Kia tūpato tātou ki te Primary Biliary Cholangitis (PBC), he mate puku e pā ana ki te ate.

He maha ngā wā ka ngenge koe, ka mākūkū rānei, kāore he take? I ētahi wā, kāore pea tātou e aro nui ki ēnei mea hei mea noa i roto i ō tātou oranga o ia rā. Heoi, he tohu whakatūpato pea ēnei i ētahi wā nō roto i ō tātou tinana. Ina koa, koinei pea ngā tohu tuatahi o tētahi raruraru ki tō tātou ate. I tēnei rā ka kōrero tātou mō tētahi mate ka pā puku ki te tinana. Ko te Primary Biliary Cholangitis, ko te PBC rānei te whakarapopototanga.

He aha te Primary Biliary Cholangitis (PBC)?

Whakaarohia kei roto i tō ate he pūnaha o ngā ngongo tino angiangi, ririki. He rite ki ngā manga o te rākau e peka ana. Koinei ngā mea e kiia nei e tātou ko ngā awa waikura. Ko te mahi matua o ēnei awa waikura ko te kawe i te wai e kiia nei ko te 'Awa Waikura' i hangaia e te ate i waho o te ate, arā, ki roto i tō tātou pūnaha nakunaku. He mea tino nui tēnei awa waikura ki a tātou, nā te mea ko tēnei awa waikura te mea e āwhina ana ki te whakarewa i ngā ngako i roto i te kai e kainga ana e tātou.

Ināianei, i roto i tētahi mate e kiia nei ko te Primary Biliary Cholangitis (PBC), ka whakaekea hētia e tō tātou ake pūnaha ārai mate ēnei awaawa au. Ka puta te mumura, te pupuhi rānei, i roto i ngā awaawa au. I roto i te wā, ka kino ngā awaawa au i tēnei mumura, ā, ka whakangaro haere i a rātou.

Ka aha rā? Pērā i te paipa wai kua purua, kāore e taea e te au te rere, ā, ka mau ki roto i te ate. Ka tīmata te au kua mau ki te kino i ngā pūtau ate. I te haere tonu o tēnei kino, ka tīmata te hanga kiko whara hei whakakapi i te kiko ate hauora. Ā tōna wā, ka mārō haere te ate, ā, ka heke tana mahi. Ka kiia tēnei mate ko te cirrhosis . I mua, i huaina anō tēnei mate ko te Primary Biliary Cirrhosis.

He tino kino tēnei mate?

He mate haere tonu, he mate mau tonu hoki te PBC. Ko te tikanga, kāore e pai ake i te pō kotahi, ā, ka kino haere pea ngā tohu i roto i te wā. I ngā wāhanga tōmua, kāore pea he tohu e kitea. Heoi, ki te kore e whakahaeretia te mate, ka taea e ia te arahi ki te ngoikore o te ate. I taua wā, ka tūpono pea te ora mēnā kāore he whakawhitinga ate.

Ko wai te mea tino tūpono ka pāngia e tēnei mate?

Ko tētahi mea e kitea nuitia ana ina kōrerohia tēnei mate, he mea tino noa i waenga i ngā wāhine.Ara. Mō ia tāne e pāngia ana e tēnei mate, tata ki te 10 ngā wāhine ka pāngia. He āputa pērā anō.

• He maha ngā wā ka kitea te mate i muri i te 40 tau.
• Waihoki, ki te mea he mate pūnaha ārai mate tō tetahi o tō whānau, ka nui ake pea tō tūponotanga ki te pāngia e tētahi, e tohu ana he hononga ira kei waenganui i a koe.

He aha ngā tohu me ngā raruraru o te PBC?

He tokomaha te hunga kāore e kite i ngā tohu i ngā wāhanga tōmua o te mate. I ētahi wā ka kitea noa iho i te wā e whakamātautauhia ana te toto mō tētahi atu take. Engari i te haere whakamua o te mate, ka tīmata te puta o ngā tohu.

Ngā tohu noa e puta tuatahi mai ana

• Ngenge: Koinei te tohu tino kitea. Ahakoa te nui o te moe, te okioki rānei, kāore te ngenge e memeha haere.
• Kiri mākūkū: Ka pā te mākūkū, inā koa ki ngā kapu o ngā ringa me ngā kapu o ngā waewae. Heoi, ka pā ki ngā wāhi katoa o te tinana. Mō ētahi tāngata, kāore e taea te manawanui ki te mākūkū.

Kāore ēnei tohu e puta i te huarahi kotahi mō te katoa. Mō ētahi, ka puta mai i te tīmatanga tonu o te mate, mō ētahi ia, ka puta mai i muri tata mai.

Ngā raruraru ka puta pea i te whanaketanga o te mate

Ina kore e taea e te au te rere tika, ka tīmata te kohikohi i roto i ō tātou toto. Waihoki, ka puta ngā raruraru nā te mea kāore te pūnaha nakunaku e whiwhi i te au. I te piki haere o ngā koha o te ate, ka nui haere te pēhanga ki runga i ngā oko toto e haere ana i roto i te ate. Ka taea e tēnei te arahi ki ngā raruraru maha. Me titiro tātou ki ēnei i roto i tētahi ripanga.

He aha te tino take o te PBC?

E ai ki tā mātou i kōrero ai i mua ake nei, he mate pūnaha ārai mate te PBC. I roto i ngā kupu māmā, ka whakaekea hētia e te "ope" o tō tātou tinana (te pūnaha ārai mate) ō tātou ake pūtau pai. He rite ki te whakaeke i ō tātou ake iwi whenua, me te whakaaro he hoariri rātou. I roto i te PBC, ka puta tēnei "whakaeke" ki ngā awaawa au i roto i te ate.

Kāore anō kia tino mōhio ngā tākuta he aha tēnei e puta ai, engari e whakapono ana rātou he maha ngā take pea:

1. Te āhuatanga ira: Mena kei roto i te whānau ēnei mate, ka nui ake te tūponotanga ka pāngia hoki ētahi atu.

2. Ngā āhuatanga taiao: Ina uru mai he huaketo, he huakita, he matū rānei ki roto i te tinana, ka tīmata pea te pūnaha ārai mate o te tangata kua pāngia e te ira tangata kia mahi hē.

Me pēhea te tautuhi i tēnei mate? (Tautuhinga)

Ina kōrero koe ki tō tākuta mō ō tohumate, ka tirotirohia koe e ia, ka whakahau hoki i ētahi whakamātautau hei whakaū i te mate.

1. Ngā Whakamātautau Toto: Koinei te whakamātautau tino nui. E rua ngā mea e tirohia ana.

• Ngā paturopi: Tata ki te 95% o te hunga whai PBC he paturopi motuhake kei roto i ō rātou toto e kiia nei ko te Antimitochondrial Antibody (AMA) .
• Ngā whākōkī ate: Ina pakaru te ate, ka piki ake ētahi whākōkī (ina koa ko te Alkaline Phosphatase - ALP ) i roto i te toto.

2. Ngā Whakamātautau Whakaahua: Mena e whakaatu ana ngā whakamātautau toto he PBC, ka tono pea tō tākuta i tētahi matawai hei tirotiro i tō ate me tō pūkahukahu. Ka āwhina hoki tēnei ki te whakakore i ētahi atu take o ō tohu. Ko te matawai ultrasound te whakamātautau tuatahi e mahia ana. Ka taea te mahi i tētahi matawai MRI hei tiki whakaahua mārama ake.Ka taea hoki e koe te kōrero mō tētahi.

3. Kohikohi Ate: I ētahi wā (ina koa mō te hunga kāore he paturopi AMA i roto i ō rātou toto), ka tangohia he wahi iti rawa o te kiko ate ka tirotirohia i raro i te karuārai hei whakaū i te mate me te whakatau i te whānuitanga tika o te kino o te ate.

He aha ngā maimoatanga mō te PBC?

Kāore anō kia kitea he rongoā mō te PBC. Heoi anō, he tino whai hua ngā maimoatanga hei whakaiti i te kino o te ate i puta mai i te mate, hei whakahaere i te haere whakamua o te mate, me te whakahaere i ngā tohu.

Rongoā

• Waikawa Ursodeoxycholic (UDCA): Koinei te rongoā matua mō te PBC. He waikawa au e puta noa ana. Ka āwhina tēnei rongoā ki te tango i te au mai i te ate, ā, ka whakaiti i te kino o te ate. Ka tino whai hua ina tīmatahia i te tīmatanga o te mate.
• Ngā rongoā kē atu: Mō te hunga kāore e pai te urupare ki te UDCA, ka tūtohu pea tō tākuta i ētahi atu rongoā, pērā i te waikawa obeticholic . Hei tāpiri, kei te whakamahia inaianei ngā rongoā hou, pērā i te seladelpar me te elafibrinor .
• Ngā rongoā mō ngā tohu:
• Mō te kiri mākūkū: Ka whakamahia ngā rongoā pēnei i te Cholestyramine, ngā antihistamines, me te rongoā hihi ultraviolet.
• Mō te korenga o ngā huaora: Ka hoatu ngā tāpiringa kei roto ngā huaora A, D, E, me K.
• Mō te ngenge: Tērā pea ka kitea he whakamarie mō ētahi tāngata mā ngā rongoā whakaohooho pēnei i te modafinil.

Pokanga

Mena ka heke tonu te mahi a tō ate, ā, kāore e taea te whakahaere mā te rongoā, ka whakanoho pea tō tākuta i a koe ki te rārangi tatari mō te whakawhitinga ate . He tino angitu ngā whakawhitinga ate mō te PBC. Ka taea e koe te noho i te oranga noa i muri i te whakawhitinga. Ahakoa ka taea e te PBC te hoki ki te ate hou, he tino onge.

He aha ngā mea me mōhio ahau mō te noho tahi me tēnei mate?

He puhoi rawa te whanaketanga o te PBC. E 15-20 tau pea ka tae te mate ki ōna wāhanga whakamutunga. Mēnā ka kitea wawetia te mate, ka rongoatia hoki, ka taea te ārai, te whakaroa rānei i ngā āhuatanga kino o te mate. He maha ngā tāngata e whakahaere ana i ō rātou tohu mā te rongoā, ā, ka ora mō ngā tau maha me te kore e whakararuraru nui i ō rātou oranga o ia rā.

Heoi anō, tera pea ka tere ake te whanaketanga o te mate i ētahi tāngata. Ko te ngenge nui me te nui haere o ngā taumata bilirubin i roto i te toto he tohu pea kei te tere haere te mate.

Ngā mea ka taea e koe te mahi hei tiaki i tō ate

Mā te whai i tētahi momo noho pai me ngā tikanga kai pai ka āwhina i te hauora o tō ate mō te wā roa rawa atu.

• Kati rawa te kai hikareti, te waipiro, me te whakamahi i ngā raau taero koretake.He tino kino ēnei ki te ate.
• Kai atu i ngā kai katoa pērā i ngā huawhenua hou, ngā hua rākau me ngā otaota hei utu mō ngā kai kua tukatukahia, kua tākaihia rānei.
• Whakaitihia te ngako kukū, ā, whiriwhiria ngā kai kei roto ngā ngako kore kukū, ngā ngako "pai" rānei (hei tauira, te āwōkātō, te nati, te hinu oriwa).
• Me whakakorikori tinana i ia rā. Ahakoa he mea ngāwari pēnei i te hikoi, he pai tonu. Mā te whakakorikori tinana e pupuri te kaha o ngā wheua.

Ka taea e te noho me tētahi mate pūmau pēnei te whakararuraru i te hinengaro. Kōrero ki tō tākuta mō ngā huarahi hei whakaiti i tō ahotea tinana, hinengaro, me te kare ā-roto. Rapua he tohutohu mēnā e tika ana. Kia maumahara, he nui ake tō hauora whānui i tēnei mate.