He raruraru kei ngā awaawa o tō ate? Me ako tātou mō te Primary Biliary Cholangitis (PBC)!

Āe, kei te tino ngenge koe, kei te ngenge ahakoa kāore koe e mahi i tetahi mea? I ētahi wā, kei te rite koe ki te rakuraku i tō kiri, kāore he take? I ētahi wā, ahakoa kāore tātou e aro nui ki ēnei, he tohu pea ēnei mō te raruraru o te ate, tētahi o ngā okana tino nui o tō tātou tinana. I tēnei rā ka kōrero tātou mō tētahi mate pēnei e pā ana ki te ate, ā, ahakoa he ahua uaua te ingoa, he ngāwari ki te mārama. Koia te (Primary Biliary Cholangitis) , e mōhiotia ana ko te (PBC) mō te poto.

He aha te Primary Biliary Cholangitis (PBC)? Kia mārama tātou!

Āe, he roa te āhua o tēnei ingoa, kāore? Kia kite tātou he aha tōna tikanga.

Ko te "Cholangitis" he mumura o ō awaawa aukume . Kei te mōhio koe, ko te wai e kiia nei ko te aukume, e hangaia ana i roto i tō tātou ate, ka haere mā roto i tētahi pūnaha o ngā ngongo iti. Ko aua ngongo ka kiia ko ngā awaawa aukume. Ko te tikanga hoki o te "Biliary" he mea e pā ana ki ēnei awaawa aukume. Ko te tikanga o te "Tuatahi" he "taketake" he "tūatahi" rānei.

Kātahi, ina huihuia ēnei mea katoa, ko te tikanga o te Primary Biliary Cholangitis , ehara i te mea nā tētahi atu mate, mate pāwera, ārai rānei, engari nā tēnei mate, ka mumura ngā awaawa o te ate . Nā te mea kāore tēnei mumura e puta hei urupare ki tētahi mea, kāore koe e mōhio āhea ka mutu. Nō reira, he āhuatanga tēnei e haere mārire ana.

I mua i huaina tēnei mate ko te Primary Biliary Cirrhosis nā te mea ka taea e ia te whakapakeke me te whakakōkō i te ate, ka arahi atu ki te mate e kiia nei ko te cirrhosis .

He aha te pānga o (PBC) ki tō tātou tinana?

Whakaarohia, he aha te mea ka tupu mēnā ka mumura tonu tetahi wāhanga o tō tātou tinana? I te nuinga o te wā, ko te mumura rangitahi he wāhanga o te tukanga whakaora. Engari ki te haere tonu tēnei momo mumura mau tonu , kaua e ora, ka tīmata te wāhi ki te hanga i ngā koha.

Koinei te mea ka pā ki ngā awaawa au i roto i tō ate i roto i te PBC. Ka whaiti, ka āraia ēnei awaawa e te whara . Kātahi ka kore e taea e te au i hangaia e te ate te rere tika. Ka tīmata te hoki whakamuri o tēnei au ki roto i te ate. Ina nui haere tēnei au, ka kino ngā pūtau ate, ka puta te mumura i roto i te ate. I roto i te wā, ka whakakapia tēnei kiko ate hauora e te kiko whara. I te mutunga, ka kore e taea e te ate te mahi tika, koinei te mea kua kōrerotia e tātou i mua (cirrhosis) .

He mate kino te PBC?

Ae, he mate mau tonu, he mate haere tonu te Primary Biliary Cholangitis. Ko te tikanga, kāore e pai haere noa, engari ka kino haere i roto i te wā. Kāore e kino haere i te wā kotahi, engari ka kino haere mārire, mā roto i ngā wāhanga rerekē. Tērā pea kāore he tohu i te tīmatanga.

Heoi, ko te mea tino mōrearea mō tēnei, ka taea e ia te arahi ki te ngoikore katoa o te ate , tae atu ki te mate mēnā kāore e mahia he whakawhitinga ate .

Engari, waimarie, kei reira ngā rongoā hei whakaroa i te whanaketanga o tēnei mate . Ā, kāore te katoa e tae ki tēnei wāhanga whakamutunga. Nō reira kaua e manukanuka.

He aha te rerekētanga i waenganui i te (PBC) me te (PSC)?

Kua rongo pea koe i tētahi atu mate e kiia nei ko te Primary Sclerosing Cholangitis, ko te PSC rānei. He tino ōrite ngā mea e rua, engari he iti noa ngā rerekētanga matua.

• I roto i te PBC , ko ngā awaawa aukume anake i roto i tō ate (ngā awaawa aukume intrahepatic) ka pāngia.
• Heoi, i roto i te PSC, ka pāngia ngā awaawa au i roto i te ate me waho hoki o te ate (ngā awaawa i waho o te ate) .
• He rerekētanga anō hoki kei roto i ngā taupori e tino kitea ana ēnei mate e rua.
• Ko te mea nui, ahakoa he rongoā hei rongoā (PBC), kāore anō kia kitea he maimoatanga angitu mō (PSC) .

Ko wai te mea tino tūpono ka pāngia e tēnei mate (PBC)?

Ahakoa he mea miharo pea tēnei, e tekau ngā wā ka nui ake te tūponotanga o ngā wāhine ki te pāngia e te PBC i ngā tāne (10:1) . E ai ki ngā tatauranga i te Hononga o Amerika, e 60 i roto i te 100,000 ngā wāhine e pāngia ana e te mate, ki te whakaritea ki te 15 i roto i te 100,000 ngā tāne.

Ko te nuinga o te tangata ka kitea kua pāngia rātou e te mate i muri i te 40 tau te pakeke. Ko te nuinga o te mate he mate noa i Kōtirana, i ngā whenua Scandinavian, me te raki-mā-rāwhiti o Ingarangi.

Waihoki, ki te mea he mate pūnaha ārai mate tōu, tō tētahi rānei o tō whānau, ka nui ake te tūponotanga ka pāngia koe e te PBC . E tohu ana tēnei he hononga ira pea kei roto.

He aha ngā tohu o te mate (PBC)?

He tokomaha ngā tāngata whai PBC kāore he tohu i ngā wāhanga tōmua. I te whanaketanga o te mate ka tīmata te puta o ngā tohu e pā ana ki ngā awaawa o te ate. Ko ngā tohu tuatahi me ngā tohu tino kitea i roto i ngā tāngata whai PBC ko:

• Te ngenge nui (tata ki te 65% o te tangata)
• Kiri mākūkū (tata ki te 55% o te tangata)

He rerekē te pānga o ēnei tohu ki te katoa. Tērā pea ka pāngia ētahi i te tīmatanga o te mate, ko ētahi i muri mai. Tērā pea ka kaha ake, ka iti ake rānei te kaha i tētahi wāhanga o te mate. Te āhua nei kāore he hononga nui i waenga i te kaha o ō tohu me te whānui haere o te mate. Heoi, e kī ana ētahi rangahau ko te hunga kua pāngia wawetia e ngā tohu kino ka tere ake te whanaketanga o te mate .

He aha ngā āhuatanga uaua o ngā mate o te awaawa o te ate?

I ngā wāhanga tōmua, kāore pea koe e kite he raruraru kei roto i ō awaawa wai. Engari i te haere whakamua o te mate, ka tīmata ngā raruraru maha. Ko te wai awa kāore e taea te rere tika, ko tōKa tīmata te turuturu ki roto i te toto, ka puta ai ngā mate. Waihoki, ina kore e taea e te au te tae tika ki te pūnaha nakunaku, ka whakararuhia hoki te nakunaku . Nā te mea he mea nui te au mō te nakunaku i te kai.

Ā muri ake nei, ka pā anō hoki te whara o te ate ki ngā oko toto e tika ana mā roto i te ate, ka hua ake he mate e kiia nei ko te portal hypertension , arā, ko te toto toto tiketike i roto i aua uaua.

1. Te ngoikore o te mimiti ngako

Ki te kore e nui te au o tō pūnaha nakunaku, kāore e taea e ia te wawahi tika me te mimiti i ngā ngako i roto i tō kai. Ka puta pea ēnei i te ngoikore o te mimitinga o ngā ngako:

• Te cholesterol toto tiketike .
• Ngā putunga ngako i raro i te kiri .
• Tutae momona, mate korere rānei .
• Te whakaheke taumaha .
• Kua heke te nui o ngā huaora wairewa-ngako A, D, E, me K.
• Ko te osteoporosis he mate angiangi wheua e hua mai ana i te iti o te mimiti o te huaora D wairewa-ngako.

2. Te toto toto tiketike o te tomokanga

Ina āraia ngā oko toto e haere ana i roto i te ate nā te whara, ka puta te toto toto tiketike kua whakahuatia ake nei, ko te tikanga ka piki ake te toto i roto i aua uaua me ētahi atu uaua e hono ana ki a rātou. Ka taea e tēnei toto toto tiketike te whakaputa i ēnei āhuatanga:

• Ate nui haere .
• Te whēkau nui .
• Te makariri me ētahi atu mate urutā (te ngoikore o te ārai mate).
• Ngāwari te maru me te toto (iti te nui o ngā pereti toto - (thrombocytopenia) ).
• Te putanga mai o ngā oko toto whero, rite ki te pungawerewere (ngā angiomas pungawerewere) i runga i te mata o te kiri.
• He uaua pupuhi, he uaua here rānei i roto i te korokoro me te puku (ngā uaua pupuhi - varices) .
• Te toto o te puku .
• Te kohi wai i roto i te puku (ascites) .
• Te pupuhi (edema) o te tinana o raro.
• I ētahi wā ka puta te pōhēhētanga hinengaro nā te kohikohinga o ngā paitini i roto i te toto.

He aha ngā take o (PBC)?

I roto i te PBC, ka whakaekea e tō ake pūnaha ārai mate ngā pūtau e whakarārangi ana i ngā awaawa au o tō ate . Me te mea nei kei te kite te pūnaha ārai mate i ēnei pūtau he whakaekenga tauhou. Koinei te mea e kiia nei e tātou he mate ārai mate., ngā mate pūnaha ārai mate rānei. Mō te kore take e kitea, ka whakangaromia e te pūnaha ārai mate ngā pūtau hauora, ā, kāore he mana whakahaere hei aukati. Ko tēnei mumura tonu te take e puta ai ngā koha.

Kāore mātou i te tino mōhio he aha i puta ai ēnei mate ārai-pūnaha. Heoi, te āhua nei he āhuatanga ira kei roto . He maha ngā tāngata e pāngia ana e ngā mate ārai-pūnaha, he hītori whānau tō rātou mō te mate, ā, ka taea e rātou te whakawhanake i ngā momo mate ārai-pūnaha neke atu i te kotahi.

Te āhua nei kei reira anō tētahi āhuatanga taiao . Arā, tera pea he mea kei roto i te taiao ka whakaoho i tēnei mate. He matū pea kei roto i a koe, he mate pāwera rānei.

Me pēhea te tautuhi i te PBC?

Ka pātai tuatahi tō tākuta ki a koe mō tō hītori hauora me ngā tohumate, ka whakahaere i tētahi whakamātautau tinana, kātahi ka tangohia he tauira toto hei tirotiro mō te PBC.

Ko te nuinga o ēnei whakamātautau toto e rapu ana i ngā paturopi motuhake e pā ana ki te PBC, inā koa he paturopi e kiia nei ko te antibody antimitochondrial (AMA) . Ka rapua hoki e rātou ngā whākōkī ate kua teitei ake, inā koa ko te alkaline phosphatase (ALP), e tohu ana i te kino o te ate.

Mena he pai ngā hua o tō whakamātautau mō te PBC, ka hiahia tō tākuta ki te tirotiro i ngā whakaahua o tō ate me tō pūnaha biliary . Mā tēnei ka āwhina ki te whakakore i ētahi atu take o ō tohumate, me te kite i te kaha haere o te mate. I te nuinga o te wā, ka mahia tuatahitia he mea ngāwari pēnei i te ultrasound o te puku. Engari i ētahi wā, ka hiahiatia pea he whakamātautau pēnei i te MRI (magnetic resonance imaging) kia mārama ake ai ngā whakaahua.

Tata ki te 5% o te hunga whai PBC ka kitea he kino te hua o te whakamātautau AMA, engari tera pea he tohu kē atu kei a rātou. Mēnā ka puta tēnei, me tango pea e tō tākuta tētahi wahi kiko iti mai i tō ate (he koiora ate) hei whakaū i te PBC. I te nuinga o te wā ka mahia tēnei i te taha o te moenga mā te wero i tētahi ngira ki roto i tō ate. Ka tukuna te tauira kiko iti i tangohia mai i te ngira ki tētahi taiwhanga hei tirotiro i raro i te karuārai.

He aha ngā maimoatanga mō te Kolangitis Biliary Tuatahi?

Ka whakamahia e ngā tākuta ngā rongoā e whai ake nei hei rongoā mō te PBC:

Rongoā

Kāore e taea te whakaora katoa i te PBC. Heoi, ka taea e ngā rongoā te whakahaere i te haere whakamua o te mate me te whakapai ake i tō āhua .

(Waikawa Ursodeoxycholic - UDCA)He momo waikawa au. Ka āwhina i te tango i te au mai i te ate, me te whakaiti i te kino o te ate. He pai te mahi a tēnei rongoā mō te haurua o te hunga whai PBC, inā koa i ngā wāhanga tōmua o te mate. Mō te hunga kāore e aro ki te UDCA, i ētahi wā ka tūtohu ngā tākuta i tētahi atu momo waikawa au e kiia nei ko te waikawa obeticholic .

Ka taea hoki te rongoā i ō tohumate takitahi mā te whakamahi i ngā rongoā motuhake.

• Mō te kiri mākūkū: ka taea te hoatu i ngā rongoā antihistamine (hei tauira, te diphenhydramine - pērā i te Benadryl®), te rongoā hihi ultraviolet, ngā rongoā aukati waikawa bile pērā i te cholestyramine rānei.
• Ārai i ngā pānga taha pēnei i te korenga o ngā huaora me te osteoporosis: Ka taea e ngā tāpiringa huaora te āwhina.
• Tērā pea ka whai hua ētahi tāngata e ngenge ana i ngā rongoā whakaohooho pēnei i te modafinil.

Pokanga

Ki te kore tō āhua e pai ake mā te rongoā, ā, ka heke tonu te mahi a tō ate, ka whakanoho pea tō tākuta i a koe ki te rārangi tatari mō te whakawhitinga ate . He tino pai ngā hua o te pokanga whakawhitinga ate mō te hunga whai PBC.

Pērā i ngā mate pūnaha ārai mate kē atu, ka taea e te PBC te hoki mai anō i muri i te whakawhitinga ate, engari ka puhoi ake te tere o te whanaketanga o te mate i te wā tuarua. He mea noa te roa o te oranga i muri i te whakawhitinga ate.

He aha ngā mea e tika ana kia tumanakohia e koe ina noho tahi ana koe me tēnei mate?

I te nuinga o te wā, ka puhoi te whanaketanga o te mate kōroke piri tuatahi. Mā te kitenga wawe me te maimoatanga tere ka ārai, ka whakaroa rānei i ngā wāhanga whakamutunga o te mate me ōna raruraru.

Ka taea e te nuinga o te tangata te whakahaere pai i ō rātou tohu mā te rongoā. Heoi, he uaua tonu te rongoā i te ngenge e puta mai ana i te PBC. He maha ngā tāngata e ora ana mō ngā tau maha me te kore e tino whakararuraru i ō rātou oranga o ia rā nā te PBC.

Heoi, kāore te katoa e kitea he PBC i ngā wāhanga tōmua. Ā, ko ētahi tāngata ka pāngia e te momo mate kino rawa atu. Ko ngā tohu pēnei i te ngenge nui me te nui o te bilirubin i roto i te toto ka tohu pea ka tere te horapa o te mate ki te ngoikore o te ate. Ki te tae koe ki taua wāhanga, me whai whakawhitinga ate koe kia ora ai. Engari mō te hunga he PBC ā, kua angitu te whakawhitinga ate, he tino pai te matapae.

Kia pēhea te roa ka taea e koe te ora me (PBC)?

I te nuinga o te wā, e 15 ki te 20 tau te roa ka eke te mate ki te wāhanga whakamutunga.

Ko te wāhanga tuatahi, arā, ahakoa kua whakamātauria koe, ā, kua kitea kei a koe te PBC, tera pea ka noho tonu koe me te kore tohu mō te wā roa. Tata ki te haurua o te tangata ka tīmata te whakawhanake i ngā tohu i roto i ngā tau e rima ki te tekau e whai ake nei.Kia puta ngā tohu, ko te roanga o te oranga he 10 tau te roa. 65% o te hunga kua angitu te whakawhitinga ate ka ora mō ngā tau 10.

Me pēhea taku tiaki i ahau anō ina pāngia ahau e te (PBC)?

Mā te kai me te noho hauora ka āwhina i te ate kia ora tonu mō te wā roa.

Hei tauira:

• Kati te momi hikareti, te inu waipiro, me te whakamahi i ngā raau taero me ngā rongoā i te huarahi hē, i te huarahi rānei hei whakangahau i a koe.
• Kaua e kai i ngā kai kua tukatukahia, kua tākaihia hoki, engari me kai i ngā kai māori.
• Whakaitihia te nui o ngā ngako kukū, ā, kai i ngā ngako hauora kore kukū.
• Me hikoi tere i ia rā. Mā te whakakori tinana e amo taumaha te hauora o te wheua.

He maha ngā tāngata e pāngia ana e te Primary Biliary Cholangitis ka ora mō ngā tau maha, kāore he raruraru nui. Heoi, mā te mate e whanake haere ana, e mate ai i ētahi wā, ka pā kino ki a koe. Kōrero ki tō tākuta mō ngā huarahi hei whakaiti i tō ahotea tinana, hinengaro, me te kare ā-roto . Pātai atu hoki mō ngā whatunga tautoko e āwhina ana i te hunga e noho ana me te PBC. Kia maumahara, he nui ake tō hauora whānui i te mate anake.

Karere Tangohia ki te Kāinga

Ko te Primary Biliary Cholangitis (PBC) he mate mau tonu e pā ana ki ngā awaawa o te ate. E whakaarohia ana he mate pūnaha ārai mate te take. Ahakoa kāore pea e puta ngā tohu i te tīmatanga, ka puta pea ngā tohu pēnei i te ngenge me te mākūkū o te kiri i roto i te wā. I te haere whakamua o te mate , ka arahi pea ki te cirrhosis me te ngoikore o te ate.

Heoi, mā te kitenga wawe me te whakamahi i ngā rongoā pēnei i te (UDCA), ka taea te whakahaere i te mate . Tērā pea ka hiahia ētahi tāngata ki te whakawhitinga ate.

Ko te mea nui ko te rapu tohutohu hauora, me te whai i tētahi momo noho hauora mēnā kei a koe ēnei tohu. Kāore koe i te mokemoke, kaua e wehi ki te kōrero mō tēnei mea, me te rapu āwhina.

` Kolangitis biliary tuatahi, PBC, mate ate, awaawa bile, cirrhosis, pūnaha ārai mate