Renin chu eng nge ni? Engtin nge i thisen sang a nghawng?

I taksa chhungah hian i thisen sang, chu chu thisen sang chu a level dik takah a awm reng theih nan eng mechanism mak tak nge hna thawk tih i ngaihtuah ngai em? Hmuh theih loh darkar ang mai a ni a, nalh takin hna a thawk a ni. Chuvangin, he thil pawimawh takah hian a changtu ber pakhat chu ‘Renin’ hi a ni. He hming hi i hre lo mai thei, mahse i hriselna atana a rawngbawlna hi a ropui hle. Vawiin hian he renin chungchang hi a awlsam zawngin sawi ila.

A awlsam zawngin, Renin chu eng nge ni?

Awle, a bul atang hian tan ila. Renin hi i kal chhunga cell chi khat bik atanga siam enzyme a ni. Enzyme chu kan taksaa chemical process ti chaktu protein a ni.

He renin hi thil pakhat chauh a ni lo. System pawimawh tak pakhata tel a ni. ‘Renin-angiotensin-aldosterone system’ kan ti a ni. Ngaihtuah buai suh, a hming hi a sei deuhin a ri mai thei. Thil kalphung inzawmkhawm (interconnected processes) chain a ni. He system pumpui hian a tum ber chu i thisen sang control-na tur a ni.

Engtin nge renin hian taksa chhungah hna a thawh? Hetiang hian he process hi a thleng thin!

Hei hi hrethiam tur chuan entirnan tlem han la ila. I taksa chu khawpui ang maiin han ngaihtuah teh, thisen kalna kawngte chu chu khawpui chhunga tui pipe chu a ni a, chu thisen chu chu pipe-a tui luang chu a ni. Tichuan thisen sang chu chu tui pipe chhunga pressure awm chu a ni.

Tunah chuan eng emaw chhan vangin he tui pressure (thisen sang) hi a tlahniam tih han ngaihtuah teh. Chuti a nih chuan eng nge thleng? Khawpui tui department (chu chu i kal (kidney) chuan hei hi an hre chiang hle. Chutah chuan kal (kidney) chuan thuchah (messenger) a chhuah tir nghal a. Chu palai chu renin a ni.

Thisenah renin dah a nih veleh hetiang hi a thleng thin:

1. Step hmasa ber: Renin hian a hmasa berin dormant protein angiotensinogen an tih chu a zawng a, chu chu liver-ah a siam a ni. Renin hian he protein hi a tichak a, angiotensin I ah a chantir thin.

2. Step 2: He ‘angiotensin I’ hi a la chak tawk lo. Thisen kaltlangin lungah a kal chuan chutah chuan enzyme dangin a chak zawk ‘angiotensin II’ ah a chantir a ni.

3. Step Pathumna: Tunah chuan hna tak tak chu a thleng ta. He agent chak tak ‘angiotensin II’ an tih hian thil pahnih a ti a.

• Pakhat chu, kan thisen kalna kawng (chu tui pipe) te chu a kal a, a tikhawtlai a ni. Chuti a nih chuan eng nge thleng? Pipe-te a inzawm khawm chuan pressure a sang a, thisen sang a sang bawk.
• Pahnihnaah chuan adrenal glands (kidney chunga awm gland te tak te pahnih) te chu aldosterone tih hormone siam turin signal a pe a ni.

4. A tawp ber atan:He hormone, aldosterone hian kal (kidney) te chu "taksa atanga chi (sodium) leh tui paih chhuah hi rei lo te chhung chu titawp turin a hrilh a ni." Hei hian taksaa tui awm zat a tipung a ni. Hei hian thisen sang a tisang bawk.

A awlsam zawngin, thisen sang a tlahniam chuan renin tia koh messenger a rawn lut a, he chain reaction zawng zawng hi a tan a, a tawpah chuan thisen sang chu a normal leh ta a ni. Hrethiam e?

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Engtikah nge taksa atanga renin a chhuah?

Kidney hian renin a chhuah chhan lian tak tak engemaw zat a awm. Chu chu kan taksa hian fing takin heng thilte hi a vil reng tihna a ni.

• Thisen sang hniam: Thisen kawng chhunga pressure sensor (baroreceptors) te hian thisen sang a tlahniam tih an hriat chuan kal (kidney) ah signal an thawn thin.
• Taksaah chi (sodium) level hniam: Kal (kidney) hian thisenah sodium a tlem tawh tih a hre thei. A awm chuan renin an chhuah tir thin.
• Nervous system function: Kan nervous system hi kan hlau emaw, kan chau emaw, exercise kan tih hian a tichak a. Heng hun lai hian Renin release a awm thei bawk.

Renin level enfiah nan test a awm em?

Ni e, a dik tak zet. I doctor duh chuan thisen test a ti thei a, i renin level a teh thei bawk. Hei hi ‘Plasma Renin Activity’ (PRA) tih test hmanga teh a ni tlangpui. He test hian i aldosterone level pawh a teh fo bawk.

Tunah chuan, "Engvangin nge he test hi ka mamawh?" Doctor-in he test hi a order chhan ber chu damdawi pangngai hmanga control harsa tak thisen sang i neih chuan a ni.

A chang chuan thisen sang hi ‘primary aldosteronism’ an tih, ‘Conn’s syndrome’ tia hriat bawk avanga lo awm thei a ni. Hetiang dinhmunah hian taksain hormone aldosterone a siam tam lutuk a. Chuvangin, i renin leh aldosterone level pahnih test hian i doctor chu i thisen sang chhan dik tak a hriat theih nan a pui thei a ni.

Renin level sang chuan eng nge a lantir?

I report-ah renin level sang tak a awm a nih chuan hriselna dinhmun hnuaia awm thenkhat a tarlang thei. Hei hi natna a ni lo va, a chhinchhiahna mai a ni.

Renin level tlahniam chhante chu engte nge ni?

Tin, renin level hniam lutuk hi thil engemaw vang a ni thei bawk.

Engtin nge renin level hi a hrisel theih ang?

Hei hi a pawimawh ber a ni. I renin level chu a mah chauhin i "feel" thei ngai lo. Renin level sang emaw hniam emaw hi natna a ni lo va, a hnuaia awm natna dang chhinchhiahna a ni zawk.

Chuvangin, i doctor hian a chinfel dan tur a pe tur a ni. I report chu a enfiah ang a, a tul chuan test dang a nei leh ang a, renin level dik lo awm chhan dik tak chu a zawng chhuak ang. Chumi chhan chu enkawl dan tur a ni ang.

Entirnan, thisen sang leh renin level sang i neih chuan i doctor chuan thisen sang tihhniamna damdawi, beta-blocker ang chi te a pe thei ang. A chhan chu dehydration a nih chuan tui tam tak in turin a fuih thei che a ni.

Renin level hi a complex hle tih hre reng ang che. Heng thilte hi nangmah chauhin lungngai suh. Thil ngaihtuah tur i neih chuan i doctor nen inbia ngei ang che. Amah hian thurawn leh enkawlna tha ber ber a pe thei ang che.