuah chauh natna hi a hmuchhuak thin. Chu chu diagnosis hmuh a tlai deuh tihna a ni.
Mahse hei hi he rawtna thar ngaihtuahna ber a ni.
Alzheimer natna hi biologically-a sawifiah tur a ni a, symptoms atanga sawifiah tur a ni lo.
A awlsam zawngin, detective-in thil sual a tih hmaa clues a zawn ang bawkin, a tum ber chu a natna lan chhuah hmaa taksaa inthlak danglamna hriatchhuah a, natna hriatchhuah a ni. A chhan chu, tun hnaia medical science lama hmasawnna avang hian hetiang biological clues hmuchhuak thei tur testing method thar siam a ni ta a ni. Hei hian damlote chu an dinhmun chu a hmain an hre thei a, chutiang chuan an nun chungchangah thutlukna an siam thei a, a tul anga enkawlna an zawng thuai thei bawk. Tin, a chang chuan Alzheimer natna ang chi natna dang pawh a awm thei bawk. He hmanraw thar avang hian doctor-te tan dik tak leh rang taka Alzheimer’s nge natna dang a nih leh nih loh hriat a awlsam phah hle.
Heng biomarker te hi engte nge ni?
" Biomarkers " tih thumal i hriat hian thumal lian tak, buaithlak tak niin i ngai mai thei. Mahse a takah chuan a awlsam khawp mai. Kan taksa hi motor angin han ngaihtuah teh. Car engine-a thil dik lo a awm tan chuan a chang chuan dashboard-ah warning light a rawn eng a, a dik em? Chutiang bawkin kan taksaah thil a kalsual tan chuan kan thisenah te, kan thluak tuiah te, a nih loh leh kan tissue dangah emaw a chhinchhiahna kan hmu thin. Chu chu biomarker kan tih chu a ni.
Alzheimer natna chungchang sawi dawn chuan biomarker lian pahnih a awm a.
1. Beta-amyloid proteins: Chungte chu thluaka an pung khawm a, clump te te (plaques) an siam thin.
2. Tau proteins: Hengte hi thluaka nerve cells chhungah an pungkhawm a, tangles an siam thin.
Tun thleng hian heng proteins awmna dik tak hriat theihna awmchhun chu thluak scan specialized (leh man to tak) hmangin a ni. Mahse tunah chuan thisen test thar siam chhuah a ni a, chu chuan awlsam takin heng proteins level hi a teh thei ta a ni. Hei hi he ruahmannaa hmasawnna lian ber a ni.
Cancer ang chi staging system a ni
Cancer chungchang hi i hre tawh ngei ang. Cancer hmuhchhuah a nih hnuah doctor-te chuan "Stage 1" leh "Stage 2" tih ang chi stage hrang hrangah an ṭhen ṭhin. Hei hian damlo leh enkawltu te chu natna nasat zia leh a darh zau zia chiang takin a hriattir a ni.
Tunah chuan heng mithiamte hian Alzheimer natna tan pawh hetiang staging system hi siam chhuah an rawt ta a ni. He system ang hian damlo chu stage 0 atanga 6-ah then a ni a, he classification hi a chunga kan sawi tak biomarker awm dan te, chubakah hriatrengna leh nungchang lama hriatna lama inthlak danglamna fiah lo tak takte atanga thlir a ni. Hei hian damlo leh chhungte chu natna stage-ah an awm tih chiang takin a hrethiam thei dawn a ni.
He phased system thar hian engtin nge hna a thawh?
He system ruahman hi sawiho a la ni a, mahse tuna a awm danah chuan stage hrang hrangte thliar hranna chu hetiang hi a ni.
| Dawhsan | A awmzia leh sawifiahna |
|---|---|
| Stage 0 ah a awm | Heng mite hian symptoms an nei lo va, biomarker an nei lo a, mahse nakin lawkah Alzheimer’s vei theihna chance sang zawka dah thei gene an nei (e.g., Down syndrome vei te). |
| Stage 1-na a ni | Heng mite hian symptoms an nei lo bawk . An hriatrengna a tha khawp mai. Mahse thisen test emaw scan emaw an tih laiin Alzheimer’s nena inzawm biomarker an nei tih an hmuchhuak. |
| Stage 2-na a ni | Biomarker te pawh a awm a, chubakah hriatrengna, nungchang leh ngaihtuahna te pawh a awm bawk.Hrilhfiahna fiah lo tak tak a awm tan ta. Hengte hian nitin hnathawhnaah nghawng lian tham a nei lo mai thei. |
| Stage 3-na a ni | Hei hi tuna "Mild Cognitive Impairment" kan tih nen hian a inang hle. Hriatrengna hloh ang chi symptoms te chu a langsar zual zel. |
| Stage 4, 5, 6-ah te a awm | Heng stage pathumte hi tuna kan sawi thin mild, moderate, leh severe dementia nen a inang a ni. Symptoms a lang chiang a, nitin hna thawh a harsa ta hle. |
Hetiang hmanrua hi a thatna leh harsatna a awm.
He hmanraw thar hian a thatna lian ber chu natna hi a hriat hma hle a ni . Chuvang chuan hetiang hun hmasa lama awmte hian enkawlna thar an hlawkpui ber thei a ni.
Mahse chona lian tak a awm a, inhnialna pawh a tam hle. Mi hrisel, theihnghilh leh chhinchhiahna nei lo, thisen test result en mai maia, "Alzheimer natna hmasa ber i nei" tih mai maia hrilh ta la, eng nge thleng ang? Chu chuan chu mi rilru hrisêlna te, an insurance policy te, leh an hnathawhna te chu engtin nge a nghawng ang? Hei hi damdawi lam mithiam thenkhat phei chuan zawhna an siam nasa hle. Chuvangin, chutiang diagnosis pek a nih chuan damlo hnenah thurawn dik tak pek a pawimawh hle a, chutih rual chuan a pawimawh hle. Hei hi mithiamte zingah sawihona a la awm reng a ni.
Mahse, he rawtna hian Alzheimer natna hmuhchhuah leh enkawlna kawngah hmasawnna lian tak kan nei dawn tih a tilang chiang hle.
Take-Home Thuchah a ni
- Mithiamte chuan Alzheimer natna hriat dan tur chu thisen leh scan-a biomarker hmuh chhuah atanga siam a ngai a, symptoms atanga chhut ai chuan a ni tur a ni, an ti.
- Hemi tum ber chu natna lan chhuah hmaa hriatchhuah a, a hmaa enkawl theihna hun remchang siamsak hi a ni.
- Cancer ang bawkin Alzheimer natna hi stage 0 atanga 6 thlenga staging system siam tura rawtna siam a ni.
- Miin symptoms nei lo, mahse biomarker a neih chuan "Alzheimer's Stage 1" tih hriat theih dan chungchangah hian mithiamte zingah ngaihdan hrang hrang a la awm.
- Heng zawng zawng hi proposal stage-ah a la awm laiin, nakin lawkah hman a nih chuan Alzheimer enkawlnaah danglamna nasa tak a thlen thei a ni. Nangmah emaw, i hnaih ber emaw hian hriatrengna lama harsatna i neih chuan i doctor nen inbiakna neih a pawimawh hle.
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