Kodi muli ndi chotupa pa pituitary gland yanu? (Pituitary Adenoma) Tiyeni tiphunzire za icho!

Kodi nthawi zina mumadwala mutu popanda chifukwa? Kapena mumamva ngati maso anu akufooka pang'ono, ndipo simungathe kuwona zinthu kuchokera mbali bwino? Kapena, kodi muli ndi vuto lililonse chifukwa cha kusintha kwa mahomoni m'thupi lanu? Mwina chifukwa cha zinthuzi ndi chotupa chaching'ono chomwe chimayamba mu pituitary gland yanu. Lero, tikambirana mwatsatanetsatane za vutoli lotchedwa `Pituitary Adenoma` . Musadandaule, iyi si khansa.

Kodi pituitary adenoma ndi chiyani?

Mwachidule, pituitary adenoma ndi chotupa chosakhala khansa (chosaopsa) chomwe chimayamba mu pituitary gland yanu. Sichifalikira ku ziwalo zina za thupi monga khansa. Ndicho chinthu chofunikira kwambiri. Komabe, pamene adenoma iyi ikukula, imatha kukanikiza zinthu monga mitsempha ndi mitsempha yamagazi yozungulira. Pamenepo ndi pomwe zizindikiro zimayamba kuonekera.

Ndiye, kodi pituitary gland iyi ndi chiyani?

Tangoganizirani, kumbuyo kwa mphuno yathu, yolumikizidwa ku maziko a ubongo, ``Hypothalamus``, pali kachiwalo kakang'ono kofanana ndi nandolo. Ndicho chimene chimatchedwa pituitary gland. Ngakhale kuti ndi kakang'ono, kamagwira ntchito yofunika kwambiri m'thupi lathu. Kachiwalo aka kali ndi magawo awiri akuluakulu:

• Lobe Yam'mbuyo
• Lobe Yakumbuyo

Ziwalo zonsezi zimapanga ndikutulutsa mitundu yosiyanasiyana ya mahomoni m'magazi. Mahomoni ali ngati amithenga a mankhwala omwe amawongolera ndikuwongolera zochitika zosiyanasiyana m'thupi lathu. Amayenda m'magazi ndikupereka mauthenga ofunikira ku ziwalo zathu, minofu, ndi minofu ina. Nazi zina mwa mahomoni ofunikira omwe amapangidwa ndi pituitary gland:

• Homoni ya adrenocorticotropic (ACTH kapena Corticotropin)
• Homoni ya antidiuretic (ADH kapena Vasopressin)
• Homoni yolimbikitsa follicle (` FSH` )
• Homoni ya kukula (`GH`)
• Homoni ya luteinizing (`LH`)
• Oxytocin (` Oxytocin` )
• Prolactin
• Homoni yolimbikitsa chithokomiro (TSH)

Sikuti izi zokha, pituitary gland "imadziwitsanso" ma endocrine glands ena m'thupi lathu kuti apange mahomoni. Kotero mutha kumvetsetsa kuti ngati pali vuto ndi pituitary gland iyi, monga adenoma, ntchito ya hormone imodzi kapena mahomoni angapo ingakhudzidwe.

Kodi mitundu iyi ya adenomas imasiyanitsidwa bwanji?

Madokotala amagawa pituitary adenomas m'magulu awiri akuluakulu: 1. Kutengera ngati amapanga mahomoni kapena ayi:

• Kugwira Ntchito/Kutulutsa Adenoma:Kuphatikiza apo, mitundu iyi ya adenomas imapanga mahomoni amodzi kapena angapo a pituitary. Chifukwa chake, zizindikiro ndi matenda osiyanasiyana amatha kuchitika kutengera mahomoni omwe amapangidwa mopitirira muyeso.
• Ma adenoma osagwira ntchito/osatulutsa: Ma adenoma amenewa sapanga mahomoni. Komabe, ngati akukula, angayambitse zizindikiro mwa kukanikiza malo apafupi a ubongo kapena mitsempha . Uwu ndi mtundu wa adenoma womwe madokotala amakumana nawo nthawi zambiri.

2. Malinga ndi kukula:

• Microadenomas: Izi ndi zotupa zazing'ono kuposa mamilimita 10 (ndiko kuti, sentimita imodzi).
• Macroadenomas: Izi ndi zotupa zazikulu kuposa mamilimita 10. Macroadenomas ndi ofala kawiri kuposa ma microadenomas. Amakhalanso ndi mwayi waukulu woyambitsa kuchuluka kochepa kwa mahomoni amodzi kapena angapo a pituitary (vuto lotchedwa hypopituitarism).

Kodi izi zimaonedwa ngati chotupa cha muubongo?

Chiwalo cha pituitary kwenikweni ndi kapangidwe kake kamene kali m'thupi la munthu, ndipo kwenikweni si mbali ya ubongo. Chimalumikizidwa pansi pa ubongo. Komabe, madokotala amaona kuti pituitary adenomas ndi mtundu wa chotupa cha muubongo . Chotupa cha pituitary adenomas chimangokhala 10% yokha ya chotupa chachikulu cha muubongo.

Ndani amakumana ndi izi pafupipafupi? Kodi ndizofala bwanji?

Matenda a pituitary adenomas amatha kufalikira pa msinkhu uliwonse. Komabe, amapezeka kwambiri mwa anthu azaka za m'ma 30 ndi 40. Azimayi nawonso ali ndi mwayi wochuluka wochira matendawa kuposa amuna. Ndi ofala kwambiri kotero kuti ndi 10% mpaka 15% ya zotupa zonse zomwe zimamera mkati mwa chigaza. Malinga ndi ziwerengero, anthu pafupifupi 77 mwa 100,000 ali ndi vutoli. Komabe, ofufuza amakhulupirira kuti anthu ambiri, mwina okwana 20%, adzachira nthawi ina m'miyoyo yawo. Nthawi zambiri, makamaka omwe ali ndi ma microadenomas (`microadenomas`), alibe zizindikiro zilizonse, kotero sazindikirika.

Kodi zizindikiro za adenoma ya pituitary ndi ziti?

Zizindikiro za pituitary adenoma zimatha kusiyana kwambiri kuchokera kwa munthu ndi munthu. Zimatengera makamaka zinthu zingapo:

• Kaya adenoma imakula kukula ndikuwononga pituitary gland yokha, kapena ngati imayambitsa "mass effect" pa ziwalo zozungulira.
• Kodi ndi adenoma yotulutsa mahomoni ('functioning')? Ngati ndi choncho, zizindikiro zake zidzadalira mtundu wa mahomoni omwe amatulutsa.

Zizindikiro za `Mass Effect` zomwe zimayambitsidwa ndi `Macroadenomas` (zotupa zazikulu)

Ma adenoma akuluakulu (`Macroadenomas`) amayambitsa zizindikiro makamaka chifukwa cha kupsinjika kwa minofu yozungulira.

Tangoganizani, ngati muyika chinthu chachikulu m'chipinda chaching'ono, zimakhala ngati palibe malo okwanira oti zinthu zina zigwiritsidwe ntchito ndipo pali anthu ambiri.

• Mavuto a maso:

Pafupifupi 40% mpaka 60% ya anthu omwe ali ndi pituitary adenoma yayikuluKutaya masomphenya (kuona molakwika, kuona kawiri) kumachitika. Izi zimachitika chifukwa chakuti adenoma imakanikiza pa optic chiasm, yomwe imalumikiza maso ndi ubongo. Izi zingayambitse kutayika kwa masomphenya a m'mbali, makamaka m'mbali. Zili ngati kavalo amene wataya masomphenya ake mbali zonse ziwiri.

• Mutu :

Anthu ambiri omwe ali ndi pituitary adenomas amadandaula kuti mutu umapweteka pafupipafupi. Izi zitha kukhala chifukwa cha chotupa chomwe chimakankhira minofu yozungulira. Komabe, popeza mutu nthawi zambiri umayamba chifukwa cha zinthu zambiri, ukhozanso kuchitika chifukwa cha zinthu zina.

• Kusowa kwa mahomoni:

Ma adenoma akuluakulu (`Macroadenomas`) amatha kuwononga minofu ya pituitary gland ndikuchepetsa kupanga kwa mahomoni amodzi kapena angapo a pituitary. Matendawa amatchedwa `Hypopituitarism`. Zizindikiro zomwe zimachitika mahomoni onse akachepa zimasiyananso.

• Pamene mahomoni a LH ndi FSH achepa (`Hypogonadism`): Kuchuluka kwa ` Oestrogen` mwa akazi ndi ` Testosterone` mwa amuna kumachepa. Izi zingayambitse zizindikiro monga thukuta kwambiri, kuuma kwa nyini mwa akazi, ` Erectile Dysfunction` mwa amuna, kuchepa kwa kukula kwa tsitsi pankhope ndi m'thupi, kusintha kwa malingaliro mwa amuna onse awiri, kuchepa kwa chilakolako chogonana, komanso kutopa kwambiri.
• Pamene kuchuluka kwa mahomoni a TSH kumachepa (`Hypothyroidism`): Kuchuluka kwa mahomoni opangidwa ndi chithokomiro kumachepa. Izi zingayambitse zizindikiro monga kutopa, kudzimbidwa, kugunda pang'onopang'ono kwa mtima, khungu louma, kutupa kwa miyendo, ndi kusokonezeka kwa reflexes.
• Pamene hormone ya ACTH ili yochepa (`Adrenal Insufficiency`): Kupanga kwa hormone ya `Cortisol` m'thupi kumachepa. Izi zingayambitse zizindikiro monga kutsika kwa kuthamanga kwa magazi, nseru, kusanza, kupweteka m'mimba, komanso kusowa chilakolako cha chakudya.
• GH (Kusowa kwa mahomoni okula): Zizindikiro zimasiyana malinga ndi msinkhu. Akuluakulu amatha kutopa komanso kufooka kwa minofu.

Zizindikiro za adenomas yogwira ntchito

Kuwonjezera pa kutulutsa mahomoni amodzi kapena angapo, adenoma yogwira ntchito ingayambitse zizindikiro zosiyanasiyana ndi matenda okhudzana ndi mahomoni aliwonse.

• Ma prolactinoma (omwe amadziwikanso kuti Lactotroph Adenomas):

Matenda a adenoma amenewa amatulutsa mahomoni ambiri a prolactin . Matendawa amatchedwa hyperprolactinemia. Pafupifupi zilonda 4 mwa 10 za pituitary ndi zamtunduwu. Uwu ndiye mtundu wofala kwambiri wa pituitary adenoma.Pamene kuchuluka kwa prolactin kumawonjezeka, ntchito yachibadwa ya ziwalo zoberekera mwa akazi ndi amuna ikhoza kusokonekera.

• Kusabereka (kusabereka) kwa amuna ndi akazi.
• Kutuluka magazi ngati mkaka m'mabere ngakhale mutakhala kuti simuli ndi pakati (`Galactorrhea`).

• Matenda a Somatotroph Adenomas:

Ma adenoma amenewa amatulutsa mahomoni ochulukirapo (`Growth Hormone` kapena `Somatotropin`) . Pafupifupi 2 mwa 10 zotupa za pituitary ndi zamtunduwu. Zizindikiro zomwe zimayambitsidwa ndi izi zimasiyana ndi zaka.

• Akuluakulu: Matenda osowa koma oopsa otchedwa `Acromegaly` amapezeka. Pachifukwa ichi, mafupa ndi minofu ya thupi imakula modabwitsa. Pakapita nthawi, manja, mapazi, ndi mutu zimakula, ndipo mawonekedwe a nkhope amasintha. Zimakhudzanso kulamulira shuga m'magazi, ndipo minofu ya mtima imathanso kukula.
• Ana ndi achinyamata: Matenda otchedwa gigantism amapezeka. Amakula modabwitsa chifukwa cha kuchuluka kwa mahomoni okulira.

• Matenda a Corticotroph Adenomas:

Ma adenoma amenewa amatulutsa ACTH (adrenocorticotropic hormone) yochuluka kwambiri. Pafupifupi chotupa chimodzi mwa 10 cha pituitary ndi chamtunduwu. Homoni ya ACTH imalimbikitsa ma adrenal glands kuti apange mahomoni ambiri a steroid monga cortisol. Izi zimayambitsa Cushing's Syndrome (cortisol yochuluka).

• Kuthamanga kwa magazi kwambiri.
• Kufooka kwa minofu.
• Kutupa kosavuta.
• Mizere yofiirira (yoposa 1 cm) ('Stretch Marks') imawonekera pamimba.
• Matenda a mafupa.
• Kusweka kwa minofu.
• Matenda a shuga amtundu wachiwiri.

• Matenda a Thyrotroph Adenomas:

Ma adenoma amenewa amatulutsa TSH yochuluka (hormone yolimbikitsa chithokomiro) . Izi sizichitika kawirikawiri. TSH imalimbikitsa chithokomiro kuti chipange mahomoni ambiri a chithokomiro. Izi zimayambitsa `Hyperthyroidism` (vuto la chithokomiro chogwira ntchito mopitirira muyeso), zomwe zimafulumizitsa kagayidwe ka thupi m'thupi.

• Kuwonjezeka kwa kugunda kwa mtima.
• Kuchepetsa thupi popanda chifukwa chilichonse.
• Chimbudzi chotayirira pafupipafupi.
• Kutuluka thukuta.
• Kugwedezeka kwa manja.
• Nkhawa.

Chofunika: Pali zifukwa zina zambiri zomwe zimayambitsa hyperthyroidism. Kutupa kwa pituitary ndi chifukwa chosowa kwambiri.

• Matenda a Gonadotroph Adenomas:

Ma adenoma amenewa amapanga gonadotropins wochuluka (monga mahomoni a LH ndi FSH). Izi ndizosowa kwambiri.

• Izi zingapangitse akazi kukhala ndi nthawi yosakhazikika ya msambo komanso matenda monga Ovarian Hyperstimulation Syndrome (OHSS).
• Amuna amatha kuona zizindikiro monga kukula kwa machende, kuzama kwa mawu, kutayika kwa tsitsi (kumbuyo kwa makutu), komanso kukula msanga kwa tsitsi pankhope.
• Ana amathanso kutha msinkhu asanakwanitse zaka zobadwa.

Kodi ndi zinthu ziti zomwe zimayambitsa adenoma ya pituitary?

Asayansi sakudziwabe chomwe chimayambitsa ma adenoma amenewa. Komabe, ma adenoma ena amaganiziridwa kuti amagwirizana ndi kusintha kosayembekezereka (`masinthidwe`) m'majini (`DNA`) m'maselo athu. Kusintha kwa majini kumeneku kumapangitsa maselo mu pituitary gland kukula mofulumira ndikupanga chipolopolo. Kusintha kwa majini kumeneku nthawi zina kumatha kutengera kwa makolo kupita kwa ana (cholowa), kapena kumatha kukula mwachisawawa. Kuphatikiza apo, ma adenoma a pituitary amathanso kugwirizanitsidwa ndi matenda ena osowa a majini . Zitsanzo zina ndi izi:

• ``Multiple Endocrine Neoplasia type 1 (MEN1)``
• ``Multiple Endocrine Neoplasia type 4 (MEN4)``
• `Carney complex`
• Matenda a 'X-LAG'
• "Succinate dehydrogenase-related family pituitary adenoma"
• `Neurofibromatosis mtundu 1`
• "Von Hippel-Lindau syndrome"

Munthu amene ali ndi vutoli ali pachiwopsezo chachikulu chotenga matenda a pituitary adenoma. Komabe, ndikofunikira kukumbukira kuti anthu omwe alibe vuto lililonse la majini amathanso kutenga matenda amenewa.

Kodi madokotala amazindikira bwanji vutoli?

Njira yodziwira matenda a pituitary adenoma imasiyana malinga ndi mtundu wa adenoma yomwe muli nayo komanso ngati imayambitsa zizindikiro. Nthawi zambiri, munthu yemwe ali ndi adenoma yotulutsa mahomoni (`Functioning Adenoma`) amayamba kupezeka ndi kusalinganika kwa mahomoni (monga `Cushing's Syndrome`, `Acromegaly`) kutengera zizindikiro. Pokhapokha adenoma imapezeka pamene chifukwa chake chafufuzidwa. Izi zili choncho chifukwa matenda ambiri omwe amayamba chifukwa cha mahomoni ochulukirapo amatha kukhala ndi zifukwa zina kupatula pituitary adenomas. Zomwezo zitha kunenedwa za kusowa kwa mahomoni a pituitary (`Hypopituitarism`). Nthawi zina, pituitary adenoma imapezeka ngati `Incidental Finding` panthawi yowunikira mutu (`Image Test`) kuti adziwe vuto lina. Ma adenoma ambiri omwe amapezeka motere nthawi zambiri amakhala ang'onoang'ono komanso osagwira ntchito.

Ndi mayeso ati omwe amachitidwa pa izi?

Ngati dokotala wanu akukayikira kuti muli ndi pituitary adenoma, adzayang'anitsitsa zizindikiro zanu, mbiri yanu yachipatala, ndikukupimitsani thupi. Kuphatikiza apo, angakulangizeni chimodzi kapena zingapo mwa izi:

• Kuyezetsa Magazi: Kutengera ndi zizindikiro zanu, mayeso a magazi angapangidwe kuti awone kuchuluka kwa mahomoni osiyanasiyana a pituitary.
• Mayeso Ojambula: Kujambula mutu wa MRI (Magnetic Resonance Imaging) kapenaKujambula kwa `CT (Computed Tomography)` kungapangitse zithunzi zomveka bwino za kapangidwe ka mkati mwa mutu. Mayeso awa angatsimikizire ngati pali pituitary adenoma komanso kukula kwake. Mayeso a `MRI` ndiye mayeso oyenera komanso osavuta kugwiritsa ntchito pa izi.
• Kuyezetsa Maso: Ngati muli ndi vuto lililonse la masomphenya, dokotala wanu angakupatseni mayeso a masomphenya. Kuyezetsa kumeneku n'kofunika chifukwa ma adenoma akuluakulu a pituitary angayambitse mavuto a masomphenya mwa kukanikiza mitsempha ya maso, yomwe imagwirizanitsa maso ndi ubongo.

Kodi adenoma ya pituitary imachiritsidwa bwanji?

Pali njira zitatu zazikulu zochizira matenda a pituitary adenomas: opaleshoni, mankhwala, ndi chithandizo cha radiation. Nthawi zina njira imodzi kapena zingapo izi zingagwiritsidwe ntchito pamodzi. Popeza matenda a adenoma ndi mkhalidwe wa aliyense ndi zosiyana, inu ndi gulu lanu lachipatala mutha kugwira ntchito limodzi kuti mudziwe njira yochizira yomwe ili yoyenera kwa inu.

Opaleshoni yochotsa adenoma

Ngati muli ndi adenoma yomwe ikuyambitsa kusalingana kwa mahomoni kapena kusokoneza masomphenya anu, dokotala wanu angakulangizeni opaleshoni kuti muchotse adenoma yonse kapena gawo lake. Kutengera kukula kwa adenoma ndi kuopsa kwa zizindikiro zanu, opaleshoni yoposa imodzi ingafunike. Madokotala ochita opaleshoni nthawi zambiri amachita njirayi pogwiritsa ntchito njira yopangira opaleshoni yotchedwa `Transsphenoidal Surgery` . Izi zimaphatikizapo kudutsa mphuno ndi sphenoid sinus (malo opanda kanthu kumbuyo kwa mphuno, pansi pa ubongo) kuti akafike ku pituitary gland ndikuchotsa adenoma. Pafupifupi 95% ya zotupa za pituitary zimachotsedwa motere. Ndi njira yotetezeka. Komabe, ngati adenoma ndi yayikulu kwambiri kuti ichotsedwe kudzera mu mphuno kapena ili pamalo ovuta, dokotalayo angafunike kuchita opaleshoni ya transcranial. Iyi ndi njira yosowa kwambiri ya pituitary adenomas.

Chithandizo ndi mankhwala

Mitundu ina ya pituitary adenomas, makamaka prolactinomas , imatha kulamulidwa ndikuchepetsedwa ndi mankhwala. Anthu omwe ali ndi prolactinomas (awa ndi omwe amapezeka kwambiri) poyamba amalandira chithandizo ndi dopamine agonist, monga Cabergoline (Dostinex®) kapena Bromocriptine (Cycloset®), kwa miyezi ingapo.

Nkhani yabwino ndi yakuti pafupifupi 80% ya milandu, mankhwalawa amachepetsa prolactinoma ndikubwezeretsa kuchuluka kwa mahomoni a prolactin kukhala kwabwinobwino.

Ngati mankhwala sakugwira ntchito kapena ngati ndi mtundu wina wa adenoma, dokotala wanu angakulangizeni opaleshoni.

Chithandizo cha X-ray

Chithandizo cha radiation chimagwiritsa ntchito ma X-ray amphamvu kwambiri kuti awononge maselo a adenoma, kuchepetsa chotupacho kapena kuchiletsa kukula kwake.(monga `Gamma Knife`®) Njira yapadera komanso yolondola kwambiri yochizira pogwiritsa ntchito radiation imagwiritsidwa ntchito. Pachifukwa ichi, ma radiation angapo amalunjika ku adenoma kuchokera mbali zosiyanasiyana, kuchepetsa kuwonongeka kwa minofu yathanzi yozungulira. Njirayi imagwiritsidwa ntchito m'malo otsala pambuyo pa opaleshoni kapena ngati opaleshoni singatheke.

Kodi zotsatirapo zake ndi ziti?

Monga momwe zimakhalira ndi chithandizo chilichonse chamankhwala, chithandizo cha pituitary adenoma chingakhale ndi zotsatirapo zina.

• Pambuyo pa opaleshoni ndi/kapena chithandizo cha radiation, pafupifupi 60% ya anthu omwe ali ndi pituitary adenomas amatha kukhala ndi `Hypopituitarism` (kuchepa kwa kupanga mahomoni amodzi kapena angapo a pituitary). Ngakhale kuti izi ndi vuto la moyo wonse, mankhwala olowa m'malo mwa mahomoni angathandize anthu kukhala ndi moyo wabwinobwino.
• Mavuto omwe angakhalepo chifukwa cha opaleshoni:
• Kutuluka magazi.
• Kutuluka kwa madzi m'mphuno (Cerebrospinal Fluid (CSF)) (madzi amadzi ochokera m'mphuno).
• Meningitis (matenda a nembanemba zomwe zimaphimba ubongo).
• Matenda a shuga a insipidus (kukodza kwambiri ndi ludzu lochuluka chifukwa cha kusowa kwa mahomoni oletsa kukodza m'mimba).
• Zotsatira zoyipa zomwe zimapezeka kawirikawiri za mankhwala a dopamine agonist a prolactinoma ndi monga: mutu, nseru, kusanza, chizungulire, komanso nthawi zina khalidwe lokakamiza.
• Zotsatirapo zomwe zingakhalepo chifukwa cha chithandizo cha radiation:
• Kusowa kwa mahomoni a pituitary (kungathe kuchitika pakapita nthawi).
• Kusabereka bwino.
• Kutaya masomphenya ndi kuwonongeka kwa minofu ya ubongo (kawirikawiri).
• Chotupa china chingayambike pamalo omwewo patatha zaka zambiri kuchokera pamene chithandizo chachitika (chosowa kwambiri).

Kodi kupangika kwa ma adenomas awa kungalepheretsedwe?

Mwatsoka, palibe chomwe mungachite kuti mupewe matenda a pituitary adenomas. Nthawi zambiri, amapezeka mwachisawawa. Komabe, akhoza kugwirizanitsidwa ndi matenda ena osowa a majini omwe atchulidwa kale. Ngati wachibale wapafupi (mchimwene, mlongo, kapena kholo) ali ndi vuto la majini ngati ili, mutha kulankhula ndi dokotala wanu za upangiri ndi kuyezetsa majini kuti muwone ngati nanunso muli ndi vutoli. Ngati muli nalo, dokotala wanu akhoza kukuyang'anirani mosamala ndikupeza ndi kuchiza matenda aliwonse a pituitary omwe amayamba msanga.

Kodi zizindikiro za matendawa ndi ziti?

Chiyembekezo cha adenoma ya pituitary, kutanthauza kuti, kuchira kwanu ndi thanzi lanu lamtsogolo, zimadalira kukula ndi mtundu wa adenoma, komanso chithandizo chomwe mumalandira .

Nkhani yabwino ndi yakuti nthawi zambiri, adenoma ikachotsedwa kwathunthu kapena kuthetsedwa ndi chithandizo, odwala amatha kukhalanso ndi moyo wathanzi komanso wathunthu.

Nthawi zina, chithandizo chingachepetse kupanga mahomoni kudzera mu pituitary gland. Ngati izi zitachitika, mungafunike kumwa mankhwala olowa m'malo mwa mahomoni kwa moyo wanu wonse kuti mulowe m'malo mwa mahomoni ochepetsedwawo. Nthawi zina ma adenoma amatha kubwereranso. Izi zikutanthauza kuti angafunike kuthandizidwanso pakapita nthawi. Ziwerengero zikusonyeza kuti pafupifupi 18% ya anthu omwe ali ndi ma adenoma osagwira ntchito komanso pafupifupi 25% ya anthu omwe ali ndi prolactinoma angafunikenso chithandizo mtsogolo. Chifukwa chake, ndikofunikira kwambiri kukhala ndi nthawi yokumana ndi dokotala wanu ndikupita kukayezetsa nthawi zonse.

Kodi n'zotheka kukhala ndi pituitary adenoma?

Inde, mungathe. Ngati pituitary adenoma ndi yaying'ono ndipo siimayambitsa zizindikiro zilizonse, mutha kukhala nayo bwino. Ndipotu, anthu ambiri amapeza kuti ali ndi adenoma akangoyesedwa mutu pazifukwa zina. Komabe, ngati adenoma ikupitiriza kukula kapena ikuyamba kuyambitsa zizindikiro, mudzafunika chithandizo. Ngati muli ndi pituitary adenoma yayikulu komanso/kapena yogwira ntchito (yopanga mahomoni), mudzafunika chithandizo. Izi zili choncho chifukwa ma pituitary adenoma ena amatha kukhudza kwambiri thanzi lanu komanso moyo wanu.

Ndi mavuto otani omwe angachitike ngati sanachiritsidwe?

Ngati sanalandire chithandizo, ma adenoma ena a pituitary - makamaka ma adenoma akuluakulu (`Macroadenomas`) ndi ma adenoma ogwira ntchito (`Secreting`) - angayambitse mavuto aakulu azaumoyo . Mavutowa amadalira kwambiri mtundu wa mahomoni omwe amatulutsa adenoma (tidakambirana izi koyambirira mu gawo la 'Zizindikiro'). Vuto losowa kwambiri koma loopsa kwambiri la ma adenoma a pituitary omwe sanalandire chithandizo ndi 'Pituitary Apoplexy'. Iyi ndi 'Yadzidzidzi Yachipatala'. Izi zimachitika pamene magazi akutuluka mkati kapena kunja kwa pituitary gland. 'Pituitary Apoplexy' nthawi zambiri imayamba chifukwa cha kutuluka magazi mu pituitary adenoma. Chotupacho chimakula mwadzidzidzi, ndikuwononga pituitary gland. Adenoma ikakula, chiopsezo chotenga 'Pituitary Apoplexy' chimakhala chachikulu. Zizindikiro za 'Pituitary Apoplexy' nthawi zambiri zimawonekera mwachangu kwambiri ndipo zimatha kupha . Zizindikiro zazikulu ndi izi:

• Mutu wopweteka kwambiri (monga mutu woopsa kwambiri womwe ndidakumana nawo m'moyo wanga).
• Kuona kawiri kapena kulephera kukweza chikope chifukwa cha kulephera kugwira ntchito kwa minofu ya maso.
• Kutaya masomphenya a mbali kapena kutaya masomphenya kwathunthu m'diso limodzi kapena onse awiri.
• Kulephera kugwira ntchito bwino kwa adrenal kumayambitsa kutsika kwa kuthamanga kwa magazi, nseru, ndi kusanza.
• Kusintha kwa umunthu (monga kusokonezeka) chifukwa cha kuchepa mwadzidzidzi kwa mtsempha wa ubongo wa anterior mu ubongo.

Matenda a pituitary apoplexy ndi matenda osowa kwambiri, koma ndi oopsa kwambiri. Ngati mukukumana ndi chimodzi mwa zizindikiro izi, imbani chithandizo chamankhwala chadzidzidzi (monga 911) nthawi yomweyo kapena pemphani wina kuti akutengereni kuchipatala chapafupi.

Kodi muyenera kupita kwa dokotala liti?

• Ngati muli ndi vuto lililonse la masomphenya (kusawona bwino, kuwona kawiri, kuchepa kwa masomphenya ozungulira) ndi/kapena mutu wopweteka womwe umapitirira kapena wobwerezabwereza (makamaka pamphumi), onani dokotala ndi kuwauza za vutoli.
• Ngati mwapezeka kale ndi vuto la pituitary adenoma, muyenera kuonana ndi dokotala nthawi zonse kuti muwone momwe vuto la adenoma lilili komanso kuti muwonetsetse kuti chithandizocho chikugwira ntchito bwino.

Pomaliza, kumbukirani zinthu izi:

Ndizachilendo kumva mantha komanso nkhawa mukazindikira kuti muli ndi chotupa. Komabe, nkhani yabwino yokhudza pituitary adenomas ndi yakuti nthawi zambiri (oposa 99%) si khansa (yoipa) ndipo nthawi zambiri, chithandizo chingapangitse zotsatira zabwino kwambiri. Kumbukirani, dokotala wanu ndiye mnzanu wokuthandizani kuti mukhale ndi thanzi labwino. Chifukwa chake, musazengereze kuuza dokotala wanu za zizindikiro zilizonse, kusasangalala, kapena mafunso omwe mungakhale nawo okhudza chithandizo chanu. Ndi chidziwitso choyenera komanso chithandizo cha panthawi yake, mutha kuthana ndi vutoli bwino.