I fa hian heng chhinchhiahna mak tak takte hi a nei em? Naupan laia multiple sclerosis (MS) chungchang hi i zir dawn teh ang!

I naupang tê hian kal a harsat thut mai em? A nih loh leh an mit hmuh chu a fiah lo nge a fiah lo em ni? A châng chuan hengte hi thil tenawm tak tak lo chhuak mai mai a ni thei. Mahse, a tlem berah chuan heng symptoms te hi kan sawi vak loh natna chhinchhiahna hmasa ber a ni thei a, mahse fimkhur a pawimawh hle. Vawiin hian chutiang natna pakhat, `Multiple Sclerosis` emaw `MS` tih chu kan sawi dawn a, chu chuan naupang kum 18 hnuai lam a vei a, lungngai suh, hei hi awlsam takin, i hriatthiam theih angin kan sawi dawn a ni.

Heng naupangte hian ``multiple sclerosis (MS)'' an neih hi eng nge ni?

A awlsam zawngin sawi ila, hei hi immune system a tha lo vanga lo awm natna a ni. Kan taksa invenna (immune system) hi ram venghimtu sipai ang a ni. A hna chu pawn lam atanga hrik leh natna lo chhuakte do a, kan taksa venhim hi a ni. Mahse, naupang `MS` veiah chuan he immune system hian tihsual tlemte a nei a ni. A taksa cell hrisel tak takte chu a bei tan ta a ni.

A dik tak chuan he attack hian naupang Central Nervous System a target a ni. Chu chu thluak leh ruhro (spinal cord) tihna a ni. Thluak leh ruhro chhunga nerve te hian electric wire vel plastic sheath ang maia venhimna khuh an nei a. Hei hi covering hi ``Myelin'' kan ti a ni.``Myelin'' tih hi message te chu nerve kaltlangin rang tak leh awlsam taka kal theihna tur a ni.

MS-ah chuan immune system hian heng myelin cells te hi a bei a, a tichhia a ni. Electrical wire sheath chu hmun thenkhatah an tan ang mai a ni. Hei hian thluak atanga taksa peng dang panna nerve message te chu a block emaw, a tibuai emaw a ni.

Hetianga myelin chhiatna hian taksa ruh chak lohna, hahna, hriatrengna hloh, kal harsa, leh mit hmuh dan inthlak danglamna te a thlen thin.

Ngaihtuah teh, i fa hian thianpa pakhat Nilanthi a nei a. Nilanthi chuan mit pakhatah natna a nei tan nghal a, a mit a ti tlahniam bawk. Doctor hnena a entir chauhvin MS chhinchhiahna hmasa ber a ni thei tih a hre ta a ni.

Tunah hian MS hi damdawi a la awm lo. Amaherawhchu, natna lan chhuah dan thunun tur leh natna avanga hun rei tak chhunga rualbanlote tihziaawmna tur enkawlna tha tak tak a awm a ni. Chuvangin lungkham a ngai lo.

Naupangte zingah MS chi hrang hrang eng nge lo awm?

Naupang MS chi khat awm tam ber chu ``Relapsing-Remitting MS (RRMS) .`` Naupang 98% velin he chi hi an vei a ni. Chutiang a nih chuan symptoms chu a lo lang nghal (flare-up/relapse), rei vak lo a awm a, a tlahniam emaw, a bo vek emaw (remission). Hun engemaw chen hnuah an rawn let leh mai thei. Chutiang chuan naupang dam chhung zawngin natna lanchhuahna chu a lo thleng a, a kal zel bawk.

A chi dang chu `Primary Progressive MS (PPMS)` a ni.Hei hi naupangte zingah a tlem hle. Thil thleng chu hun kal zelah a symptoms te chu a na zual sauh sauh thin. Symptoms tlahniam hi a tlem hle.

Naupangte zingah MS natna lan chhuah hmasak berte chu engte nge ni?

MS an hmuhchhuah hian doctor-te chuan heng chhinchhiahna hmasa berte hi an ngaihven hle a ni:

• Optic Neuritis: Hei hi mit pakhat emaw, mit pahnih emawa natna thlentu a ni a, chubakah mitdelna a awm bawk. A bik takin mit chhunga optic nerve chu a inflamed ta a ni. Naupang thenkhat chuan an rawng hmuh danah pawh inthlak danglamna an nei thei bawk.
• Transverse Myelitis: Hei hi ruhro hmun thenkhata inflammation awmin scarring a siam a, nerve signals a block a ni. Hei hian taksa peng hrang hrang chak lohna, rilru hahna, leh kal theih lohna ang chi symptoms a thlen thei a ni.

Ngaihtuah teh, i fa, a hming chu Kavindu ti ila. Ni khat chu Kavindu chu sikul atanga a lo haw chuan, "Nu, ka ke chu a hlim hmel hle mai," a ti a. Rei vak lo a liam hnu chuan kea kal a harsat phah ta a. Hei hi Transverse Myelitis vang pawh a ni thei.

Naupangte zingah MS natna lan chhuah dan tlangpui engte nge ni?

MS natna lan chhuah dan hi mi hrang hrangah a inang lo thei. Naupang pakhatah pawh nitin symptom a inang lo thei. Mi zawng zawng hian heng symptoms zawng zawng hi an nei vek dawn lo va, mahse a tlangpuiin tlemte chauh hmuh tur a awm ang.

• Numbness, tingling (paresthesia) : Hetiang hriatna hi kut, ke, leh hmaiah te a awm thei.
• Luak chhuak thei
• Kal harsa emaw, balance vawn emaw
• Chauhna: Hei hi hahna pangngai mai a ni lo. Eng ang pawhin muthilh mah ila chau ang maia inhriatna a ni.
• Muscle chak lohna
• Tremors/a nghing
• Concentration emaw memory emaw lama harsatna
• Vision issues: mit hmuhna (blurry vision) emaw, mit hmuhna pahnih (double vision) ang chi.

Heng symptoms pakhat emaw pahnih emaw i neih vang mai mai hian MS a ni tih ngaihtuah suh. Mahse, heng symptoms te hi a la awm reng emaw, i fain harsatna a neih chuan doctor thurawn lak a pawimawh hle.

Eng thilin nge naupangte MS vei chhan?

MS natna thlentu ber chu demyelination a ni . A hmain myelin sheath chungchang kan sawi tawh a. Demyelination hi myelin sheath tihchhiatna a ni.

Kan naute immune system hian eng emaw chhan vangin he peng hrisel tak `Myelin` an tih hi taksa tana chhiatna thlen thei thilah a ngai sual a ni. Tichuan a rawn bei tan ta a ni. He beihna hian `Myelin` a tichhia a ni. Heng hmun chhiaah hian hliam (doctor-te chuan `lesions` emaw `plaques` an ti bawk) a lo awm thei a ni. Heng hliamte hi `MRI (Magnetic Resonance Imaging)` ang chi scan hmanga hmuh theih a ni.

Myelin a chhiat chuan thluak atanga taksa peng hrang hranga thuchah thehdarh chu a tibuai thin. Chu chu MS natna lanchhuahna thlentu a ni.

Researcher-te chuan immune system hian hetiang hian a nungchang dik lo chhan chiang takin an la hre lo.

Naupang MS vei theihna tur risk factors te chu engte nge ni?

Naupai laiin nu tichhe thei thil thenkhat chuan a fain MS a vei theihna a tipung thei tih hmuhchhuah a ni:

• Toxin-a inhriatthiamna: Entirnan, secondhand smoke, pesticides, etc.-a inhnamhnawih.
• Thisenah Vitamin D a tlem.
• Viral infection thenkhat nena inzawmna: Entirnan, Epstein-Barr virus emaw mononucleosis (kissing disease tia hriat bawk) emaw.
• Thau lutuk.

Chuvangin naupai lai hian hrisel taka awm a pawimawh hle. Damdawi lam thurawn zawm hian heng hlauhawmnate hi a tihziaawm thei a ni.

Naupang MS natna avanga harsatna awm thei te chu engte nge ni?

Naupangte hian MS vang hian harsatna engemaw zat an nei thei a ni. Hengte hi a lang nghal lo fo va, puitlin an nih veleh chauh a nghawng thei bawk.

• Ṭanpuina tel lova kal harsa.
• Depression leh Lungkhamna.
• Sikul hna thawh harsat.
• Kut inzawmna tha lo.
• Zun emaw ek emaw control harsa (incontinence).

Heng zawng zawng hian naupang zawng zawng a nghawng vek lo a, mahse a tul chuan tanpuina i hmuh thuai theih nan heng thilte hi hriat chian a pawimawh hle.

Doctor ten naupang MS hi engtin nge an hriat theih?

Doctor chuan naupang pakhat chu taksa enfiahna, thluak lam enfiahna, leh specialized test dang engemaw zât hmangin MS a vei tih a hriat theih . Heng test neih chhung hian doctor chuan i fate natna lan chhuah dan leh i chhungte zingah he natna hi an vei tawh em tih te a zawt ang che.

Diagnostic test hian MS nena inmil symptom nei natna dangte pawh a paih chhuak thei bawk. Heng test hrang hrangte hi:

• Thisen test leh zun test.
• Imaging test MRI (Magnetic Resonance Imaging) scan (mit nerve enna test pawh a awm a, Optical Coherence Tomography ang chi te pawh a awm bawk).
• Lumbar Puncture tih hi: 1.1.Hei hian spinal cord chhehvela tui thenkhat chu lak a, enfiah a ni.
• Evoked Potential (EP) Test: Hei hian nerve hmanga thuchah kal chak dan a teh a ni.

MS natna lan chhuah dan hi natna dang tam tak nen a inang avangin a dinhmun dik tak hriat theih nan hun engemaw chen a ngai thei a ni. Hei hi nu leh pate tan chuan a buaithlak deuh thei a, doctor pan vawi tam tak a ngai thei bawk. Mahse, diagnosis dik tak siam a nih hnuah chuan i fate chu uluk taka enkawl theih a ni a, naupan lai hlim tak, buaina awm lo zawk nei tura tanpui theih a ni bawk.

Naupang tê tête hian `MS` hi an hre thei em?

MS natna lan chhuah dan hi pian tirh lamah hmuh tur a awm lo. Chuvang chuan nausen pakhatin MS a vei a nih a rinawm loh hle. Naupang a lo puitlin chuan a natna lan chhuah dan chu a lang chiang hle. He natna hi puitlin lai hian a intan fo thin. A tam zawkah chuan kum 16 an tlin hmain natna hi hmuhchhuah a ni.

Naupang MS hi engtin nge enkawl a nih?

Naupangte zingah a awm fo thin, relapsing-remitting MS (RRMS) enkawlna ber chu disease-modifying therapy (DMT) a ni. Heng DMT damdawi te hian natna kal zel dan a thunun a, a lan chhuah tam dan pawh a ti tlem bawk. FDA (Food and Drug Administration)-in a pawmpui damdawi pakhat chu fingolimod tih pill a ni. Naupang kum 10 chunglam tan a tha. Tunah hian DMT dangte chu naupangte tana hman theih turin zirchian mek a ni.

Hei bakah hian doctor-te pawhin naupang natna lan chhuah dan bikte chu an enkawl bawk. Chûng zîngah chuan:

• Occupational Therapy: Nitin hnathawhnaah a pui thin.
• Physical Therapy: Taksa chakna leh inthlauhna siam turin a pui.
• Speech Therapy: Thusawi emaw, ei harsa emaw i neih chuan.
• Neuropsychological test leh enkawlna: Hriatrengna, ngaihvenna, leh zirlai ang chi thilte a pui thin.

Natna hian naupang hriatrengna leh ngaihtuahna (cognitive function) a nghawng a nih chuan sikulah tanpuina dang a ngai mai thei.

Damdawi thar enchhinna clinical trial -ah pawh tel theihna hun i nei thei bawk. Hemi chungchang hi i doctor chuan a hrilh belh ang che.

Engtikah nge ka fa doctor ka hmuh ang?

I fain a rilru a buai emaw, a mit a danglam emaw, a lan dan danglam tak emaw a hrilh che a nih chuan i fa doctor nen inbiakna neih nghal a pawimawh. MS hi a hmaa hriatchhuah a tha ber. Doctor-te chuan i fa chu an enfiah thei a, natna hriat theihna tura hmalakna ṭha ber chu an ruat thei a ni.

Natna hriat chhuah a nih hnuah, natna lan chhuah dan thar a lo lang emaw, a natna a zual thut (flare-up) a nih chuan nang emaw, i fa emaw chuan medical team hnenah hriattir tur a ni.

Naupan laia MS vei naupangte hmalam hun chu eng nge ni?

Naupang MS vei nia hriatte hian a tlangpuiin hmalam hun thlirna tha tak an nei thei a ni. A lan chhuah tam dan leh a nasat dan tihziaawmna tur enkawlna a awm bawk. Hun rei tak chhung chak lohna laka inven nan chuan dam chhung zawngin natna hi enkawl a ngai a ni. I fa hian a dam chhungin an MS medical team te nen an inhmuh fo a ngai dawn a ni.

Naupang relapsing-remitting MS (RRMS) vei thenkhat chuan puitling an nih chuan secondary progressive MS (SPMS) an tih natna an nei thei a. Hei hi symptoms a zual zauh zauh lai a ni. Mahse, zirchianna atanga a lan dan chuan naupan laia MS vei nia hriatte chu puitling laia SPMS vei te aiin natna a zual chak zawk tih hmuhchhuah a ni.

MS hian ka fa sikul nun a nghawng dawn em?

MS hian naupang hriatrengna leh ngaihtuahna (cognitive function) a nghawng theih avangin naupang chuan sikul hnathawhnaah harsatna a tawk thei a ni. Chuvangin neuropsychological test vawi khat tal neih a tha. Chumi hnuah chuan naupang zirtirtute nena inbiakna neih reng a pawimawh. Naupang chu anmahni duhthusam leh an zirna thil tum lam pan tura hmalam pan turin tanpuina i hmu thei ang.

MS vei naupang tam tak chu an kum rualpui naupang dangte nen an inrem tha hle. Naupang dang ang bawkin an khel thei a, thiltih hrang hrangah pawh an tel thei bawk.

Zawhna i neih chuan doctor chuan thiltih thenkhat chu naute tan a him em tih a hrilh ang che.

Nu leh pa i nih angin i fain MS a vei tih i hriat chuan i lungngai hle mai thei. Chu chu thil pangngai a ni. Mahse, naupangte MS vei tam zawk hi chu relapsing-remitting (RRMS) an ni tih hre reng ang che. Chumi awmzia chu symptoms a lo thleng a, a kal zel tihna a ni. Doctor chuan natna lan chhuah tam dan leh a nasat dan tihziaawmna turin enkawlna ruahmanna a siam thei a ni. MS hi dam chhung zawnga natna damdawi awm lo ni mah se, enkawl ṭhat a nih chuan i fa chu tihtawp tlem zawkin inkhelh leh zir turin i ṭanpui thei a ni.

Take-Home Thuchah a ni

• Naupang MS hi immune system-in nervous system-a myelin a beih thinna a ni.
• A lan chhuah dan a inang lo va, mit hmuhna lama harsatna, rilru hahna, kal harsa, leh hahna te pawh a tel thei.
• He natna hi a hmaa hriatchhuah leh `DMT` ang chi enkawlna hmanga control theih a ni.
• Naupang chuan sikul leh nitin nunah puihna dang a mamawh mai thei a, mahse naupang tam zawk chuan nun pangngai an hmang thei a ni.
• I fain natna lan chhuah dan danglam tak a neih chuan doctor thurawn la nghal rawh. Hlauthawng suh, thu leh hla dik leh puihna i neih chuan he dinhmun hi i tuar thei a ni.

`Naupan laia MS, Multiple Sclerosis, Nervous System, Myelin, Immune System, A natna lan chhuah dan, Enkawl dan