Cancer dona hi a harsat zia kan hria. Doctor-te'n "gene therapy" tih ang chi thumal thar, buaithlak tak tak an sawi hian rilru hah lutuk hi thil pangngai a ni. Mahse, lungngai suh. Vawiin hian chutiang enkawlna bik pakhat kan sawi dawn a ni. Mahni taksa cell hmang a, training tir a, cancer cell tichhe turin i tirh kha han mitthla teh. Chu chu he damdawi Tisagenlecleucel an tih hian a ti a ni. A awlsam leh chiang takin sawi ila.
Tisagenlecleucel (KYMRIAH) tih hi eng nge ni?
A awlsam zawngin, hei hi i pill ei emaw, damdawi pangngai i vein-a i inject emaw a ni lo. Tisagenlecleucel hi gene therapy a ni a . I immune system atanga cell chi khat lak a, lab-a siam danglam a, cancer cell hriat theihna leh beih theihna tura zirtirna a ni.
A dik tak chuan kan taksa hian fighter cell chi khat T-cell an tih hi a nei a. Heng cell te hi natna dotu an ni. He enkawlnaah hian doctor-te chuan heng T-cells thenkhat hi i taksa atangin an la chhuak thin. Tichuan, lab-ah chuan genetic technology hmangin heng T-cell-te chungah hian "special glass" pahnih an dah a. Chu chu, heng cell te hi cancer cell chunglama marker bik an hriat theih nan an siam danglam tihna a ni. Tichuan, heng "superpowered" T-cell maktaduai tam tak hi an lo thang lian a, i taksaah vein hmangin an inject leh ta a ni. Tunah chuan heng trained cells te hi cancer cells ah hian an kal nghal a, an zawng a, an tichhia a ni.
He enkawlna hi cancer chi hrang hrang enkawlna atan hman a ni ber a, chung zingah chuan acute lymphoblastic leukemia (ALL) , leukemia chi khat, leh non-Hodgkin lymphoma te pawh a tel.
Enkawlna i tan hmaa i doctor hnena i hrilh tur thilte
Hei hi mahni cell hmanga enkawlna ni mahse, i tan hmain i care team nen inbiakna zau tak neih a pawimawh hle. A hnuaia mite hi hriattir tur a ni:
- Tuna hri kai: Tunah hian natna i neih chuan min hrilh la, chu chu khawsik, khuh, khawsik, zun kawng infection te hi a ni.
- Inflammatory conditions: Taksa khawi hmunah pawh inflammatory disorder awm apiang chu doctor hnenah hrilh rawh.
- Allergy: He damdawi chauh ni lovin, damdawi dang, ei tur emaw, dye dang emaw allergy i neih chuan min hrilh ngei ang che.
- Naupai: Naupai i nih emaw, nau pai tum emaw, naupai nia rinhlelhna i neih chuan i doctor hnenah hrilh nghal rawh. Hei hi a pawimawh hle.
- Nau hnute pek: Naute i hnute i pek chuan doctor pawh hrilh bawk ang che.
Engtin nge he enkawlna hi i pek?
He enkawlna hian step engemaw zat a huam a, damdawi in emaw, specialized clinic emaw-a medical team enkawlna hnuaiah tih a ni.
1. Cell lakkhawm: Enkawl hma kar 3-4 vel ah i taksa atanga T-cells lakkhawm a ni. Hei hi leukapheresis tih hmanga tih a ni . Thisen pek nen a inang a ni. Thisen hi vein atanga lak chhuah a ni a, machine bik hmanga kalpui a ni a, chu chuan thisen var cell te, T-cells te pawh a then chhuak a, chutah chuan thisen la awm chu i taksaah dah leh a ni.
2. Cell training: Heng cell khawlkhawmte hi lab-ah thawnin cancer do turin training pek an ni.
3. Infusion: Cell te chu training leh thanglian an nih hnuah, saline solution ang deuhin vein hmangin i taksaah an infuse leh thin. Hetiang zawng zawng hi damdawi inah a thleng vek a ni.
A pawimawh ber chu he damdawi hi i cell atanga siam a nih avangin i tan chuan personalized treatment a ni . Chuvang chuan he damdawi hi mi dang nena insem theih a ni lo.
Enkawlna neih huna ngaihtuah tur thil
He enkawlna chhung hian i dinhmun hi i doctor-te chuan uluk takin an enfiah ang. Hengte hi i hriat chian a ngai bawk.
- Mut theih lohna leh lirthei khalh: I muhil thei a, i lu a buai thei bawk . So , rilru fimkhur ngai thil engmah, lirthei khalh emaw, machine rit tak tak hman emaw ang chi chu ti suh, he damdawi hian engtin nge a nghawng che tih chiang taka i hriat hma loh chuan.
- Infection hlauhawmna: He enkawlna hian hun engemaw chen chu i taksain natna a do theihna a ti tlem thei a ni. Chuvangin damlote lakah inthiarfihlim tum ang che. Khawsik, taksa na, emaw, rilru na ang chi symptoms i neih chuan , mahni damdawi ei ai chuan i doctor ko nghal rawh.
- Thisen emaw taksa peng emaw pek: He damdawi hi i ei lai leh a hnu hun engemaw chen chu thisen, taksa peng, tissue, sperm, emaw egg (oocyte) pek loh tur.
- Naupai (Pawimawh tak): He damdawi ei lai hian eng vangin naupai suh . Tin, naute neih i tum emaw, naupai nia i rinhlelh emaw chuan doctor hnenah i hrilh nghal tur a ni. He damdawi hian nausen piang lo chu nasa takin a tichhe thei a ni.
- Damdawi dang: Damdawi dang i ei tur (vitamin leh herbal remedies te pawh tel) i doctor hnenah hrilh rawh. A bik takin tun dinhmunah vaccine nung (live vaccine) a awm lo.
- Rikrum:Hei hi damdawi inah pek a nih avangin damdawi i ei tam lutuk lovang. Mahse, emergency a lo awm chuan medical team te hriattir nghal tur a ni. A tul chuan Emergency Treatment Unit (ETU) ah an refer ang che . Poisoning i rinhlelh chuan Colombo National Hospital-a National Poisons Information Center-ah i call thei ang .
He damdawi hian side effect a neih theih dan
Damdawi zawng zawng ang bawkin he damdawi hian side effect a nei thei. Chung zinga ṭhenkhat chu report nghal tur a ni a, ṭhenkhat erawh chu a pawi lo hle thung. A hnuaia table hi en rawh.
| Side effect hrang hrangte thliar hranna | |
|---|---|
| I doctor emaw medical team emaw hnena report nghal tur thil | |
| Allergy nei te pawh a awm | Vun vun rawng, hnim hring, hmai, hmui emaw lei emaw a hring. |
| Thâwk lak harsat | Thâwk harsa. |
| Rilru lam inthlak danglamna | Buaina, thusawi emaw hriatthiam harsat. |
| Thisen cell count tlahniam chhinchhiahna | Infection symptoms: khawsik, khawsik, ril na. Thisen chhuak chhinchhiahna: hliam, vunah hmun sen, bawlhhlawh dum, zun chhunga thisen awm. Thisen sen (red blood cell count) tlem: hah lutuk, muthilh, paleness. |
| Symptom na tak dang a awm bawk | Diarrhea, balance hloh, taksa ruh emaw ruh natna, luak chhuak, luak chhuak, seizures, thisen sang tlahniam chhinchhiahna (luak, luak chhuak). |
| A awm reng emaw, a buaithlak emaw chuan doctor hnenah hrilh rawh. | |
| Side effect awm fo thin | Constipation, chaw ei chak lohna, lu na, pum na, ke leh ke ruh na. |
He list-ah hian side effect awm thei zawng zawng a tel lo. Thil danglam tak i tawn chuan i doctor nen sawiho rawh.
Take-Home Thuchah a ni
- Tisagenlecleucel hi personalized gene therapy a ni a, nangmah ngeiin i immune cells hmangin cancer enkawl a ni.
- Hei hi damdawi inah enkawlna bik a ni a, leukemia leh lymphoma natna khirh tak tak tan pawh hman thin a ni.
- Enkawl i tan hmain i hriselna chungchang zawng zawng (infection, allergy, naupai) doctor hnenah i hrilh hmasak a pawimawh hle.
- Enkawl lai hian a bik takin hri kai chhinchhiahna (khawsik, khuh) te fimkhur tur a ni. Chutiang chhinchhiahna a lo awm chuan damdawi lam thurawn la nghal rawh.
- I mutthilh theih avangin, i dam kim hma loh chuan lirthei khalh leh ngaihven ngai hna thawh loh tur a ni.
- Enkawl lai hian naupai loh vek tur a ni . Hei hi a pawimawh hle.
- I ngaihtuahna emaw rinhlelhna emaw i neih chuan i medical team te nen inbiakna neih hlau suh. I tanpui turin an awm reng a ni.
💬 Comments (0)
Comment a la awm lo. Hetah hian i comment hi a vawikhatna atan add rawh.
I comment kha add rawh