Ka ngawari te totoka? Me ako tātou mō te ngoikore o te Antithrombin!

Ahakoa he patunga iti kei tō tātou tinana, ka mutu te toto i muri i tētahi wā, ā, ka piri te toto, tika? He tikanga whakamiharo tēnei mā tō tātou tinana hei tiaki i a ia anō. Heoi, ki te nui haere te piri o te toto i te mea e tika ana, ki te puta rānei he piri toto i roto i te tinana me te kore take? Kātahi ka waiho hei raruraru. I tēnei rā ka kōrero tātou mō tētahi take motuhake e piri ai te toto me te koretake. Ko te ngoikore o te Antithrombin , e kīia ana hoki e ētahi ko te ngoikore o te Antithrombin III.

He aha rawa te ngoikore o te Antithrombin?

I roto i tēnei, ko te korenga o te antithrombin he āhuatanga e pā ana ki te tukanga toto totoka. I roto i tēnei, he hekenga pea o te pūmua e kiia nei ko te antithrombin, he matū nui i roto i tō tātou tinana e ārai ana i te toto totoka nui, kāore rānei e mahi tika.

Whakaarohia pēnei. Kei te whakakī koe i tētahi kaukau ki te wai. Me whakaweto te taputapu i mua i te puea ake, ki te kore ka maringi katoa te wai. Koinei te āhua, ina tīmata te toto ki te totoka, ko te mea e kiia nei ko te antithrombin te "aukati" i te wā tika, ka ārai i te nui rawa o te totoka. Nō reira, ki te kore e nui te antithrombin i roto i tō tinana, ki te kore rānei e mahi tika, ka puta tonu ngā totoka totoka, pērā i te puea ake o te kaukau. Koinei te take ka nui ake tō tūponotanga ki te whakawhanake i ngā totoka toto rerekē .

Ko te hunga whai mate pēnei ka tino mōrearea ki te whakawhanake i ngā toto totoka i roto i ngā uaua hohonu o ngā waewae ('Deep Vein Thrombosis', 'DVT' rānei) me te mōrearea o te pakaru o te toto totoka ka piri ki roto i te uaua o ngā pukahukahu ('Pulmonary Embolism', 'PE' rānei) . He tino mōrearea ēnei āhuatanga.

He pēhea te noa o tēnei āhuatanga?

He mate tino onge te ngoikore o te Antithrombin. E kiia ana kotahi anake i roto i te 2,000 ki te 3,000 tāngata e pāngia ana e tēnei mate. Ehara i te mea kāore e pā ki te katoa.

He aha ngā tohu o te korenga o te antithrombin?

Ehara i te mea ka rite ngā tohu o te katoa e pāngia ana e tēnei mate. Tērā pea kāore he tohu o ētahi tāngata. Heoi, ko te nuinga o te wā ka puta te toto totoka tuatahi i mua i te 40 tau te pakeke .

Ko ngā tohu e kitea whānuitia ana ko:

• Te Thrombosis Utauta Hōhonu (DVT): Ka pupuhi pea te waewae, ka whero, ka mamae, ā, ka mahana ina pā atu.
• Te Pukupuku Pūkahukahu (PE): Ka puta pea he poto ohorere o te manawa, he mamae o te uma (ina koa i te wā e manawa ana), he tere o te manawa, he maremare (i ētahi wā he toto), me te poto o te manawa. He āhuatanga tēnei e hiahia ana kia rongoatia wawetia.

Haunga ēnei, ahakoa he onge, i roto i ngā uaua roro , i roto rānei i ngā uaua pukuTērā pea ka puta he toto totoka.

He aha i puta ai tēnei ngoikoretanga o te antithrombin?

I te nuinga o te wā, ko te take o tēnei mate he ira tuku iho , arā, he mea i riro mai i ō tātou mātua.

• Te Hurihanga Ira: Ka puta te ngoikore o te Antithrombin i roto i te hunga he whakarerekētanga (whakarerekētanga) kei roto i te ira e kiia nei ko te `SERPINC1`. Ka tohutohu tēnei ira i te tinana ki te hanga antithrombin.
• Tuku Iho: Ka taea e koe te tuku iho i tēnei whakarerekētanga ira mai i tētahi o ngā mātua. Mena koinā, e 50% te tūponotanga ka pāngia koe e te mate. Ahakoa he kōtiro, he tama rānei. Heoi, ko ngā pēpi e tuku iho ana i tēnei whakarerekētanga ira mai i ngā mātua e rua, kāore e ora. He tino onge tēnei.

Ko te mea nui, ehara i te mea ka puta he toto totoka i te hunga katoa e pāngia ana e tēnei whakarerekētanga ira. Tērā pea ka ora tonu ētahi tāngata i ō rātou oranga katoa me te kore he raruraru.

Me pēhea te mōhio o ngā tākuta ki tēnei?

Mena kei a koe ēnei tohu, kei te mōhio rānei koe kei tētahi o tō whānau kei te pāngia e tēnei mate, he mea pai kia kite i tētahi tākuta kia tirohia koe. Ko te tikanga, ko ēnei te mahi a te tākuta:

• Whakamātautau tinana: Ka tirotirohia tō tinana.
• Hītori hauora: Ka pātaihia koe mō ō tohumate, me te mea kua pāngia tētahi o tō whānau e ngā raruraru ōrite.
• Whakamātautau toto: Ko te mea nui ko te whai i tētahi whakamātautau toto motuhake hei tirotiro i te taumata o te antithrombin i roto i tō toto.

Ko ēnei whakamātautau anake te huarahi hei whakaū mēnā kei te noho tēnei āhuatanga, kāore rānei.

He aha tāu e mahi nei hei maimoatanga?

Ko te maimoatanga e whakawhirinaki ana ki te mea he toto totoka tōu.

• Mena he toto totoka tōu: Ka whakatau pea tō tākuta ki te tīmata i te tango i tētahi rongoā whakaiti toto . Ko te warfarin te nuinga o te wā (kua rongo pea koe i tēnei ingoa ko Coumadin). Tērā pea ka roa pea tēnei mō ētahi marama, ka roa pea mō te wā katoa.
• Mena kāore anō kia pāngia koe e te toto totoka: Ahakoa he ngoikore tō antithrombin, ki te mea kāore anō kia pāngia koe e te toto totoka, kāore koe e hiahia ki te tango tonu i ngā rongoā whakangawari toto. Heoi, i ētahi wā (hei tauira, i mua i te pokanga nui) ka hoatu pea mō te wā poto.
• I te wā e hapu ana: I te mea kei waenganui i te 3% me te 50% o ngā wāhine hapu me tēnei mate ka pāngia e te toto totoka i te wā e hapu ana, ka whakatau pea te tākuta ki te werohanga i te rongoā e kīia nei ko te 'Heparin' hei ārai i te hanganga o ngā toto totoka i taua wā.

Me pēhea taku tiaki i ahau anō? (I a au e whiwhi ana i te maimoatanga)

Mena kei te tango koe i ngā rongoā whakaiti toto pēnei i a Warfarin, i a Heparin rānei, he mea tino nui kia tangohia te rongoā kia rite ki tā te tākuta i tohutohu ai.Me whakarite hoki kia tae atu koe ki ia wā hui ki te tākuta.

Nā te mea he mōrearea toto tēnei rongoā, me tirotiro tonu e tō tākuta kei te whiwhi koe i te horopeta tika. Ka whakamahia ngā whakamātautau toto pēnei i te whakamātautau `Prothrombin Time` (PT) hei tirotiro mēnā he tika te horopeta o te Warfarin.

Mā te whakahaere tika i te horopeta o te rongoā i tēnei ara, ka taea te ārai i ngā toto totoka kino, me te toto koretake hoki.

He aha taku e taea ai te whakaiti i te mōrearea o te toto totoka?

Mena he ngoikore tō antithrombin, he maha ngā mea ka taea e koe te mahi hei whakaiti i tō tupono ki te toto totoka:

• Kaua e tango i ngā pire ārai whānau: inā koa ko ērā kei roto ko te estrogen. Kōrero ki tō tākuta mō tēnei.
• Āta karohia te rongoā homoni: Ka taea hoki e ētahi rongoā homoni e tangohia ana i muri i te paheketanga te whakanui ake i te mōrearea.
• Kaua e noho roa i te tūranga kotahi: Ina koa kei te haere tawhiti, kei te mahi rānei i te wāhi kotahi mō te wā roa rawa, whakatika ake i te iti rawa i ia rua hāora ka hikoi haere me te rūrū i ō waewae.
• Kaua e momi hikareti, kaua hoki e whakamahi i ngā hua tupeka: He tino kino te momi hikareti ki ngā uaua toto, ā, ka nui ake te tūponotanga o te toto totoka.
• Kia mau ki te taumaha hauora: Ko te momonatanga tētahi atu take o te toto totoka.

Hei tāpiritanga, ko ngā mea pēnei i te whara nui, te pokanga, te haputanga, te whānautanga, me te koroheketanga ka whakanui ake i tō tupono ki te toto totoka. Mena me pokanga koe, kei te hapu rānei koe, kōrero ki tō tākuta mō tō āhua. Tērā pea ka hoatu e ia he werohanga antithrombin motuhake hei werohanga ā-uaua (IV), ki te hiahiatia.

He ara kei reira hei ārai i tēnei āhuatanga kei puta?

Engari, nā te mea he mate ira tēnei, kāore he huarahi hei ārai i te ngoikore o te antithrombin tuku iho . Kāore e taea e tātou te whakarerekē i ngā ira i riro mai i ō tātou mātua. Heoi anō, tera ētahi mea ka taea e tātou te mahi hei whakaiti i te tūponotanga o te toto totoka.

He aha ngā mea hei tumanakohia mēnā he ngoikore tō antithrombin?

Tata ki te kotahi i roto i te toru o ngā tāngata e pāngia ana e tēnei mate ka pāngia e te toto totoka i te pakeketanga.

• Pokanga me te kore e nekeneke: Mena kei te pokanga koe, ā, kāore e nekeneke mō te wā roa (hei tauira, me noho tonu koe ki te moenga), he nui ake te mōrearea o te whakawhanake i ngā toto totoka.
• Te koroheketanga: Ka paku piki ake anō hoki tēnei mōrearea i te pakeketanga.
• Hapūtanga: Tērā pea ka puta he toto toto rerekē i te hunga e kore e whai antithrombin i te wā e hapū ana, i muri rānei i te whānautanga, nō reira me aro nui ki tēnei.

Kia pēhea te roa o tēnei āhuatanga?

Nā te mea he mate ira tēnei, i whānau mai koe me tēnei mate. He mea ka mau tonu mō te wa katoa. Arā, kāore e taea te whakaora katoa. Engari, ki te whakahaeretia tika, ka iti ake ngā raruraru ka taea e koe te noho me te kore e raru.

He aha te tirohanga mō tēnei āhuatanga?

Ko tō tirohanga kei runga i te mea kua pāngia koe e te toto totoka. Ka taea e te tango rongoā whakangawari toto te āwhina i te aukati i te hanganga o tētahi atu toto totoka. Heoi, he mea nui kia tangohia te rongoā kia rite ki tā tō tākuta e tohutohu ana ki a koe, i te horopeta tika, me te roa o te wā tika.

He aha te mea me tino tupato ahau?

Mena he ngoikore tō antithrombin, he mea nui kia mōhio koe ki ngā tohu whakatūpato o te `DVT` (he toto totoka i te waewae) me te `PE` (he toto totoka i te pukahukahu) kia tere ai te rapu āwhina.

• Ngā tohu o te DVT: pupuhi, mamae, whero, me te mahana o te waewae kotahi ina pā (kotahi noa iho te nuinga).
• Ngā Tohu o te PE: Te poto ohorere o te manawa, te mamae o te uma (ka kino ake i te wa e manawa ana), te tere o te manawa, te poto o te manawa, te maremare (i ētahi wā he toto).

Mena kei te tango koe i ngā rongoā whakaiti toto (hei tauira, Warfarin), kia tūpato ki ēnei mea e whai ake nei nā te mea he tūponotanga kei te toto koe:

• Kia tino tupato i te whakamahi i ngā patu koi (maripi, heu, me ētahi atu)
• Āta karohia ngā hākinakina ka whara ai koe (hei tauira, te whutupōro, te mekemeke). Ki te kore, mauria he taputapu tiaki tika.
• Ki te kore te toto e mutu ahakoa i tētahi patunga noa iho, ki te puta rānei he marō mōu, kāore he take, me kōrero ki tō tākuta.

Āhea ahau me kite i te tākuta?

Ki te whakapae koe kei a koe te DVT, me toro atu ki te tākuta tonu. He mea nui kia tere te rongoā i te DVT, nā te mea ka pakaru te toto totoka i te waewae ka haere ki ngā pukahukahu, ka puta he PE.

Mena kei te tango koe i ngā rongoā pēnei i te Warfarin, me kōrero tonu atu ki tō tākuta mēnā ka hinga koe, mēnā rānei he toto rerekē tōu (hei tauira, mai i tō ihu, i tō kapia, i tō tūtae rānei).

Āhea koe me haere ki te Wāhanga Maimoatanga Ohotata (ETU) ?

I roto i tēnei āhuatanga , me haere tonu koe ki te Wāhanga Maimoatanga Ohotata (ETU) o te hōhipera:

• Mena kei a koe ngā tohu o te `Pulmonary Embolism (PE)` (pēnei i te poto o te manawa, te mamae o te uma).
• He aha mēnā kei te whakaaro koe kei a koe ngā tohu o te DVT , engari kāore e taea e koe te whakapā atu ki tō tākuta?
• Mena kei te tango koe i ngā rongoā whakangawari toto, ki te pā tō mahunga, ki te ruaki toto koe, ki te kore rānei e taea e koe te aukati i te toto mai i te patunga.

He āhuatanga ohorere ēnei e morearea ai te ora, nō reira kaua e whakaroa.

He aha ngā pātai nui me pātai atu e au ki taku tākuta?

Kia mōhio koe kei a koe tēnei mate, ka taea e koe te pātai atu ki tō tākuta i ēnei pātai:

• Me tango e au te Warfarin, tetahi atu rongoā whakaiti toto rānei? Kia pēhea te roa me tango e au?
• He mea pai kia whakamātauria ētahi atu o tōku whānau (ngā mātua, ngā tuākana, teina, tamariki) mō te ngoikore o te Antithrombin?
• He aha ngā mahi whakakori tinana ka taea e au te mahi haumaru me tēnei mate?
• He aha ngā mea motuhake me mōhio ahau i mua i taku haputanga?

Pātaihia ēnei pātai kia pai ake ai tō māramatanga ki tō āhuatanga.

Hei whakamutunga, ngā mea hei maumahara māu (Karere hei tango ki te kāinga)

Nā te mea he mate ira te ngoikore o te Antithrombin, kāore e taea e tātou te whakahaere. Heoi, mā te mōhio ki tēnei mate me te mahi i ngā mahi e tika ana, ka taea e koe te ora i te oranga hauora ake.

Ko te mea nui kia mōhio koe me tō whānau ki ngā tohu whakatūpato o te DVT me te PE, kia taea ai e koe te kite wawe i te hē, ā, kia tere ai te rapu maimoatanga.

Mā te whakahaere i tō taumaha, te noho kaha (te whakakori tinana auau), me te karo i te kai paipa ka āwhina i a koe ki te whakaiti i tō tupono ki te whakawhanake i ngā toto toto kore e hiahiatia. Mā tēnei, ka taea e koe te whakahaere i te pānga o tēnei mate ki tō oranga ki tētahi taumata. Kōrero ki tō tākuta i ia wā, ā, kia ata whai i ana tohutohu. Kaua e manukanuka, ehara i te mea ko koe anake!

te korenga o te antithrombin, te toto totoka, te DVT, te embolism pūkahukahu, ngā mate ira, ngā rongoā whakangawari toto, warfarin, heparin