I nervous system-ah hian tumor hmuh tur awm lo tak i nei em? (Malignant Peripheral Nerve Sheath Tumor - MPNST) A chanchin hi i zir chiang ang u.

I taksa hmun dangah, i kut emaw, ke emaw-ah pawh ni se, zawi zawiin a lo lian chho zel tih i hre ngai em? Heng lumps te hi a chang chuan pea ang maia te atanga intan thei a, orange ang maia lian thei te hi vawiinah hian kan sawi dawn a ni. Hei hi natna pawi tak a ni a, mahse a tlem hle. Malignant peripheral nerve sheath tumor an ti a, a tawi zawngin MPNST an ti bawk.

Malignant peripheral nerve sheath tumor (MPNST) tih hi eng nge ni?

A awlsam zawngin sawi ila, MPNST (Malignant Peripheral Nerve Sheath Tumor) hi cancer natna hlauhawm tak a ni a, i taksa chhunga nerve vel venhimna khuhna (nerve sheaths)-ah a lo awm thin. Hengte hi soft tissue sarcoma chi khata mi an ni . I peripheral nervous system ah an lo chhuak thin . Ngaihtuah teh, heng tumor te hi i kut leh keah i nei thei a ni. Chu mai ni lovin, a chang chuan pelvis, abdomen, lu, leh neck-ah te pawh an lo thang lian thei bawk. Heng tumor te hi surgery hmanga lakchhuah a tihdam theih a ni. Mahse, a châng chuan heng tumor te hi a lo lang leh thei tih kan hriat reng a ngai bawk .

MPNST hi engtiang chiahin nge a tlem?

Hei hi thil awmdan tlemte tak a ni. Kum tin mi 100,000 zinga pakhat vel chauhvin he malignant peripheral nerve sheath tumor (MPNST) hi an vei tih hmuhchhuah a ni. Kum 30 leh 50 inkar te a vei tlangpui .

Tin, Neurofibromatosis type 1 (NF1) tih hming pu genetic condition nei te hian MPNST an vei tam zawk bawk. MPNST vei zinga 25% leh 50% inkar pawhin NF1 an nei tih hmuhchhuah a ni bawk.

A tlangpuiin NF1 nei lote aiin NF1 vei zingah MPNST hi a lo awm hma zawk thei. Tin, NF1 nei mipa te hi NF1 nei lo te aiin MPNST an vei tam zawk deuh bawk.

MPNST natna lan chhuah dante chu engte nge ni?

MPNST hi i peripheral nerve-ah khawi hmunah pawh a lo awm thei a, mahse i kut leh ke ang chi hmun a nghawng tam ber. A châng chuan i pelvis, i rilru, i pum, emaw lu leh kawr ang chi hmunah pawh an lo awm thei bawk. MPNSTs natna lan chhuah dan chu:

• Vun hnuaia zawi zawiin a lo thang lian thin lump. Heng lumps te hi pea ang maia te (centimetre 2 vel) emaw, orange ang maia lian (centimetre 10 vel) emaw pawh a ni thei.
• Natna hriat (a bik takin NF1 i neih chuan).
• A rilru a buai em em (Paresthesia).
• Kut leh kea chak lohna hriatna.

MPNST awm chhante chu engte nge ni?

Zirna hrang hrangah chuan malignant peripheral nerve sheath tumor zinga 50% chu neurofibromatosis type 1 (NF1) vang a ni tih hmuhchhuah a ni.Condition chu koh a ni. A chhan dangte chu:

• Radiation therapy: MPNST vei zinga 10% velin natna dang atan radiation therapy an dawng tawh a ni.
• Genetic mutations: Zirchiangtute chuan genetic mutations hrang hrang engemaw zat a awm tih an hmuchhuak a, chu chuan nerve sheath cell pangngai chu cell pangngai lo takah a chang a, a pung a, tumor a siam a ni.
• Neurofibroma chi thenkhat: Plexiform neurofibroma vei te hi MPNST vei theihna a sang hle.

Engtin nge MPNST hi hmuhchhuah a nih?

Doctor i hmuh hunah chuan taksa enfiahna a nei hmasa ang a, i hriselna tlangpui a zawt ang. Hei hian i damdawi lam chanchin, chhungkaw damdawi lam chanchin, leh i natna lan chhuah dan eng pawh zawh a huam ang. Chu bâkah, a hnuaia mite hi an ti thei bawk:

• Imaging test: Doctor-te chuan MRI (Magnetic Resonance Imaging) leh PET (Positron Emission Tomography) scan ang chi test an ti thei a ni .
• Biopsy: Doctor chuan biopsy a ti thei a, tissue sample a la thei a, microscope hmangin pathologist hnenah a enfiah thei a ni .
• Genetic tests: Malignant peripheral nerve sheath tumor i neih chuan i doctor chuan nangmah emaw, i chhungte hnai tak emaw neurofibromatosis type 1 (NF1) emaw, nerve sheath tumor chi dang , neurofibromatosis type 2 (Schwannomatosis) emaw an neih leh neih loh enfiah turin genetic test neih a rawt thei ang.

MPNST enkawlna tur engte nge ni?

Doctor-te chuan malignant peripheral nerve sheath tumor tihbo nan surgery an nei tlangpui. Mahse, zai theih lohna hmun thenkhat a awm. Entir nan:

• Nut lian tak tak (nut 5 cm aia lian).
• Metastatic tumor a awm thin.
• Complex nerve network hnaih takah awm tumor te chu operation neih laiin a chhe thei a ni.

Hetiang hunah hian doctor-te chuan MPNST chu surgery, chemotherapy , emaw radiation therapy hmangin an enkawl thei a ni. Radiation therapy hi operation hma emaw, operation hnuah emaw pek theih a ni.

Tunah chuan zirchiangtute chuan immunotherapy emaw targeted therapy emaw chu enkawlna thar atan hman theih a nih leh nih loh an enfiah mek a ni. Malignant peripheral nerve sheath tumor i neih chuan enkawlna thar test-na clinical trial-ah i tling thei ang.I doctor nena tel tur chungchang sawipui chu a tha mai thei.

Enkawlna avanga harsatna emaw, nghawng tha lo emaw awm thei te chu engte nge ni?

Surgery neih chhunga harsatna awm thei te chu:

• General anesthesia hmanga chhanna.
• Thisen chhuah tam lutuk (thisen chhuak).
• Na.
• Surgery hmanga hliam a awm.
• Surgery hmanga hliam natna hrik kai.

Chemotherapy emaw radiation therapy emaw ang chi enkawlna hian side effect a thlen thei a, chungte chu:

• Kawthalo.
• Chau.
• Nausea leh luak chhuak.

MPNST vei tan chuan eng prognosis nge a awm?

Prognosis chu i medical team-in enkawlna i zawh hnua i awm dan tur anga an ngaih a ni. MPNST-ah chuan he prognosis hi thil engemaw zatin a hril a:

• NF1 dinhmun: NF1 vei te zingah heng tumor te hi an lo awm chuan NF1 nei lo te aiin an dam leh theihna tur prognosis a hniam deuh thei.
• Tumor grade: Pathologist-te chuan microscope hmangin cell-te chu an en a, tumor chu high-grade emaw low-grade emaw tiin an classified a. High-grade tumor te hian cancer cells an neih theihna chance a sang zawk a, chu chu rang takin a inthen darh a, a darh zel bawk.
• Tumor size: MPNST tumor hi centimetre 10 vel a lian thei a ni. Tumor lian tak takte hi surgery hmanga lakchhuah a harsa tlangpui.
• Metastasis: Tumor hi a bul atanga hmun dangah a darh tawh a nih chuan enkawl a harsa thei hle.

I hmuh angin, i dam leh theihna tur tichhe thei thil tam tak a awm a, heng zawng zawng hi i tan a hman theih vek lo mai thei. Chuvangin i dinhmun chipchiar tak tak doctor hnenah zawt la a tha ber. I dinhmun a hriat avângin, i mamawh thu hriattîrna chu a pe thei che a ni.

MPNST damchhuah zat chu engzat nge ni?

Survival rates hi midang malignant peripheral nerve sheath tumor nei tawhte thil tawn atanga chhut a ni. Heng tumor te hi a tlem em avangin mithiamte tan chuan rate dik tak sawi a harsa hle. National Cancer Institute (US) chhinchhiah danin, MPNST vei zinga 23% leh 69% inkar chu an hmuhchhuah atanga kum nga hnuah an dam tawh a ni. Chu chu range lian tak a ni lawm ni? Chuvangin i dinhmun hi doctor zawt la a tha ber.

Engtin nge ka in enkawl ang?

Malignant peripheral nerve sheath tumor i neih chuan cancer hmuh tur awm lo tak i hmachhawn a, enkawl hnuah a lo kir leh thei a ni. Hetiang dinhmunah hian program engemaw zat a awm a, chungte chu:

• Palliative care-a enkawlna: 1.1.Palliative care-ah chuan MPNST symptoms leh enkawlna avanga side effects te enkawl tura pui thei tur doctor specially trained team nen in thawk ho ang. Chubakah, psychological support an pe bawk ang che.
• Cancer damchhuahna programme: Cancer hi zinkawng ang a ni. Cancer damchhuahna programme te hian i hmuhchhuah ni atang te, i enkawl dan te, cancer a lo let leh a nih chuan eng nge i tih tur tih te a kaihruai che a ni.

A hmasa berah chuan i kut emaw ke emaw-a malignant peripheral nerve sheath tumor (MPNST) awm chu awlsam taka hliam emaw, hliam emaw i neih theihna tur zungbun ang maiin a lang thei. Lump hi cancer chi khat hmuh tur awm lo tak a nih thu leh operation a ngai tih hriat chu thil mak tak a ni thei. It can be hard to take in. I dinhmun emaw, beisei tur emaw chungchanga zawhna i neih chuan i medical team chuan an hrethiam. I zawhnate chhân nân hun an hmang ang a, i ngaihtuahna eng pawh chu an ngaihtuahsak ang.

He thuziak atanga take-home message hi

Okay, chuvangin vawiin a kan sawi tawh, he cancer natna hmuh tur awm lo MPNST tih hi hriatthiamna engemaw chen in neih ka beisei. Hei hi thil awm lo tak a ni tih hre reng ang che. I taksaah hian lumps, natna, numbness, etc. danglam tak tak, a awm reng a nih chuan doctor pan ngei ngei tur a ni a, thurawn la rawh. A hriat hma poh leh enkawl a awlsam zawk.

A pawimawh ber chu nangmah chauh i ni lo. I medical team, chhungte leh i thiante chu tanpui turin an awm vek a ni. A pawimawh ber chu chak taka awm a, doctor thurawn zawm hi a ni.

` Malignant peripheral nerve sheath tumor, MPNST, nerve cancer, tumor, cancer, neurofibromatosis, NF1, surgery, radiation therapy, chemotherapy te a awm bawk