He momona anō hoki tō ate? Me ako tātou mō te MASH (Metabolic Dysfunction-Associated Steatohepatitis)!

Kua rongo kē koe i tētahi mate e kohia ai te ngako i roto i te ate? I ētahi wā, ka taea e tēnei āhuatanga te kino rawa atu, kāore he tohu nui. I tēnei rā, ka kōrero tātou mō tētahi o aua mate ka pā puku ki tō tātou ate. Ko te MASH (Metabolic Dysfunction-Associated Steatohepatitis) tēnei.

He aha rawa te MASH (Metabolic Dysfunction-Associated Steatohepatitis)?

Ki te whakarapopoto, ko te MASH he āhua e nui rawa ai te ngako o tō ate, ka puta ai te mumura , he āhua e rite ana ki te whara. Whakaarohia pēnei: ​​ina whara koe, ka whero te wāhi, ka pupuhi, ka wera, ā, ka pērā anō te āhua i roto i te ate. Ko te ingoa mō tēnei āhua ko NASH (non-alcoholic steatohepatitis).

Ko tēnei mate, e kiia nei ko te MASH, he wāhanga o tētahi rōpū whānui o ngā mate ate e kiia nei ko te MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease). Ka puta tēnei i te kohikohinga o te ngako i roto i te ate mō ngā take ehara i te inu waipiro.

Ko te mea nui, ki te kore tēnei e rongoatia tika, ka roa pea ka arahi ki ngā āhuatanga pēnei i te cirrhosis, ka whakapakeke, ka whara te ate, ka pāngia rānei e ngā mate kino pēnei i te mate pukupuku ate. Nō reira, he mea nui kia mōhio ki tēnei.

He aha ngā tino take o te MASH? Ko wai kei te mōrearea?

Ko te tino take o te MASH ko te nui rawa o te ngako e kohia ana i roto i te ate, ka kino ai te ate, ka puta ai te mumura. Ka puta pea tēnei āhuatanga ina he raruraru kei roto i te pākia o te huka me te ngako i roto i tō tātou tinana. Me titiro tātou ki ngā tino take me ngā āhuatanga mōrearea e pā ana ki tēnei:

• Te momona rawa, te taumaha rawa rānei: He mea nui tēnei.
• Mate huka momo 2: He nui ake te mōrearea o te hunga mate huka ki te pāngia e te MASH.
• Te cholesterol teitei: Ka piki ake te nui o te cholesterol kino i roto i te toto.
• Ngā triglycerides teitei: He momo ngako anō hoki tēnei i roto i te toto. Kāore hoki i te pai te pikinga o ēnei.
• Te toto toto tiketike: Ka kiia e mātou ko te pēhanga.
• Te ātete ki te insulin: Ina kore ngā pūtau o te tinana e aro tika ki te insulin. He āhuatanga tēnei e puta mai ana i mua i te mate huka.

Kia maumahara, ahakoa he taumaha noa tōu, ki te mea he nui tō cholesterol, he toto toto tiketike, he mate rānei pērā i te mate huka, tera pea ka tūpono koe ki te pāngia e te MASH. Nō reira, ki te mea kei a koe tētahi o ēnei āhuatanga mōrearea, he mea whakaaro nui kia toro atu koe ki tō tākuta kia tirohia mēnā kei te pāngia koe e te MASH.

He aha ngā tohu o te MASH? Me pēhea te mōhio ki tēnei?

Anei te raruraru: He maha ngā wā kāore e kitea ngā tohu o te MASH i ngā wāhanga tōmua.Ka āta whanake te mate i roto i ngā tau maha. Ka tīmata noa te puta o ētahi tohu i muri i te kino o te ate. Ina puta mai ngā tohu, ko ēnei pea:

• Ngenge: Te ngenge tonu ahakoa kāore he mahi.
• Te mamae, te kore whakamarie rānei i tō puku matau o runga: Kei te wāhi tonu o te ate.
• Te whakahekenga taumaha kāore i te mārama.
• Te ngoikore o te uaua, te ngaro rānei o te uaua.
• Puku pupuhi, waewae rānei.
• Ina kino rawa te āhua, ka kōwhai ngā kanohi me te kiri (jaundice): Koinei te mea e kīia ana e tātou i ētahi wā he jaundice.

I te mea kāore he tohu i ngā wāhanga tōmua, he mea tino nui kia tirotirohia koe i ia wā, inā koa mēnā he āhuatanga mōrearea tōu pēnei i te momona, te mate huka, te cholesterol teitei rānei. Koinei te wā ka taea e koe te tautuhi wawe i tēnei mate.

He aha atu ngā raruraru ka puta mai i te MASH?

Ki te kore e rongoatia tika te MASH, ka arahi pea ki ngā raruraru kino, ā, i ētahi wā ka morearea te ora. Anei ēnei:

• Te mate ate: He whara tēnei o te ate. Ka roa te wā, ka nui haere te whara, ka hua ake te mate cirrhosis.
• Ātete toto: He āhuatanga tēnei e tino pāngia ai te ate, ā, ka ngoikore tana mahi. He āhuatanga pumau tonu tēnei, arā, he uaua ki te whakakore.
• Te ngoikore o te ate: Ka mutu te mahi tika o te ate. Ka puta ohorere pea tēnei. Ki te puta tēnei, me rapu awhina hauora tonu koe, me whai whakawhitinga ate rānei.
• Matepukupuku ate: Ka whakanui ake te MASH i te mōrearea o te whakawhanake i tēnei momo matepukupuku ate noa.
• Mate ngakau: Ko te hunga whai MASH he nui ake te mōrearea ki te whakawhanake i ngā mate e pā ana ki te ngakau pērā i te mate ngakau me te whiu.

Whakaarohia, ka tīmata katoa i te iti o te ngako i roto i te ate. Koia mātou e mea nei, kaua e warewarehia te mea iti rawa.

Me pēhea te tautuhi a ngā tākuta i te mate MASH?

Nā te mea kāore te MASH e puta mai i te tīmatanga, he maha ngā mahi hei mahi māu hei tautuhi i tōna mate. Ka tirotirohia e te tākuta tō tinana i te tuatahi. Kātahi ka pātai atu rātou ki a koe mō ētahi atu āhuatanga hauora ka piki ake ai tō tupono ki te whakawhanake i te MASH (hei tauira, te mate huka, te cholesterol). Hei tāpiri, ka mahia pea e rātou ēnei whakamātautau e whai ake nei:

Ngā whakamātautau toto

Ka whakahau tō tākuta i ngā whakamātautau toto hei tirotiro mēnā he kino, he mumura rānei te ate. Kei roto pea i ēnei:

• CBC (Tau Toto Katoa): Te tatau toto katoa.
• BMP (Paewhiri Pūnaha Pūnaha Taketake): Whakamātautau tukanga pūnaha taketake.
• Paewhiri ngako: Tirohia ngā taumata ngako pēnei i te cholesterol me te triglycerides.
• Hemoglobin A1C: He whakamātautau hei aromatawai i te whakahaeretanga o te mate huka.

Ngā whakamātautau whakaahua

Ka taea e ēnei whakamātautau te tango pikitia (whakaahua) o roto o tō ate. Ka tirohia e tō tākuta ēnei pikitia hei tirotiro i ngā huringa o tō ate e pā ana ki te tūnga MASH. Tērā pea ka mahia ēnei whakamātautau:

• Matawai CT (matawai CT - Matawai Tomography Rorohiko)
• Matawai Ultrasound
• FibroScan®: He momo ultrasound motuhake tēnei e ine ana i te pakari o te ate. Mā tēnei ka taea te whakaatu i te mate pukupuku ate.
• Te elastography aukume me te wāhanga ngako kiato proton (MRE-PDFF): Ka taea e tēnei te ine tika i te nui o te ngako i roto i te ate.

Te koiora ate

I ētahi wā, me tango pea e tō tākuta tētahi tauira iti o te kiko mai i tō ate e kiia nei ko te koiora ate. Ka tirohia e te tākuta mate te tauira i raro i te karuārai hei tirotiro mō te ngako, te mumura, me te whara i roto i te ate. Ko te koiora ate te huarahi pai ki te tautuhi tika i te MASH.

Hei tāpiritanga, ka whakahaerehia pea e tō tākuta ētahi atu whakamātautau hei whakatau mēnā he mate ate kē atu ō tohu.

He aha ngā maimoatanga mō te MASH?

Ko te arotahi o te maimoatanga mō te MASH ko te whakapai ake i te hauora o te pūnaha io o tō tinana, me te ārai i ngā kino atu ki tō ate. Tērā pea kei roto i tō mahere maimoatanga:

Ngā huringa āhua noho

Hei whakahaere i te MASH, he mea nui kia kai hauora, kia kaha te tinana, kia whakaitihia hoki te taumaha. Tērā pea ka tūtohu tō tākuta i ngā huringa āhua noho pēnei i:

• Kai i tētahi kai hauora: Ko tētahi mahere kai pai hei āwhina i te whakahaere i te MASH ko te kai Mediterranean , arā, he kai iti-warowaihā . He māmā noa iho, kai i ngā huawhenua, i ngā hua rākau, i ngā pīni, i ngā witi katoa muka, i ngā pūmua kounga pai (ika, heihei), me ngā ngako hauora (āwōkātō, hinu oriwa, nati). Me whakaiti e koe ngā mea reka, ngā kai momona, me ngā kai tere i te mea ka taea.
• Te kaha o te tinana: kia kotahi te iti rawa i te wikiNgāna kia 150 ki te 300 meneti te roa o te whakakori tinana ā-hauora, he āhua ngāwari te kaha. Hei tauira, ko te hikoi tere, te oma, te eke pahikara, me te kaukau.
• Āta karohia te waipiro: Ahakoa he iti noa te waipiro ka pāngia tō ate, nō reira he mea nui kia kaua e inu waipiro.

Rongoā

Tērā pea ka tohua e tō tākuta ētahi rongoā hei āwhina i te whakaiti i ngā tohumate, pērā i te whara, i puta mai i te MASH. Hei tauira:

• Resmetiron (Rezdiffra®): Tērā pea ka āwhina tēnei rongoā ki te whakaiti, ki te whakakore rānei i te whara o te ate i puta mai i te MASH. Koinei anake te rongoā kua whakaaetia e te U.S. Food and Drug Administration (FDA) hei rongoā i te MASH i ngā wāhanga 2 me te 3 o te fibrosis.
• Ngā kaiwhakaoho GLP-1: Ka āwhina ēnei rongoā ki te whakaiti i te mumura me te ngako i roto i te ate. Ko ētahi tauira ko te liraglutide (Victoza®, Saxenda®), te semaglutide (Ozempic®, Wegovy®), me te tirzepatide (Mounjaro®, Zepbound®). He maha hoki ngā wā ka whakamahia ēnei hei rongoā i te mate huka.

Hei tāpiritanga, ka tohua pea e tō tākuta ētahi atu rongoā, tāpiringa rānei. Hei tauira, ka tūtohutia pea he rongoā mate huka e kiia nei ko te pioglitazone (Actoplus Met XR®) he tāpiringa rānei pēnei i te huaora E.

Kei te whakahaerehia e ngā kairangahau ngā whakamātautau haumanu hei kimi i ngā rongoā hou mō te MASH. Ka taea e koe te kōrero ki tō tākuta mō te āheinga ki te whai wāhi atu ki tētahi whakamātautau pēnei.

Pokanga whakaiti taumaha (Pokanga Bariatric)

Mena he tino momona rawa koe, ā, he nui te mate ate, ko te pokanga whakaiti taumaha (pokanga bariatric) tētahi atu kōwhiringa maimoatanga. Mā te pokanga ringaringa puku (tango i tētahi wāhanga o te puku) te pokanga bypass puku rānei (whakaiti i te puku) ka puta mai ēnei painga:

• Ka āwhina ki te whakaiti i te taumaha o te tinana.
• Ka taea te whakaiti i te kino o te ate i puta mai i te MASH ki tētahi taumata, ā, tera pea ka taea te whakakore.
• Ka tino whakaiti i te mōrearea o te whakawhanake i te cirrhosis, te mate pukupuku ate, me te hiahia ki te whakawhitinga ate.

Ka taea te whakaora katoa i te MASH?

Kāore e taea te rongoā i ngā wā katoa te MASH. Heoi, ki te kitea wawe te mate, ā, ka tīmata wawe te maimoatanga, ka taea te whakakore, te ārai rānei i te kino haere. Ko te tikanga o tēnei he nui te tūponotanga ka taea te ārai i ngā kino atu ki te ate.

Kia pēhea te roa e ora ai te tangata whai MASH?

Ko te roanga o tō oranga ka whakawhirinaki ki te nui o te kino kua pā ki tō ate e te MASH. Mēnā ka kitea te mate, ā, ka rongoātia i te wā wawe, ka taea e te nuinga o te tangata te noho noa.Heoi, i te whanaketanga o te mate ki ngā wāhanga tino kino, ka piki ake te mōrearea o te mate wawe mai i ngā raruraru pēnei i te ngoikore o te ate me te mate pukupuku ate. Heoi anō, ka taea e te maimoatanga te whakaroa i te whanaketanga o te mate me te whakapai ake i te kounga o te oranga. Ko te tīmatanga wawe o te maimoatanga te huarahi pai ki te whakatutuki i ngā hua pai rawa atu.

Āhea ahau me toro atu ki te tākuta?

Mena kei te ngenge tonu koe, kei te mamae, kei te koretake rānei te taha matau o runga o tō puku, kei te pāngia rānei koe e ngā tohu pēnei i te hekenga taumaha kāore i te mārama, he mea nui kia toro atu koe ki te tākuta. He tohu pea ēnei kei te hē tetahi mea o tō ate. Ka whakahaerehia e tō tākuta he whakamātautau hei tirotiro mēnā he MASH, he mate ate rānei.

Kia maumahara, ko ētahi āhuatanga hauora, pērā i te momona me te mate huka momo 2, ka whakanui ake i tō tupono ki te whakawhanake i te MASH. Mena kei a koe tētahi o ēnei āhuatanga, ka tirotirohia e tō tākuta te mahi a tō ate i ia wā.

Hei whakamutunga, ko ngā mea tino nui me maumahara koe

Ina whiwhi koe i te tātaritanga mō te MASH (metabolic dysfunction-associated steatohepatitis), tera pea ka tino ohorere koe, ka mataku hoki. Mena kei a koe ngā āhuatanga pēnei i te momona, te toto toto tiketike, te cholesterol tiketike rānei, tera pea ka whakaaro koe, "Nāku te take o tēnei?"

Engari kia maumahara ki tētahi mea. Kāore tētahi o ēnei mate, tae atu ki te MASH, he he nāu. Ka arotahi tō rōpū hauora ki te wā o nāianei, ehara i te wā o mua. Mā rātou koe e whakamārama ki ngā mahi ka taea e koe te mahi hei whakahaere i te MASH. Ā, ka noho tahi rātou me koe i ia taahiraa o te ara. Nō reira kaua e wehi.

Ko te mea nui ko te mōhio ki ngā tohu, me whai i ngā whakamātautau hauora tika mēnā he āhuatanga mōrearea, me te whai i ngā tohutohu hauora. Kātahi ka taea e tātou te whakaora i tō tātou ate i tēnei hoariri puku.

` MASH, ate momona, cirrhosis, mate pukupuku ate, mate huka, momona nui, cholesterol