Kodi hormone ya GnRH ndi chiyani? Kodi imakhudza bwanji moyo wanu? (Gonadotropin-Releasing Hormone (GnRH))

Tonsefe timadutsa mu msinkhu. Ndi kusintha kwakukulu m'miyoyo yathu. Ndipo tikamaganiza zokhala ndi mwana, tikamalankhula za kusamba kwa mwezi kwa akazi, kodi mukudziwa za cholamulira chachinsinsi chomwe chili kumbuyo kwa zonsezi? Cholamulira chimenecho ndi mahomoni otchedwa GnRH. Ngakhale dzinali lingakhale lachilendo pang'ono, ichi ndi chinthu chofunikira kwambiri pakugwira ntchito kwa ziwalo zathu zoberekera. Lero, tiyeni tikambirane za mahomoni a GnRH awa ndi kufunika kwake m'thupi lathu.

Ndiye, kodi GnRH iyi ndi chiyani?

Mwachidule, GnRH ndi mahomoni omwe aliyense amapanga m'thupi lawo. Mukayamba kutha msinkhu muli aang'ono, kuchuluka kwa mahomoni amenewa kumawonjezeka. Izi zimapangitsa kuti mahomoni ena awiri ofunikira apangidwe : Follicle-Stimulating Hormone (FSH) ndi Luteinizing Hormone (LH) .

Mahomoni awiriwa, FSH ndi LH, ndi ofunikira kwambiri pa thanzi lathu lobereka. Amatchedwa gonadotropins. Mahomoni awa ndi omwe amachititsa kuti ma gonads athu azitha kukhwima bwino komanso kugwira ntchito bwino. Mwa akazi, ma gonads awa amatchedwa mazira . Mwa amuna, amatchedwa machende .

Mayina ena a GnRH

Dokotala wanu angagwiritse ntchito mayina ngati awa polankhula za homoni iyi:

• Luliberin
• Homoni yotulutsa mahomoni otchedwa luteinizing hormone (LHRH)

Kodi ntchito ya GnRH m'thupi la mkazi ndi yotani?

Mu njira yoberekera ya akazi, mahomoni otchedwa GnRH amakhudza mwachindunji kupanga mahomoni otchedwa estrogen ndi progesterone . Awa ndi mahomoni akuluakulu ogonana mwa akazi. Ma mahomoni amenewa ndi ofunikira kwambiri pa ovulation ndi kutenga pakati.

Izi ndi zomwe zimachitika pakati pa mwezi wanu wa msambo:

• Thupi lanu limatulutsa mtundu wina wa estrogen wotchedwa estradiol, womwe umawonjezera kupanga kwa GnRH.
• Chifukwa cha kuchuluka kwa GnRH, hormone ya FSH imachepa ndipo hormone ya LH imawonjezeka.
• Kusintha kumeneko kumapangitsa kuti dzira lituluke mu ovary. Izi timazitcha kuti ovulation .

Kodi chimachitika ndi chiyani kwa GnRH m'thupi la mwamuna?

Mu njira yoberekera ya amuna, hormone ya GnRH imalimbikitsa kupanga mitundu iwiri ikuluikulu ya mahomoni:

• Luteinizing hormone (LH): Izi zimatsimikizira kuchuluka kwa mahomoni achimuna otchedwa testosterone ndi androgens omwe amapangidwa m'thupi.
• Homoni yolimbikitsa follicle (FSH): Izi zimakhudza kupanga umuna.

Kodi hormone iyi ya GnRH imapangidwa bwanji m'thupi?

Dongosolo la endocrine la thupi lathu ndilo limapanga GnRH. Tangoganizirani, hormone ya GnRH imapangidwa ndi ma neuron mu hypothalamus muubongo wathu ndikutulutsidwa m'magazi. Kenako, hormone iyi imayenda m'magazi ndikupita ku pituitary gland yomwe ili pansi pa ubongo. Kenako, pituitary gland imalimbikitsidwa kupanga mahomoni a FSH ndi LH omwe tidakambirana kale ndikutulutsa m'magazi.

Ndi zinthu ziti zomwe zimakhudza kuchuluka kwa GnRH?

Milingo ya GnRH nthawi zambiri imakhala yotsika ali mwana. Imawonjezeka panthawi yaunyamata . Pambuyo pake, kuchuluka kwa GnRH kumayendetsedwa ndi mahomoni ogonana (testosterone, estrogen, ndi progesterone) m'matupi athu. Zili ngati njira yobwezera. Pamene kuchuluka kwa mahomoni ogonana kumawonjezeka, thupi limachepetsa kupanga GnRH. Pamene mahomoni ogonana amachepa, thupi limawonjezera kupanga GnRH. Koma pali kusiyana kumodzi pa izi. Ndi pamene akazi amatuluka dzira. Panthawiyo, GnRH ndi estradiol zonse zimawonjezeka.

Kodi chimachitika ndi chiyani ngati milingo ya GnRH ikukwera?

Ndikosowa kwambiri kuti GnRH ipangidwe mopitirira muyeso. Ngati milingo yake ili yokwera, pali chiopsezo chotenga matenda otupa otchedwa pituitary adenomas . Matumbowa angayambitse thupi kupanga mahomoni ambiri a FSH ndi LH. Zotsatira zake, milingo ya estrogen kapena testosterone m'thupi imatha kukwera kwambiri. Ngati milingo ya GnRH ili yokwera mwa ana, vuto lotchedwa kutha msinkhu msanga likhoza kuchitika.

Mavuto omwe amabwera ngati kuchuluka kwa GnRH kutsika

Kuchepa kwa GnRH kungayambitse mavuto osiyanasiyana kwa akazi ndi amuna. Tiyeni tiwone zomwe zili.

Kodi kuchuluka kwa GnRH kumayesedwa bwanji?

M'malo moyesa GnRH mwachindunji, nthawi zambiri imachitika poyesa kuchuluka kwa mahomoni a FSH ndi LH omwe amawalimbikitsa. Izi zimachitika ndi mayeso osavuta a magazi . Palibe chifukwa chosala kudya musanayese mayesowa. Komabe, kwa akazi omwe ali kusamba, dokotala wanu angakupempheni kuti muyese magazi awa tsiku linalake la msambo wanu.

Nthawi zina, mayeso oyambitsa GnRH amachitika kuti adziwe ngati pali vuto ndi kupanga GnRH. Izi ndi zomwe zimachitika:

1. Choyamba, dokotala wanu adzakuyezani magazi.

2. Kenako, hormone ya GnRH yopangidwa mu labu imaperekedwa kwa inu kaya ngati jakisoni kapena kudzera mu saline.

3. M'maola awiri otsatira, zitsanzo zingapo za magazi zimatengedwa pakapita mphindi 15-30.

4. Kenako mutha kupita kunyumba. Muyenera kubwerera patatha maola 24 ndikupereka magazi omaliza.

5. Kuchuluka kwa mahomoni ogonana a FSH, LH, ndi mahomoni ena ogonana m'magazi awa kumayesedwa mu labotale.

Nanga bwanji ngati pali zolakwika mu lipoti la mayeso?

Ngati zotsatira za mayesowa zili zapamwamba kwambiri kuposa zachizolowezi, izi zitha kukhala chizindikiro cha kutha msinkhu msanga. Dokotala wanu adzakufotokozerani izi mwatsatanetsatane.

Kodi timasunga bwanji dongosolo lathu la mahomoni kukhala lathanzi?

Pali zinthu zingapo zosavuta zomwe tingachite kuti dongosolo lathu la endocrine, kapena dongosolo la mahomoni, likhale lathanzi.

• Kuchita masewera olimbitsa thupi bwino: Khalani ndi thupi lochita masewera olimbitsa thupi osachepera masiku angapo pa sabata.
• Gonani mokwanira: Pezani kuchuluka koyenera kwa tulo komwe mukufunikira tsiku lonse.
• Khalani ndi kulemera koyenera: Idyani zakudya zopatsa thanzi zomwe zili ndi mafuta ochepa komanso cholesterol yochepa.
• Pewani kusuta: Ngati mumasuta fodya ndi kugwiritsa ntchito zinthu zopangidwa ndi fodya, funani thandizo kuti musiye. Nikotini ingakhale ndi zotsatirapo zoipa pa dongosolo lanu la mahomoni.
• Imwani mankhwala anu moyenera: Ngati muli ndi matenda okhudzana ndi mahomoni monga matenda a shuga kapena chithokomiro, imwani mankhwala anu monga momwe dokotala wanu wanenera.

Mankhwala okhudzana ndi GnRH (mankhwala)

Mu mankhwala, mankhwala amagwiritsidwa ntchito omwe amasintha momwe mahomoni a GnRH amagwirira ntchito. Izi zimatha kuletsa kupanga mahomoni (FSH, LH) omwe amalimbikitsa kupanga mahomoni ogonana kuchokera ku pituitary gland.

Kodi mankhwalawa amagwiritsidwa ntchito pa matenda otani?

Madokotala amagwiritsa ntchito mankhwala a GnRH awa pochiza khansa ya prostate mwa amuna. Amagwiritsidwanso ntchito pochiza matenda awa mwa akazi:

• Khansa ya m'mawere
• Endometriosis
• Kusabereka kwa akazi
• Kutuluka magazi ambiri m'mimba (Menorrhagia)
• Matenda a Premenstrual Dysphoric (PMDD)
• Matenda a uterine fibroids