Ngā mea e hiahia ana koe kia mōhio mō ngā 'Statins' hei whakahaere i te cholesterol

I kitea i roto i tō whakamātautau toto hou he teitei ake tō taumata cholesterol? I mataku, i āwangawanga rānei koe i tō kitenga kua teitei hoki tō taumata "cholesterol kino" LDL rānei? Mena koinā, kua tohua pea koe e tō tākuta kia tīmata koe ki te tango i tētahi momo rongoā 'Statin'. Nō reira, i tēnei rā, me kōrero māmā noa iho mō ngā 'Statin', he mea nui ki te tini o te tangata.

Āe, he aha ēnei 'Statins'?

He māmā noa iho, ko ngā 'Statins' he momo rongoā e tohua ana e ngā tākuta hei whakaheke i te taumata o te cholesterol i roto i tō toto, inā koa te cholesterol "kino".

Ina kōrero tātou mō te cholesterol, e rua ngā momo e rangona ana e tātou, tika?

1. LDL (Lipoprotein iti-kiato): Koinei te mea e kiia nei e tātou he cholesterol "kino" . Whakaarohia ō uaua toto he paipa e kawe ana i te wai. Ko tā tēnei cholesterol LDL he whakatakoto pērā i te paru hinu ki roto o taua paipa, ka āta whakawhāiti haere i te ara mō te rere o te toto. Ka taea e ētahi momo 'statins' te whakaiti i tēnei cholesterol kino mā te 50% neke atu rānei.

2. HDL (Ripoporoiti Matotoru-Teitei): Koinei te mea e kiia nei e tātou he cholesterol "pai" . Ka kohia e ia te cholesterol kino kua hangai ki roto i ngā oko toto ka tukuna ki te ate kia tangohia mai i te tinana. He rite ki te kaikohi para.

Ehara i te mea ka whakaitihia e ngā statin te cholesterol LDL kino anake, engari ka āwhina hoki ki te whakaiti i ngā triglycerides, tētahi atu momo ngako i roto i te toto, ā, ka whakanui ake i ngā taumata cholesterol HDL pai.

Ko te tikanga, ka tohua kia tangohia ēnei rongoā kotahi i te rā, i te wā kotahi. Ko ētahi statins ka tino pai te mahi ina tangohia i te pō. Nā te mea he nui ake te cholesterol e whakaputaina ana e ō tātou tinana i te pō. Heoi, ko ētahi statins hou ka rite tonu te mahi ina tangohia i tētahi wā o te rā. Mā tō tākuta tēnei e whakamārama ki a koe.

He pēhea te mahi a tēnei rongoā i roto i te tinana?

He kōrero tino whakamere tēnei. Whakaarohia ko tō ate te wheketere matua e hanga ana i te cholesterol. Inaa, 75% o te cholesterol e hiahiatia ana e tō tātou tinana ka hangaia i roto i tō tātou ate. Ko te toenga ka ahu mai i te kai e kainga ana e tātou.

Nō reira, he whākōkī kei te ate e tino hira ana mō tēnei tukanga hanga cholesterol. Ko te ingoa ko te 'HMG-CoA reductase'. Ka mahi te rongoā 'Statin' hei kaitiaki tatau, e aukati ana i te whākōkī 'HMG-CoA reductase' kia kore e tae atu ki te ate. Kātahi ka ngaro i te ate tētahi rauemi mata e hiahiatia ana hei hanga cholesterol. Nō reira, ka tino heke te nui o te cholesterol e hangaia ana e te ate. Kei te mārama koe?

He aha tātou e hiahia ai ki ngā 'Statins'?

Ko te take matua he whakaiti i te mōrearea o te mate ngakau me te whiu.

E ai ki taku kōrero i mua, ina piki te cholesterol kino i roto i te toto, ka whakatakotoria ki runga i ngā pakitara o ngā uaua toto. I roto i te rongoā, ka kiia tēnei ko te 'Atherosclerosis' . Ko te cholesterol e hangai ana i tēnei ara ka kiia ko te 'plaque'. Ka whakaitihia te wāhi i roto i ngā uaua toto, ā, ka ārai i te rere o te toto.

Whakaarohia te mea ka tupu mēnā ka aukatia te uaua toto e tuku toto ana ki te ngākau pēnei? Kāore te ngākau e whiwhi i te hāora me ngā matūkai e hiahiatia ana e ia. Ka arahi tēnei ki te mate ngākau. Ā, ki te pakū tēnei 'pēra' i roto i te uaua toto e tuku toto ana ki te roro, ka puta he toto totoka, ka puta he whiu.

Ka whakaitihia e ngā statin te cholesterol, ka tino whakaitihia te mōrearea o ēnei mate kino.

He aha ngā momo 'statins' e whakamahia whānuitia ana?

He maha ngā momo 'statins'. Mā tō tākuta e tohu te momo e tika ana māu, me te whai whakaaro ki tō āhua hauora, te taumata cholesterol, me ētahi atu āhuatanga.

I ētahi wā ka puta mai he 'statin' i roto i te pire kotahi me tētahi atu rongoā. Hei tauira, he rongoā e kiia nei ko te ezetimibe me te simvastatin.

Ko wai ngā tāngata e taunakitia ana kia tango i ngā 'Statins'?

Ka tohua e te tākuta he statin māu i runga i te mōrearea whānui o te mate ngakau. Ka whakawhirinaki tēnei ki ngā āhuatanga maha, tae atu ki tō tau, ira tangata, hītori whānau, me te mea kei te kaipaipa koe. Ko ngā statin te tikanga e taunakitia ana mō ēnei tāngata e whai ake nei:

• Mō te hunga kāore e taea te whakaiti i ō rātou taumata cholesterol (ina koa ko ngā taumata LDL i runga ake i te 190 mg/dL) ahakoa te kai me te whakakori tinana .
• Mō te hunga mate huka , i waenga i te 40-75 tau te pakeke, me ngā taumata cholesterol LDL neke atu i te 70 mg/dL.
• Mō te hunga kua pāngia kētia e te mate manawa, te whiu, te mate uaua ā-roto rānei (PAD) .
• Mō te hunga 40-75 tau te pakeke me te taumata LDL neke atu i te 70 mg/dL, ā, he nui te mōrearea ki te mate manawa.
• Mena kua pāngia tetahi o te whānau (ngā mātua, ngā tuākana, teina rānei) e te mate manawa i te wā taitamariki , ā, he nui hoki ōna taumata cholesterol.

He pānga taha anō kei tēnei?

He raruraru tēnei mō te tini o te tangata. He pono, pērā i ngā rongoā katoa, ka pāngia pea ngā statin e ngā pānga taha. Engari ko te mea nui, kāore te nuinga o te tangata e pāngia e ngā pānga taha. Ahakoa ngā pānga taha iti ka memeha haere i te haere tonu o te rongoā.

He mea nui: Ki te pāngia koe e ngā pānga taha, kaua e mutu te tango i tō rongoā. Ko te mea pai ko te kōrero ki tō tākuta mō tēnei. Tērā pea ka taea e koe te whakatau i te raruraru mā te whakarerekē i te momo statin e tangohia ana e koe, mā te whakarerekē rānei i te horopeta.

He tangata kei reira kāore e tika ana kia tango i ngā statins?

Āe. Kāore i te tūtohutia ngā Statins mō ngā wāhine hāpu, ngā whaea whāngai pēpi, me te hunga whai mate ate kino. Me kōrero anō hoki koe ki tō tākuta mō ētahi atu rongoā e tangohia ana e koe. Ka taea e ngā wai hua, inā koa te wai karepe me te wai pamekaranete, te taunekeneke me ētahi statins, nō reira pātai atu ki tō tākuta mō tēnā.

Ka aha mēnā ka mutu te tango i te rongoā?

Kia mutu tāu tango i te statin, ka hoki anō ō taumata cholesterol ki tōna taumata o mua. Ko te tikanga ka piki anō tō tupono ki te mate manawa me te whiu. Nō reira, he rongoā mō te wā roa tēnei.

Āhea te wā tika kia kite tonu i te tākuta

Mena ka pāngia koe e tētahi o ngā tohu e whai ake nei i a koe e tango ana i te statin, rapua tonutia he tohutohu hauora.

• Ki te mea kāore e taea te whakamanawanui, ka mamae nui , ka ngoikore rānei ō uaua, ō hononga rānei.
• Mena kei te mamae tō tinana me te kirika .
• NāuMena he kōwhai te āhua o ō kanohi, o tō kiri rānei (he jaundice).
• Ki te huri tō mimi ki te tae pouri, pērā i te wai o ngā rau tī .

I roto i tēnei āhuatanga, he mea pai kia haere ki te Wāhanga Maimoatanga Ohotata (ETU) o te hōhipera.