Migraines tan Triptans chungchang hi i zir belh ang u.

I lu a puak dawn ang maia i lu na, a sir khatah chauh na tak i nei tawh em? I luak duhna, êng en thei lo, thawm i hriat chuan i thinrim bawk em? Hei hi migraine kan tih chu a ni. Hei hi lu na pangngai mai a ni lo. Hei hi thluak nena inzawm condition a ni. Mi thenkhat tan chuan he hrehawmna hi tuar theih loh a ni. An tih theih awmchhun chu pindan thim leh reh takah ṭhuin an natna reh hun nghah mai a ni. Chuvangin nang pawhin he natna hi i tuar a nih chuan damdawi chi khat `Triptans` tih hi i hriat a pawimawh hle.

Triptan-ho chu eng nge ni?

A awlsam zawngin sawi ila, `Triptans` hi damdawi chi khat, migraine enkawlna atana pek thin a ni. Hei hi migraine enkawlna line hmasa ber a ni. Heng damdawi te hian migraine lo awm tur chu a veng thei lo (special case tlemte tih loh chu), mahse vawi khat a lo awm tawh chuan a titawp thei a ni.

Heng damdawi, `Triptans` tia koh hi kum 1980 chho vela hmuhchhuah a ni a, migraine enkawlna kawngah pawh thil danglam tak a thlen a ni. Hemi atana damdawi pawmpui hmasak ber chu `Sumatriptan` a ni. `Triptan`s` dang eng emaw zat chu a hnuah an rawn luhtir leh bawk.

Engtin nge triptans te hian hna an thawh?

Hei hi hrethiam tur chuan natna kan hriat dan hi kan en hmasak a ngai a ni. Kan taksa chhunga nerve te hian direct-in natna an hre lo. Chu ai chuan kan thluak lamah taksaah thil a awm tih signal an thawn a, chu chu hliam emaw, hri kai emaw ang chi hi a ni. Thluak hian chu signal chu "natna" kan tih angin a letling a ni.

Scientist-te chuan migraine hi engtin nge a awm tih hi 100% in an la chiang lo a, mahse thil pawimawh pathum hian a thlen niin an ngai a:

1. Neuron activation: Migraine lai hian thluaka nerve cell (neurons) thenkhat chu a remchan loh zawngin an thawk chhuak thin. Hei hi natna leh symptom dangte thlentu a ni.

2. Thisen kal dan a danglam: Migraine a lo awm chuan thluaka thisen kalna kawng a zim a, a zau a, chu chuan thisen kal dan a tidanglam thin.

3. Inflammation: Thluaka inflammatory chemical thenkhat pawh hi migraine thlentu nia ngaih a ni bawk.

Tunah chuan `Triptans` hian heng process te hi engtin nge a nghawng tih kan en ang. Kan thluak hian `Neurotransmitter` a nei a, chu chu `Serotonin` tih a ni a, chu chu chemical messenger a ni a, nerve inkara thuchah a keng tel a ni. Damdawi `Triptans` te hian he `Serotonin` ang chiah hian hna an thawk a ni. Thluak chhunga `receptor` chi hrang hrang pathum nen an inzawm a. Heng `receptor` te hi lock chabi angin ngaihtuah la, `Triptans` te hi anmahni nena inmil chabi ang an ni.

• 5HT1B receptors: Hengte hian thluaka thisen kalna kawng zau zawng a control a. Triptan hian heng receptor te hi a tichak a, migraine laia thisen kalna kawng, a tul lo taka zau tawhte chu a ti tawi thei a ni.
• 5HT1D leh 5HT1F receptor: Hengte hian thluaka natna signal phurtu nervous system hnathawh a ti tlem a. Chu chu thluaka natna signal a thlen loh nan an titawp tihna a ni.

Hei hi triptans hian migraine natna leh symptom dangte a control dan a ni.

Eng ang triptan nge awm?

Tunah hian triptan chi sarih hman mek a ni. Heng damdawi zawng zawng hi an hminga "-triptan" tih hmunah a tawp vek a, chu chuan hriat a awlsam phah hle. I doctor chuan eng triptan chi nge i tan a tha ber tih a rel ang.

Triptans hian eng hlawkna nge a neih?

Triptan hi migraine vei tan chuan chhan hrang hrang avangin malsawmna ropui tak a ni.

• Side effects tlem zawk: Migraine damdawi hmasa nena khaikhin chuan Triptans side effects hi a tlem zawk hle a, chutiang chuan a na lo hle.
• Addictive lo: Mite chu painkillers, a bik takin opioids te hi an addicted thei a ni. Mahse, triptans hi addiction a ni lo.
• Safe: A tlangpuiin Triptan hi damdawi class him tak a ni.
• A chi hrang hrang a awm: I hmuh angin he damdawi hi pill ang chauh ni lovin, hnar spray leh injection atan pawh a awm. Pill ei harsa emaw, luak chhuak emaw tan chuan spray emaw injection emaw hman theih a ni.

Side effects leh triptans hmanga hriat tur thil

Damdawi dang ang bawkin Triptan hian side effect tenau tak tak a nei thei a ni. Mahse, mi zawng zawngin an hmu vek lo va, an dawng a nih chuan an serious lo tlangpui.

• Luak chhuak thei
• Mutthilh emaw, hahna emaw
• Flushing a ni
• Luhai
• Kawng a na
• Thawmhnaw hak
• Ke ruh leh ke ruh (limbs) a natna (numbness) a awm
• Chak lo anga inhriatna
• A tlem hle a, i rilru a na emaw, i tight emaw pawh a awm thei.

Tute nge triptan ei loh tur?

Triptan hi hriselna lama harsatna nei tan chuan a tha lo hle.

• Lung natna emaw, thisen kalna lama harsatna: Lung natna, thisen sang control loh (unmanaged hypertension), stroke, emaw transient ischemic attack (TIA) i neih tawh emaw, i neih hlauhawm emaw a nih chuan, i doctor chuan he damdawi hi a rawt lo mai thei.
• Damdawi dang (Drug interactions) chungchanga harsatna awmte:Triptan hian damdawi dang i ei lai nen a inzawm thei a, a bik takin ergotamine awmna, migraine enkawlna atana hman thin te nen a inzawm thei a ni. Chuvangin i damdawi ei zawng zawng, vitamin pawh nise i doctor hnenah hrilh ngei ang che .**
• Nu naupai emaw, nau hnute pe lai emaw: Naupai emaw, naupai tum emaw, nau hnute pe emaw i nih chuan triptans hman dan tur chungchangah i doctor nen inbiakna neihpui ngei tur a ni.

Engtikah nge doctor i hmuh ang?

Triptans hian i nitin hnathawhna a tibuai a nih chuan, emaw, i damdawi ei kha a hma angin a thawk tha lo nia i hriat chuan i doctor nen inbia ang che.

Emergency damdawi lam pan hun tur:

Triptan hian side effect na tak a nei tlem hle. Mahse, a hnuaia symptoms te hi heart attack emaw stroke emaw ang chi i neih chuan damdawi in emergency department (ETU) ah kal nghal rawh.

• Chhung natna nasa tak emaw, tightness emaw
• Thinlung thawk mumal lo (rang, slow) .
• Thâwk harsa
• Taksa sir khatah rilru hahna, chak lohna emaw, paralysis emaw.

Migraine vei thenkhat chuan stroke ang chi symptom an nei thei. Mahse, in lamah chuan migraine symptom nge stroke tih hi kan hre thei lo. Chuvangin , rinhlelhna i neih chuan a him ber chu damdawi lam thurawn lak nghal hi a ni.