Kodi muli ndi mawanga kapena zotupa zachilendo pakhungu lanu? Kodi iyi ndi Cutaneous B-Cell Lymphoma?

Khungu lathu ndi chinthu chabwino kwambiri, sichoncho? Nthawi zina ziphuphu zazing'ono zimabwera ndikuchoka. Koma nthawi zina mungakhale mukukayikira pang'ono za malo atsopano kapena chotupa pakhungu lanu, kapena chomwe chakhalapo kwa nthawi yayitali chomwe sichinachiritsidwe. Nthawi ngati zimenezi, tiyenera kusamala pang'ono. Chifukwa, ngakhale kuti ndi chosowa kwambiri, kusintha kwa khungu koteroko kungakhalenso chizindikiro cha matenda aakulu. Lero tikambirana za matenda a pakhungu osowa kwambiri, koma ofunikira kwambiri omwe muyenera kuwadziwa. Umenewo ndi matenda otchedwa cutaneous B-cell lymphoma, kapena `(Cutaneous B-Cell Lymphoma)`.

Kodi Cutaneous B-Cell Lymphoma ndi chiyani?

Mwachidule, Cutaneous B-Cell Lymphoma (CBCL) ndi mtundu wa khansa yomwe imayamba pakhungu lanu. Ndi yosowa kwambiri. Ili m'gulu la khansa yotchedwa lymphoma. Koma chinthu chapadera ndichakuti imayambira kunja kwa ma lymph nodes athu, pakhungu. Ndicho chifukwa chake imatchedwa extranodal lymphoma.

Kawirikawiri, `(CBCL)` iyi imawoneka ngati banga, ziphuphu, kapena chotupa pakhungu. Izi zimakula pang'onopang'ono kwambiri. Zingatenge miyezi, ngakhale zaka, kuti zikule. Komanso, sizifalikira kawirikawiri ku ziwalo zina za thupi. Anthu ena amatchanso `(B-cell skin lymphoma)`. Chifukwa chake, ngati muwona china chake chatsopano kapena chosiyana pakhungu lanu, ndi bwino kuchiyang'anira.

Kodi lymphoma iyi imayamba bwanji? Kodi maselo a B ndi chiyani?

Tsopano mwina mukudabwa chifukwa chake chinthu chonga ichi chimachitika. Kunena zoona, asayansi sanapezebe chomwe chimayambitsa izi (CBCL)`. Koma chinthu chimodzi n'chodziwikiratu: sichili chobadwa nacho kapena chopatsirana.

Zimayamba ndi maselo oyera a m'magazi otchedwa ma lymphocyte. Ma lymphocyte awa ndi ziwalo zofunika kwambiri pa chitetezo chathu chamthupi. Ali ngati gulu lankhondo lomwe limateteza dziko lathu. Pali mitundu iwiri ikuluikulu ya ma lymphocyte: T-cells ndi B-cells. Maselo a B-cell akayamba kukula kwambiri popanda kulamulira, vutoli lotchedwa B-cell lymphoma limachitika. Mwachidule, maselo athu amasokonezeka pang'ono ndipo amakhala maselo a khansa.

Kodi mitundu ikuluikulu ya lymphoma ya khungu ya B-cell ndi iti?

Pali mitundu ikuluikulu inayi ya ``(CBCL)`` iyi. Izi zimagawidwa m'magulu kutengera momwe maselo amaonekera pogwiritsa ntchito maikulosikopu. Mtundu uliwonse ungawoneke mosiyana pakhungu ndipo ungafunike chithandizo chosiyana.

1. Matenda oyamba a khungu otchedwa follicle center lymphoma:

• Uwu ndi mtundu wa `(CBCL)` womwe umawoneka kwambiri.
• Kawirikawiri, zimapezeka pamutu, pakhosi, kapena pachifuwa/mthupi.
• Zimawoneka ngati zotupa zofiira-bulauni, zotupa kapena ziphuphu pakhungu .
• Izi ndi zovuta kwambiri, zikupita patsogolo pakatha miyezi ingapo, mwina zaka zambiri.

2. Mtundu woyamba wa khungu la B-cell lymphoma:

• Uwu ndi mtundu womwe umakula bwino.
• Kawirikawiri zimawoneka ngati zilonda zofiira ngati pinki, timibulu, kapena zotupa .
• Kawirikawiri zimapezeka pa torso kapena m'manja.

3. Mtundu woyamba wa lymphoma wa maselo akuluakulu a B, womwe umapezeka m'thupi:

• Iyi ndi yaying'ono pang'ono poyerekeza ndi mitundu ina iwiri, koma ndi yamphamvu kwambiri. Izi zikutanthauza kuti imakula mofulumira, m'masabata kapena miyezi ingapo.
• Kawirikawiri imawoneka ngati chotupa chimodzi kapena zingapo kapena timibulu pa miyendo, mikono, kapena pachifuwa/chifuwa.

4. Matenda oyamba a khungu otchedwa large B-cell lymphoma, ena:

• Iyi ndi mtundu wosowa kwambiri komanso wankhanza.
• Mawonekedwe ake amatha kusiyana, koma nthawi zambiri amayamba pamutu, pathupi, ndi m'miyendo.

Ndani amene ali ndi mwayi waukulu wopeza matendawa? Kodi ndi ofala bwanji?

Kwenikweni, vutoli lotchedwa ``(CBCL)`` limatha kuchitika mwa aliyense. Palibe kusiyana pakati pa amuna ndi akazi, palibe kusiyana kwa zaka, ndipo lapezeka kuti limapezeka m'mitundu yosiyanasiyana. Chifukwa chake, n'zovuta kuganiza kuti, "Izi sizingandichitikire."

Koma, musachite mantha. Ili ndi vuto losowa kwambiri. Taganizirani izi, ngati mutenga anthu pafupifupi miliyoni imodzi, anayi okha ndi omwe angadwale vutoli. Chifukwa chake, simuyenera kuchita mantha ndikuganiza kuti izi ndi ``(CBCL)``` mukangoona chinthu chachilendo pakhungu lanu. Komabe, ngati muli ndi kukayikira kulikonse, ndi bwino kufunafuna upangiri wa dokotala.

Kodi zizindikiro zake ndi ziti? Onani ngati muli ndi zizindikirozi?

Chizindikiro chachikulu cha `(CBCL)` ndi kusintha kwa khungu. Izi zitha kuwoneka m'njira zosiyanasiyana:

• Ziphuphu
• Chotupa kapena chotupa pakhungu
• Chotupa chaching'ono (chotupa kapena chotupa)

Izi zitha kukhala zofiira, zofiirira, kapena zofiirira. Zina zimakwezedwa komanso zolimba, koma zosalala. Izi zimatchedwa ma papules. Zina zimakhala zathyathyathya, ngati mabala a khungu lokhuthala. Izi zimatchedwa ma plaque. Ziphuphu zazikulu zimatchedwanso ma nodules kapena zotupa.

Pakhoza kukhala malo amodzi okha/chotupa chotere, kapena pakhoza kukhala angapo. Komanso, angawonekere pamalo amodzi okha pathupi kapena m'malo angapo. Akhoza kukhala pafupi, kapena kutali.

Tangoganizirani, Amalume Sunil anali ndi kadontho kofiira m'dzanja lawo kwa miyezi ingapo. Ankaganiza kuti ndi kachikwapu chabe. Koma pang'onopang'ono kanakula n'kukhala ngati chotupa. Ndicho chimene chingakhale chizindikiro choyamba cha izi.

Kawirikawiri, anthu ena amathanso kukumana ndi zizindikiro zina. Izi zimatchedwanso "zizindikiro za B". Izi zikuphatikizapo:

• Malungo omwe amabwera popanda chifukwa.
• Kutuluka thukuta kwambiri usiku.
• Kutupa kwa ma lymph nodes m'khosi, m'khwapa, kapena m'mimba.
• Kuchepetsa thupi popanda chifukwa.

Kupezeka kwa "mawonekedwe a B" awa kumatanthauza kuti matendawa akhoza kufalikira kwambiri. Komabe, izi sizichitika kawirikawiri mu `(CBCL)`.

Kodi madokotala amazindikira bwanji izi?

Anthu ambiri amachedwa kufunafuna upangiri wa dokotala chifukwa mabala ndi ziphuphu zomwe zimawonekera pakhungu la CBCL zimatha kuwoneka ngati ziphuphu wamba, kulumidwa ndi tizilombo, ziwengo, mikwingwirima, kapena matenda ena a pakhungu monga eczema kapena psoriasis. Komabe, ngati muli ndi chinthu chachilendo pakhungu lanu chomwe sichikuchira, muyenera kuwonana ndi dokotala, makamaka dokotala wa khungu.

Dokotala adzayamba kaye wafufuza bwino khungu lanu. Adzayang'ana mbali zonse za thupi lanu ndikuwona ngati pali vuto lililonse.

Kenako, kuti adziwe bwinobwino matendawa, pamafunika "kufufuza khungu" ("skin biopsy"), zomwe zikutanthauza kutenga khungu laling'ono kuchokera pamalo osazolowereka ndikulifufuza. Khungu laling'ono ili limafufuzidwa ndi katswiri (''pathologist'') kuti aone ngati pali maselo a khansa, ndipo ngati alipo, ndi a mtundu wanji. ""biopsy"" ndiyo njira yokhayo yodziwira ngati ndi "skin lymphoma" komanso mtundu wanji wa matendawa.

Kuti aone ngati khansa yafalikira, dokotala wanu angakupatseni mayeso ena (`mayeso oyesera`). Izi zingaphatikizepo:

• Kuyezetsa magazi.
• Mayeso ojambulira zithunzi monga CT scan kapena PET scan.
• Kufufuza za m'mafupa.
• Kufufuza kwa lymph node.

Tiyeni tiphunzire za magawo ndi kufalikira kwa matendawa.

Gawo la matendawa (CBCL) ndi muyeso wa ngati khansa yafalikira komanso momwe yafalikira. Gawoli ndi lofunika kwambiri chifukwa limasankha chithandizo. Dokotala wanu adzakufotokozerani gawo lomwe matendawa ali komanso momwe angakukhudzireni.

• Gawo 1E: "E" imayimira "extranodal," kutanthauza kunja kwa ma lymph nodes. Pa gawoli, khansa imakhazikika pakhungu ndipo sinafalikire kwina kulikonse. Ngati palibe zizindikiro zina za "B", monga kutentha thupi kapena kuchepa thupi, izi zimatchedwanso "Gawo 1AE."

Ngati ``CBCL'' yafalikira, madokotala amagwiritsa ntchito njira yotchedwa ``TNM staging system''.

• Chotupa (T): Chilembo "T" chimatanthauza chiwerengero cha ma papules, tinthu tating'onoting'ono, kapena zotupa pakhungu, kukula kwake, ndi komwe zili. Izi zimawerengedwa kuyambira 1 mpaka 3 (kuyambira zochepa mpaka zowopsa kwambiri).
• Ma Node (N):Chilembo "N" chimasonyeza ngati ma lymph nodes akhudzidwa, angati, ndi komwe ali. Izi zimawerengedwanso kuyambira 0 mpaka 3.
• Metastasis (M): Chilembo "M" chimasonyeza ngati lymphoma yafalikira kupitirira khungu kapena ma lymph nodes (`M1`) kapena ayi (`M0`). `(Metastasis)` chimatanthauza kuti khansa yafalikira ku ziwalo zakutali.

Kodi mankhwala ake ndi otani? Kodi angachiritsidwe?

Chithandizo cha `(CBCL)` chimadalira mtundu ndi gawo la matendawa. Nthawi zambiri amatha kuchiritsidwa, makamaka m'njira zapamwamba kwambiri. Komabe, nthawi zina matendawa amatha 'kubwereranso'.

Pali njira zingapo zochizira:

• Kuyang'anira odwala mwachangu: Nthawi zina matendawa akamakula ndipo sakuyambitsa mavuto aakulu, madokotala amatha kugwiritsa ntchito njira ya "kuyang'anira ndi kudikira". Izi zikutanthauza kuti, amawunika matendawa mpaka atayamba kulandira chithandizo.
• Chemotherapy: Kupereka mankhwala opha maselo a khansa. Mankhwalawa angatengedwe ngati mapiritsi kapena jakisoni.
• Mankhwala obayidwa pakhungu kapena obayidwa: Mankhwala monga corticosteroids angagwiritsidwe ntchito pakhungu kapena kubayidwa mwachindunji mu chotupacho.
• Ma antibodies a monoclonal: Mankhwala monga `(Rituximab)` ali m'gululi. Awa amagwira ntchito ngati mankhwala ochizira ndipo amawononga maselo a B.
• Chithandizo cha radiation: Kugwiritsa ntchito kuwala kwamphamvu kwambiri kuwononga maselo a khansa. Izi nthawi zambiri zimakhala zothandiza pa zotupa zapafupi.
• Kuchotsa chotupa pa opaleshoni: Nthawi zina, ngati pali chotupa chimodzi, chingachotsedwe kwathunthu ndi opaleshoni.

Dokotala wanu adzakambirana nanu njira yochiritsira yomwe ili yoyenera kwa inu.

Kodi pali njira yopewera izi kuti zisachitike?

Tsoka ilo, popeza chomwe chimayambitsa `(CBCL)` sichikudziwikabe, palibe njira zotsimikizika zopewera izi. Chifukwa chake, chinthu chabwino kwambiri chomwe tingachite ndikuzindikira kusintha kulikonse kwachilendo pakhungu lathu ndikupempha upangiri wachipatala nthawi yomweyo ngati tiwona chilichonse.

Kodi chiyembekezo cha kuchira ndi chiyani? (Zomwe zidzachitike)

Kuyembekeza kwa matendawa, kapena momwe matendawa akuonekera, kumadalira zinthu zingapo, makamaka mtundu wa lymphoma ndi siteji ya matendawa.

• Mitundu iwiri yodziwika bwino (`Primary cutaneous follicle center lymphoma` ndi `Primary cutaneous marginal zone B-cell lymphoma`): Iyi ili ndi chiŵerengero cha moyo cha zaka zisanu cha pafupifupi 95%. Izi zikutanthauza kuti patatha zaka zisanu kuchokera pamene matendawa adapezeka, odwala 95 mwa 100 aliwonse akadali ndi moyo. Ichi ndi chikhalidwe chabwino kwambiri.
• Mitundu yoopsa kwambiri (`Primary cutaneous diffuse large B-cell lymphoma, leg type` ndi `other`): Iyi ili ndi chiŵerengero cha moyo cha zaka zisanu cha pafupifupi 60%.

Ziwerengerozi ndi za avareji chabe. Mkhalidwe wanu ukhoza kukhala wabwino kapena woipa, choncho ndi bwino kulankhula ndi dokotala wanu za izi.

Kodi ndingabwererenso nditalandira chithandizo?

Inde, lymphoma ya khungu imatha kubwereranso pambuyo pa chithandizo. Ziphuphu zimatha kubwereranso pamalo omwewo kapena pamalo atsopano. Nthawi zambiri, mtundu womwewo umabwereranso. Komabe, nthawi zambiri, CBCL yobwereranso ikhoza kukhala matenda a systemic kapena mtundu wina wa lymphoma.

Chifukwa chake, ndikofunikira kwambiri kuyang'ana khungu lanu nthawi zonse ('kufufuza khungu') ndikupita kukayezetsa khungu lanu nthawi zonse ndi dokotala wa khungu kapena katswiri wina.

Kodi mumasamalira bwanji thanzi lanu monga munthu amene ali ndi CBCL?

Ngati muli ndi (CBCL) kapena munali nayo kale ndipo munachira, ndikofunikira kwambiri kutsatira malangizo a dokotala wanu. Muyenera kupitiriza kuyesedwa kuti muwonetsetse kuti matendawa sanabwererenso.

Kangati mayesowa amachitidwa zimasiyana malinga ndi mtundu wa CBCL komanso momwe imakhalira yoopsa. Zitha kuchitika milungu ingapo iliyonse, miyezi ingapo iliyonse, kapena kamodzi pachaka. Maulendo otsatirawa angaphatikizepo kuyezetsa khungu, kuyezetsa magazi, ma x-ray, kapena biopsy.

Mafunso omwe muyenera kufunsa dokotala wanu

Ngati mwapezeka ndi `(Cutaneous B-Cell Lymphoma)`, musaiwale kufunsa dokotala wanu mafunso awa:

• Kodi ndi mtundu wanji wa `(CBCL)` womwe ndili nawo?
• Kodi izi zili pa siteji iti?
• Kodi mumalimbikitsa chithandizo chamtundu wanji?
• Kodi zotsatirapo zake ndi zoopsa zake ndi ziti?
• Kodi chiyembekezo changa cha matenda ndi chiyani?
• Kodi zimatenga nthawi yayitali bwanji kuti mudziwe ngati chithandizocho chayenda bwino kapena ayi?
• Kodi ndiyenera kukuonani kangati kuti nditsimikizire kuti lymphoma sinabwererenso?

Mayankho a mafunso awa adzakuthandizani kumvetsetsa bwino matendawa ndi njira zotsatirazi.

Uthenga Wopita Nawo Kunyumba Kuchokera ku Zimene Takhala Tikukambirana

Lymphoma ya khungu la B-Cell ndi mtundu wosowa wa khansa womwe umayamba m'maselo otchedwa lymphocytes pakhungu.

• Matenda ambiri amakula pang'onopang'ono ndipo safalikira ku ziwalo zina za thupi. Komabe, mitundu ina imatha kukhala yaukali ndikufalikira.
• Ngati muwona chotupa chatsopano, chosachira, banga, kapena ziphuphu pakhungu lanu, musachinyalanyaze . Pitani kwa dokotala, makamaka dokotala wa khungu, nthawi yomweyo.
• Mitundu yambiri ya CBCL imatha kuchiritsidwa mwa kuzizindikira msanga komanso kulandira chithandizo choyenera.
• Chifukwa matendawa amatha kubwereranso pambuyo pa chithandizo,Ndikofunikira kwambiri kuyezetsa magazi nthawi yomwe dokotala wakupatsani.

Kumbukirani, izi ndi zongopereka chidziwitso chokha. Ngati muli ndi nkhawa zilizonse zokhudza thanzi lanu, ndi bwino kufunsa upangiri kwa dokotala.

` Lymphoma ya B-Cell ya Cutaneous, Khansa ya Pakhungu, Lymphoma, B-Cell, Ziphuphu za Pakhungu, Matenda a Pakhungu