Kodi mukuyabwa ndi malo achilendo pakhungu lanu? Kungakhale matenda a Extramammary Paget's Disease (EMPD)!

Kodi munayamba mwaonapo kachidutswa kofiira, kokhala ndi mamba, nthawi zina kokhala ndi zilonda pakhungu lanu, makamaka m'mimba, m'khwapa, kapena m'malo oberekera? Kamawoneka ngati kakukula pang'onopang'ono, ndipo nthawi zina kumayabwa, sichoncho? Chabwino, lero tikambirana za vuto lapadera la khungu ngati limenelo. Madokotala amalitcha kuti Matenda a Extramammary Paget , kapena EMPD mwachidule. Ndikosowa pang'ono, koma ndikofunikira kudziwa.

Kodi Matenda a Extramammary Paget (EMPD) ndi chiyani?

Mwachidule, EMPD ndi matenda a pakhungu osowa kwambiri. Nthawi zina amatha kugwirizanitsidwa ndi mitundu ina ya khansa. Koma sizili choncho nthawi zonse. Ndi matenda omwe khungu lanu limakhala lofiira, lokhala ndi ziphuphu, kapena lotupa ndipo limakula. Nthawi zina limatha kukhala losapezeka kwa zaka zambiri matendawa atayamba.

Dzina lake limatchedwa "Matenda a Paget" potengera Sir James Paget, dokotala wanzeru wa ku Britain wa m'zaka za m'ma 1800. Dzina lake lagwiritsidwa ntchito pa mitundu ina yambiri ya khansa chifukwa cha zomwe adathandizira pa matenda. Mawu akuti "extramammary" amatanthauza "kunja kwa bere." Izi siziyenera kusokonezedwa ndi matenda a Paget a bere.

Akuti pakati pa 7% ndi 40% ya anthu omwe ali ndi matenda a Extramammary Paget akhoza kukhala ndi khansa ina . Komabe, monga ndanenera kale, EMPD si nthawi zonse chizindikiro cha matenda ena. Kulandira chithandizo msanga kungathandize kuchepetsa zizindikiro zanu ndikuthandizira kuzindikira khansa ina.

Kodi mitundu ikuluikulu ya ma EMPD ndi iti?

Pali mitundu iwiri ikuluikulu ya EMPDs:

1. EMPD Yoyamba: Iyi ndi vuto la pakhungu lomwe limachitika mwadzidzidzi. Limayamba pakhungu popanda chifukwa china chilichonse.

2. EMPD yachiwiri: Izi zimachitika chifukwa cha khansa yomwe ili mkati mwa thupi.

Ndani amene ali ndi mwayi waukulu wopeza EMPD?

Aliyense akhoza kukhala ndi EMPD, koma ndi yofala kwambiri m'magulu awa:

• Anthu azaka zapakati pa 50 ndi 80 .
• Chofala pakati pa akazi .
• Zingathenso kuwoneka pakati pa amuna aku Asia .
• Anthu oyera .

Koma ndikofunikira kukumbukira kuti vutoli ndi losowa kwambiri.

Nchifukwa chiyani EMPD iyi imachitika?

Kodi n’chiyani chimayambitsa EMPD yoyamba?

Kunena zoona, madokotala sakudziwabe chomwe chimayambitsa EMPD yoyamba. Amaganiza kuti ingayambe m'mitundu ina ya maselo m'thupi lathu. Mitundu iyi ya maselo ikuphatikizapo:

• Maselo a duct a Apocrine gland: Awa ndi ma duct a thukuta ndipo amapezeka pafupi ndi ma follicle a tsitsi.
• Maselo oyambira a Keratinocyte: Awa ndi maselo omwe amathandiza kukonza khungu.
• Maselo a Toker: Awa ndi maselo omwe amapezeka pakhungu ('minofu ya vulvar') yozungulira nipple ndi poyambira nyini.

Kodi n’chiyani chimayambitsa EMPD yachiwiri?

EMPD yachiwiri imayamba chifukwa cha khansa kwina kulikonse m'thupi. Khansa ya m'matumbo imanenedwa kuti ndiyo imayambitsa pafupifupi gawo limodzi mwa magawo atatu a milandu ya EMPD. Kuphatikiza apo, pali mitundu ina ya khansa yomwe ingayambitse EMPD yachiwiri:

• Khansa ya m'makoswe
• Khansa ya chikhodzodzo
• Khansa ya pachibelekero
• Khansa ya m'chiberekero
• Khansa ya prostate
• Khansa ya m'chiberekero

Kodi zizindikiro za EMPD ndi ziti?

Chizindikiro chachikulu cha EMPD ndi ziphuphu pakhungu zomwe zimaoneka ngati eczema . Kafukufuku wasonyeza kuti pafupifupi 65% ya odwala EMPD, zimachitika mozungulira maliseche , ndipo pafupifupi 20%, zimapezeka mozungulira maliseche .

Mukhoza kuona malo pakhungu lanu omwe ali ndi makhalidwe awa:

• Monga kutumphuka (`Crusty`)
• Yasanduka yofiira (`Yofiira`)
• Mamba

Madonthowo amakula pang'onopang'ono, ndipo amatha kukhala ndi m'mbali zosasinthasintha. Pamene EMPD ikupita patsogolo, zilonda zazikulu kapena timibulu tingayambe. Zizindikiro zina ndi izi:

• Kumva kutentha
• Khungu ndi lofiira ndipo limamva kukwiya .
• Kuyabwa
• Zowawa kapena zofewa
• Khungu lotupa (edema)

EMPD imapezeka kwambiri m'malo omwe ma glands anu otuluka thukuta (makamaka ma glands a khungu la apocrine) amapezeka. Imapezeka kwambiri mozungulira khomo la nyini. Itha kuchitikanso m'malo awa:

• Kuzungulira thako (`Anus`)
• Mbolo
• Perineum
• Chifuwa cha m'mimba

Kawirikawiri, EMPD imapezekanso m'zigawo zina za thupi, monga:

• Mimba
• Kwapa
• Mchombo
• Matako
• Khutu, chikope, nkhope kapena khungu la mutu
• Chifuwa chapansi
• Bondo kapena ntchafu

Ndikofunikira kudziwa kuti pafupifupi 10% ya anthu omwe ali ndi matenda a Paget akunja kwa mammary samakhala ndi zizindikiro zilizonse .

Kodi vuto la EMPD limeneli limapezedwa bwanji?

Choyamba, dokotala adzakufunsani za zizindikiro zanu ndikukuyesani thupi. Ngati akukayikira kuti muli ndi EMPD, adzachita izi:Kuyezetsa khungu kumachitika. Kuyezetsa khungu kumaphatikizapo kutenga chitsanzo chaching'ono cha khungu lanu ndikuchiyang'ana pansi pa maikulosikopu.

Akayang'ana pogwiritsa ntchito maikulosikopu, katswiri wa matenda amafufuza maselo apadera, akuluakulu, osazolowereka otchedwa "Maselo a Paget." Amazindikiranso maselo amenewa poyang'ana momwe amachitira ndi mankhwala osiyanasiyana (immunohistochemistry).

Kodi mumadziwa bwanji ngati muli ndi khansa ndi EMPD?

Mukapezeka ndi EMPD, dokotala wanu adzakuyesaninso kangapo kuti awone ngati muli ndi khansa yomwe ili mkati mwake. Mayesowa angaphatikizepo:

• Kujambula kwa Ultrasound (`Ultrasound`)
• Kuyezetsa bere (mammogram)
• Kupaka minofu ya pap
• Colonoscopy kapena proctoscopy
• Kujambula kwa CT
• Cystoscopy (kufufuza chikhodzodzo)
• Kuyezetsa kwa prostate
• Retrograde pyelogram (kufufuza impso ndi njira ya mkodzo)
• Ultrasound kapena singano biopsy ya ma lymph nodes
• Endoscopy yapamwamba (kufufuza pakhosi, m'mero, ndi m'mimba)

Kodi mankhwala a EMPD ndi ati?

Madokotala nthawi zambiri amachiritsa matenda a Paget ochokera kunja kwa mammary pogwiritsa ntchito opaleshoni.

• Opaleshoni ya Mohs: Mu njira iyi, dokotalayo amachotsa khungu lomwe lakhudzidwa ndi khungu ndi khungu, ndikusunga khungu lozungulira labwino.
• Kuduladula malo ambiri: Mu njira iyi, dokotala wa opaleshoni amachotsa malo a EMPD pamodzi ndi minofu yathanzi yozungulira. Kenako m'mphepete mwa bala amakokedwa.

Nthawi zina madokotala ochita opaleshoni amafunika kuchotsa malo akuluakulu a khungu ndi minofu ina. Anthu ena omwe ali ndi EMPD yozungulira vulva angafunike kuchotsedwa gawo kapena vulva yonse ('vulvectomy').

Taganizirani izi: Ngati simungathe kuchitidwa opaleshoni chifukwa cha matenda ena kapena thanzi lanu silili bwino, dokotala wanu angakulangizeni njira zina monga:

• Chithandizo cha Immunotherapy
• Kukonzanso khungu pogwiritsa ntchito laser
• Chithandizo cha Photodynamic (PDT)
• Chithandizo cha radiation
• Mankhwala ogwiritsidwa ntchito pochiza khansa (mankhwala ochepetsa poizoni)

Chofunika kwambiri ndichakuti ngati pali khansa yomwe ili mkati mwake, iyeneranso kuchiritsidwa padera.

Kodi pali njira yochepetsera chiopsezo cha matenda a EMPD?

Mwatsoka, palibe chomwe tingachite kuti tichepetse chiopsezo cha matenda a EMPD.

Kodi munthu amene ali ndi EMPD angayembekezere tsogolo lotani?

Mukalandira chithandizo cha EMPD, muyenera kupita kwa dokotala wanu kuti akakuoneninso. Izi zidalira komwe EMPD inali. Nthawi zambiri EMPD imabwereranso m'dera lomwelo lomwe idalandira chithandizo kale. Chifukwa chake, ndikofunikira kwambiri kupitiriza kutsatira malangizo a dokotala wanu.

Matenda a Extramammary Paget ndi osowa kwambiri pomwe amafalikira (metastasizes) ku ziwalo zina za thupi. Komabe, nthawi zina amatha kufalikira ku ma lymph nodes kapena ziwalo zina. Dokotala wanu angakuuzeni bwino zomwe zingatheke pa vuto lanu.

Kodi EMPD ingabwererenso ikachira?

Inde, EMPD ndi vuto lomwe lingabwerezedwenso ngakhale mutalandira chithandizo ndikuchira, ngakhale patatha zaka zambiri. Nthawi zina limatha kubwereranso patatha zaka zoposa 15. Ichi ndichifukwa chake madokotala amalimbikitsa kuyang'aniridwa kwa nthawi yayitali komanso kupimidwa pafupipafupi.

Ngati ndili ndi EMPD, ndimadzisamalira bwanji?

Chinthu chabwino kwambiri chomwe mungachite ndikupitiliza kupita kwa dokotala wanu kuti akakumane naye nthawi zonse. Ngati dokotala wanu akuwona zizindikiro za EMPD ikubwerera, akhoza kuyamba kulandira chithandizo nthawi yomweyo.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati muwona zizindikiro zatsopano za EMPD, pitani kwa dokotala nthawi yomweyo.

Ndizachibadwa kuchita mantha, manyazi, komanso kukhumudwa mukaona ziphuphu pakhungu kapena chotupa m'malo ovuta a thupi lanu, monga ziwalo zanu zoberekera. Matendawa, otchedwa Extramammary Paget's Disease (EMPD), nthawi zina amatha kusokonezedwa ndi matenda ena a pakhungu, kotero zingatenge nthawi kuti mudziwe bwino matendawa. Ngati pali khansa yomwe imayambitsa matendawa, EMPD ikhoza kukhala yoopsa kwambiri.

Komabe, nkhani yabwino ndi yakuti anthu ambiri omwe ali ndi EMPD amakhala ndi moyo wabwinobwino komanso wathunthu atalandira chithandizo. EMPD nthawi zambiri imachiritsidwa ndi opaleshoni. Ngati pali khansa yomwe ili mkati mwake, iyeneranso kuchiritsidwa. Popeza matenda a Extramammary Paget amatha kubwereranso, kupita kukawonana ndi dokotala nthawi zonse kungathandize kuzindikira msanga ngati abwereranso.

Zinthu zofunika kwambiri zomwe muyenera kukumbukira (Uthenga Wopita Nawo Kunyumba)

• EMPD ndi matenda a pakhungu omwe sapezeka kawirikawiri omwe angagwirizane ndi khansa.
• Samalani ndi mawanga ofiira, otupa, otupa, kapena otukumuka pakhungu, makamaka pafupi ndi ziwalo zoberekera, m'khwapa, kapena m'matako. Zizindikiro zake zingakhale kuyabwa, kutentha, ndi kupweteka.
• Ngati muwona chizindikiro chonga ichi , musachite manyazi kapena mantha, koma pitani kwa dokotala nthawi yomweyo.
• EMPD imapezedwa ndi biopsy ya khungu.
• Opaleshoni ndiyo njira yodziwika kwambiri yothandizira.
• Ndikofunikira kupitiliza kuyezetsa matenda, chifukwa EMPD ikhoza kubwereranso.
• Musadandaule, anthu ambiri omwe ali ndi EMPD amakhala bwino akalandira chithandizo. Chofunika kwambiri ndikupeza matendawa msanga ndikupeza chithandizo choyenera.

Ngati muli ndi mafunso ena okhudza izi, lankhulani ndi dokotala wanu. Iye angakupatseni upangiri woyenera kwa inu.

Matenda a Extramammary Paget, EMPD, matenda a pakhungu, khansa ya pakhungu, maselo a Paget, mawanga a pakhungu, kuyabwa, vulva, dera la perianal, matenda a pakhungu, opaleshoni ya Mohs