Odevixibat (Bylvay) - PFIC natna vei naupang vun na tak tan damdawi pek dan i zir dawn nia

I fate hian PFIC (Progressive Familial Intrahepatic Cholestasis) tih hming pu liver condition a nei a nih chuan a taksa a hrual reng tih i hre tawh ngei ang. A chang chuan a muhil thei lo a, a taksa chu a vun a hrual thlengin a hrual thin. Hei hi naupang tan pawh nu leh pa tan pawh thil hrehawm leh lungngaihthlak tak a ni. Chuvangin, he vun natna tuar theih loh hi control nana doctor-te’n damdawi bik an rawt chu Odevixibat (brand name Bylway) a ni. Vawiin hian he damdawi hi kan sawi dawn a, i fa hnena pek dan tur leh fimkhur tur thilte kan sawi dawn a ni.

Odevixibat hi eng damdawi nge ni?

A awlsam zawngin sawi ila, Odevixibat hi damdawi chi khat , Ileal Bile Acid Transporter (IBAT) Inhibitors -a tel a ni. Hetiang hian han ngaihtuah teh: kan liver-in a siam chhuah tui, ei tur ei tura puitu bile acids chu kan intestin-ah a lut leh thin. PFIC ang dinhmunah chuan he bile hi taksaah a pungkhawm a, tuar theih loh khawpa natna a thlen thin.

Chuvangin he Odevixibat damdawi hian a tih chu bile chu intestines atanga taksaa a luh leh theih loh nan a titawp a ni. Tichuan taksaa bile extra chu bawlhhlawh nen a chhuak ta a ni. Hetiang a nih avang hian PFIC natna nena lo awm tuar theih loh vun natna (pruritus) chu nasa takin a tlahniam a, naupang chu hahdamna nasa tak a pe a ni.

Damdawi ei tan hmaa doctor hnena hrilh tur pawimawh ber berte

I fate hnena Odevixibat i pek hmain i doctor hnenah he thu hi i hrilh hmasak phawt a pawimawh. Hei hi i fate himna atan a pawimawh hle.

Engtin nge he damdawi hi naupang hnenah i pek ang?

Hei hi a pawimawh hle a ni. Damdawi pek dan dik tak hrethiam rawh.

• He damdawi hi capsule angin a awm a, mahse a pum puia ei tur a ni lo .
• Nitin i damdawi chu hun khatah ei thin tur a ni tih hre reng ang che , i doctor-in a tih angin. A tlangpuiin, chaw ei rualin zing lamah ei a tha.
• Step 1: Fimkhur takin capsule chu hawng rawh. Pellets chu a chhungah chuan chaw nêm tablespoon khat emaw pahnih emaw chhungah dah la. Entirnan, yogurt, mashed banana emaw, applesauce emaw i hmang thei.
• Step 2: Damdawi leh chaw chu a inhmeh tawh chuan naupang chu ei tir rawh. Naupang chu tablet emaw, a chawhmeh emaw chu ei tir ngai suh.
• Step 3: He damdawi hi tui, bawnghnute, in tur te nen eng chhan pawh nise pawlh loh tur.
• Pawimawh: I fain damdawi dang (bile acid binding resins) Cholestyramine emaw Colesevelam emaw a ei a nih chuan Odevixibat hi a ei hma darkar 4 emaw, darkar 4 hnuah emaw pek tur a ni. I doctor hnenah thupek chiang tak zawt rawh.
• I doctor-in a tih hma loh chuan damdawi ei kha bansan suh. He damdawi hi nangmah tan chauh pek a ni a, midang hnenah pe chhuak suh.

Dose i miss a nih chuan lungngai suh. I hriatreng veleh missed dose kha ei nghal rawh. Mahse, i dose leh tur hun a lo thleng tawh a nih chuan missed dose kha skip la, a hnuaia dose chu a hun ruatah ei rawh. Double dose ei ngai suh.

Damdawi ei huna fimkhur tur thil

• Doctor hmu fo rawh: Ni ruat saah doctor i hmu tur a ni a, i fa awm dan leh damdawi hian hna a thawk em tih i enfiah tur a ni.
• Thisen Test: He damdawi hi i ei lai hian i fain thisen test a neih a ngai dawn a, a liver function leh vitamin level te a enfiah a ngai dawn a ni.
• Vitamins leh Nutrition: I fain a mamawh vitamin (a bik takin A, D, E, leh K) a dawng tih chian a pawimawh. I fa doctor hnenah i fate ei leh in chungchang leh vitamin dang a awm chuan sawipui rawh.

Damdawi i ei tam lutuk chuan engtin nge i tih ang? (Overdose) a ni.

I fa chu i ngaihtuah aia tam damdawi pek a nih thu rinhlelhna tlemte i neih chuan hun khawhral suh la , Colombo National Hospital-a National Poisons Information Center-ah phone nghal rawh. A nih loh leh, i fa chu damdawi in hnai ber Emergency Treatment Unit (ETU)-ah hruai la.

Side effect awm thei te chu engte nge ni?

Damdawi zawng zawng ang bawkin he damdawi hian side effect a nei thei a ni. Mi zawng zawngin kan hmu vek lo a, mahse fimkhur a pawimawh.