Kodi tikambirane za lymphoma yomwe imakhudza dongosolo lanu la mitsempha (CNS Lymphoma)?

Nthawi zina timakumana ndi mavuto akuthupi mwadzidzidzi, eti? Mutu, kuvutika kulankhula, kapena kumva ngati sitingathe kudziletsa. Nthawi zina sitisamala kwambiri ndi izi, koma zingakhalenso zizindikiro za matenda enaake aakulu. Lero, tikambirana za khansa yosowa koma yoopsa yomwe imakhudza mitsempha yathu yapakati.

Kodi CNS lymphoma ndi chiyani?

Chabwino, tiyeni choyamba tiwone chomwe lymphoma iyi yapakati pa mitsempha, kapena `(CNS Lymphoma)` ndi. `CNS` imayimira `Central Nervous System`. Mwachidule, iyi ndi mtundu woopsa wa khansa womwe umayamba mu dongosolo lathu la mitsempha , kutanthauza, ubongo, chingwe cha msana (mtsempha wa msana), madzi a m'mitsempha (madzi ozungulira dongosolo la mitsempha), ndi maso (chifukwa maso ali pafupi kwambiri ndi ubongo). Uwu ndi mtundu wa lymphoma wotchedwa `(Non-Hodgkin lymphoma)` .

`CNS` lymphoma iyi imayamba m'maselo oyera a m'thupi lathu otchedwa lymphocytes . Ma lymphocytes awa ndi gawo la dongosolo lathu la lymphatic. Kodi mukudziwa, dongosolo la lymphatic ili ndi gawo lofunika kwambiri la chitetezo chathu chamthupi. Limathandiza thupi lathu kulimbana ndi matenda ndi matenda. Chifukwa chake, ngati lymphoma iyi imangopezeka mu dongosolo lathu la mitsempha ndipo siipezeka kwina kulikonse m'thupi, timaitcha `primary CNS lymphoma` . Komabe, ngati lymphoma imapezekanso m'zigawo zina za thupi, kuphatikizapo dongosolo la mitsempha, imatchedwa `secondary CNS lymphoma` .

Ngakhale khansa iyi ingayambire aliyense, imayambanso kugwira ntchito kwa anthu omwe ali ndi chitetezo chamthupi chofooka , monga omwe ali ndi kachilombo ka HIV ndi Edzi , makamaka amuna. Anthu azaka zopitilira 65 nawonso ali pachiwopsezo. Komabe, ndi khansa yosowa kwambiri. Ngakhale m'dziko ngati United States, milandu yatsopano pafupifupi 1,500 yokha imanenedwa chaka chilichonse. Chifukwa chake, mosasamala kanthu za vuto lanu, gulu lanu lachipatala lidzakuthandizani kupeza chithandizo chabwino kwambiri cholimbana ndi CNS lymphoma.

Kodi zizindikiro za CNS lymphoma ndi ziti?

Tsopano tiyeni tiwone zizindikiro za lymphoma iyi ya 'CNS'. Kwenikweni, zizindikiro zimasiyana malinga ndi komwe chotupacho chili . Mwachitsanzo, ngati chotupachi chili m'maselo omwe amaphimba ubongo ndi msana ( 'meninges' ), sichingasonyeze zizindikiro zilizonse. Komabe, ngati pali chotupa pafupi ndi maso, pakhoza kukhala kusintha kwa masomphenya. Kapena, ngati pali chotupa mu gawo la ubongo lomwe limalamulira kuyenda, pakhoza kukhala kumva dzanzi, kusintha kwa bwino monga poyenda.

Zizindikiro zodziwika bwino za CNS lymphoma ndi izi:

• Kusanza ndi kusanza
• Kufooka m'manja, miyendo, kapena nkhope
• Kufooka mbali imodzi ya thupi (hemiparesis)
• Kulephera kumva, kusamva
• Kuvuta kumeza (dysphagia)
• Zizindikiro za kupanikizika kwa ubongo (kupweteka mutu kwambiri, kusokonezeka maganizo, kusokonezeka maganizo)
• Mavuto a masomphenya (kuona molakwika, kuona kawiri, kuyenda pansi )
• Kusintha kwa mkhalidwe wamaganizo (kuvutika kulankhula, kuiwala zinthu, kumva kuchedwa)
• Kukomoka (izi zitha kukulirakulira pang'onopang'ono pakatha masiku angapo kapena milungu ingapo)
• Kulephera kulamulira mkodzo ndi ndowe (kusadziletsa kwa mkodzo ndi ndowe)

Kodi n’chiyani chimayambitsa CNS lymphoma?

Kenako, tiyeni tiwone chomwe chimayambitsa CNS lymphoma. Monga mitundu ina ya lymphoma, CNS lymphoma imayamba pamene maselo omwe ali mu lymph nodes ayamba kuchita zinthu molakwika. Maselo amenewa amachulukana mosalamulirika , kutseka maselo athanzi. Mu CNS lymphoma, maselo omwe amayamba kukula molakwika ndi ma lymphocytes, mtundu wa maselo oyera amagazi otchedwa maselo a B.

Ofufuza sakudziwabe chifukwa chake lymphocyte imakhala khansa, koma apeza zinthu zina zomwe zimawonjezera chiopsezo chotenga CNS lymphoma.

Zinthu Zowopsa za CNS lymphoma

Matenda ena omwe amafooketsa chitetezo chamthupi angapangitse kuti pakhale chiopsezo chotenga CNS lymphoma. Zinthu zomwe zimayambitsa matendawa ndi izi:

• HIV/AIDS (makamaka ngati muli ndi kachilombo ka Epstein-Barr )
• Matenda a Wiskott-Aldrich (WIS)
• Matenda a CVID (Common variable immunodeficiency state)
• Ataxia -telangiectasia
• Kugwiritsa ntchito mankhwala oletsa chitetezo chamthupi pambuyo poika chiwalo china

Kodi CNS lymphoma imapezeka bwanji?

Dokotala wanu angakulangizeni mayeso ndi njira zosiyanasiyana kuti mudziwe ngati muli ndi CNS lymphoma. Kuzindikira kumeneku kumatchedwanso cancer staging . Gawo ili la khansa limathandiza madokotala kumvetsetsa momwe khansa yafalikira komanso mankhwala omwe angakhale othandiza kwambiri.

Muyenera kuchita mayeso awa:

• Kuyezetsa thupi : Dokotala wanu adzayesa thanzi la ubongo wanu, msana wanu, ndi maso anu. Adzayesa mitsempha kuti ayese dongosolo lanu la mitsempha (CNS). Akhozanso kuyesa nyali yodulidwa kuti aone ngati pali chotupa kumbuyo kwa diso.
• Mayeso ojambula zithunzi : Kuti muwone komwe khansa ili mkati mwa thupi, monga `(MRI)`, `(CT scan)` kapenaDokotala wanu angakupatseni PET scan. CNS lymphoma nthawi zambiri imafalikira kupitirira dongosolo la mitsempha. Komabe, imatha kufalikira mofulumira mkati mwa dongosolo limenelo.
• Kuyezetsa magazi : Kuyezetsa magazi kungayang'ane maselo anu ngati ali ndi zizindikiro za khansa. Izi zikuphatikizapo kuwerengera magazi onse , kafukufuku wa mankhwala a magazi, ndi kuyezetsa HIV .
• Kuyezetsa minofu ndi madzi : Chitsanzo cha madzi a msana wanu, mafuta a m'mafupa , kapena chotupacho chingatengedwe kuti muwone ngati pali maselo a khansa.

Kodi mankhwala a CNS lymphoma ndi ati?

Ndipotu, palibe njira imodzi yokha yochizira CNS lymphoma. M'malo mwake, gulu lanu lazaumoyo lidzakulangizani njira yochizira yomwe imagwira ntchito bwino kwa inu kutengera zinthu monga msinkhu wanu, kaya muli ndi kachilombo ka HIV/AIDS, komanso ngati khansa yangopezeka kumene kapena yabweranso mutalandira chithandizo (chobwerezabwereza) . Nthawi zambiri, mankhwala osiyanasiyana amagwiritsidwa ntchito.

Mankhwala a CNS lymphoma ndi awa:

• Chemotherapy : Izi zimaphatikizapo kugwiritsa ntchito mankhwala ophera maselo a khansa. Mankhwala ambiri a chemotherapy methotrexate (HD-MTX) nthawi zambiri amagwiritsidwa ntchito pochiza CNS lymphoma yomwe yangopezeka kumene.
• Chithandizo cha radiation : Izi zimagwiritsa ntchito mphamvu zowala kupha maselo a khansa. Mtundu umodzi wa chithandizo cha radiation chomwe chingathandize kuchepetsa zizindikiro ndi radiation ya ubongo wonse . Imapha maselo a khansa mu ubongo wonse.
• Chithandizo cholunjika : Izi zimagwiritsa ntchito zinthu monga mapuloteni ndi ma antibodies kuti ziukire maselo a khansa. Rituximab ndi ibrutinib ndi mankhwala olunjika omwe dokotala wanu angakulimbikitseni.
• Kusamutsa maselo oyambira : Mukasamutsa maselo oyambira, mumapatsidwa maselo athanzi a magazi kuti alowe m'malo mwa maselo a magazi omwe awonongeka ndi mankhwala a khansa monga chemotherapy ndi radiation therapy.
• Mayeso azachipatala : Dokotala wanu angakulangizeni kuti mutenge nawo mbali mu mayeso azachipatala omwe amayesa njira zatsopano zochizira. Mayeso apano akuphunzira momwe mankhwala atsopano ochizira komanso kuphatikiza kwa mankhwala atsopano a chemotherapy kulili kothandiza pochiza CNS lymphoma.

Ngati muli ndi kachilombo ka HIV kapena muli ndi Edzi, muyenera kupitiriza kulandira chithandizo cha antiretroviral (ART) pamene mukulandira chithandizo cha CNS lymphoma.

Kodi mavuto ndi zotsatirapo zake za chithandizo ndi ziti?

Chithandizo cha CNS lymphoma chingayambitse zotsatirapo zoyipa . Dokotala wanu adzakufotokozerani izi pasadakhale. Mwachitsanzo, kuwala kwa ubongo wonse kumapha maselo a khansa muubongo. Komabe, kungayambitsenso zotsatirapo zoyipa zomwe zingakhudze momwe ubongo wanu umagwirira ntchito. Njira zonse zochiritsira zimakhala ndi zoopsa.

Lankhulani ndi dokotala wanu za ubwino ndi zoopsa za dongosolo lanu la chithandizo. Funsani ngati akulangizani chithandizo chochepetsa ululu, chomwe chingakuthandizeni kuthana ndi zotsatirapo zake komanso momwe khansa imakhudzira moyo wanu.

Kodi ndingayembekezere chiyani ndi vutoli?

CNS lymphoma ndi khansa yomwe ikukula mofulumira , ndipo ili ndi mwayi waukulu wobwereranso mutalandira chithandizo. Komabe, mwayi wanu wochira, kapena kuti matenda anu adzathe , zimadalira zinthu zingapo. Zinthu izi zikuphatikizapo:

• zaka zanu
• Thanzi lanu lonse
• Mkhalidwe wanu wa HIV
• Kumene chotupacho chili
• Zotsatira za mayeso anu a magazi (izi zitha kusonyeza momwe khansa yakhudzira ziwalo zanu zamkati)

Gulu lanu lachipatala lidzagwira ntchito nanu kuti mupeze njira yochizira yomwe imakupatsani mwayi wabwino wopulumuka popanda kuchepetsa moyo wanu.

Kodi kuchuluka kwa CNS lymphoma komwe kumachira ndi kotani?

Ofufuza amanena kuti anthu omwe ali ndi khansa amapulumuka khansa poona kuchuluka kwa anthu omwe ali ndi khansa inayake omwe akadali ndi moyo pakapita nthawi inayake, nthawi zambiri zaka zisanu. Chiwerengero cha anthu omwe ali ndi CNS lymphoma omwe amapulumuka zaka zisanu ndi pafupifupi 30% . Izi zikutanthauza kuti anthu atatu mwa anthu khumi aliwonse omwe ali ndi CNS lymphoma amakhala ndi moyo pakapita zaka zisanu.

Komabe, ziwerengerozi ndi za anthu ambiri . Siziganizira zinthu zina zomwe zimakhudza mwayi wa wodwala wopulumuka. Mwachitsanzo, ngati chitetezo cha mthupi chanu sichinafooke, kapena ngati lymphoma sinafalikire kupitirira ubongo, zotsatira zake nthawi zambiri zimakhala zabwino. Komanso, kuchuluka kwa kupulumuka kumeneku sikukusonyeza momwe mankhwala atsopano akukhudzira moyo wanu.

Dokotala wanu ndiye munthu wabwino kwambiri woti akufotokozereni za tsogolo lanu kutengera momwe mulili ndi thanzi lanu komanso momwe mwadziwira khansa.

Kodi ndimadzisamalira bwanji?

Kukhala ndi lymphoma kungakhale kovuta kwambiri . Mungadandaule ndi mayeso ndi chithandizo chomwe mudzayenera kulandira. Mwina simukudziwa momwe mungagawire malingaliro anu ndi ena.

Ndi nthawi ngati iyi,Muyenera kuyesetsa kupeza chithandizo chonse chomwe mungathe . Izi zikutanthauza kulankhula ndi okondedwa anu, ngakhale zitakhala zovuta. Kapena, zingatanthauze kufunsa dokotala wanu za chisamaliro cha ochepetsa ululu kapena magulu othandizira . Ulendo wa khansa wa aliyense ndi wosiyana. Koma ndikofunikira kulumikizana ndi ena pa sitepe iliyonse ya ulendowu.

Ndiyenera kupita kwa dokotala liti?

Ngakhale CNS lymphoma yanu itachira (ndiko kuti, simudzakhalanso ndi zizindikiro zilizonse za khansa), muyenerabe kukaonana ndi dokotala nthawi zonse kuti muwone ngati khansayo ikubwereranso. Muyenera kuonana ndi dokotala wanu pafupipafupi m'zaka zisanu zoyambirira mutalandira chithandizo. Izi zili choncho chifukwa milandu yambiri ya CNS lymphoma yomwe imabwereranso imachitika m'zaka zisanu zoyambirira.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala?

Nazi mafunso ena omwe mungafunse dokotala wanu:

• Ndi mayeso ati omwe ndiyenera kuchita kuti ndidziwe dongosolo langa la chithandizo?
• Kodi zoopsa ndi ubwino wa njira zosiyanasiyana zochiritsira ndi ziti?
• Kodi ndiyenera kubwera kangati kudzayesedwa kuti ndione momwe khansa ikugwirira ntchito nditalandira chithandizo?
• Kodi ndine woyenerera kutenga nawo mbali mu mayeso azachipatala ? Kodi mumalimbikitsa kutero?
• Kodi mungandilimbikitse chisamaliro chochepetsa ululu ?

Uthenga wofunika kwambiri woti mupite nawo kunyumba

Matenda a CNS lymphoma ndi matenda oopsa omwe amafunika kuyang'aniridwa mosamala komanso dongosolo la chithandizo lopangidwira inu. Ndikofunikira kugwira ntchito limodzi ndi gulu lachipatala lomwe lili ndi luso lochiza matenda a lymphoma kapena khansa zomwe zimakhudza dongosolo la mitsempha yapakati (CNS).

Gulu lanu lachipatala likhoza kufotokoza njira zomwe mungasankhire chithandizo, kukuthandizani kuwunika ubwino wake ndi zoopsa zake kapena zotsatira zake, ndikukulumikizani ndi akatswiri osamalira odwala omwe angakupatseni chitonthozo pamene mukusankha zochita zina.

CNS lymphoma, dongosolo lapakati la mitsempha, khansa, khansa ya muubongo, lymphoma, chitetezo chamthupi, chithandizo