Kodi muli ndi ziphuphu kapena mabala osadziwika pathupi lanu? Zingakhale Schwannomatosis!

Kodi nthawi zina mumamva kupweteka kosalekeza m'thupi lanu? Kapena nthawi zina mumamva ziphuphu zazing'ono pansi pa khungu lanu? Ngakhale kuti sitisamala kwambiri zinthuzi, nthawi zina zimakhala zizindikiro za matenda. Lero, tikambirana za matenda omwe samveka kawirikawiri, koma ndi ofunikira kudziwa. Umenewo ndi matenda otchedwa `Schwannomatosis`.

Kodi `Schwannomatosis` ndi chiyani? Tiyeni timvetse mosavuta!

Mwachidule, Schwannomatosis ndi vuto lomwe limabwera chifukwa cha kusintha kwa majini athu. Apa ndi pamene zotupa (zotupa) zimakula mu dongosolo la mitsempha la thupi lathu, ndiko kuti, mu mitsempha. Timatcha zotupa izi kuti `schwannomas`. `schwannomas` izi zimachokera ku mtundu wapadera wa selo womwe umazungulira mitsempha yathu ndipo umagwira ntchito ngati choteteza. Maselo awa amatchedwa `maselo a Schwann`. Amapezeka makamaka mu dongosolo lathu la mitsempha - ndiko kuti, mu mitsempha yomwe imachokera ku ubongo ndi msana, mu mizu ya mitsempha, komanso komwe mitsempha imalumikizana ndi minofu.

Schwannomatosis ndi matenda omwe nthawi zambiri amakhala ndi ululu wosatha kwa achinyamata azaka zapakati pa 20 ndi 40. Ndi mtundu wina wa neurofibromatosis, gulu la zotupa zomwe zimapangidwa mu dongosolo la mitsempha.

Kodi pali mitundu ya Schwannomatosis?

Inde, pali mitundu ikuluikulu ingapo ya Schwannomatosis. Izi zimagawidwa m'magulu malinga ndi mtundu wa majini womwe umayambitsa mtundu uliwonse. Mitundu iyi ndi iyi:

• `NF2` - `schwannomatosis` yokhudzana ndi matendawa (yomwe kale inkatchedwa `neurofibromatosis type 2`).
• `SMARCB1` - yokhudzana ndi `schwannomatosis`.
• `LZTR1` - yokhudzana ndi `schwannomatosis`.
• `22q` - `schwannomatosis` yokhudzana ndi izi (izi zimachitika chifukwa cha kusintha kwa gawo la chromosome 22).
• Schwannomatosis sinatchulidwe mwanjira ina (NOS).
• Schwannomatosis yomwe siili m'gulu lina (NEC).

Ngakhale mayina awa angawoneke ovuta pang'ono, kuwaika m'magulu motere ndi thandizo lalikulu kwa madokotala pozindikira matendawa molondola ndikupereka upangiri woyenera.

Kodi vuto limeneli lotchedwa `Schwannomatosis` ndi losowa bwanji?

Schwannomatosis ndi mtundu wosowa kwambiri wa neurofibromatosis. Ziwerengero zenizeni za anthu omwe ali ndi matendawa zimasiyana. Kafukufuku wina akusonyeza kuti schwannomatosis yokhudzana ndi NF2 ingakhudze pafupifupi munthu m'modzi mwa anthu 30,000 . Mitundu ina ikaphatikizidwa, imakhudza pafupifupi munthu m'modzi mwa anthu 70,000 .

Si aliyense amene ali ndi schwannoma amene ali ndi schwannomatosis. Mu schwannomatosis, ma schwannomas ambiri amapangidwa. Kawirikawiri, schwannoma imodzi ndi yofala kwambiri kuposa multiple schwannomatosis. Izi zikutanthauza kuti sizichitika kwa anthu ambiri.

Kodi zizindikiro za Schwannomatosis ndi ziti?

Chizindikiro chachikulu komanso chofala kwambiri chomwe chimapezeka mu vutoli ndi ululu . Ululuwu umachitika chifukwa chotupa cha schwannoma chikukanikizira mitsempha ndi minofu yozungulira. Kodi ululuwu ungakhale wotani?

• Kungakhale kupweteka kosatha , kutanthauza kuti kumatha kwa miyezi ingapo, ngakhale zaka.
• Mtundu wa ululu ukhoza kukhala wochepa mpaka wovuta .
• Ululu uwu umamveka kulikonse m'thupi , osati komwe kuli chotupacho chokha. Nthawi zina, ululuwu ukhoza kuchitika pamalo omwe sakugwirizana ndi komwe chotupacho chili.
• Ululu ukhoza kuwonjezeka pakapita nthawi.

Tangoganizirani, mukumva kupweteka kosalekeza komwe kumatsika mwendo wanu, limodzi ndi dzanzi. Sikutha ngakhale mutamwa mankhwala. Mungaganize kuti ndi chimfine chabe. Koma kungakhale kupweteka komwe kumachitika chifukwa cha Schwannomatosis.

Kuwonjezera pa ululu, zizindikiro zina zingachitike kutengera komwe chotupa chili. Mwachitsanzo:

• Kumva ngati kugwedezeka ndi magetsi kapena kumva ngati kugwedezeka ndi magetsi .
• Kufooka kwa minofu kapena kuchepa kwa ntchito ya minofu.
• Ziphuphu kapena kutupa pansi pa khungu (kumene zotupazo zapangika) zimatha kumveka m'dzanja.

Ngakhale kuti zizindikirozi nthawi zambiri zimayamba munthu atatha zaka 20 ndipo asanakwanitse zaka 40 , kafukufuku akusonyeza kuti zimatha kuonekera pa msinkhu uliwonse.

Kodi n’chiyani chimayambitsa matenda a Schwannomatosis?

Chifukwa chachikulu cha Schwannomatosis ndi kusintha kwa majini (mutation). Izi ndi zoona makamaka pa majini otchedwa NF2, SMARCB1, kapena LZTR1. Majini amenewa amapezeka pa chromosome 22 .

Majini amenewa amagwira ntchito ngati 'oletsa chotupa', omwe amalamulira kupangika kwa zotupa m'thupi lathu. Izi zikutanthauza kuti majini amenewa amalamulira kangati maselo ayenera kukula ndikugawikana. Chifukwa chake, ngati pali 'kusintha' mu jini ya 'oletsa chotupa' ngati iyi, maselo athu salandira malangizo omwe amafunikira kuti alamulire kukula kwa maselo. Zotsatira zake, maselo amayamba kukula ndikugawikana mwachangu kwambiri, popanda kulamulira. Umu ndi momwe 'zotupa' izi zimapangikira.

Nthawi zina matenda a Schwannomatosis sakudziwika chifukwa chake chenicheni. Izi zikutanthauza kuti vutoli likhoza kuchitika ngakhale popanda kusintha kwa majini komwe kwadziwika kale.

Kodi izi ndi zolowa m'malo mwa zamoyo? (`Kodi schwannomatosis ndi zolowa m'malo mwa zamoyo?`)

Milandu ina ya 'Schwannomatosis'Ikhoza kutengera cholowa . Mwachidule, pakati pa 15% ndi 25% ya anthu omwe ali ndi Schwannomatosis ali ndi mbiri ya banja la matendawa. Amafalikira mu autosomal dominant pattern. Mwachidule, ngati kholo lililonse lilandira kopi ya jini yomwe imanyamula kusintha kwa majini, mwanayo akhoza kukhala ndi vutoli.

Komabe, milandu yambiri ya Schwannomatosis imachitika mwachisawawa . Izi zikutanthauza kuti wina akhoza kudwala Schwannomatosis mwa kukulitsa kusintha kwa majini, ngakhale palibe m'banjamo amene wakhalapo ndi vutoli kale.

Kodi mavuto omwe angakhalepo chifukwa cha Schwannomatosis ndi ati?

Ambiri mwa matenda a schwannoma ndi matenda osakhala khansa, osavulaza (matenda otupa). Izi zikutanthauza kuti si khansa. Komabe, nthawi zambiri, matenda ena amatha kukhala khansa. Ndicho chifukwa chake madokotala akusamalanso izi.

Vuto lina lalikulu ndi ululu wosatha . Ululu wopitirirawu ukhoza kukhala ndi zotsatirapo zazikulu pa thanzi la maganizo a munthu. Zikakhala zovuta kuchita ntchito za tsiku ndi tsiku komanso akalephera kuchita zinthu zomwe akufuna, zinthu monga kuvutika maganizo ndi nkhawa zimatha kuchitika. Chifukwa chake, anthu ambiri amaona kuti n'kothandiza kulankhula ndi mlangizi wa zaumoyo wamaganizo pazochitika zotere.

Kodi Schwannomatosis imapezeka bwanji?

Dokotala adzazindikira vutoli mwa kuchita mayeso ndi mayeso . Pa nthawi yoyezetsa, dokotala adzakufunsani za zizindikiro zanu, nthawi yomwe zakhalapo, komanso ngati pali aliyense m'banja mwanu amene wakhala ndi matenda ofanana ndi anu.

Popeza zizindikiro za schwannomatosis zimafanana ndi za matenda ena ndipo zimakhala zovuta kudziwa komwe ululu ukuchokera, nthawi zina zimakhala zovuta kupeza matenda nthawi yomweyo. Komabe, chifukwa madokotala tsopano akugwiritsa ntchito njira zatsopano zodziwira matenda, n'zosavuta kuzindikira mitundu ya schwannomatosis. Mwachitsanzo, kuti mupezeke ndi schwannomatosis yokhudzana ndi SMARCB1, muyenera kukhala ndi chimodzi mwa izi:

• Payenera kukhala schwannoma imodzi, ndipo mayeso a majini pogwiritsa ntchito magazi kapena malovu ayenera kutsimikizira kuti pali kusintha kwa majini a SMARCB1.
• Payenera kukhala ma schwannoma osachepera awiri, ndipo biopsy ya chimodzi mwa zotupazo iyenera kutsimikizira kuti chili ndi kusintha kwa majini kwa SMARCB1.

Ndi mayeso ati omwe amagwiritsidwa ntchito pozindikira matenda a Schwannomatosis?

Mayeso ojambulira zithunzi monga MRI (Magnetic Resonance Imaging) angathandize dokotala wanu kupeza schwannoma. Ngati chotupa chapezeka pa mayesowa, dokotala wanu angatenge chitsanzo chaching'ono cha chotupacho kuti achiyese (biopsy).Mukhoza kuyiyitanitsa. Kenako, poyang'ana maselo pansi pa maikulosikopu, mutha kudziwa bwino mtundu wa chotupacho. Kuphatikiza apo, mayeso a magazi a majini amathanso kuzindikira ngati muli ndi kusintha kwa majini komwe kumayambitsa mtundu uliwonse.

Kodi Schwannomatosis imachiritsidwa bwanji?

Kunena zoona, pakadali pano palibe mankhwala a Schwannomatosis, kotero cholinga chachikulu cha chithandizo ndikuwongolera zizindikiro .

Dokotala wanu angapereke mankhwala osiyanasiyana kuti achepetse ululu wanu . Mankhwalawa amadalira zinthu monga komwe ululu wanu uli komanso momwe ulili woopsa.

Ngati ululu sunathetsedwe ndi mankhwala, kapena ngati ululuwo ndi waukulu kwambiri, dokotala wanu angaganizire zochotsa schwannoma mwa opaleshoni kapena kutumiza ku mayesero azachipatala . Komabe, dokotala wanu adzasankha ngati izi ndi njira zotetezeka kwa inu. Opaleshoni ikhoza kuwononga mitsempha, ndipo pali mwayi woti zotupa zingamerenso mutachotsa.

Kodi zizindikiro za matenda a Schwannomatosis ndi ziti?

Izi zimasiyana kwambiri kuchokera kwa munthu ndi munthu . Zimatengera kukula, kuchuluka, ndi malo a schwannomas m'thupi lanu. Anthu ena akhoza kukhala ndi ochepa okha, pomwe ena akhoza kukhala ndi ambiri. Akhoza kukhala pamalo amodzi okha pathupi, kapena akhoza kufalikira m'malo ambiri. Chifukwa chake zizindikiro sizifanana kwa aliyense.

Chizindikiro chovuta kwambiri cha Schwannomatosis ndi ululu wosatha . Kukhala ndi ululu, makamaka ngati ndi woopsa, kungakhale kovuta kwambiri. Ululuwu ungakhudze thanzi lanu la maganizo ndi thupi. Ngati zizindikiro za Schwannomatosis zikukupangitsani kumva kupsinjika maganizo kapena kulephera kuchita zinthu zina pa moyo wanu kapena pagulu, onetsetsani kuti mwalankhula ndi dokotala. Kulankhula ndi mlangizi wa zaumoyo wamaganizo kungathandizenso.

Pali mankhwala othandiza kuchepetsa zizindikiro. Anthu ambiri amapeza mpumulo ku zizindikiro ndi mankhwala. Ena angafunike opaleshoni kuti achotse chotupacho. Koma kumbukirani kuti pali mwayi woti chotupacho chidzakulanso chikachotsedwa.

Kodi Schwannomatosis imakhudza moyo wa munthu?

Schwannomatosis siikhudza mwachindunji nthawi yomwe munthu amakhala ndi moyo . Komabe, ululu wosatha ndi zizindikiro zina zomwe zimayambitsa zimatha kukhudza moyo wabwino. Ngati muli ndi nkhawa iliyonse pankhaniyi, ndi bwino kulankhula ndi dokotala wanu mwachindunji. Popeza vuto la aliyense ndi losiyana, iye yekha ndi amene angakupatseni chidziwitso chaposachedwa kwambiri chokhudza matenda anu.

Kodi ndiyenera kupita kwa dokotala liti?

Ululu womwe simungapeze chifukwa chake.Ngati muli ndi zizindikiro monga kufooka kwa minofu , onetsetsani kuti mwaonana ndi dokotala. Komanso, ngati mwawona chotupa chatsopano kapena chotupa chilichonse m'thupi lanu, ndikofunikira kuchiwonetsa kwa dokotala.

Ngati muli kale ndi matenda a Schwannomatosis, dziwitsani dokotala wanu ngati muwona kusintha kulikonse mu zizindikiro zanu, monga kupweteka kwambiri.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Mukapita kwa dokotala, ndi bwino kufunsa mafunso ngati awa:

• Kodi ndingachite chiyani kuti ndichepetse ululu?
• Kodi pali njira zina kupatula mankhwala ochepetsa ululu?
• Kodi ndikufunika opaleshoni?
• Kodi zotsatirapo zake ndi ziti?
• Kodi ana anga angalandire vutoli mtsogolo?

Pomaliza, zinthu zoti muzikumbukira (Uthenga Wopita Nawo Kunyumba)

Kukhala ndi ululu wosatha womwe umabwera ndi Schwannomatosis kungakhale kovuta kwambiri. Masiku ena ndi osavuta kuposa ena. Ngakhale mutakhala ndi mapulani, ululuwo ungakupangitseni kuti muwachedwetse ndikukhala panyumba kuti mupumule. Izi zingasokoneze zochita zanu zaumwini komanso zachikhalidwe. Koma musalole Schwannomatosis kulamulira moyo wanu.

Dokotala angakuthandizeni kupeza njira yabwino kwambiri yothandizira zizindikiro zanu. Ngati ululu wosatha ukukhudza thanzi lanu la maganizo, mungapindulenso ndi kuonana ndi mlangizi wa zaumoyo wamaganizo . Opaleshoni ndi mayesero azachipatala zingakhalenso njira zina. Chifukwa chake, funsani dokotala wanu zomwe zingakuthandizeni kukhala patsogolo pa zizindikiro za Schwannomatosis. Kumbukirani kuti simuli nokha, ndipo pali madokotala ndi magulu othandizira kuti akuthandizeni paulendowu.

Schwannomatosis , neurofibromatosis, kupweteka kosatha, matenda a majini, NF2, SMARCB1, LZTR1, matenda a mitsempha