He uaua rawa te noho tahi me te mate pukupuku. Ahakoa ka taea e ngā maimoatanga pēnei i te chemotherapy te āwhina i te whakangaro i ngā pūtau mate pukupuku, i ētahi wā ka puta he raruraru ohorere i aua maimoatanga. I tēnei rā, ka kōrero tātou mō tētahi āhuatanga ohorere e hiahia ana kia arohia tonutia, ā, ka taea hoki te whakararu i te ora . Ko te Tumor Lysis Syndrome tēnei.
He aha te Tumor Lysis Syndrome? Kia mārama tātou.
Ki te whakarapopototanga, ko te Tumor Lysis Syndrome he rōpū o ngā mate kino e puta ana ina mate te tini o ngā pūtau matepukupuku i te wā kotahi, ā, ka tukuna ngā ihirangi o aua pūtau ki roto i te toto. Whakaarohia, ka puta pea tēnei mate i roto i ētahi haora i muri i te tīmatanga o te maimoatanga matepukupuku. Ka tere te whanake, ā, ka noho hei mate e hiahia ana kia rongoatia wawetia. Nō reira, kei te rapu tonu ngā tākuta i tēnei.
Engari he rongo pai tēnei. He huarahi ā ngā tākuta hei ārai i te mate pukupuku . Mā te tautuhi ko wai kei te mōrearea nui ake, me te mahi i ngā mahi hei whakaiti i taua mōrearea.
He aha ngā mea ka pā ki ō tātou tinana i roto i tēnei āhuatanga?
Ina pāngia ngā pūtau matepukupuku e te ahotea, inā koa mai i ngā maimoatanga pēnei i te chemotherapy, ka pakaru. Kātahi ka kohia ohoreretia ngā matū me ngā paitini i roto i aua pūtau ki roto i te toto. Ka tīmata te raruraru ina kore e taea e tō tātou tinana te tango wawe i ēnei. Ka pā pea tēnei mate pukupuku pakaru ki tō tātou ngākau, ki ō tātou whatukuhu, me ō tātou uaua. Kia titiro tātou he aha ēnei pānga:
- Hyperuricemia - Ko te tikanga tēnei he pikinga ake o te waikawa uric: Ina piki te waikawa uric i roto i te toto, ka taea te whakatakoto ki roto i ngā whatukuhu, ka puta ai te ngoikore o te whatukuhu, tae atu ki te ngoikore o te whatukuhu. Whakaarohia he rite ki te aukati i roto i te paipa wai.
- Hyperphosphatemia - arā, te pikinga o ngā taumata phosphorus: Ka whakararuraru hoki te pikinga o ngā taumata phosphorus i roto i te toto i te mahi a te whatukuhu.
- Hyperkalemia - Ko te tikanga he nui ngā taumata pāhare pāporo: Ina nui ngā taumata pāhare pāporo, ka pāngia pea koe e ngā tohu pēnei i te whakapairuaki, te ruaki, me te korere. Ehara i te mea koinā anake, engari ka rerekē pea te tere o tō manawa, ka puta ai ngā arrhythmias, me te mate manawa pea. He ahua morearea tēnei, kāore?
- Uremia: Ka puta tēnei ina mutu te tātari a ngā whatukuhu i ngā paitini mai i te toto. Ka pā mai he raruraru nui ki ngā wheua, ki ngā uaua, ki te ngākau, me ngā oko toto i roto i te uremia.
- Hypocalcemia - Ngā taumata konupūmā iti: Ka taea e ngā taumata konupūmā iti i roto i te toto te whakaputa i ngā huringa o te manawataki o te ngakau, te mamae o ngā uaua, te pōhēhē, te ngoikore me te ngau o ngā peka. I ētahi wā, ka mate pea i te hopukanga o te ngakau.
Ko te mea tino nui: Ka puta te Tumor Lysis Syndrome ina honoa mai tētahi, neke atu rānei o ēnei āhuatanga.
He āhuatanga ohorere te Tumor Lysis Syndrome?
Āe, tino tika! He āhuatanga ohorere hauora te Tumor Lysis Syndrome e hiahia ana kia rongoatia tonutia. Nō reira, he mea nui kia mōhio koe ki tēnei.
Ko wai ka pāngia e tēnei āhuatanga?
Ehara i te mea ka pāngia te hunga katoa e whiwhi ana i te maimoatanga mate pukupuku e te Tumor Lysis Syndrome. Mena kei te whiwhi koe i te maimoatanga mate pukupuku, he mea pai kia pātai atu koe ki tō tākuta mō tēnei. I te nuinga o te wā, ko te hunga e whiwhi ana i te chemotherapy mō ngā momo mate pukupuku e whai ake nei he nui ake te mōrearea ki te pāngia e tēnei mate:
- Leukemia Lymphocytic Whakapeka
- Ko te Lymphoma Non-Hodgkin kaha, pērā i te Lymphoma Burkitt me te Lymphoma pūtau-B nui horapa
- Te Mate Pūkahukahu Myeloid Koretake (AML)
- Te Mate Pūkahukahu Lymphoblastic Koretake Pūtau-B (ALL)
- Matepukupuku Pūtau Iti
Waihoki, kei reira ētahi atu momo mate pukupuku, ina rongoatia, he iti ake te tūponotanga ki te whakawhanake i tēnei mate. Engari kāore anō kia tino memeha. Hei tauira:
- Lymphoma Pūtau Nui Anaplastic - He mate pukupuku onge tēnei o te pūnaha ārai mate, he puhoi te tipu.
- Te mate toto toto pūmau (CLL)
- Neuroblastoma
- Matepukupuku o te ū
- Te Sarcoma o te Kiko Ngāwari
- Medulloblastoma
- Te Matepukupuku Pūtau Merkel
He aha atu anō ngā take o te Tumor Lysis Syndrome?
E mōhio ana ngā tākuta he nui ake te tūponotanga o ētahi tāngata ki te pāngia e tēnei mate. Me mahi ngā mahi ārai motuhake i mua i te hoatutanga o te chemotherapy ki ēnei tāngata. Anei ētahi āhuatanga e whakanui ake ai i te tūponotanga:
- He tino teitei te maha o ngā pūtau toto mā.
- Kua teitei kē ngā taumata waikawa uric i roto i te toto.
- He raruraru tākihi tō te tinana.
- Te iti o te wai o te tinana (Te matewai).
- Kei te tino kino te wāhanga o te mate pukupuku (te wāhanga o muri mai o te mate pukupuku).
- He nui ngā pukupuku.
Ka taea tēnei āhuatanga te puta me te kore he chemotherapy?
Ae, engari he tino onge te tupu. Mēnā ka puta, ka kiia e ngā tākuta ko te Spontaneous Tumor Lysis Syndrome.
He aha ngā tohu o te Tumor Lysis Syndrome?
Ko te tikanga ka puta mai ēnei tohu i roto i ngā haora 12 ki te 72 i muri i te tīmatanga o te rongoā chemotherapy. Anei ēnei:
- Whakapairuaki me te ruaki.
- Te korere.
- Ngā panonitanga o te nui o te mimi e mimia ana e koe (tērā pea ka piki, ka heke rānei).
- Te ngoikore me te ngenge.
- Te toto i roto i te mimi (Hematuria).
- Ngā mate haurangi, arā, ngā hopuhopu.
- Ngā mamae o te uaua.
- Te ngoikore o te ngākau.
- Te pāorooro o te ngakau kāore i te ōrite.
- Te toto toto iti (hypotension).
- Mamae Hononga.
Mena ka pāngia koe e tētahi, e ētahi rānei o ēnei tohu i a koe e rongoā ana i te mate pukupuku, me whakamōhio tonu koe ki te tākuta.
He aha i puta ai te Tumor Lysis Syndrome?
I te whakarapopototanga, ka puta tēnei āhuatanga ina mate ohorere, ka tere hoki te mate o te tini o ngā pūtau matepukupuku nā te maimoatanga matepukupuku. Ka kohia ohoreretia ngā matū i roto i ngā pūtau e mate ana (pērā i te pāhare pāporo, te whākōkī, me te waikawa uric) ki roto i te toto.
Ko ō tātou whatukuhu te hunga e tātari ana i ēnei mea kāore e hiahiatia. Engari, ina mate te tini o ngā pūtau i te wā kotahi, kāore e taea e ngā whatukuhu te mahi i tēnei mahi. He rite ki te waikeri e purua ana ina tae mai te nui o ngā para i te wā kotahi. Kātahi ka tīmata te kohikohi o ēnei paitini ki roto i te tinana.
Me pēhea te tautuhi a ngā tākuta i tēnei mate?
Ko te arotahi matua a ngā tākuta ko te ārai i te mate pukupuku. Hei whakatutuki i tēnei, ka whakahaerehia e rātou he whakamātautau toto me te mimi i ia wā, i ia wā, hei whakarite kei te mahi tika ō whatukuhu, ā, kei te tangohia ngā paitini i tō tinana.
He aha ngā maimoatanga mō te Tumor Lysis Syndrome?
Ko te mahi tuatahi a ngā tākuta he ārai i tēnei. Mā te tautuhi i te hunga e nui ake ana te mōrearea, me te mahi i ngā mahi ārai motuhake mō rātou. Engari, ki te puta te mate, ka tīmata tonu te maimoatanga.
Ngā mahi hei ārai:
- Te Whakamakuku ā-roto (IV): Ka āwhina tēnei ki te pupuri i ngā taumata makuku pai, te whakatairanga i te mimi, me te āwhina ki te tango wawe i ngā paitini mai i te tinana.
- Te hoatu rongoā hei aukati i te whakatakotoranga o ngā tioata waikawa uric i roto i ngā whatukuhu: Tērā ētahi rongoā hei āwhina i te whakahaere i ngā taumata waikawa uric.
Te maimoatanga mēnā ka puta te āhuatanga:
- Te hoatu rongoā whakaheke toto: Ka āwhina tēnei ki te tango tere atu i ngā paitini i te tinana.
- GLISH: Te hoatu rongoā hei tango i te nui o te pāhare pāporo me te whākōkī.
- Te hoatu rongoā hei whakarewa i ngā tioata waikawa uric kua hangaia i roto i ngā whatukuhu.
- Dialysis: Ki te kore ō whatukuhu e mahi tika, me dialysis pea koe hei tango i ngā paitini mai i ō toto. He rite tēnei ki te mahi hangai a ō whatukuhu.
Ka taea te whakaora i te Tumor Lysis Syndrome?
Āe, tino tika! Tata ki te 90 ōrau o te hunga e pāngia ana e tēnei mate ka ora. Ko te mea nui ko te tautuhi wawe i te mate me te tīmata wawe i te maimoatanga.
He aha ngā mea ka tupu i muri i te rongoā i tēnei mate?
Ka pā kino pea te mate pukupuku ki ō whatukuhu i te mate pukupuku. Nō reira, ki te pāngia koe e tēnei mate, he mea nui kia pātai atu koe ki tō tākuta mēnā me whai maimoatanga anō koe, me tiaki motuhake rānei kia ora rā anō ō whatukuhu.
Kei te whakapai ake ngā maimoatanga mate pukupuku i ia rā, i ia rā, ā, ka taea e tātou te whakangaro tere i ngā pūtau mate pukupuku. Heoi, i ētahi wā, ina mate ēnei pūtau, ka puta he mate kino e kiia nei ko te Tumor Lysis Syndrome nā ngā matū me ngā paitini e tukuna ana e rātou. Ka pā nui tēnei ki te ngākau me ngā whatukuhu.
Hei whakamutunga, ngā mea hei maumahara (Karere hei tango ki te kāinga)
He wero te rongoā mate pukupuku. I tēnei wā, he mea nui kia tūpato ki ngā āhuatanga ohorere pēnei i te Tumor Lysis Syndrome. Mena kei te rongoāhia koe e te mate pukupuku, me pātai atu ki tō tākuta mena kei te tūpono koe ki tēnei mate. Ka whakamāramahia e rātou ngā tūponotanga ki a koe, ā, ka mahi i ngā mea katoa hei ārai, hei rongoā rānei i tēnei mate mena ka puta. Kaua e warewarehia ngā tohumate, ā, me kōrero tonu ki te tākuta mena ka kite koe i tētahi mea rerekē. Ko te tiaki i tō hauora te mea nui rawa atu!
Te mate pukupuku pakaru, te maimoatanga mate pukupuku, te chemotherapy, te mate tākihi, te hyperkalemia, te hyperuricemia, te ohorere hauora
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