Doctorin nangmah emaw, i hmangaih tak emaw hnenah " hnute cancer" i nei tih a hrilh hian i khawvel pum pui chu a lo tla thla vek ang tih hi thil pangngai a ni. Hlauhna leh lungkhamna i rilruah a lo lang rual hian doctor-in a pek dan tur leh damdawi a pek dan chungchangah pawh zawhna sangkhat zet i nei bawk. "He damdawi hi taksa tan a tha em?", " Side effects a nei dawn em ni ?", "Hei hian hna a thawk tak tak ang em?" Chutiang thil chu i lu chhungah a tlan lut ngei ang. Chutiang chuan Tamoxifen, damdawi pawimawh tak, hnute cancer enkawlna atana hman lar tak , chu tunlai hian awlsam leh friendly takin kan sawi dawn a ni.
A awlsam zawngin, Tamoxifen chu eng nge ni?
Tamoxifen hi hormone receptor-positive hnute cancer enkawlna atana hman thin a ni . Pill (Nolvadex®) emaw liquid (Soltamox®) emaw angin a rawn thleng a.
Tunah chuan, "He hormone-a innghat cancer hi eng nge ni?" A awlsam khawp mai. Kan taksaa cancer cell thenkhat chu thlai te tak te ang mai an ni. Thlai pakhatin a thang lian tur leh a thang lian tur chuan tui leh chaw tha a mamawh ang bawkin heng cancer cell te hian a thang lian tur leh a darh theih nan estrogen emaw progesterone emaw hormone an mamawh a ni. Chu chu ‘hormone-dependent cancer’ kan tih chu a ni.
Tamoxifen damdawi hian a tih chu cancer cell-te mamawh estrogen hormone hnathawh a titawp a ni. Plant pakhat tan tui tap off ang mai a ni. Tichuan cancer cell te hian an thanlenna atana an mamawh thuchah an dawng lo.
Tin, doctor-te chuan he damdawi hi hnute cancer vei theihna sang tak nei (entir nan, chhungkaw zinga mi pakhatin cancer a vei tawh a nih chuan) cancer venna atan an rawt \hin bawk.
He damdawi hi tute tan nge recommended?
Tamoxifen hi hnute cancer vei zawng zawng tan pek vek a ni lo. I doctor chuan he damdawi hi i tan a tha em tih ngaihtuah turin thil tam tak a ngaihtuah ang a, i medical history leh cancer chi hrang hrang te pawh a ngaihtuah ang. A hnuaia thil thlengah hian hman a ni ber.
- Chhungkaw history-a cancer emaw BRCA gene mutations nei teChutiang thil avanga hnute cancer vei theihna sang tak nei te cancer venna atana hmalakna atan:
- Hnute cancer nei tawh leh surgery , chemotherapy , radiation therapy ang chi enkawlna nei tawhte cancer lo lang leh tur venna
- Hnute pakhata cancer vei tan hnute hrisel dang cancer veng.
- Cancer natna hmasa ber nei tan chuan, DCIS (ductal carcinoma in situ) ang chi tan chuan, a darh zel loh nan leh cancer na zawk a nih loh nan veng rawh.
A pawimawh ber chu he damdawi hi ei tur nge ei loh tur tih leh eng chen nge ei tur tih hi i doctor-in a siam vek tur a ni. Chuvangin hemi chungchanga zawhna i neih apiang chu i doctor nen sawiho hlau suh.
Tamoxifen hian eng hlawkna ber nge a neih?
Tamoxifen hi kum sawm tam tak chhung chu khawvel hmun hrang hranga hmeichhe maktaduai tam tak nunna chhanhimtu damdawi a ni. Chumi hlawkna chu a tlem lo hle a ni lo.
- Cancer lo lang leh tur a ti tlem: He damdawi hian enkawl hnua cancer lo awm leh theihna chu 30% atanga 50% in a tihtlem thei a ni .
- Hnute dang a humhim: Hnute pakhata cancer vei tawh tan chuan hnute dang cancer vei theihna chu 50% velin a tlahniam a ni .
- Cancer a veng: Risk sang tak nei tan chuan a tir atanga cancer vei theihna chu 40% velin a tlahniam thei a ni .
- Ruh a tichak: He damdawi hian ruh tihthianghlimna natna, a bik takin menopause hnua lo awm thin osteoporosis , a veng thei a ni.
- Cholesterol a tihniam: Tamoxifen hian taksaa cholesterol tha lo level tihhniam theihna a nei bawk.
Tamoxifen ei hian eng side effect nge a neih theih?
Damdawi dang ang bawkin Tamoxifen hian side effect engemaw zat a nei thei a ni. Mahse, chu chu i tawng vek dawn tihna a ni lo. Mi thenkhat chuan engmah an hre lo mai thei. Mi dangte chuan pakhat emaw, pahnih emaw an tawng thei bawk. Chûng thilte chu i hriat lâwkna chuan i hmachhawn tûrin a ṭanpui ang che.
Heng side effects te hi hmun hnih ah then ila.
| Side effect chi hrang hrang | Hrilhfiahna |
|---|---|
| Side effects awm fo, na lo zawk | |
| Menopause natna lan chhuah dan | Hot flashes, zan lama thawk hah, leh vaginal dryness te hi mi tam takin an tawn thin harsatna lian ber thenkhat an ni. |
| Thla tin thlasik hun inthlak danglamna | Menstrual cycle hi a mumal lo thei a, a tawp vek thei bawk. |
| I taksa rihna sang emaw, a hring emaw | Mi thenkhat chu an thau deuh mai thei. Mi dangte chuan an taksa chu tuiin a khat ang maiin a hring (edema) an nei thei bawk. |
| Harsatna tenau dangte | Mipaah hian vaginal discharge, nausea, vun rash, chau, lu na, ke hring, leh erectile dysfunction te hi mipaah a awm thei. |
| Risk rare mahse serious tak tak a awm | |
| Thisen a chhuak thin | Ke ruh chhunga thisen zam (deep vein thrombosis - DVT) emaw stroke emaw ang chi natna lo awm theihna a tlem hle. |
| Uterine cancer a ni | Tamoxifen hian endometrial cancer vei theihna a tipung deuh a, chu chu nausen pum chhunga lining a ni. Hei vang hian vaginal bleeding danglam tak i neih chuan doctor hnenah i hrilh nghal tur a ni. |
| Mit lama harsatna nei | Mitdel (cataract) vei theihna hi tlem a sang thei hle. |
It is important to remember that these serious side effects are very rare , mahse a finthlak a, heng symptoms zinga pakhat tal a awm chuan i doctor hriattir nghal tur a ni.
Engtikah nge doctor koh vat a ngaih?
Tamoxifen i ei a, a hnuaia symptoms te hi i neih chuan doctor hnenah hriattir nghal tur a ni a, a nih loh leh i hnai ber damdawi in Emergency Department (ETU) ah i kal tur a ni.
- I rilru natna emaw thawk harsatna emaw i neih chuan .
- Khawsik i neih chuan .
- Stroke symptoms i neih chuan - entirnan, tawng thiam lo, mitdel, taksa sir khatah (kut, ke, emaw hmai) a rilru a buai thut.
- I ke, i ke ruh emaw, i ke emaw a lo hring nghal a nih chuan (a bik takin i ke pakhat chauh).
- I luak chhuah kha i chawlhsan thei lo a nih chuan .
- Vaginal bleeding danglam tak i neih chuan .
Tamoxifen chungchanga zawhna awm fo dang thenkhat
Tamoxifen hi chemotherapy a ni em?
Ni lo, hetah hian mi tam tak an buai thin. Tamoxifen hi hormone hmanga enkawl a ni a . Damdawi chi khat, Selective Estrogen Receptor Modulators (SERMs) tih zingah a tel a ni. Chemotherapy hi cell inthen chak tak tak (cancer cells bakah cell hrisel te) thattu a ni. Mahse Tamoxifen hian kawng danglam takin hna a thawk a, hormonal level-ah a thawk a ni.
Naupai laiin Tamoxifen ei hi a him em?
Ni lo tak zet a ni. Tamoxifen ei laiin naupai hian nau piangsualna nasa tak a thlen thei a ni . Chuvangin he damdawi hi i ei a nih chuan naupai loh tur a ni . Hetih lai hian hormonal birth control (birth control pill ang chi) hi a tha lo hle a, chuvangin hormonal ni lo birth control method (condom emaw IUD ang chi) hman chungchang hi doctor nen sawiho rawh. Damdawi kan chawlhsan hnuah thla hnih tal birth control hman a pawimawh.
Tamoxifen i ei lai hian eng ei leh in nge i ei loh tur?
Awle. Ei leh in thenkhat hian Tamoxifen thatna a ti tlem thei a ni. Chuvangin hengte hi pumpelh a tha ber ang:
- Grapefruit a ni
- Tangerines a ni
- Zu chi hrang hrang
Damdawi ei tan hnuah side effect a awm nghal em?
Hei hi mi tin a inang lo. Mi thenkhat chuan pill hmasa ber an ei ni atang khan inthlak danglamna tenau te an hmu tan thei. Mi dangte chuan thla tam tak chhung chu engmah an hre lo mai thei.
Damdawi hi a chawlhsan hnuah eng chen nge taksaah a awm reng?
Tamoxifen hi pill hnuhnung ber i ei hnuah kar hnih vel taksaah a thawk reng a, mahse i taksa atanga a chhuah vek theih nan thla thum vel a la ngai thei.
Take-Home Thuchah a ni
- Tamoxifen hi hormone hmanga enkawl hnute cancer enkawlna tha tak a ni.
- He damdawi hian cancer lo awm leh theihna leh a lo thang thar theihna a ti tlem hle.
- Damdawi ei hian side effect a neih theih dan tur ngaihtuah buai suh. A tam zawk chu enkawl theih a ni. Mahse symptom na tak tak a awm chuan fimkhur la, a lo awm chuan doctor hnenah hrilh nghal rawh.
- He damdawi hi doctor-in a pek hun chhung zawng zawng ei chhunzawm zel a pawimawh hle.
- Zawhna emaw, ngaihtuahna emaw i neih chuan i doctor nen sawiho rawh. I dikna a ni.
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