I thisena thisen sen (red blood cells) te hi an pianzia a danglam em? (Poikilocytosis) chungchang hi han sawi ila!

A châng chuan chhan awm lovin i chau a, i chau bawk em? A nih loh leh doctor-in i thisen test report a en a, "I thisen sen (red blood cells) pianzia a danglam deuh a?" Chutiang hunah chuan thumal kan hriat zinga pakhat chu `(Poikilocytosis)` (a lam tur: poi-ki-lo-say-to-sis) a ni. He hming i hriat hian hlau lutuk suh. Hei hi natna a ni lova, kan taksa chhungah thil dang a awm tih chhinchhiahna a ni thei. Chuvangin, hei hi hriat chian a pawimawh hle.

`(Poikilocytosis)` tih hi eng nge ni tak tak?

A awlsam zawngin ``Poikilocytosis`` tih hian kan thisena thisen sen (red blood cells) tam tak (chu chu 10% aia tam) chu a pianzia danglam tak a ni tihna a ni. Tunah chuan, "Chuti a nih chuan engvangin nge thisen sen (red blood cells) pianzia hi a pawimawh?"

Ngaihtuah teh, kan taksa chhunga cell, tissue leh organ dang zawng zawng hian nung leh hnathawh theihna turin chakna an mamawh vek a ni. Chu chakna chu oxygen-in a pe a ni. Tuin nge hria ang, he oxygen hi gas cylinder in lama hruai ang mai hian taksa pum puiah a phur lut vek a ni? Chu chu kan thisen sen (red blood cells) a ni. A tlangpuiin thisen sen hrisel tak i ei chuan an lian leh te, an pianzia inang vek an ni. Pawisa zungbun (disk ang chi) a sir lehlamah a hrual deuh ang mai.

Chuvangin, heng thisen sen hringte pianzia a inthlak (`(Poikilocytosis)`) emaw, a lian leh te a inthlak (`(Anisocytosis)` tih hming pu dang a awm) emaw chuan oxygen an phur tha thei lo. Chu chu anemia (thisen chhunga thisen awm lohna) ang chi condition kan neih hun a ni. Chumi awmzia chu taksa cell-te hian oxygen an hmu tling lo tihna a ni a, chu chu chakna tihna a ni.

Thisen sen (red blood cells) pianzia dik lo chu engte nge ni? (Poikilocytes) te hi a awm a.

Doctor-te chuan heng thisen sen hring (`Poikilocytes` tia koh bawk) te hi an pianzia a\angin an thliar hrang \hin. Thisen sample-a `(Poikilocytosis)` i neih chuan a hnuaia mi pakhat emaw a aia tam emaw i hmu thei ang:

• Acanthocytes / Spur cells : Hengte hi hling hnah ang mai an ni. Cell membrane atanga chhuak, spike ang chi protrusions sei tak, zau tak tak an nei a.
• Codocytes / Target cells : Hengte hi target board ang maia lang. A laiah chuan dark circle a awm a.
• Dacrocytes / Mittui tla cell : Mittui tla ang chi. Cell sir khat chu a hring a, a hrual bawk.
• Drepanocytes / Sickle cells : Hei hi cell te tak te, sickle ang maia lian, sickle cell natna vei te zingah hmuh theih a ni.
• Echinocytes : Tuipui urchin ang bawkin a cell hi a chhung zawngah a hlat zawng inang vek, ruhroin a khuh a.
• Elliptocytes / Ovalocytes emaw Cigar cells : Hengte hi oval ang maia sei leh sei danglam tak an ni. Egg ang atanga cigar ang thlengin an lian thei hle.
• Schistocytes : Hei hi thisen zam (red blood cells) chi hrang hrang (fragments) a ni. An hmel chu rough, broken appearance an nei fo a, mahse eng ang chi pawh an ni thei.
• Spherocytes: A zungpui (Spherocyte) a ni. Ball te tak te ang maiin.

Heng chi hrang hrangte hi damdawi lam dinhmun bik nen a inzawm thei a ni.

Hetiang natna lan chhuah dan hi engte nge ni?

``Poikilocytosis`` natna lan chhuah dan hi a chhan a zirin a inang lo. Amaherawhchu, a lan chhuah fo te hi thisen tlakchham vanga a lan chhuah dan nen a inang reng a ni.

Thisen tlakchhamna chhinchhiahna thenkhat chu hetiang hi a ni:

• Chak lohna emaw, hah lutuk emaw (chau tih hriat mai mai).
• Thâwk harsa (dyspnea) – hna tê tê thawk pawha thawk harsa.
• Thinlung thawk chak emaw, mumal lo emaw (arrhythmia).
• A chang chuan i beng bulah "whooshing" ri (pulsatile tinnitus) i hre thin.
• Lu na .
• Luak chhuak .
• Vun dum hring .
• A rilru a na .

Heng symptoms pakhat emaw a aia tam emaw i neih chuan doctor thurawn lak a tha ber.

Engvangin nge hetiang hi a lo awm? A chhan engte nge ni?

Heng thisen sen hring pianzia dik lo awm chhan hi chi hnih ah then theih a ni: inherited leh acquired . Condition thenkhat, Myelodysplastic Syndrome te hian a pahnih hi a thlen thei a ni.

Rochun Conditions te

A tam zawkah chuan congenital causes hi thisen sen pakhatin a lo thang lian a, a thawk tha a, a dam theih nan a mamawh genetic information (DNA) a dik lo vang a ni. Chutianga insiam dan pangngai lo nei thisen sen (red blood cells) te chu taksain cell thar a siam hmain an chhe nghal vat thin. Hei hi hemolytic anemia an ti a .

`(Poikilocytosis)` thlentu pianpui natna thenkhat:

• `(Hereditary Elliptocytosis)` tih a ni
• `(Hereditary Spherocytosis)` tih a ni
• `(McLeod Syndrome)` tih a ni
• `(Pyruvate Kinase tlakchhamna)`
• `(Sickle Cell Natna)` (Sickle Cell Natna) .
• `(Thalassemia)` tih a ni

Chûngte chu thlah kal zelah an lo inthlâkthleng fo ṭhîn.

Acquired Conditions te chu a ni

Hun a kal zel a, damdawi lam dinhmun thenkhat chuan thisen sen (red blood cells) pianzia a tidanglam thei bawk. Entirnan, taksain thisen zam hrisel siamna atana a mamawh nutrients, vitamin B12, folate, leh iron te a hmuh loh chuan thisen tlakchhamna chi hrang hrang a awm thei a ni. Poikilocytosis hi heng ei leh in lama tlakchhamna chhinchhiahna tlanglawn tak a ni. Natna, cancer thenkhat ang chi, thisen zam (red blood cell) siam chhuah tibuaitu vang pawh a ni thei bawk.

A hnu lama `(Poikilocytosis)` thlentu thenkhat chu:

• Autoimmune Hemolytic Anemia atanga lo chhuak a ni
• Kang (a zau a nih chuan) .
• `(Celiac Natna)`
• Infection chi hrang hrang
• Iron tlakchhamna avanga thisen tlakchhamna
• Kidney Natna a awm
• Leukemia (thisen cancer) 1.1.
• Liver Natna a awm
• Megaloblastic anemia (vitamin B12 emaw folate tlakchham vang emaw) .
• `(Myelofibrosis natna)` tih a ni
• Poisoning (e.g. lead) a awm thei.
• Thisen pek a nih chuan a chhân lêtna
• Splenectomy tih a nih chuan a chhanna
• Rul seh a ni

Hei hian eng harsatna nge a thlen theih?

Poikilocytosis thlentu dinhmun tam tak chu enkawlna hmangin enkawl theih a ni a, thenkhat chu tihdam vek theih a ni bawk. Mahse, enkawl loh chuan natna ṭhenkhat chu a nasat phah thei a, nunna atana hlauhawm pawh a ni thei. Entirnan, thisen tlakchhamna (anemia) i neih chuan i chau lutuk a, nitin hna i thawh theih loh khawpin i chau mai thei. Hun kal zelah thisen sen hrisel tak tak i hloh chuan organ failure ang chi dinhmun a thlen thei a ni .

A bik takin naupang tê têteah chuan thisen tlakchhamna enkawl loh a awm chuan an thanlenna leh an thanlenna a nghawng thei a ni.

Chuvangin, i doctor chuan i Poikilocytosis awm chhan dik tak a hriat chian hnuah, heng ang harsatna lo thleng tur venna tur hian a tul ang ang chu a pe ang.

Engtin nge hetiang chiah hian i diagnose? (Diagnosis) tih a ni.

Doctor-in poikilocytosis a hriat theihna atana a hman theih test ber chu peripheral blood smear (PBS) a ni. Hei hian lab technician pakhatin i thisen sample drop khat a la a, microscope hmangin a en a ngai a ni. Chumi hnuah chuan i thisen sen (red blood cells) engzat nge a pianzia danglam tak tih leh eng ang chi nge an nih tih an hmu thei ang.

Cell chi thenkhat chu natna chi hrang hrangah a tam zawk. Mahse, natna dinhmun inang chhungah pawh cell chi hrang hrang a awm thei. Entirnan, `(Hemolytic Anemia)`, `(Megaloblastic Anemia)`, `(Myelofibrosis)`, `(Thalassemia)` ang chi dinhmunah chuan cell chi hrang hrang pangngai lo engemaw zat hmuh theih a ni.

I doctor-te chuan i poikilocytosis thlentu dik tak hriat tumin test engemaw zat an tih belh a ngai mai thei.

`(Poikilocytosis)` awm chhan hriat nan test dang neih belh a ni

Thisen chhiar kimchang (CBC) hi PBS nen an ti fo thin. CBC hian i thisena cell awmte chungchang tam tak a pe thei a, an level leh size te pawh a pe thei bawk. CBC-a value thenkhat hian thisen sen chungchang hi a hriat belh theih a, hei hian Poikilocytosis awm chhan hriat theihna kawngah a pui thei a ni. Heng hlutnate hi a hnuaia mite hi a ni:

• `Mean Corpuscular Volume (MCV)` : I thisen sen zat zat zat.
• `Mean Corpuscular Hemoglobin (MCH)` : I thisen sen chhunga hemoglobin awm zat zatve.
• ``Corpuscular Hemoglobin Concentration (MCHC) awm zat zat''.: I thisen sen (red blood cells)-a hemoglobin awm zat zat (average value).
• `Red Cell Distribution Width (RDW)` : I thisen sen (red blood cells) te hi engtiang chiahin nge a lian dan a inang lo.

Chu bâkah, i doctor chuan i vitamin B12, folate, leh iron level a enfiah thei a, liver function test pawh a ti thei bawk.

Hei hi eng enkawlna nge ni?

Enkawlna chu i poikilocytosis awm chhan leh i natna lan chhuah dan a nasat danah a innghat a ni.

Hetiang dinhmun lo awm chhan hi ei leh in lama harsatna (e.g. iron, vitamin B12 tlakchhamna) a nih chuan, ei leh in lama a kaihhnawih ei emaw, vitamin B12 emaw folate emaw tamna ei leh in lama inthlak emaw hian he `(Poikilocytosis)` dinhmun hi a titawp thei fo tih hre reng ang che.

Congenital condition tam tak hi uluk taka enkawl a ngai a ni . Thisen sen hrisel tak tak i neih theih nan thisen pek fo i mamawh mai thei. A nih loh leh symptoms i neih leh neih loh a zirin enkawlna chauh i mamawh mai thei bawk.

Hetiang dinhmun hi ven theih a ni em?

``Poikilocytosis`` hi pianpui atanga lo awm thei chu kan veng thei lo.Mahse, a hnu lama lo awm thei thenkhat chu kan tihtlem thei a ni.

I thisen sen (red blood cells) enkawl dan tha ber pakhat chu i taksain a siam chhuah theihna tura a mamawh nutrients te i hmuh hi a ni. B vitamin, folate, leh iron te i ei tlem em tih enfiah rawh . Hengte hi i taksain thisen sen hrisel tak siamna atana a mamawh thil pawimawh tak takte an ni. Zu in tam lutuk tihtlem nan a pui bawk . Zu in tam lutuk hian i taksain heng nutrients te hi a hip harsa zawk thei a ni.

Nakin hun chu eng nge ni ang? (Hmuh dan tur) .

A tlangpuiin `(Poikilocytosis)` awm chhan hi a hnu lama lo awm a nih chuan prognosis a tha tlangpui. Congenital causes a nih chuan a hnuaia condition a zirin prognosis a inang lo. Entirnan, `(Sickle Cell Disease)` vei te dam rei zawng hi a tlangpuiin rei lo teah ngaih ni mahse, tunah chuan enkawlna thar hmangin kum 50 chuang dam theih a ni tawh a, chutih rualin a natna lan chhuah dan chu control theih a ni ta.

Engtikah nge Doctor i hmuh ang?

Anemia symptoms (kan sawi tawh, hahna leh chak lohna ang chi) i neih chuan doctor pan ngei ngei tur a ni.

Hrisel taka i inhriat a, symptom nei lo mah la, kum tin check-up neih a pawimawh. I doctor pawhin i thisen cell a check thei bawk. Thisen test awlsam tak, complete blood count (CBC) ang chi hian hriselna lama harsatna a nasat hmain hriatchhuah leh enkawl a pui thei a ni.

Hei hi ``Poikilocytosis'' hi natna khirh tak a ni em?

`(Poikilocytosis)` ngei pawh hi a pawi lo. Mahse, a niDamdawi lam dinhmun hnuaia awm chhinchhiahna a ni thei a, enkawl loh chuan harsatna a thlen thei a ni. Chuvang chuan `(Poikilocytosis)` thlentu dik tak hriat chian a, a tul chuan enkawlna zawn a pawimawh.

Poikilocytosis hi natna khirh tak angin a lang thei a, mahse chutiang chu a ni lo. Doctor ten i hriselna tehna atana an hman thin i thisen sen (red blood cells) ziarang mai a ni. I thisen sen (red blood cells) a dik lo tih i hriat chuan i doctor hnenah zawh hreh suh. I hriselna a nghawng em tih leh, a nghawng a nih chuan, chu natna tihbo emaw, a hnuaia dinhmun enkawl emaw tura i tih theih dan tur chu a hrilh thei che a ni.

Kan hriat reng tur pawimawh ber berte (Take-Home Message) .

Okay, chuti a nih chuan, kan sawi tawh atanga hriat reng tur pawimawh tak takte chu hengte hi a ni:

• Poikilocytosis chu i thisen sen 10% aia tam a pianzia dik lo a nih chuan a ni.
• Hei hi natna a ni lo va, mahse a hnuaia awmte chhinchhiahna a ni thei.
• Hetiang a nih chuan thisen tlakchhamna (chau, chak lohna, vun rawng) symptoms pawh hmuh theih a ni.
• A chhan chu pianpui emaw, acquired emaw (nutritional deficiencies, natna thenkhat) a ni thei.
• Hei hi thisen test awlsam tak (`PBS`, `CBC`) hmanga hriat theih a ni.
• Enkawlna chu a chhanah a innghat a, mahse enkawl theih a ni fo.
• Ei leh in hrisel neih hian a hnu lama lo awm chhan thenkhat chu a veng thei a ni.
• Symptoms i neih emaw, rinhlelhna i neih emaw chuan doctor pan a, thurawn lak a tha ber.

Chuvangin, he thu hi i tan a tangkai ngei ka beisei. Hrisel takin awm rawh!

` Poikilocytosis, Thisen sen, Thisen cell pianzia, thisen tlakchhamna, thisen test, hriselna, thisen tlakchham, thisen sen, thisen test