I kal (kidney) ah harsatna i nei em? Renal Cell Carcinoma (RCC) chungchang hi i zir dawn teh ang!

I kal (kidney) chungchang hi ngun takin i ngaihtuah ngai em? Kidney hi kan taksa peng te tak te pahnih mahse pawimawh em em pahnih a ni. Kan taksaah hian filter ang mai an ni. Mahse, a chang chuan heng kal (kidney) te hian harsatna an nei thei bawk. Vawiin hian cancer chi hrang hrang, kal (kidney)-a awm thei tam ber pakhat, "Renal Cell Carcinoma" emaw RCC emaw chungchang kan sawi dawn a ni. Lungngai suh, he thu hi awlsam takin, i hriatthiam theih dan tur angin kan sawi dawn a ni.

Renal cell carcinoma (RCC) tih hi eng nge ni?

A awlsam zawngin sawi ila, renal cell carcinoma (RCC) hi kal cancer chi khat zingah chuan a tam ber a ni. Kan kal hian tube network tha tak tak a nei a , chu chu tubules an ti a . Heng tube te hi taksa tui leh nutrients te thisenah a phur lut a, zun chhunga bawlhhlawh paih chhuaktu an ni. Heng tubules chhungah hian RCC hi a lo piang tan thin. Kidney cancer zinga 85% vel chu hetiang chi hi a ni.

A tam zawkah chuan RCC hi kidney pakhata cancer cells zungbun te tak te angin a intan thin. Hei hi tumor an ti bawk . Mahse, a châng chuan kal pakhatah, emaw, kal pahnihah emaw hian lump tam tak a lo awm thei a ni.

RCC chi hrang hrangte chu engte nge ni?

RCC chi hrang hrang a awm a. Chhungkaw khata mi hrang hrang awm ang maiin han ngaihtuah teh. He classification hi cancer cell-te microscope hmanga an lan dan, an DNA , emaw, an genetic material emaw atanga chhut a ni. A chi hrang hrang tlemte a awm a:

• Clear cell renal cell carcinoma (ccRCC): Hetiang chi hi RCC 85% vel a ni. A hming hi a chhan chu cancer cell te hi microscope hmanga chiang taka a lan vang a ni.
• Papillary renal cell carcinoma: Hetiang chi hi renal cell carcinoma zawng zawng zinga 10% leh 15% inkar a ni. Heng tumor-a kut zungtang ang chi protrusions ( papillae ) awm thin avanga hming vuah a ni.
• Chromophobe renal cell carcinoma: Hetiang chi hi 5% leh 10% inkar a ni. Heng cell te pawh hi a tlangpuiin a rawng a eng a, clear cell nen a inang a, mahse a lian deuh hlek a ni.
• Unclassified RCC: RCC 6% vel chu chi lian tham takah dah theih a ni lo. Mahse, scientist-te chuan he pawl hrang hranga thliar hran loh hi kawng thara thliar hran an tum chhunzawm zel a, chu chu cell-te microscopic characteristic leh an DNA ang chi thilte hmangin an thliar hrang a ni.

Doctor-te'n RCC chungchang an sawi hian "localized" emaw "advanced" emaw "metastatic" emaw tih thumal an hman hi i hre tawh mai thei. Localized RCC tih awmzia chu cancer hi kidney-ah chauh a awm tihna a ni a, a bul hnaia tissue-ah pawh a darh thei bawk. Metastatic RCC a niCancer hian taksa peng dangah a darh tawh tihna a ni. I neih chi hian i enkawlna tur leh i dam leh theihna tur a hril a ni.

RCC hi engtiang chiahin nge a awm?

Khawvel pumah kum tin RCC vei thar 400,000 vel an awm thin. United States-ah chuan mi 80,000 vel an ni. Tu pawhin RCC hi an vei thei a, mahse mipa kum 60 leh 80 inkar ah a tam ber .

Renal cell carcinoma natna lan chhuah dan chu engte nge ni?

Mi tam tak chuan a tir lamah symptom engmah an nei lo. Cancer a lo thang lian a, a chhehvel tissue emaw organ emaw a nghawng tan atang hian symptoms a lang tan thin.

RCC symptoms te chu:

• Zun chhunga thisen (hematuria) a awm. Hei hi a lan chhuah dan tlangpui a ni.
• Flank pain: Hei hian taksa sir lehlamah, kawr chunglam leh ruh hnuai lam natna a kawk a ni.
• Pum, hnungzang hnuai lam emaw, kawchhung (groin)-a lump awm ang maia hriatna.
• Chhan awm lova lo thleng thin khawsik.
• Zan a thawk hah.
• Sawifiah loha taksa rihna tlahniam.

Chu bâkah, thisen tlakchhamna chhinchhiahna , thawk hah leh hahna ang chi pawh a awm thei bawk. A nih loh leh paraneoplastic syndromes an tih natna lan chhuahna pawh a lang thei bawk. Hetiang a nih chuan cancer natna hrik a\angin hormone ang chi thil a chhuak a, chu chuan taksaah inthlak danglamna chi hrang hrang a thlen a ni.

RCC awm chhante chu engte nge ni?

RCC hi kidney tubules- a cell pangngai lo (abnormal cells) te chu thunun theih loha an lo thanglian tan chuan a lo awm thin. A chhan dik tak erawh hriat a la ni lo. Mahse, scientist-te chuan RCC vei theihna tipungtu risk factor thenkhat an hmuchhuak a ni.

Risk factors te chu engte nge ni?

Heng thilte hi i neih chuan RCC vei theihna a sang zawk:

• Meizial zuk: Meizial i zu tam poh leh a hlauhawmna a sang zawk.
• Obesity: I body mass index (BMI) a san poh leh i risk a sang zawk.
• Thisen sang (Hypertension).
• Chronic kidney disease: Hei hian hun rei tak dialysis hmanga enkawl te a huam a ni.
• Chronic Hepatitis C natna vei a ni.
• Hun rei tak chhunga natna tidamtu damdawi thenkhat (e.g. NSAIDs, acetaminophen) hman.
• Tun hmain a pum chhungah radiation therapy a lo dawng tawh bawk.
• Carcinogens, cadmium leh asbestos te nena inzawmna .
• Sickle cell natna: Hei hi RCC chi khat hmuh tur awm lo tak nen a inzawm a ni.
• Chhungkaw history-a kal cancer vei tawh.
• Genetic mutations: Hei hi cell DNA a inthlak danglamna a ni.
• Tuberous sclerosis natna hlauhawm tak a ni.
• Von Hippel-Lindau natna (VHL) a ni.

Heng risk factors zinga pakhat i neih chuan i doctor chuan kidney exam neih fo turin a rawt thei che a, chu chuan cancer hi a tir lamah a hriat theih nan a pui thei a ni.

RCC hi engtin nge kan hriat theih ang?

RCC vei zinga 25% vel chu cancer hi a darh tlem hnuah an vei tih hmuhchhuah a ni a, chu chu symptoms a lan tan tirh tihna a ni.

Mahse, thu lawmawm tak chu tunah chuan chhan dang vanga imaging test an tih hian RCC tumor chu accident-in an hmuchhuak nasa hle a, chu chu symptoms a lan hmain a ni. Chuvang chuan mi tam zawkin cancer hi a enkawl theih ber dinhmunah enkawlna an dawng chho zel a ni.

RCC hriat theihna tur test neih thin

Doctor-te chuan imaging test hmangin cancer an hriat theih nan leh enkawl dan tur ruahmanna an siam a ni. Test hman tlanglawn ber berte chu:

• Ultrasound scan: Hei hian taksa tissue kaltlangin high-frequency sound wave thawn a, monitor-a en theih tur image siam a ni. Ultrasound hian lump chu tui (chu chu cyst a ni fo thin ) emaw, solid (cancer natna hrik-ah a tam zawk) emaw a khat em tih hriat theih nan a pui thei a ni.
• Computed tomography (CT) scan: Hei hian thlalak hrang hrang a siam a, chu chuan taksa chhung lam chipchiar takin a tarlang a ni. Contrast an tih dye chu vein-ah i inject a ngai mai thei a, a hma leh a hnuah scan i neih a ngai mai thei. He dye hian cancer lam a pan a, chiang takin a lantir thin.
• Magnetic resonance imaging (MRI) scan: Hei hian magnet lian tak, radio wave leh computer hmanga taksa chhung lam chipchiar taka thlalak siam a ni. I doctor chuan CT scan i tih theih loh chuan (entir nan, a hmaa kan sawi tawh dye hi allergy i neih chuan), emaw, ultrasound leh CT scan result a chiang lo a nih chuan MRI tih a rawt thei bawk.

Biopsy hi cancer hriat theihna atan tih a ni tlangpui a, mahse RCC-ah chuan hei hi tih a ni tlem hle. Biopsy ah hian tumor atanga tissue sample te tak te lak a, microscope hmanga enfiah a, cancer cell awm leh awm loh enfiah a ni.

Mahse biopsying RCC hi a risky fo thin a, a chhan chu kidney a tichhe thei a ni. Chuvangin, doctor-te chuan enkawlna atan tumor pumpui an lak chhuah hnuah cancer cells an test fo thin. Imaging-in cancer a darh tawh tih a hriat chuan kal ni lo hmun dangah cancer cell an la thei a, an test thei bawk.

Heng cell te hi test hian eng ang RCC nge i neih tih chiang taka hriat theihna awmchhun a ni (imaging atanga a chiang lo a nih chuan). Chu cancer chi hrang hrang tan chuan eng enkawlna nge tha ber tih hriatchhuahna kawngah pawh a pui bawk.

Renal cell carcinoma awm dan tur (staging) a awm

I cancer stage hriat hian i doctor chu i cancer a darh zau zia a hriatthiam theih nan a pui a ni. Tin , cancer hi localized nge metastatic tih a hrilh bawk . He information hian i enkawlna tur ruahmanna siam turin a pui thei che a, prognosis chungchang pawh a hriat theih bawk.

Doctor-te chuan RCC stage an hriat theih nan TNM (tumor, lymph node, metastasis) an tih system an hmang a. Cancer hi stage I atanga IV thlengin an then a. Stage I, II, leh III cancer te hi localized anga thliar hran an ni a, stage IV hi metastatic RCC a ni thung.

• Stage I RCC: Cancer hi centimetre 7 aia te a ni a, kal pawnah a darh lo.
• Stage II RCC: Cancer hi centimetre 7 aia lian a ni a, mahse kal pawnah a darh lo.
• Stage III RCC: Tumor hi eng ang pawhin a lian thei a, kidney chhehvela tissue hnai tak takah a darh tawh bawk.
• Stage IV RCC: Cancer hi kal atanga kal chhuakin lymph node leh taksa peng dangte thlengin a darh tawh a ni.

Pawimawh: Cancer stage hriat hi enkawl dan tur hriat a pawimawh a, chuvangin doctor nen uluk takin sawiho rawh.

Khawiah nge RCC hi a darh hmasa ber?

Metastatic RCC hi i lymph node, lung, ruh, thin leh thluak ah a darh fo thin. A chang chuan i ovary emaw testicles emaw ah a darh thei bawk.

Renal cell carcinoma hi eng enkawlna nge ni?

Enkawlna hi thil tam takah a innghat a, chung zingah chuan cancer stage leh i hriselna zawng zawng pawh a tel. Localized RCC enkawl dan hi metastatic RCC enkawlna nen a danglam a ni .

Localized renal cell carcinoma enkawlna a ni

Hei hi enkawl dan chu cancer lakchhuah a ni a, a nih loh leh ablation technique hmanga cancer tihchhiat (cells te chu lum lutuk emaw, vawt lutuk emaw hmanga tihhlum) a ni.

Localized RCC enkawlna atana hman tlanglawn ber chu surgery a ni.

• Radical nephrectomy: Hei hian cancer nei kidney leh a chhehvela tissue thenkhat (lymph node leh adrenal glands te, cancer cell awmna hmun te) lakchhuah a ni. Mi tam zawk tan chuan kal hrisel pakhat chauh a tawk.
• Nephrectomy thenkhat tih a ni:Hei hian kal (kidney) cancer vei awmna hmun chauh lakchhuah a huam a ni. He surgery hi i cancer a tlem chuan tih theih a ni. Hei hian i kal hnathawh thenkhat a chhanhim thei a ni. Hei hi kal hrisel pahnih i neih loh chuan a pawimawh hle.

Surgery atana candidate tha tak i nih loh chuan i doctor chuan ablation tih dan tur a rawt thei ang. Chung zingah chuan:

• Cryotherapy: Cancer cell te hi freeze-in an that thin.
• Radiofrequency ablation: Cancer cell te chu lumna sang takah an dah a, an halral vek thin.

Metastatic renal cell carcinoma hmanga enkawl a ni

Metastatic RCC enkawlnaah hian taksa pum puia cancer cell awmte do a ngai a ni. Surgery hmanga tumor lakchhuah theih a ni a, mahse metastatic cancer tihbo vek tur chuan a tawk lo. Mahse, tumor lakchhuah hian symptoms a tihziaawm thei a, enkawlna dang tan pawh a tikhawtlai thei bawk.

Enkawlna hman tlanglawn ber chu immunotherapy leh targeted therapy te hi a ni . Thil chi hrang hrang a zirin heng damdawi te hi amah chauh emaw, a rualin emaw pek thin a ni.

Immunotherapy hmanga enkawlna te

Immunotherapy hian i immune system a tichak a, cancer cells a hmuh theih nan leh a do theih nan a pui a ni. Chung damdawi thenkhat chu:

• A rilru a buai em em a, a rilru a hah em em bawk a.
• A rilru a buai em em a, a rilru a hah em em bawk a.
• A rilru a buai em em a, a rilru a hah em em bawk a.
• A rilru a buai em em a, a rilru a hah em em bawk a.

Targeted therapy hmanga enkawlna te

Targeted therapies hian cancer cell tihpunna kalphung tibuaiin hna a thawk a ni. He enkawlna hian cancer cell-te thisen supply a tikhawtlai a, an thanlenna a tikhawtlai a ni. Chung damdawi thenkhat chu:

• Axitinib (Axitinib - Inlyta®) hmanga tihdam theih a ni.
• A rilru a buai em em a, a rilru a hah em em bawk a.
• A rilru a buai em em a, a rilru a hah em em bawk a.
• A rilru a buai em em a, a rilru a hah em em bawk a.
• A rilru a buai em em a, a rilru a hah em em bawk a.
• Pazopanib (Pazopanib - Votrient®) tih hi a tha hle.
• A rilru a buai em em a, a rilru a hah em em bawk a.
• Sunitinib (Sunitinib - Sutent®) tih a ni a, a man hi a to hle.
• A rilru a buai em em a, a rilru a hah em em bawk a.
• A rilru a buai em em a, a rilru a hah em em bawk a.

Cancer stage, a darhna hmun, a nasat dan, leh enkawlna dang i dawn dan azirin, i doctor chuan cancer enkawlna dang, radiation therapy ang chi chu a rawt thei a ni.

RCC hi a dam kim thei ang em?

I diagnosis bik ah a innghat. Localized RCC a niHigh-risk localized RCC nei te, an cancer surgery hmanga lakchhuah te hian hun rei tak chhung atan result tha tak an nei tlangpui. High-risk localized RCC vei te pawh cancer lakchhuah hnuah immunotherapy pek an ni thei bawk a, hei hian hun rei tak chhunga an result tha zawk a siam thei a ni.

Tunah hian advanced RCC, kidney piah lama darh tawh hi damdawi a la awm lo. Mahse, scientist-te chuan cancer cell bikte target-a enkawlna tha zawk an hmuh avangin tunah chuan metastatic RCC vei te chu an dam rei tawh hle.

RCC-te hmalam hun chu eng nge ni?

Tunah chuan doctor-te chuan RCC hi a tir lamah an hmu thei tawh zawk a, chutih lai chuan cancer hi enkawl theih a ni ber. A hmaa hmuhchhuah leh enkawlna tha zawkte chuan damchhuahna a tisang hle. Stage I RCC vei zinga 90% chu kum nga chhung an dam. Chutiang bawkin, stage IV RCC vei te dam rei zawng chu thla engemaw zat chauh a nih laiin, tunah chuan mi tam tak chu kum engemaw zat an dam tawh a ni.

RCC hi ven theih a ni em?

RCC hi a dang thei reng reng lo. Mahse i risk chu i tihtlem thei a ni. Entirnan, zu in loh (a nih loh leh zu in loh chuan) hi cancer vei theihna tihziaawmna atana i tih theih tha ber pakhat a ni. Tin, taksa rihna hrisel tak neih te, ei leh in inthlau tak ei te, thisen sang control te pawh a pawimawh hle.

Engtin nge ka in enkawl ang?

I cancer symptoms leh i enkawlna avanga side effects awm thei te enkawl dan tur care plan chungchang i doctor nen sawiho rawh. Entirnan, mi thenkhat chuan operation hnuah dialysis an tan a ngai mai thei a, chu chu kidney pakhat emaw, a pahnih emaw a thawk tha lo a nih chuan. Heng enkawlnate hian engtin nge a nghawng dawn tih hriat a pawimawh.

Targeted therapy emaw immunotherapy emaw avanga side effects awm thei tur enkawlna kawngah tanpuina i mamawh mai thei . Enkawlna i tan hmain i doctor hnenah eng nge i beisei tur tih zawt hmasa phawt ang che.

Doctor hnenah eng zawhna nge ka zawh ang?

• Eng ang RCC nge ka neih?
• Ka cancer hi eng chen nge a darh tawh (eng nge a stage)?
• Enkawlna awmsa te hian eng nge a thatna leh a that lohna?
• Enkawlna ka neih hmaa ka hriat tur side effects emaw complications te chu engte nge ni?
• Enkawl zawhah engzat nge check-up turin ka lo kal ang?
• Enkawl lai hian ka nunphungah eng inthlak danglamna nge ka beisei ang?
• Ka dinhmun hi eng prognosis nge ni?

Renal cell carcinoma (RCC) cancer enkawlna i tawn dan chu thil tam takah a innghat ang a, chung zingah chuan i hriselna zawng zawng, RCC chi leh stage, leh enkawlna i dawn dan te pawh a tel ang. Mahse kidney cancer vei nia hriat apiangin an medical team nena inzawmna nghet tak an neih chuan hlawkna an hmu ang. I natna hmuhchhuah dan te, enkawlna kawng hrang hrangte thatna leh that lohna te, leh a rah chhuah beisei dan te zawhna zawt hreh suh. RCC neih hi i tan eng nge a awmzia sawifiah turin i doctor hi a tha ber a ni.

A tawp berah chuan thil hriat reng tur

Renal cell carcinoma (RCC) hi natna khirh tak ni mah se, a hmaa hmuhchhuah leh enkawl dan dik a nih chuan a damna rate chu nasa takin a ṭha chho ta a ni. I natna lan chhuah dan, a bik takin i zunthlum-a thisen, i kawrfual na, i kut ah lump, emaw, chhungkaw history-a kal cancer i neih chuan doctor rawn la nghal rawh. Meizial zuk loh leh nunphung hrisel tak i hman chuan he natna vei theihna i tihziaawm thei a ni. Thil ngaihtuah tur i neih chuan doctor nen inbiakna neih hlau suh. Nangmah chauh i ni lo.

` Kal cancer, renal cell carcinoma, RCC, kal tumor, cancer symptoms, cancer enkawl dan, kal hriselna