He HER2-Negative tō mate pukupuku ū? Me kōrero māmā noa iho tēnei! (HER2-Negative Mate Pukupuku Ū)

He uaua ki te whakapuaki i ō kare ā-roto ina kī mai tō tākuta he mate pukupuku ū tōu. He mea noa te maha o ngā pātai me ngā mataku e puta ake ana ki roto i tō hinengaro. Engari ko tētahi o ngā mea nui hei āwhina i a koe i tēnei haerenga uaua ko te mārama ki te āhua tuturu o tō mate pukupuku. He mea tino nui te mōhio ki te wāhanga o te mate pukupuku, tōna momo, tōna rahi, me ētahi o ngā pūmua i roto i ō pūtau mate pukupuku hei whakatau i te maimoatanga.

He aha te HER2-Negative?

Kia mārama tātou ki tēnei. He rite ngā pūtau o roto i tō tātou tinana ki ngā whare iti. He 'pūihi' motuhake ā ēnei whare e whiwhi karere mai i waho. I roto i te rongoā, ka kiia ēnei he kaiwhakawhiwhi. Mai i ēnei pūihi ka whiwhi te pūtau i ngā karere pēnei i te 'tipu' me te 'wehe'.

Ko te HER2 (Human Epidermal Growth Factor Receptor 2) tētahi o ngā pūihi motuhake. Ka āwhina te HER2 ki te whakahaere i te tipu o ngā pūtau hauora. Heoi, i ētahi wā, ka nui rawa te mahi a ngā pūtau matepukupuku ki tēnei pūihi HER2, he nui atu i te mea noa. Kātahi ka whiwhi te matepukupuku i tētahi karere tonu e kī ana kia 'tipu', ā, ka tīmata te matepukupuku ki te horapa tere. Ka kiia tēnei āhuatanga he HER2-Positive .

Nō reira, ki te kī mai tō tākuta he HER2-kino tō matepukupuku ū , ko te tikanga kāore he pūihi HER2 tāpiri i roto i ō pūtau matepukupuku. He māmā noa iho, kāore he take nui o tō matepukupuku hei tere ake i tōna tipu.

Me pēhea koe e mōhio ai ki te tūnga HER2 o tō matepukupuku?

He rite tonu ngā tohu o ngā mate pukupuku HER2-kino me ngā mate pukupuku HER2-pai. Kāore e taea e tō tākuta te kī atu ki a koe ko tēhea momo kei a koe mā te tirotiro noa i a koe. Me tango e ia he tauira iti o tō pukupuku (biopsy) ka whakamatautauria. Mā tēnei whakamātautau ka kitea te nui o te pūmua HER2 kei roto i ngā pūtau mate pukupuku.

Me titiro tātou ki tētahi mea nui atu i a HER2 anake!

Ehara i te mea ko te HER2 anake te mea e pā ana ki te tipu o te mate pukupuku. E rua atu ngā momo kaiwhakawhiwhi (ngā kaiwhakawhiwhi homoni - HR) i roto i tō tātou tinana e pāngia ana e ngā homoni.

• Ngā Kaiwhakawhiwhi Estrogen (ER)
• Ngā Kaiwhakawhiwhi Progesterone (PR)

Mena kei ngā pūtau matepukupuku ēnei kaiwhakawhiwhi, ka taea e ngā homoni estrogen me te progesterone te āwhina i te tipu o te matepukupuku. Ka kōrero ngātahi ngā tākuta mō ēnei kaiwhakawhiwhi katoa. Ko te tikanga o tēnei ka taea te wehewehe anō i tō matepukupuku HER2-kino ki ngā momo e rua:

1. HR-Pai / HER2-Kāore: Ko te tikanga o tēnei, kāore te matepukupuku e pāngia e te HER2, engari e pāngia ana e ngā homoni. Koinei te momo matepukupuku ū e tino kitea ana .

2. HR-Kino / HER2-Kino: Ko te tikanga tēnei kāore te mate pukupuku e pāngia e te HER2, e ngā homoni rānei. Nā te mea kua ngaro katoa ēnei kaiwhakawhiwhi e toru (HER2, ER, PR), ka kiia hoki tēnei momo he Toru Kino .

Mā te mōhio ki ēnei āhuatanga katoa ka āwhina i a koe me tō tākuta kia mārama ake te whanonga koiora o tō matepukupuku, ā, mā tēnei ka āwhina i a koe ki te whiriwhiri i te kōwhiringa maimoatanga tino tika, tino whai hua hoki māu.

He aha ngā maimoatanga mō te mate pukupuku HER2-kino?

Nā te mea he HER2-kino tō matepukupuku, kāore koe e whiwhi i te rongoā arotahi, e arotahi ana ki te pūmua HER2. Nā te mea me whai pūnga HER2 ngā rongoā ki ngā pūtau matepukupuku kia mahi ai. Engari, ka whiriwhiria ētahi atu maimoatanga i runga i te wāhanga o tō matepukupuku me te mea he tairongo ki ngā homoni.

• Pokanga me te irahiko: Mena ka kitea wawe te mate pukupuku, ka taea e te pokanga te tango katoa. Tērā pea ka tūtohutia te rongoā irahiko i mua atu, i muri rānei i te pokanga.

• Whakaora Endocrine/ Homone : He mea tino nui tēnei maimoatanga mēnā he HR-Positive/HER2-Negative tō matepukupuku. Mā te whakaiti i ngā taumata o ngā homoni pērā i te estrogen i roto i te tinana ka mahi. Ina ngaro ngā homoni, ka ngaro te karere a ngā pūtau matepukupuku kia tipu, ā, ka memeha pea te matepukupuku, ka mutu rānei te tipu.

• Te rongoā matū: Ka taea te whakamahi i te rongoā matū me te rongoā homoni mō ngā mate pukupuku HR-pai / HER2-kino. Ka whakawhirinaki tēnei ki ngā āhuatanga pēnei i te wāhanga me te nui o te mate pukupuku, tō tau, me tō hauora whānui. I ētahi wā ka nui ake ngā pānga taha o te rongoā matū i ngā painga, nō reira he mea nui kia kōrero koe ki tō tākuta mō te mea pai mōu.

• Whakaora Ārai Mate: Mena kua toru ngā hua kino o tō mate pukupuku, ā, kua horapa haere, ā, kei roto tētahi atu pūmua e kiia nei ko te PD-L1, he kōwhiringa pea tēnei maimoatanga. Ka mahi mā te whakaoho i tō ake pūnaha ārai mate ki te whawhai ki te mate pukupuku.

Te Tirohanga me te Matapae

Ko te mea nui mō te mate pukupuku o te ū ko te kimi i mua i te horapa ki ētahi atu wāhanga o te tinana. Mena kei te ū tō mate pukupuku HER2-kino, he tino teitei te reiti oranga whanaunga mō ngā tau e 5. He pono rawa tēnei mena he HR-pai tō mate pukupuku.

He uaua ake te rongoā i ngā mate pukupuku toru-kino nā te mea kāore e aro ki te rongoā homoni, ki ngā rongoā HER2 rānei. Ka taea hoki e rātou te kaha ake te whakaeke.

Kei raro nei ngā reiti oranga whanaunga mō ngā tau e 5 i runga i te taumata o te mate pukupuku. He toharite noa iho ēnei, kia maumahara he rerekē pea tō āhua ake.

Kaua e mataku ki ēnei tau. He toharite noa iho ēnei mai i ngā mano tini tāngata. Ka whakawhirinaki tō tirohanga takitahi ki ngā āhuatanga maha, tae atu ki te urupare a tō tinana ki te maimoatanga me tō hauora whānui. Nō reira, kia tuwhera ki tō tākuta mō tō āhua me ngā whakamātautau tāpiri e hiahiatia ana e koe.