Kodi muli ndi chotupa pathupi lanu? Kodi ichi ndi Epithelioid Sarcoma? Tiyeni tidziwe bwino!

Ndizachilendo kumva nkhawa pang'ono mukaona chotupa chaching'ono kapena chotupa kwinakwake pathupi lanu, eti? Nthawi zina ngati zimenezo, mumaganiza zinthu zambiri. "Ichi ndi chiyani? Kodi n'choopsa?" Mafunso ngati awa amabwera m'maganizo mwanga. Lero tikambirana za mtundu wosowa kwambiri wa khansa womwe ungawoneke ngati chotupa chotere. Chomwecho chimatchedwa Epithelioid Sarcoma . Ngakhale dzinalo lingamveke lachilendo pang'ono, ndikofunikira kudziwa za icho.

Kodi Epithelioid Sarcoma ndi chiyani? Kunena zoona…

Mwachidule, Epithelioid Sarcoma (ES) ndi mtundu wosowa kwambiri wa khansa womwe uli m'gulu la khansa lotchedwa soft tissue sarcomas . "Minofu yofewa" imatanthauza zinthu zomwe zili m'thupi lathu monga minofu, minofu yamafuta, mitsempha yamagazi, ndi mitsempha. Chifukwa chake khansa iyi imakula m'malo otere.

Nthawi zambiri imayamba ngati chotupa pa manja anu, m'manja, m'zala, m'miyendo ya m'munsi, kapena m'mapazi anu . Komabe, imatha kufalikira kulikonse m'thupi lanu. Nthawi zina, chotupa choposa chimodzi chingatuluke. Anthu ena amakhalanso ndi zilonda pakhungu pomwe pali chotupacho.

Chabwino kwambiri ndichakuti, epithelioid sarcoma ndi khansa yomwe ikukula pang'onopang'ono . Tangoganizani, anthu ena akhoza kukhala ndi khansa yamtunduwu kwa miyezi ingapo, ngakhale zaka zambiri, osawonetsa zizindikiro zilizonse. Izi zikutanthauza kuti imatha kukula m'thupi lanu popanda inu kudziwa.

Izi zimatchedwanso epithelial sarcoma. Pali mitundu iwiri ikuluikulu ya izi: distal ndi proximal. Tiyeni tiwonenso zimenezo.

Kodi pali mitundu ina ya izi? Kodi ndi chiyani?

Inde, monga tanenera kale, pali mitundu iwiri ikuluikulu ya epithelioid sarcoma.

• Mtundu wakutali: Uwu ndiye mtundu wofala kwambiri . “Distal” amatanthauza kutali ndi pakati pa thupi. Izi zikutanthauza kuti mtundu uwu umapezeka kwambiri m'malo monga manja anu, mapazi, kutsogolo kwa manja anu, ndi pansi pa miyendo yanu .

• Mtundu wa Proximal: Uwu ndi mtundu wosowa kwambiri . "Proximal" amatanthauza pafupi ndi pakati pa thupi. Chifukwa chake, Proximal Epithelioid Sarcoma (PES) iyi imatha kufalikira m'malo monga pachifuwa, m'mimba, m'khwapa, m'mimba (monga mbolo kapena vulva), kapena mutu ndi khosi .

Kawirikawiri, mtundu uwu wa proximal umakhala waukulu pang'ono kuposa mtundu wa distal.Waukali. Izi zikutanthauza kuti ukhoza kufalikira mofulumira pang'ono ndikuipiraipira. Chifukwa cha zimenezi, zingakhale zovuta pang'ono kuchiza.

Kodi epithelioid sarcoma ndi yofala bwanji? Ndani amene ali ndi mwayi waukulu woidwala?

Iyi ndi khansa yosowa kwambiri. Tangoganizirani, pali mitundu yoposa 50 ya sarcoma ya minofu yofewa. Zonse pamodzi, zimakhala pafupifupi 1% ya khansa zonse mwa akuluakulu. Ndipo, epithelioid sarcoma iyi, kachiwiri, ndi chiwerengero chochepa kwambiri, pafupifupi 1% ya sarcoma ya minofu yofewa. Izi zikutanthauza kuti, ndi yosowa kwambiri.

Malinga ndi akatswiri, ngakhale m'dziko ngati America, pakadali pano pali anthu osakwana 1,000 omwe ali ndi epithelioid sarcoma iyi. Kotero mutha kuganiza momwe izi zilili zachilendo.

Kawirikawiri,

• Mtundu wa Distal ES - mtundu wofala kwambiri - umakhudza kwambiri achinyamata ndi achinyamata .
• Mtundu wa proximal ES - mtundu wosowa, woopsa pang'ono - umapezeka kwambiri mwa okalamba .

Kodi zizindikiro zake ndi ziti? Kodi mumazindikira bwanji?

Poyamba, epithelioid sarcoma siingayambitse zizindikiro zilizonse. Izi zikutanthauza kuti simungazindikire chilichonse cholakwika ndi khansa. Komabe, pamene chotupacho chikukulirakulira, mungazindikire zizindikiro monga:

• Chotupa chatsopano kapena kutupa kumawonekera. Ichi chingakhale chaching'ono kapena chachikulu.
• Zilonda zimapangika pamwamba pa khungu pomwe pali chotupa, mofanana ndi kudula pang'ono kapena bala.
• Ululu umamveka. Koma izi zimachitika pokhapokha ngati chotupacho chili chachikulu pang'ono ndipo chikukankhira minofu kapena mitsempha yozungulira. Si aliyense amene amamva ululu.
• Zikumveka ngati chotupa chomwe chakhalapo kwa nthawi yayitali chikukulirakulira .

Chofunika: Ngati muwona chotupa chatsopano kapena kutupa kotereku kulikonse mthupi lanu, kapena ngati mukumva kuti chomwe chilipo chikukulirakulira, onani dokotala . Zingakhale zosavuta, koma ndibwino kukayezetsa.

N’chifukwa chiyani izi zimachitika? Kodi zifukwa zake ndi ziti?

Kunena zoona, madokotala sanganenebe chomwe chimayambitsa epithelioid sarcoma. Komabe, kafukufuku wapeza kuti imagwirizanitsidwa ndi vuto la jini lotchedwa SMARCB1 . Jini iyi ndi yomwe imauza thupi lathu kupanga mapuloteni. Kusintha kwa majini kumeneku kumachitika nthawi zambiri pa moyo. Izi zikutanthauza kuti si chinthu chomwe mumabadwa nacho, nthawi zambiri.

Monga ma sarcoma ambiri ofewa a minofu, ma epithelioid sarcoma nthawi zambiri amakula popanda chifukwa chomveka bwino . Komabe, nthawi zambiri amapezeka pambuyo pa khansa yapitayi.Chiwopsezo chotenga izi ndi chachikulu pang'ono kwa anthu omwe adachitidwapo chithandizo cha radiation.

Kuphatikiza apo, akatswiri apeza kuti anthu omwe ali ndi matenda enaake a khansa m'banja angakhalenso pachiwopsezo chowonjezeka cha matenda a epithelioid sarcoma. Zina mwa matenda awa ndi monga:

• Matenda a Gardner
• Mtundu wa Neurofibromatosis Mtundu 1 ndi Mtundu 2
• Retinoblastoma
• Matenda a Li-Fraumeni
• Matenda a chifuwa chachikulu (tuberous sclerosis complex)
• Matenda a Werner
• Matenda a Gorlin

Izi n'zovuta pang'ono, koma ndi bwino kudziwa. Ngati muli ndi vutoli, lankhulani ndi dokotala wanu kuti akupatseni malangizo ena.

Kodi matendawa amafalikira m'thupi lonse?

Nthawi zambiri, epithelioid sarcoma sifalikira (kufalikira) kumalo ena. Izi zikutanthauza kuti, imakhalabe komwe idayambira. Komabe, nthawi zina, makamaka mitundu yoopsa kwambiri monga proximal type, imatha kufalikira. Ngati itatero, nthawi zambiri imapita ku ma lymph nodes, mapapo, ndi mafupa anu.

Kodi mumazindikira bwanji izi? (Kuzindikira)

Dokotala adzayesa mayeso angapo kuti adziwe matenda a epithelioid sarcoma. Mayeso akuluakulu ndi awa:

• Kuwunika thupi : Dokotala adzakuyang'anirani, akufufuza zinthu monga malo a chotupa ndi kukula kwake.
• Kufufuza za khansa: Iyi ndi njira yofunika kwambiri yoyezera khansa . Kachidutswa kakang'ono kwambiri ka chotupacho kamatengedwa ndikuyang'aniridwa ndi maikulosikopu. Pokhapokha tingadziwe ngati ndi khansa, ndipo ngati ndi khansa, mtundu wake.
• Kuyezetsa magazi kwa khansa: Zizindikiro zina za khansa zimapezeka m'magazi.
• Kujambula kwa MRI (Magnetic Resonance Imaging - MRI): Izi zimatha kuona bwino komwe chotupacho chili, kukula kwake, komanso ngati chafalikira ku minofu yozungulira.
• Kujambula kwa CT (Computed Tomography - CT scans): Izi zitha kuwonanso chotupa ndikuwona ngati khansa yafalikira kumadera ena, monga mapapo.
• Kujambula kwa PET (Positron Emission Tomography - Kujambula kwa PET): Izi zimathandiza kupeza malo m'thupi momwe maselo a khansa amagwira ntchito.

Mwina simungafunike kuchita mayeso onsewa. Dokotala wanu adzasankha mayeso ofunikira kutengera momwe mulili.

Kodi chithandizo chake ndi chiyani?

Dokotala wanu adzasankha njira yochizira matenda potengera zinthu zingapo, kuphatikizapo kukula kwa chotupacho, komwe chili, ngati khansayo yafalikira kumadera ena, mphamvu ya thupi lanu yochira, komanso zomwe mumakonda.

Opaleshoni

Chithandizo chachikulu komanso chofala kwambiri cha epithelioid sarcoma ndi kuchotsa chotupacho ndi opaleshoni . Ngati khansa yafalikira ku ma lymph nodes apafupi, dokotalayo angawachotsenso.

Chithandizo cha X-ray

Iyi ndi njira ina yodziwika bwino yochizira khansa. Imagwiritsa ntchito ma X-ray amphamvu kwambiri kuti iwononge maselo a khansa. Madokotala angapereke chithandizochi kuti achepetse chotupa musanachite opaleshoni. Kapena, ingagwiritsidwe ntchito kupha maselo ena onse a khansa pambuyo pa opaleshoni.

Mankhwala a Chemotherapy

Ngati khansa yafalikira ku ziwalo zina za thupi lanu, dokotala wanu angakulangizeni kuti mulandire mankhwala a chemotherapy . Izi zimaphatikizapo kukupatsani mankhwala apadera ophera maselo a khansa. Mankhwalawa nthawi zambiri amaperekedwa kudzera m'mitsempha. Koma amathanso kuperekedwa ngati mapiritsi, madzi, kirimu wopaka pakhungu, kapena jakisoni.

Chithandizo cha Mankhwala Oyenera

Uwu ndi mankhwala atsopano. Amaphatikizapo kupereka mankhwala omwe amangoyang'ana majini ndi mapuloteni omwe amalamulira momwe maselo a khansa amakulira ndikugawikana. Izi zikutanthauza kuti maselo athanzi sangavulale kwambiri. Pali mitundu ingapo ya mankhwala omwe amagwiritsidwa ntchito pa izi. Dokotala wanu adzapanga dongosolo la chithandizo chapadera kutengera vuto lanu. Tazemetostat ndi mtundu wa mankhwala omwe amagwiritsidwa ntchito pa epithelioid sarcoma. Amathandiza kuchiza maselo a khansa omwe sangachotsedwe kwathunthu ndi opaleshoni.

Kodi izi zingalepheretsedwe kuchitika?

Chomvetsa chisoni n'chakuti, chifukwa epithelioid sarcoma nthawi zambiri imayamba popanda chifukwa chomveka, tilibe njira yoletsera kuti isakule . Izi zikutanthauza kuti n'zovuta kunena kuti, "Ngati muchita izi, sizingachitike."

Kodi chimachitika ndi chiyani ngati muli ndi epithelioid sarcoma? Kodi ingachiritsidwe?

Ndizachilendo kuchita mantha mukamva izi. Komabe, epithelioid sarcoma ndi matenda ochiritsika , makamaka ngati apezeka msanga . Dokotala wanu adzachita mayeso ena kuti aone kukula kwa chotupacho komanso ngati chafalikira kumadera ena. Kenako, adzapanga dongosolo la chithandizo lomwe likugwirizana ndi inu.

Pakhoza kukhala gulu la madokotala omwe akukuthandizani. Ena mwa iwo ndi awa:

• Dokotala wanu wamkulu ( dokotala amene nthawi zambiri amakuonani).
• Akatswiri a khansa: Izi zikuphatikizapo akatswiri a khansa ya mafupa, madokotala ochita opaleshoni ya khansa, ndi madokotala omwe amapereka chithandizo cha chemotherapy ndi radiation.
• Madokotala a khungu: Kwa mavuto a khungu.
• Akatswiri a matenda: Amene amaona malipoti a magazi anu ndi mayeso a biopsy ndikukupatsani tsatanetsatane.
• Akatswiri a zamaganizo: Anthu omwe amakuthandizani kuthana ndi nkhawa ndi mantha omwe amabwera chifukwa cha matenda ngati awa.

Njira yokhayo yochiritsira epithelioid sarcoma kwathunthu ndikuchotsa chotupacho ndi opaleshoni . Komabe, nthawi zina sizingatheke kuchichotsa kwathunthu.

Ngati dokotala sangathe kuchotsa chotupa chonsecho, dokotala wanu nthawi zambiri amalangiza njira zosiyanasiyana zochizira matenda anu. Popeza epithelioid sarcoma ndi khansa yomwe ikukula pang'onopang'ono, anthu ambiri omwe ali ndi matendawa akhoza kukhala ndi moyo wautali komanso wosangalala .

Pali malipoti ambiri ofufuza za kuchuluka kwa anthu omwe akupulumuka matendawa. Komabe, chifukwa ndi matenda osowa kwambiri, ziwerengero zimasiyana kwambiri. Malinga ndi malipoti ena, kuchuluka kwa anthu omwe apulumuka zaka zisanu kumayambira pa 25% mpaka 92%. Zimatengera zinthu zambiri, monga mtundu wa matendawa komanso momwe munthu amayankhira chithandizo.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati muwona chotupa chachilendo kapena kutupa kulikonse pathupi lanu, musachinyalanyaze. Onetsetsani kuti mwaonana ndi dokotala. Anthu omwe ali ndi epithelioid sarcoma nthawi zambiri amakhala ndi zotupa pamanja, m'manja, zala, m'miyendo yapansi, kapena pansi pa mapazi. Koma kumbukirani, zotupazi zimatha kufalikira kulikonse pathupi.

Ndi mafunso ati omwe muyenera kufunsa dokotala?

Ngati inu kapena wokondedwa wanu mwapezeka ndi epithelioid sarcoma, nayi mafunso ena omwe mungafunse dokotala wanu:

• Kodi chotupa chili kuti?
• Kodi ndili ndi chotupa chimodzi chokha? Kapena pali china?
• Kodi khansa yafalikira ku ziwalo zina za thupi?
• Kodi mumalimbikitsa chithandizo chanji?
• Kodi chithandizo changa chidzatenga nthawi yayitali bwanji?
• Kodi ndidzamva bwanji panthawi ya chithandizo? (Zinthu monga zotsatirapo zake)
• Kodi pali malo ena komwe ndingaphunzire zambiri za izi? (monga mawebusayiti odalirika, mabuku)

Ndizachibadwa kumva mantha, kukwiya, komanso kukhumudwa mukalandira matenda ngati awa. Lankhulani ndi dokotala wanu za zomwe mungayembekezere musanalandire chithandizo, panthawi yake, komanso mutalandira chithandizo. Zingakhalenso zothandiza kulankhula ndi mlangizi kapena katswiri wa zamaganizo. Angakuthandizeni kuthana ndi mavuto omwe mukukumana nawo panthawi ngati iyi. Ngati n'kotheka, lowani nawo gulu lothandizirana ndi anthu omwe akukumana ndi vuto lomweli. Izi zingakuthandizeni kuti musamadzimve kuti ndinu nokha.

Uthenga Wopita Nawo Kunyumba

• Epithelioid sarcoma ndi khansa yofewa yosowa kwambiri komanso yoopsa .
• Kawirikawiri ziphuphu m'miyendoZingawoneke ngati ziphuphu, nthawi zina ndi zilonda pakhungu.
• Zizindikiro sizingawonekere pachiyambi.
• Zimagwirizanitsidwa ndi vuto la jini lotchedwa SMARCB1 , koma chifukwa chenicheni sichinadziwikebe.
• Opaleshoni ndiyo njira yaikulu yothandizira . Chithandizo cha radiation, chemotherapy, ndi mankhwala ochizira matenda amagwiritsidwanso ntchito.
• N'zovuta kupewa , koma ngati zapezeka msanga, zimatha kuchiritsidwa .
• Ngati muwona chotupa chatsopano m'thupi lanu, pitani kwa dokotala nthawi yomweyo.
• Musachite mantha, musachite mantha, ndipo tsatirani malangizo oyenera a dokotala . Simuli nokha, pali madokotala ndi okondedwa anu oti akuthandizeni.

Kumbukirani, nkhaniyi ndi yongofuna kudziwa zambiri. Ngati muli ndi nkhawa iliyonse, ndi bwino kufunsa dokotala.