I doctor chuan i cholesterol tihhniamna tur damdawi a pe em? I la pawh a ni mai thei. Chungte chu statin an ti a. Heart attack leh stroke ang chi natna khirh tak tak lakah min humhim thei a ni. Mahse a chang chuan heng damdawi te hian hrehawmna a thlen thei a, a bik takin taksa ruh natna a thlen thei. Chutiang a nih chuan he thuziak hi i tan a pawimawh hle ang. Vawiin hian mi tam takin harsatna an neih, ‘statin intolerance’ an tih chungchang kan sawi dawn a ni.
A hmasain, statin hi eng nge ni? Engvangin nge an hman?
A awlsam zawngin sawi ila, statins hi doctor-te'n kan liver leh thisen a cholesterol "tha lo" level tihhniamna atana an pek thin damdawi chi khat a ni. Heng hmingte hi i hre tawh mai thei: Atorvastatin, Rosuvastatin, Simvastatin te hi Sri Lanka rama statin hman tlanglawn ber pawl an ni.
Tunah chuan cholesterol chungchang tlem han hrethiam ila. Kan taksaah hian cholesterol chi hnih kan nei ang tih han ngaihtuah teh. Pakhat chu ṭhian ṭha ang a ni a , pakhat chu hmêlma ṭha lo ang a ni .
- Cholesterol tha (HDL): Kan taksaah hengte hi kan neih tam poh leh a tha zawk, a chhan chu thinlung natna leh stroke ang chi natna lakah min venghim a ni.
- Cholesterol tha lo (LDL): Hengte hi kan hmelma te an ni. Thisen an pun chuan kan thisen kalna kawngah an deposit a, a tikhawlo a, heart attack leh stroke vei theihna a tipung a ni.
Statin damdawi hian bad cholesterol (LDL) level tihhniamna hmangin hna a thawk a ni. Chuvangin, heng damdawi te hian lung natna vei hlauhawmte chu hrisel zawk leh dam rei zawk turin a pui thin.
Chuti a nih chuan, ‘statin intolerance’ chu eng nge ni?
Statin intolerance chu statin pakhatin a thatna aiin a side effect a tam zawk a nih chuan a ni. Hei hian i taksa hian damdawi chu a "tolerate" thei lo tihna a ni. Hei hi allergy emaw, adverse reaction dang emaw a ni thei.
Chutiang a lo thlen chuan i cholesterol tihhniam nan damdawi chu i hmang thei tawh lovang. Vawi tam tak chu, a lan chhuahna ber chu taksa ruh natna, rilru natna, a nih loh leh chak lohna a ni .
‘Statin Intolerance’ natna lan chhuah dan tlangpui.
Statin i hman tan tawh a nih chuan heng symptoms te hi lo thlir reng ang che.
| Chhinchhiahna | Hrilhfiahna |
|---|---|
| Muscle na a na | I thawk chhuak mai mai ang maiin a lang a, i taksa ruh a na. |
| Nunna nei lo taksa | Hna pangngai pawh thawk thei lo khawpa chak lo anga inhriatna. |
| Taksa natna | Ruh leh ruh natna leh natna awm reng. |
A pawimawh ber: Heng symptoms te hi i neih chuan damdawi i chawlhsan hmain doctor nen inbiakna neih hmasak phawt ang che. Heng symptoms te hi damdawi i ei tawh loh hnuah a bo tlangpui. Mahse, heng symptoms te hi i tawn chhunzawm zel a, damdawi i ei chhunzawm chuan i taksa ruh a tichhe vek thei a ni.
‘Statin Intolerance’ lo awm theihna tur risk factors te chu engte nge ni?
Mi thenkhat chuan he natna hi an nei tam zawk. Heng risk factors te hi category hnih ah then ila. Ṭhenkhat chu kan thlak danglam thei lo va, ṭhenkhat erawh chu kan enkawl thei a ni.
| Risk factor chi hrang hrang | Entirnan |
|---|---|
| Thil danglam thei lo |
|
| Manageable factors te pawh a awm |
|
Engtin nge doctor hian he natna hi dik taka a hriat theih ang?
I doctor i hmuh hunah i natna lan chhuah dan te, damdawi dang i ei lai te, leh i chhungkaw damdawi lam chanchin te a zawt hmasa ang. Tichuan, statin te hian i natna lanchhuahna a thlen em tih emaw, damdawi lam natna dang a awm em tih emaw hriat tumin test thenkhat an ti thei ang.
- Thisen test: Hengte hian liver enzymes, muscle enzymes (Creatine Kinase), leh damdawi lam thil dangte chu a paih chhuak thei a ni.
- Muscle testing: Taksa chak lohna enfiah.
- Test dang: Genetic test emaw muscle biopsy emaw tih a tha thei a, mahse hengte hi tih tlem a ni tlangpui.
‘Statin intolerance’ i neih chuan eng nge a chinfel theih ang?
Doctor chuan he natna hi i nei tih a rel ta niin han ngaihtuah teh. Lungngai suh. A chinfel dan tur engemaw zat a awm.
1. I damdawi ei zat thlak danglam: I doctor chuan statin ei zat a tihtlem thei a, a nih loh leh i natna lan chhuah dan a that leh that loh en turin hun engemaw chen chu damdawi ei kha a chawlhsan thei bawk. A châng chuan, statin chi dang hmangin an switch thei che a ni.
2. Statin ni lo damdawi dang: Statin hman theih loh chuan cholesterol tihhniamna damdawi chi dang a awm.
- ACL inhibitors: Hengte hian liver-in bad cholesterol (LDL) a siam chhuah a tikhawtlai a ni.
- PCSK9 inhibitors: Hengte hian kan taksaa protein bik pakhat chu a titawp a, taksa atanga cholesterol tha lo (LDL) paih chhuahna kawngah a pui bawk.
- Fibrates: Hengte hian cholesterol tha lo (LDL) a tihziaawm bakah cholesterol tha (HDL) a tipung bawk.
- Bile acid sequestrants: Hengte hian thisenah cholesterol a luh leh theih loh nan a veng a ni.
3. Nunphung thlak danglam: Hei hi a pawimawh hle. Damdawi ei leh ei loh pawhin heng thilte hian i cholesterol level control turin a pui thei a ni.
- Ei leh in hrisel: Oil, sugar leh chi ei tlem la, thlai, thei leh thlai chi ei tam rawh.
- Exercise: Nitin kea kal emaw, tui chawi emaw ang chi thil tih.
- Thil tih \ha lo bânsan: zu in leh zu in bânsan.
4. Supplements: A then phei chuan i doctor chuan taksa ruh natna tihziaawmna turin vitamin D emaw Coenzyme Q10 (CoQ10) ang chi supplement ei turin a rawt mai thei. Mahse, hengte hi i tan hmain doctor rawn hmasak phawt a pawimawh.
Take-Home Thuchah a ni
- Statins hi cholesterol tihhniam nan leh lung natna laka invenna atan damdawi pawimawh tak a ni. Mahse, mi thenkhatah chuan side effect an nei thei a ni.
- Muscle na leh chak lohna hi ‘Statin Intolerance’ chhinchhiahna ber a ni. Hengte hi fimkhur rawh.
- Heng symptoms te hi i neih chuan nangmah chauhin i damdawi ei kha bansan ngai suh. I doctor nen inbia hmasa phawt ang che.
- ‘Statin intolerance’ i nei a nih pawhin damdawi dang leh i cholesterol control dan tur a awm. Chuvangin hlau suh.
- Cholesterol control nan nunphung hrisel neih hi a pawimawh hle.
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