Matenda a kuvutika maganizo si ophweka monga momwe akuonekera. Kukhala ndi vutoli nthawi zambiri kumakhala kovuta. Zimatenga nthawi kuti anthu ena apeze chithandizo choyenera. Nthawi zina, mankhwala amodzi sangapereke mpumulo wathunthu. Pali chifukwa chake. Tiyeni timvetse izi kuyambira pachiyambi.
Kodi n’chifukwa chiyani kuvutika maganizo kumachitika? Kodi mankhwala ngati Rexulti angathandize bwanji?
Mwachidule, mu Major Depression Disorder (MDD), kuchuluka kwa mankhwala ena muubongo wathu kumachepa. Timatcha ma neurotransmitters awa. Mwina mudamvapo za serotonin ndi dopamine . Awa ndi mankhwala akuluakulu omwe amalamulira zinthu monga momwe timaganizira, kukonzekera, kukhala osangalala, kumvetsera, komanso kugona. Chifukwa chake izi zikachepa, zizindikiro za kuvutika maganizo zimawonekera.
Mankhwala oletsa kuvutika maganizo nthawi zambiri amaperekedwa kuti athandize kubwezeretsa kuchuluka kwa mankhwala amenewa. Koma nthawi zina, ngakhale kuti mankhwalawa amatha kuchepetsa zizindikiro, amatha kusiya zizindikiro zomwe zimakhala zovuta kwambiri kuti zigwire ntchito tsiku ndi tsiku. Anthu ena amangoyankha pang'ono chithandizo. Izi zimatchedwa kuvutika maganizo kosachiritsika ndi chithandizo.
Apa ndi pamene madokotala amawonjezera mankhwala ena ku mankhwala omwe alipo. Izi zimatchedwa chithandizo chowonjezera . Izi zikutanthauza kuti, mankhwala omwe amaperekedwa kuti "athandize" chithandizo chomwe chilipo, kuti "awonjezere" kugwira ntchito kwake.
Rexulti (brexpiprazole) ndi imodzi mwa mankhwala owonjezera. Mankhwalawa ali m'gulu la mankhwala otchedwa antipsychotics a m'badwo wachiwiri. Mankhwala atsopanowa ali ndi zotsatirapo zochepa, monga kunjenjemera, kuuma kwa minofu, ndi kunenepa, poyerekeza ndi mankhwala akale. Rexulti imagwira ntchito polamulira mankhwala a muubongo mwanjira ina, kuchepetsa zizindikiro komanso kuchepetsa chiopsezo cha zotsatirapo zoyipa.
Kodi Rexulti imagwira ntchito bwanji m'thupi?
Rexulti imagwira ntchito makamaka powonjezera kuchuluka kwa dopamine ndi serotonin muubongo. Makamaka, mankhwalawa amamangirira ku ma receptors ena muubongo ndipo amathandiza kutulutsa dopamine yomwe yagwidwa. Amathandizanso kuti serotonin igwire ntchito, yomwe ingathandize kusintha maganizo ndikuchepetsa zizindikiro za kuvutika maganizo.
Kodi ndiyenera kugwiritsa ntchito bwanji mankhwalawa?
Rexulti ndi piritsi lomwe mumamwa kamodzi patsiku. Likhoza kumwedwa ndi chakudya kapena ayi. Nthawi zambiri limayamba ndi mlingo wochepa kwambiri, pafupifupi theka la milligram (0.5mg). Dokotala wanu adzawonjezera pang'onopang'ono mlingo kutengera momwe thupi lanu limayankhira, mankhwala ena omwe mukumwa, komanso momwe impso zanu kapena chiwindi chanu chikugwirira ntchito. Mlingo waukulu wa kuvutika maganizo ndi 3 milligrams (3mg) patsiku.
Chofunika kwambiri ndikutsatira malangizo a dokotala wanu molondola. Kumwa mankhwala anu panthawi yoyenera tsiku lililonse ndiyo njira yokhayo yochepetsera mayendedwe a ubongo wanu, kuwongolera zizindikiro zanu, ndikugwira ntchito bwino.
Kumbukirani kuti mankhwalawa sakuchiritsani nthawi yomweyo. Zingatenge milungu ingapo kuti zizindikiro zanu zisinthe. Chifukwa chake, kugwiritsa ntchito mankhwalawa nthawi zonse ndiye chinsinsi cha kupambana.
Kodi maphunziro amanena chiyani za kupambana kwa mankhwalawa?
Kafukufuku awiri akuluakulu achitika kuti adziwe momwe Rexulti ilili yothandiza komanso yotetezeka pochiza kuvutika maganizo. Mu kafukufukuyu, gulu limodzi la anthu linapatsidwa Rexulti ndipo gulu lina linapatsidwa placebo. Izi zinathandiza ofufuza kuyeza zotsatira zenizeni za mankhwalawa.
Malinga ndi zotsatira za kafukufukuyu, patatha milungu 6, anthu ambiri omwe adamwa Rexulti kuwonjezera pa mankhwala awo oletsa kuvutika maganizo anali ndi zizindikiro za kuvutika maganizo pang'ono kapena pang'ono.
Gome ili m'munsimu likuwonetsa zotsatira zake. Ziwerengero zikachepa, zizindikiro zimakhala zoopsa kwambiri.
| Gulu | Mulingo wa kuvutika maganizo pachiyambi (chiwerengero chapakati) | Mulingo wa kuvutika maganizo pambuyo pa masabata 6 (chiwerengero chapakati) | Kusiyana kwa zigoli (kusintha) |
|---|---|---|---|
| Phunziro 1: Placebo (piritsi lopanda pake) | 27.3 | 22.1 | -5.2 |
| Phunziro 1: Rexulti 2 mg | 26.9 | 18.5 | -8.4 |
| Phunziro 2: Placebo (piritsi lopanda pake) | 26.5 | 20.2 | -6.3 |
| Phunziro 2: Rexulti 1 mg | 26.5 | 18.9 | -7.6 |
| Phunziro 2: Rexulti 3 mg | 26.5 | 18.2 | -8.3 |
Monga mukuonera kuchokera m'maphunzirowa, omwe adamwa Rexulti adasintha kwambiri zizindikiro zawo. Maphunziro awa adatsimikiziranso kuti kuthekera kwawo kuchita zinthu tsiku ndi tsiku, ndi banja, m'gulu, komanso kuntchito/kusukulu, kudakula.
Ndingadziwe bwanji ngati mankhwalawo akugwira ntchito?
Pakatha milungu kapena miyezi ingapo, mudzayamba kuona kusintha kwakukulu kwa zizindikiro zanu. Banja lanu ndi anzanu adzaonanso kusiyana kwanu.
- Kusintha kwa maganizo
- Mphamvu zambiri kapena chilimbikitso
- Kugona bwino
- Chidwi ndi zochita zomwe munkasangalala nazo kale.
- Kuchepetsa nkhawa kapena nkhawa
- Kuwonjezeka kwa njala
- Kuganizira bwino
Kusintha kumeneku sikuchitika mwadzidzidzi. Kumachitika pang'onopang'ono. Chifukwa chake, ndikofunikira kutsatira kusintha kwa zizindikiro zanu. Nthawi yomwe muyenera kumwa mankhwala imasiyana malinga ndi munthu. Anthu ena amafunikira chithandizo kwa nthawi yochepa, pomwe ena amafunikira kwa nthawi yayitali.
Chofunika kwambiri ndichakuti musasiye kumwa mankhwala anu popanda kulankhula ndi dokotala wanu chifukwa mukuganiza kuti zizindikiro zanu zikuchepa. Ngati mutatero, zizindikiro zanu zitha kubwereranso. Ngati simukumva bwino patatha miyezi ingapo, uzani dokotala wanu za zimenezo.
Zotsatirapo zake ndi momwe mungathanirane nazo?
Zotsatira zoyipa kwambiri za Rexulti ndi kunenepa kwambiri, kugona tulo, chizungulire, zizindikiro zofanana ndi chimfine, komanso kusakhazikika (kulephera kukhala chete). Izi sizichitika kwa aliyense, koma nthawi zambiri zimachepa pakapita nthawi.
| Zotsatira zoyipa | Zimene mungachite |
|---|---|
| Kulemera, kuchuluka kwa cholesterol/shuga | Khalani ndi moyo wathanzi. Muzichita masewera olimbitsa thupi, onjezerani ndiwo zamasamba, zipatso, ndi nyama zopanda mafuta ambiri muzakudya zanu. Chepetsani mafuta, mchere, ndi shuga. Dokotala wanu nthawi zonse amayesa kulemera kwanu, kuthamanga kwa magazi, cholesterol, ndi shuga. |
| Kugona kapena chizungulire | Ngati mukumva tulo, imwani mankhwala musanagone usiku. Dzukani pang'onopang'ono kuchokera pamene mukukhala kapena kugona. Pewani kuyendetsa galimoto mpaka mutadziwa momwe mankhwalawa akukukhudzirani. |
| Kusakhazikika (Akathisia) | Izi zikutanthauza kumva ngati simungathe kukhala pamalo amodzi ndikungoyendayenda. Zochita zopepuka monga kuyenda ndi kutambasula zingathandize. Khazikitsani maganizo anu ndi zinthu monga kupuma ndi kusinkhasinkha. Chepetsani zinthu monga khofi, tiyi, ndi cola, chifukwa zimatha kuwonjezera kumverera kumeneku. |
| Kusalolera kutentha | Mankhwalawa angachepetse mphamvu ya thupi yodziziziritsa lokha. Pewani kutentha kwambiri komanso kusowa madzi m'thupi. Valani zovala zopepuka ndipo imwani madzi ambiri. |
| Kupweteka m'mimba, kudzimbidwa, pakamwa pouma | Imwani mankhwalawa pamodzi ndi chakudya. Ngati pakamwa panu pauma, imwani madzi pang'ono pafupipafupi, yamwani madzi oundana, kapena kutafuna chingamu chopanda shuga. Ngati mukutsekula m'mimba, imwani madzi ambiri ndipo idyani zakudya zokhala ndi ulusi wambiri (tirigu, nyemba, zipatso). |
Izi ndi zinthu zomwe zimachitika kawirikawiri. Ngati vuto lililonse mwa izi likupitirira kapena likuipiraipira, onetsetsani kuti mwadziwitsa dokotala wanu.
Kodi pangakhale mavuto ndi mankhwala ena? (Kuyanjana kwa mankhwala)
Inde. Mankhwala ena amatha kuwonjezera kapena kuchepetsa mphamvu ya Rexulti, kapena kuwonjezera chiopsezo cha zotsatirapo zoyipa, akamwedwa ndi Rexulti. Mwachitsanzo, mankhwala ena opha tizilombo toyambitsa matenda (monga ketoconazole), maantibayotiki ena (monga clarithromycin), mankhwala ena oletsa kuvutika maganizo (monga fluoxetine, paroxetine), komanso madzi a mphesa amatha kusintha zotsatira za Rexulti.
Choncho, ndikofunikira kwambiri kuuza dokotala wanu za mankhwala onse, mavitamini, ndi mankhwala azitsamba omwe mukumwa, kuti athe kusintha mlingo wa Rexulti kuti ugwirizane ndi inu.
Ndi mayeso ati omwe ayenera kuchitidwa panthawi ya chithandizo?
Dokotala wanu adzakuyesani mayeso kuti aone momwe thanzi lanu lilili musanayambe kumwa mankhwalawo komanso pamene mukumwa.
- Kulemera kwanu, kutalika kwanu, ndi kuzungulira kwa chiuno chanu.
- Kuchuluka kwa magazi (CBC).
- Kuyesa cholesterol m'magazi ndi shuga (Kuyesa mafuta m'thupi ndi shuga m'magazi).
- Kuthamanga kwa magazi.
- Mayeso a AIMS kuti aone ngati pali mayendedwe osazolowereka (monga, mayendedwe osadzifunira a miyendo).
Mayeso awa ndi njira yokhayo yodziwira momwe mankhwalawo angakhudzire thupi lanu.
Uthenga Wopita Nawo Kunyumba
- Rexulti ndi mankhwala "owonjezera" omwe amaperekedwa kuwonjezera pa mankhwala omwe akumwa kale pochiza kuvutika maganizo, kuti awonjezere mphamvu zawo.
- Izi zimagwira ntchito pogwirizanitsa mankhwala omwe ali muubongo omwe amagwirizana ndi chisangalalo ndi chisangalalo.
- Imwani mankhwala nthawi zonse, pa mlingo wovomerezeka, monga momwe dokotala wanu wanenera.
- Ngakhale zizindikiro zanu zitayamba kuchepa, pewani kusiya kumwa mankhwala popanda kufunsa dokotala.
- Dziwani zotsatirapo zake monga kunenepa kwambiri, kugona tulo, komanso kusakhazikika. Ngati zikukuvutitsani, lankhulani ndi dokotala wanu.
- Ndikofunikira kudziwitsa dokotala wanu za mankhwala ena onse, mavitamini, ndi mankhwala achikhalidwe omwe mukumwa.
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