Kodi ma platelet anu ali pamwamba? Tiyeni tikambirane za Thrombocytosis!

Kodi mwapezekanso ndi ma platelet ambiri m'magazi mwanu? Kapena kodi pali munthu amene mumamudziwa amene ali ndi vutoli? Ndizachibadwa kumva mantha pang'ono mukamva chinthu chonga ichi. Koma musadandaule, lero tikambirana za vutoli lotchedwa Thrombocytosis m'njira yosavuta yomwe mungamvetse.

Kodi thrombocytosis ndi chiyani? Mwachidule…

Mwachidule, thrombocytosis imachitika pamene muli ndi ma platelet ambiri m'magazi mwanu. Tsopano mwina mukudzifunsa kuti, “Kodi ma platelet ndi chiyani?” Funso lofunika kwambiri limenelo!

Ma platelet ndi mtundu wa selo laling'ono lomwe limapezeka m'magazi athu. Ntchito yawo yayikulu ndikuletsa kutuluka magazi pakatuluka magazi, monga pakakhala bala. Amagwira ntchito ngati damu laling'ono.

Koma chimachitika ndi chiyani ngati chiwerengero cha ma platelet chikukwera kwambiri? Magazi anu amatha kukhala okhuthala komanso omata. Nthawi zina, ma platelet ochulukirapowa angayambitse magazi kuundana mkati mwa mitsempha yamagazi. Izi zitha kuwonjezera chiopsezo cha matenda monga sitiroko kapena matenda a mtima .

Komabe, si milandu yonse ya Thrombocytosis yomwe ndi yoopsa mofanana. Kuopsa kwa vutoli, komanso ngati mukufuna chithandizo kapena ayi, zimadalira chomwe chayambitsa.

Pali mitundu iwiri ikuluikulu ya thrombocytosis:

Inde, madokotala apeza mitundu iwiri ikuluikulu ya vutoli. Tiyeni tikambirane pang'ono za vutoli.

1. Essential Thrombocythemia (ET) kapena Primary Thrombocytosis

Imeneyi ndi matenda osowa magazi. Imachitika pamene mafupa anu - fakitale ya maselo a magazi mkati mwa mafupa anu - amapanga ma platelet ambiri. Taganizirani izi, maselo ambiri a magazi m'thupi lathu amapangidwa mu mafupa awa. Munthu amene ali ndi vuto la thrombocythemia amapangidwa kwambiri chifukwa cha vuto la kupanga maselo a magazi.

Matendawa, otchedwa ET (Essential Thrombocythemia) , amaonedwa kuti ndi matenda ofala kwambiri m'gulu la magazi otchedwa Myeloproliferative Neoplasm (MPN) .

2. Kuthamanga kwa Thrombocytosis kapena Kuthamanga kwa Thrombocytosis kwachiwiri

Uwu ndi mtundu wofala kwambiri wa Thrombocytosis. Apa ndi pamene thupi lanu limapanga ma platelet ambiri chifukwa cha vuto lina, matenda, kuvulala, opaleshoni, kapena kuchotsedwa kwa ndulu. Mwachidule, thupi lanu limayankha ku chinthu china ndikuwonjezera kuchuluka kwa ma platelet ake.Matenda a thrombocytosis nthawi zambiri amakhala akanthawi kochepa, zomwe zikutanthauza kuti vuto lalikulu likatha, kuchuluka kwa ma platelet kumabwerera mwakale.

Ndani amadwala thrombocytosis?

Matendawa nthawi zambiri amapezeka mwa anthu azaka zopitirira 60. Komanso, akuti mtundu wotchedwa Essential Thrombocythemia (ET) umapezeka mwa akazi kawiri kuposa amuna.

Kodi zifukwa za thrombocytosis ndi ziti?

Zifukwa za mitundu iwiri yomwe takambirana kale ndizosiyana.

Zifukwa za Essential Thrombocythemia (ET)

Matenda a Essential Thrombocythemia (ET) ndi matenda omwe amabadwa nawo m'thupi. Si chinthu chomwe mumabadwa nacho. Chimachitika chifukwa cha kusintha kwa majini ena omwe amakhudzidwa ndi kupanga ma platelet. Izi zimapangitsa kuti mafupa anu apange ma platelet ambiri.

Anthu opitilira theka la omwe ali ndi Essential Thrombocythemia (ET) ali ndi kusintha kwa majini a JAK2 . Kusintha kwa majini a CALR kapena MPL nakonso n'kofala.

Asayansi sanathebe kupeza chomwe chimayambitsa kusintha kwa majini kumeneku, koma kafukufuku wa zimenezi akupitirira.

Zifukwa za Thrombocytosis Yogwira Ntchito

Mtundu uwu umachitika chifukwa thupi lanu limapanga ma platelet ambiri chifukwa cha matenda osiyanasiyana. Kapena, nthawi zina, zitha kukhala chifukwa ma platelet akale amasonkhana m'malo mowonongeka pa liwiro labwinobwino.

Nazi zina mwa zinthu zomwe zingayambitse Reactive Thrombocytosis :

• Kuchepa kwa magazi m'thupi , makamaka kuchepa kwa magazi m'thupi chifukwa cha kusowa kwa ayoni .
• Matenda ena a magazi.
• Mitundu ina ya khansa .
• Matenda monga chibayo .
• Matenda otupa - matenda omwe amayambitsa kutupa m'thupi, monga nyamakazi.
• Kuvulala .
• Kulephera kwa impso .
• Mankhwala ena.
• Opaleshoni, makamaka opaleshoni ya m'mimba.
• Kuchotsa ndulu .
• Kuchiza kusowa kwa vitamini B12 .

Mndandandawu uli ndi zifukwa zochepa chabe zomwe zimafala. Pakhoza kukhala zifukwa zina zambiri zomwe zimayambitsa Reactive Thrombocytosis .

Kodi zizindikiro za thrombocytosis ndi ziti?

Kawirikawiri, anthu omwe ali ndi kuchuluka kwa ma platelet m'magazi samakhala ndi zizindikiro zilizonse, makamaka osati kumayambiriro. Ngati muli ndi Reactive Thrombocytosis , mutha kukhala ndi zizindikiro za matenda omwe adayambitsa matendawa.

Komabe, zizindikiro zikayamba, nthawi zambiri zimakhala zokhudzana ndi kutuluka magazi kosazolowereka komanso magazi kuundana m'thupi lanu. Mutha kuwona zizindikiro monga:

• Mutu .
• Kuvulala mosavuta.
• Kumva kufooka, chizungulire, kapena mutu wopepuka.
• Kutuluka magazi m'mphuno, pakamwa, ndi m'kamwa.
• Kutuluka magazi m'mimba kapena m'matumbo.

Anthu ena omwe ali ndi Essential Thrombocythemia (ET) amatha kukhala ndi vuto lotchedwa Erythromelalgia . Izi zimayambitsa kupweteka, kutupa, komanso kufiira m'manja ndi m'mapazi. Angamvenso dzanzi ndi kumva kuwawa m'manja ndi m'mapazi.

Pa milandu yoopsa, thrombocytosis ingayambitse magazi kuundana m'mimba (monga matenda a Budd-Chari ) ndikuwonjezera chiopsezo cha sitiroko kapena matenda a mtima .

Kodi thrombocytosis imapezeka bwanji?

Popeza thrombocytosis nthawi zambiri siimayambitsa zizindikiro, choyamba chomwe mungakhale nacho ndi ngati mayeso a magazi nthawi zonse (monga, Complete Blood Count - CBC ) akuwonetsa kuchuluka kwa ma platelet.

Thrombocytosis imatanthauzidwa ngati kukhala ndi ma platelet opitilira 450,000 pa microliter imodzi ya magazi. Ngati kuchuluka kwa ma platelet anu kuli kokwera, dokotala wanu mwina angakupatseni mayeso ena a magazi pakatha milungu ingapo kuti aone ngati kuchuluka kwa ma platelet kukupitirira. Kuwonjezeka kamodzi kokha kwa kuchuluka kwa ma platelet kenako kubwerera ku moyo wabwinobwino nthawi zambiri si vuto. Komabe, kuchuluka kwa ma platelet nthawi zonse kungasonyeze vuto linalake.

Pankhani ya reactive thrombocytosis , kuzindikira vuto lomwe linayambitsa vutoli (monga kuchepa kwa magazi m'thupi , khansa, matenda) kungathandize madokotala kuzindikira ndi kuthana nalo. Komabe, ngati dokotala sangapeze chifukwa chachiwiri chotere, adzayesanso kuti aone ngati muli ndi Essential Thrombocythemia (ET) .

Mayeso awa angaphatikizepo:

• Kuyeza magazi m'thupi:Izi zimafufuza ngati ma platelet m'magazi anu akuoneka osazolowereka.
• Kuyesa kwa DNA/majini: Izi zimatha kuzindikira kusintha kwa majini monga JAK2 , komwe nthawi zambiri kumagwirizanitsidwa ndi ET (Essential Thrombocythemia) .
• Kufufuza za mafupa: Izi zimayang'ana mafupa anu kuti awone ngati pali maselo osazolowereka.

Kodi thrombocytosis imachiritsidwa bwanji?

Ngati mulibe zizindikiro, mungafunike kungoyang'aniridwa nthawi zonse.

Matenda otchedwa reactive thrombocytosis (secondary thrombocytosis) nthawi zambiri safuna chithandizo. Nthawi zambiri, kuchuluka kwa ma platelet kumabwerera mwakale matenda omwe adayambitsa kuchuluka kwa ma platelet (monga kuvulala, matenda, kapena zomwe zimachitika chifukwa cha opaleshoni) akatha. Komabe, ngati muli ndi zizindikiro, dokotala wanu adzachiza chomwe chimayambitsa vutoli.

Ngati muli ndi Essential Thrombocythemia (ET) ndipo mukukumana ndi zizindikiro, dokotala wanu angakulangizeni mankhwala angapo, monga:

• Kumwa aspirin yocheperako tsiku lililonse: Mutha kumwa aspirin tsiku lililonse kuti mupewe kuundana kwa magazi. Mlingo wocheperako uwu nthawi zambiri sumayambitsa kusokonezeka kwa m'mimba kapena kutuluka magazi. Komabe, musamwe aspirin nthawi zonse popanda kulankhula ndi dokotala wanu.
• Kumwa mankhwala omwe amachepetsa kuchuluka kwa ma platelet: Mankhwala monga Hydroxyurea (mayina a mayina: Droxia®, Hydrea®, Siklos®, Mylocel®) ndi Anagrelide (dzina la mayina: Agrilyn®) amachepetsa kupanga ma platelet mu fupa la mafupa. Interferon alfa (dzina la mayina: Multiferon®) imaletsa ma platelet osadziwika kuti agawikane ndi kuchulukana.
• Kukhala ndi njira yochotsera ma platelet anu: Ngati kuchuluka kwa ma platelet anu kuli kwakukulu kwambiri kotero kuti muli pachiwopsezo chopanga magazi kuundana omwe angawononge moyo wanu, dokotala wanu angakulangizeni njira yotchedwa plateletpheresis . Izi zimaphatikizapo kugwiritsa ntchito makina kuti muchotse ma platelet ochulukirapo m'magazi anu. Komabe, nthawi zambiri matenda a thrombocytosis , plateletpheresis sikofunikira.

Chofunika: Musayambe kapena kusiya chithandizo chilichonse mwa izi popanda upangiri wa dokotala. Chilichonse chiyenera kukambidwa ndi dokotala wanu ndipo chiyenera kuchitika motsogozedwa ndi iye.

Kodi thrombocytosis ingachiritsidwe kwathunthu?

Matenda Ofunika Kwambiri a Thrombocythemia (ET)Pakadali pano palibe mankhwala a thrombocytopenia. Komabe, dokotala wanu angakuthandizeni kuthana ndi vutoli kuti muchepetse chiopsezo cha magazi kuundana. Pankhani ya reactive thrombocytosis (yomwe imayamba chifukwa cha zifukwa zina), kuchuluka kwa ma platelet nthawi zambiri kumabwerera mwakale pamene chifukwacho chathandizidwa.

Kodi thrombocytosis ingapewedwe?

Matenda ambiri omwe amayambitsa thrombocytosis sangathe kupewedwa, kuphatikizapo Essential Thrombocythemia (ET) .

Kodi thrombocytosis ndi chiwopsezo cha moyo?

Kuchuluka kwa ma platelet m'magazi sikuika moyo pachiswe, koma mavuto omwe angachitike - monga magazi kuundana kapena kutuluka magazi kwambiri - akhoza kukhala oopsa.

Zomwe zimayambitsa thrombocytosis nthawi zambiri zimakhala zakanthawi kochepa, ndipo sizimayambitsa magazi kuundana kwambiri. Mu Essential Thrombocythemia (ET) , chiopsezo chimakhala chokwera pang'ono. Komabe, dokotala wanu adzakuyang'anirani mosamala, kukupatsani mankhwala ofunikira, ndikuchita njira zofunikira kuti mupewe magazi kuundana oopsa. Choncho musadandaule.

Kodi chiyembekezo cha munthu amene ali ndi thrombocytosis ndi chotani?

Matenda otchedwa reactive thrombocytosis nthawi zambiri amatha vuto lalikulu likachiritsidwa. Ngakhale kuti kuchuluka kwa ma platelet m'magazi anu kungakwezedwe kwa kanthawi kochepa (ndipo mwina kwa nthawi yayitali ndulu yanu itachotsedwa), matenda ena a thrombocytosis nthawi zambiri samayambitsa magazi kuundana.

Essential Thrombocythemia (ET) , kapena primary thrombocytosis, ingayambitse kutuluka magazi kwambiri kapena mavuto otsekeka magazi. Kumwa mankhwala kuti milingo ya ma platelet anu ikhale yabwinobwino kungathandize kupewa izi. Komabe, patatha zaka zambiri muli ndi matendawa, fibrosis ya mafupa (mabala a mafupa) imatha kuchitika. Anthu ochepa omwe ali ndi Essential Thrombocythemia (ET) amathanso kudwala khansa ya m'magazi .

Ndiyenera kupita liti kwa dokotala wanga?

Tsatirani malangizo a dokotala wanu momveka bwino za kuchuluka kwa nthawi yomwe muyenera kupita kukayezetsa kuchipatala komanso ngati muyenera kuyezetsa magazi kuti muwone kuchuluka kwa ma platelet m'magazi anu.

Kodi ndiyenera kupita ku Dipatimenti Yothandiza Anthu Odwala Pangozi (ETU) liti?

Ngati mukumva zizindikiro za sitiroko kapena matenda a mtima, imbani 1990 nthawi yomweyo kapena pitani kuchipatala chapafupi. Dziwani zizindikiro izi.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Mungathe kufunsa dokotala wanu mafunso monga:

• Kodi ndiyenera kuda nkhawa ndi kuchuluka kwa ma platelet m'magazi anga?
• Kodi ndiyenera kuyesedwanso kuti ndione kuchuluka kwa ma platelet anga kachiwiri?
• Ndi mayeso ati omwe ndiyenera kuchita kuti ndidziwe chomwe chimayambitsa matenda anga a Thrombocytosis?
• Kodi mumalimbikitsa chithandizo chanji?
• Ndi kusintha kotani komwe ndingachite pa moyo wanga kuti ndithane ndi vutoli?

Ngati zotsatira za mayeso anu a magazi zikusonyeza kuti ma platelet anu ndi okwera, musachite mantha. Ma platelet anu akhoza kukhala okwera pazifukwa zosiyanasiyana. Zambiri mwa zifukwazi sizifuna chithandizo. Koma ngati muli ndi milingo yambiri nthawi zonse ndipo muli ndi zizindikiro, dokotala wanu adzayesa kupeza chomwe chikuyambitsa. Kuyang'anira mosamala ndi mankhwala nthawi zambiri kumatha kupewa mavuto aakulu okhudzana ndi thrombocytosis.

Pomaliza, zinthu zoti muzikumbukira (Uthenga Wopita Nawo Kunyumba)

Chabwino, lero takambirana zambiri za Thrombocytosis, sichoncho? Ndikukhulupirira kuti mwamvetsa bwino izi.

Chofunika kwambiri ndichakuti musachite mantha ngati mutapeza kuti kuchuluka kwa ma platelet m'magazi anu kuli pamwamba. Si milandu yonse ya Thrombocytosis yomwe ndi yoopsa.

• Matenda a thrombocytosis omwe amayambitsidwa ndi reactive ndi omwe amapezeka kwambiri, ndipo nthawi zambiri amayamba chifukwa cha vuto lina lakanthawi kochepa. Izi zimathandizanso kuti vutoli lithe msanga ngati lachiritsidwa.
• Essential Thrombocythemia (ET) ndi mtundu wosowa kwambiri womwe ungafunike kuthandizidwa kwa nthawi yayitali.
• Onetsetsani kuti mwapita ku mayeso ndi chithandizo choyenera monga momwe dokotala wanu wanenera.
• Musanyalanyaze zizindikiro zilizonse. Pitani kuchipatala mwachangu, makamaka ngati muli ndi magazi osazolowereka, mabala, mutu waukulu, kupweteka pachifuwa, kapena kupuma movutikira.
• Lankhulani momasuka ndi dokotala wanu. Funsani mafunso kapena nkhawa zilizonse zomwe muli nazo.

Kumbukirani, simuli nokha. Ndi malangizo ndi chithandizo choyenera chachipatala, mutha kuthana ndi vutoli bwino ndikukhala ndi moyo wathanzi.