Kodi munamvapo za acetylcholine , kapena (ACh)? Mwina dokotala wanu anakuuzanipo za izo, kapena munawerengapo za izo kwinakwake. Ndi mankhwala ang'onoang'ono koma ofunikira kwambiri m'thupi lathu. Ali ngati munthu wotumiza makalata amene amanyamula mauthenga mkati mwa thupi lathu. Chifukwa chake, lero tikambirana za acetylcholine m'njira yosavuta yomwe mungamvetse.
Kodi kwenikweni Acetylcholine ndi chiyani?
Mwachidule, acetylcholine ndi neurotransmitter . Taganizirani izi, ubongo wanu umafunika kutumiza mauthenga ang'onoang'ono amagetsi kuti asunthe dzanja lanu, aganizire, akumbukire zinazake, zonsezi. Acetylcholine ndi mthenga wa mankhwala womwe umathandiza kunyamula mauthenga amenewo kudzera m'maselo a mitsempha .
Izi zimatchedwanso " choyambitsa " neurotransmitter . Kodi mukudziwa kuti ndi chiyani? "Zimadzutsa" selo ya mitsempha, kutanthauza kuti, zimailimbikitsa, ndikuipangitsa "kutumiza" mauthenga mwachangu. Zili ngati kugogoda pakhomo la munthu wogona ndikunena kuti, "Taona, tengani kalata iyi."
Dzina lakuti acetylcholine limachokera ku zinthu ziwiri zomwe zimapangitsa kuti likhalepo. Chimodzi ndi gulu la acetyl . Izi zimachokera ku chinthu chotchedwa acetyl coenzyme A, chomwe chimapangidwa kuchokera ku shuga wa shuga. China ndi michere yotchedwa choline . Choline imapezeka mwachilengedwe mu yolks ya dzira, soya, chiwindi, ndiwo zamasamba, ndi nyemba. Choline imapangidwanso m'chiwindi chathu.
Acetylcholine imagwira ntchito zambiri zofunika m'thupi lathu, makamaka kuyenda kwa minofu mwaufulu.Izi zimagwira ntchito yofunika kwambiri pa zochita zathu zodziwa bwino, monga kusuntha miyendo ndi miyendo yathu ndi kuyenda. Zimathandizira maselo amitsempha m'minofu yathu, zomwe zimapangitsa kuti achepetse. Sikuti zokhazo, komanso ndizofunikira kwambiri pa maselo amitsempha muubongo wathu, komanso pazochitika monga kukumbukira, kuganiza, ndi kuphunzira.
Kodi acetylcholine (ACh) imagwira ntchito bwanji?
Acetylcholine imasungidwa kumapeto kwa maselo amitsempha, mpaka uthenga uyenera kutumizidwa. Pamene “chizindikiro” chafika kuti chitumize uthenga, acetylcholine yosungidwa iyi imatulutsidwa. Ikatulutsidwa, imapita mumpata waung'ono pakati pa maselo awiri amitsempha. Mpata uwu umatchedwa synaptic cleft .
Pambuyo podutsa pakati pa synaptic cleft, pali mitundu iwiri ya ma receptor omwe acetylcholine amatha kumangirirako. Mitundu iyi ndi:
- Zolandilira za Nikotini
- Zolandilira za Muscarinic
Pambuyo polumikizana ndi ma receptor awa, uthenga wa mankhwala umapita ku selo lotsatira la mitsempha. Uthenga ukatumizidwa, acetylcholine yomwe imatsala mu synaptic cleft simangowonongeka. Enzyme ina yotchedwa acetylcholinesterase imabwera ndikuswa acetylcholine iyi m'zigawo zake, choline ndi acetate. Kenako zigawo zosweka izi zimayamwanso, kubwezeretsedwanso, ndikugwiritsidwa ntchito kunyamula uthenga wina wa mankhwala. Dongosolo lothandiza kwambiri!
Kodi chimachitika ndi chiyani ndi acetylcholine (ACh)?
Acetylcholine ili ndi maubwino ambiri m'thupi lathu. Tiyeni tiwone zazikuluzikulu.
| Mtundu wa cholandirira | Ntchito zazikulu |
|---|---|
| Zolandilira za Muscarinic |
|
| Ma Nicotinic receptors (Nicotinic receptors) |
|
Mitundu yonse iwiri ya ma receptor imakhudzidwa ndi kukumbukira kwathu. Izi zikutanthauza kuti, ndi ofunikira pa kukumbukira kwa nthawi yayitali, kukumbukira kwa nthawi yochepa, kupanga zokumbukira, kuphatikizana kwawo, ndi kubweza kwawo. Mkati mwa ubongo, acetylcholine imagwira ntchito pazinthu zina. Imalimbikitsa chilimbikitso, chidwi/chidwi, kuphunzira, ndi kugona kwa REM (gawo la tulo lomwe timalota).
Kodi ndi zinthu ziti zomwe zimachitika pamene kuchuluka kwa acetylcholine (ACh) kumachepa?
Kuchepa kwa acetylcholine, kapena kusowa kwake, kungayambitse matenda angapo. Ofunika kwambiri mwa awa ndi awa:
- Matenda a Alzheimer : Anthu omwe ali ndi matenda a Alzheimer alibe acetylcholine yokwanira muubongo wawo. Chifukwa cha zimenezi, kuiwala zinthu ndi chizindikiro chachikulu.
- Lambert-Eaton myasthenic syndrome : Matendawa amayamba chifukwa cha kuchepa kwa kutulutsidwa kwa acetylcholine kuchokera ku maselo amitsempha.
- Myasthenia gravis : Iyi ndi matenda omwe amayambitsa chitetezo chamthupi chomwe chimapangitsa kuti minofu ya mafupa ifooke msanga mutagwiritsa ntchito mobwerezabwereza.
Zofunika:Ngati muli ndi zizindikiro izi, pitani kwa dokotala nthawi yomweyo. Musadziyese nokha.
Kodi mankhwala otani omwe amagwiritsidwa ntchito pochiza acetylcholine (ACh) ndi ati?
Mankhwala oletsa cholinesterase ndi gulu la mankhwala omwe amagwira ntchito poletsa enzyme yomwe imaphwanya acetylcholine ndikuwonjezera ntchito ya acetylcholine receptors. Amagwiritsidwa ntchito pochiza matenda a Alzheimer's ndi myasthenia gravis. Donepezil (Aricept®), Rivastigmine (Exelon®), ndi Galantamine (Razadyne®) ndi ena mwa mankhwala awa.
Ndi zakudya ziti zomwe zili ndi choline, zomwe zimathandiza kupanga acetylcholine (ACh)?
Choline, michere yomwe imasanduka acetylcholine, imapezeka mu zakudya zambiri. Mwachitsanzo:
- Chiwindi cha ng'ombe
- Mazira (makamaka yolks)
- Gawo lapamwamba la nyama ya ng'ombe
- Soya wokazinga, nyemba zam'chitini
- Chifuwa cha nkhuku chokazinga
- Nsomba ya cod `(Cod)`
- Quinoa yophikidwa
- Bowa wa shiitake wophikidwa, broccoli wophikidwa ndi Brussels sprouts
- Mkaka (1%) `(Mkaka (1%)`, yogati ya vanila yopanda mafuta `(yogati ya vanila yopanda mafuta)`
Yesani kuwonjezera zakudya izi muzakudya zanu. Zakudya zopatsa thanzi ndizofunikira kwambiri kuti mukhale ndi moyo wathanzi.
Uthenga Wopita Nawo Kunyumba
Kotero, tsopano mwina mukumvetsa kuti acetylcholine (ACh) ndi neurotransmitter yomwe ndi yofunika kwambiri pa ntchito ya ubongo wathu, kukumbukira, ndi ntchito za thupi monga kufooka kwa minofu. Ngati kuchuluka kwake kumachepa, mavuto okumbukira ndi matenda okhudzana ndi minofu amatha kuchitika. Chofunika kwambiri ndichakuti, ngati muli ndi vuto lililonse la thanzi, lankhulani ndi dokotala za izi. Musapite kukalandira chithandizo chifukwa cha malingaliro. Khalani ndi thanzi labwino!
💬 Comments (0)
Palibe ndemanga zomwe zatumizidwa pano. Onjezani ndemanga yanu pano koyamba.
Onjezani ndemanga yanu