He rongoā mō te mumura o te puku me te gastritis! Me ako tātou mō ngā aukati papu proton (PPI)!

He maha ngā wā ka pāngia koe e te mamae o te uma, e te mamae rānei o te uma? I kī mai rānei te tākuta ko te "gastritis"? Ko tētahi momo rongoā e tohua ana e ngā tākuta i roto i ēnei momo take ko te `(Proton Pump Inhibitors)`. Mēnā ka tika tā tātou kōrero, tera pea ka kiia hoki e tātou ko te "rongoā mō te gastritis." Nō reira, i tēnei rā ka kōrero tātou mō te `(Proton Pump Inhibitors)`, arā, ko ngā PPI hei whakarāpopototanga.

He aha tātou i hiahia ai ki ēnei PPI? Ka aha te waikawa o te puku?

He kupu ngāwari noa iho, ko ngā `(Proton Pump Inhibitors)` he momo rongoā e whakaiti ana i te nui o te waikawa e hangaia ana i roto i tō puku, arā, te nui o te waikawa puku . Inaianei kei te whakaaro pea koe, "Āe, he aha te take o te waikawa puku? Kāore i te pai." Kāore tēnā i te pono. He mea tino nui te waikawa puku mō ō tātou tinana. Ko tēnei waikawa te mea e āwhina ana i a tātou ki te nakunaku i te kai e kainga ana e tātou. Ehara i te mea koinā anake, engari ka āwhina anō hoki tēnei waikawa puku ki te whakangaro i ngā iroriki kino e kainga ana e tātou me te kai.

Heoi, i ētahi wā ka tīmata ngā raruraru ina nui rawa te pikinga o te waikawa o te puku, ina rere rānei te waikawa ki tētahi wāhi rerekē i tōna tika. He rite ki te kīwaha "Ki te piki, ka paitini te nekita." Koinei te wā ka puta ai ngā mate puku (`mate puku`), e kīia nei e tātou ko ngā "mate puku". Ka puta anō hoki ētahi atu mea pēnei i te mamae o te puku me te reka kawa o te korokoro. Koinei te wā ka āwhina mai ēnei rongoā e kiia nei ko ngā PPI. He mea whakamahi motuhake ēnei mō ngā raruraru roa e pā ana ki te waikawa o te puku.

He aha ngā momo mate e whakamahia ana ēnei PPI?

Ko ēnei momo rongoā (Proton Pump Inhibitors) te nuinga o te wā e whakamahia ana e ngā tākuta hei rongoā i ngā āhuatanga pēnei i te kino me te mumura o ngā wāhanga o tā tātou pūnaha nakunaku, arā, ko ngā whekau me te korokoro, i puta mai i te waikawa o te puku. Kia titiro tātou he aha ēnei:

• GERD, te mate pūkahukahu rānei: He maha ngā wā ka pāngia koe e te mamae o te puku? He reka kawa tō korokoro? Koinei te GERD. I te kīanga māmā, ko te waikawa i roto i tō puku e piki ake ana ki roto i tō korokoro. Ka taea e tēnei te kino i te arai o tō korokoro, e kiia ana ko te erosive esophagitis. Ka mahi ngā PPI mā te whakaiti i te hanga waikawa puku, me te hoatu i te wā ki tō korokoro kia ora.
• Ngā mate puku me ngā mate duodenal: Ko ngā mate puku me ngā mate duodenal he mate puku ka puta mai i te waikawa puku, ka kino pea te arai tiaki o te puku. Ka taea hoki e rātou te whakaputa mate puku i te wāhanga tuatahi o te whekau iti (e kiia nei ko te duodenum). Ka taea e ngā PPI te āwhina ki te whakaora i ēnei mate puku. Hei tāpiri, ko ētahi rongoā whakamamae mamae, inā koa ko ngā rongoā anti-inflammatory kore-steroidal (NSAID), e hono ana ki te pikinga o te mōrearea o te whakawhanake i ngā mate puku. E whakaatu ana ngā rangahau tata ki te 30% o te hunga e tango ana i ngā NSAID ka pāngia e ngā mate puku. Ka taea e ngā PPI te āwhina ki te ārai me te whakaora i ngā mate puku.
• Te mate urutā H. pylori:He momo huakita tēnei ka noho i roto i tō tātou puku. Ka taea hoki e ēnei huakita te whakararu i ngā mate puku. I te rongoā i te mate H. pylori, ka hoatu e ngā tākuta ngā PPI me ngā paturopi. Nā te mea ka whakarerekē ngā PPI i te taumata pH o te puku, ka māmā ake te patu a ngā paturopi i ngā huakita.
• Te mate Zollinger-Ellison: He mate onge tēnei. I roto i tēnei mate, ka puta ētahi momo pukupuku ('pukupuku') i roto i te tinana, ā, ka nui rawa te homoni e puta ai te waikawa o te puku. Ka nui rawa te waikawa o te puku. Ka whakamahia hoki ngā PPI hei rongoā i tēnei mate.

He pēhea te mahi a ēnei rongoā e kiia nei ko ngā PPI? He mea whakamiharo, kāore?

Whakaarohia kei roto i tō tātou puku tētahi "mīhini" iti e hanga waikawa ana. Ka karangatia tēnei mīhini ko te "pamu ATPase hauwai-pāhare pākawa waro", ko te "pamu pūmua" rānei hei whakarapopototanga. Pērā i te papu wai e kukume ana i te wai ki runga, ko tēnei papu pūmua te mea e mahi ana i te tukanga matū e hiahiatia ana hei hanga waikawa puku.

Nō reira, ko tā ēnei `(Ngā Ārai Papu Proton)`, arā, ko ngā PPI , he aukati i te mahi a te papu proton mō te wā poto . Arā, ka "ārai" rātou i te mahi, arā, ka whakararuraru i te mahi. Kātahi ka heke te hanga waikawa o te puku.

Engari kāore tēnei e aukati katoa i te hanga o te waikawa puku, tika? He nui tonu te waikawa e toe ana hei nakunaku i te kai. Ki te tango koe i te PPI mō ngā rā e rima karapīpiti, ka whakaitihia te hanga o te waikawa puku mā te 65%. Ko te 35% o te waikawa e toe ana he nui hei nakunaku i te kai.

He aha ēnei PPI?

Ka taea te hoko i ētahi o ēnei PPI mā te kore whakahaunga (OTC) i te whare rongoā, engari ko ētahi o ngā mea kaha ake me whai whakahaunga mai i te tākuta (Rx anake).

Ngā PPI ka taea te tango me te kore rānei he whakahaunga a te tākuta (OTC me te Rx):

• Esomeprazole (Nexium®)
• Lansoprazole (Prevacid®)
• Omeprazole (Prilosec®)
• Omeprazole/konutai paikāpōnate (Zegerid®)

Ngā PPI e wātea ana me te whakahaunga a te tākuta anake (Rx anake):

• Dexlansoprazole (Dexilant®)
• Pantoprazole (Protonix®)
• Rabeprazole (AcipHex®)

Me pēhea taku tango i tēnei rongoā? Kia hia te nui me tango e au?

Kei roto i te ahua papa, kāpū rānei ēnei rongoā. Ka tangohia mā te waha. Kei roto i ētahi momo kāpū he paura ka taea te whakaranu ki te kai, pērā i te aporo, kātahi ka tangohia. He āwhina nui tēnei mō te hunga e uaua ana ki te horomi pire.

I mua i te tango i te rongoā, me pānui koe i ngā tohutohu kei runga i te kete.Koinei te wā ka whiwhi koe i ngā hua tino tika. Tērā ētahi PPI me tango e koe i te hawhe haora, i te haora rānei i mua i te kai, i te puku kau. Ina tangohia e koe i taua wā, ka whai wā te rongoā ki te mahi i mua i te tīmatanga o te whakaputa waikawa o tō puku i a koe e kai ana.

Ko tō tākuta anake ka taea te kī atu ki a koe te nui o te rongoā e hiahiatia ana e koe ('inenga') me te maha o ngā wā me tango e koe i te rā. Māna e tohu he inenga hei whakahaere i ō tohumate me te iti rawa o te tūponotanga o ngā pānga taha. Mō ētahi tāngata, he nui te tango i te pire kotahi i mua i te parakuihi. Mō ētahi atu, he nui pea te tango i te pire e rua i te rā, i mua i te parakuihi me mua i te tina. I ētahi wā, he nui pea te tango i te pire i ia rā tuarua.

I roto i te wā, me whakaiti pea e koe te horopeta o tō rongoā. Mā tō tākuta koe e tohutohu mō tēnei.

Kia pēhea te roa ka mahi ai ēnei PPI?

I muri i te tango i te rongoā PPI, ka roa pea mai i te 24 hāora ki te whā rā ka puta tōna pānga katoa.

Ki te pāngia koe e te mamae o te uma, e te mamae rānei o te uma, ā, me tere te whakaora, he pai ake te whakamahi i te rongoā antacid (pēnei i a Digene, Acidex) te aukati histamine rānei (aukati H2) (pēnei i a Pepcid®, Tagamet® rānei) i te PPI. Whakaarohia kua pāngia koe e te mamae o te uma i muri i te kai i te kai raukikī. Kātahi, mā te tango i tētahi rongoā pēnei ka whakaora i roto i ētahi meneti, i ētahi haora rānei. Heoi, kāore tōna pānga e roa pērā i te PPI.

He pai ake ngā PPI mēnā he roa, he mau tonu hoki ō raruraru waikawa o te puku.

He pānga taha anō kei te whakamahia i ēnei PPI?

Kāore he raruraru nui o te nuinga o te tangata ina tango PPI. Heoi, pērā i ngā rongoā katoa, ka pā mai ētahi pānga taha. Ko ētahi o ēnei ko:

• Mamae puku
• Te kōroke
• Korere
• Pōuriuri
• Waha maroke
• Ngā mamae o te upoko
• Kirika
• Pupuhi/Hau
• Mārama te upoko
• Te mākūkū me te ponana
• Ruaki

Ahakoa e kiia ana he haumaru ngā PPI, kua kitea e ngā kairangahau he tūponotanga pea ēnei, inā koa ka whakamahia mō te wā roa . Me titiro tātou ki ēnei:

• Mate urutā Clostridioides difficile (C. diff): Ka taea e ngā PPI te whakarerekē i te taurite i waenga i ngā huakita pai me ngā huakita kino i roto i tō puku, ka piki ake te tūponotanga o te whakawhanake i ngā mate urutā pēnei i te C. diff.
• Ngā whati: Ka taea e ngā PPI te whakaiti i te kaha o tō tinana ki te mimiti i te konupūmā, he kohuke e āwhina ana ki te pupuri i te kaha o ō tātou wheua. E whakatūpato ana te U.S. Food and Drug Administration (FDA) ka piki ake pea te mōrearea o ngā whati i te hope, te ringaringa, te tuaiwi rānei i ngā PPI.
• Mate whatukuhu:Ka taea e ēnei te whakanui ake i te mōrearea o te whakawhanake i te mate tākihi mau tonu (CKD), te kino ake rānei o ngā āhuatanga o nāianei.
• Te korenga o ngā kai: Ka taea e ngā PPI te whakaiti i te kaha o tō whekau iti ki te mimiti i te konupora, i te huaora B12 rānei. He kohuke te konupora e āwhina ana i ō tātou uaua me ngā io kia mahi tika. He mea nui te huaora B12 mō tō tātou pūnaha io me ngā pūtau toto whero.

Kei te rangahauhia tonutia te hononga i waenga i ngā PPI me ēnei āhuatanga mōrearea. Heoi anō, ko te tikanga, ka tūtohu ngā tākuta kia whakamahia te horopeta iti rawa, ā, kia poto rawa te wā tae noa ki te pai haere o ō tohu. Mā tēnei ka whakaiti i te mōrearea o ēnei āhuatanga mōrearea.

Āhea ahau me toro atu ki taku tākuta?

Mena kua tohua e te tākuta ngā PPI māu, me pātai atu ki tō tākuta mēnā he pātai āu mō te tango i te rongoā, te wā me mutu, me pēhea rānei te whakaiti i te horopeta.

Mena kei te tango koe i ngā PPI mai i te whare rongoā, ā, ki te whakaaro koe me whakamahi koe i aua PPI i ia rā hei whakahaere i ō tohumate, me toro tonu koe ki te tākuta. Ka taea e ia te tohutohu i a koe mō te horopeta tika me te roa o te wā me tango e koe te rongoā.

Waihoki, ki te pāngia koe e tētahi o ēnei pānga kino kino, me toro atu ki te tākuta tonu:

• te mate pāwera (te kiri mākūkū, te whero, te pupuhi)
• Ngā tohu o te pakaru o te whatukuhu (te iti o te mimi i mua, te pupuhi o ngā ringa me ngā waewae, ngā pona waewae)
• Ngā tohu o te korenga o te konupora (te wiri, te pā o te ngakau, te wiri o te uaua)
• Ngā tohu o te korenga o te huaora B12 (mamae o ngā ringa me ngā waewae, ngoikore, ngenge, pōuriuri, pōhēhē)
• Mena ka whero te kiri, ka pupuhi, ka āhua rānei kei te tihore
• Mena he mate korere nui tōu
• Mena he kirika tōu

Nā, he aha te karere whakamutunga hei kawe ki te kāinga?

Ka tino mamae te nui rawa o te waikawa o te puku, te wāhi hē rānei o te puku. Ka kino hoki tō pūnaha nakunaku. He waimarie, he maha ngā rongoā hei āwhina mēnā kei a koe ēnei tohu.

Mō te whakaora wā poto, he pai ake te whakamahi i te rongoā antacid, i te H2 blocker rānei. Engari ki te pāngia koe e te mamae o te puku, ki te mate puku rānei, ka tohua pea e tō tākuta he momo PPI. Kua roa ēnei rongoā e whakamahia ana, ā, e kiia ana he rongoā haumaru, whai hua hoki. He maha ngā tāngata e kite ana i te whakaora mā te whakamahi i ēnei rongoā.

Ko te mea nui, me whakamahi noa i tēnei rongoā i raro i te tohutohu a te tākuta, i roto i te horopeta kua whakaritea, me te roa hoki o te wā kua whakaritea.Ki te ngana koe ki te whakamahi i te rongoā i te ara e hiahia ana koe, ka ara ake pea ngā raruraru. Nō reira, he mea whakaaro nui kia whakarongo tonu ki ngā kōrero a te tākuta, kia tangohia hoki te rongoā i runga i te tikanga.

` Ngā PPI, te gastritis, te mumura o te puku, te reflux waikawa, ngā mate puku, omeprazole, pantoprazole