Tiyeni tiphunzire za Matenda a Tangier, omwe amapezeka mwa anthu omwe ali ndi cholesterol yotsika (HDL) m'thupi.

Kodi mudamvapo za mtundu wa cholesterol wotchedwa cholesterol yabwino (HDL / high-density lipoprotein) ? Inde, inde... Lero tikambirana za matenda osowa kwambiri omwe amapezeka pamene mulingo wa cholesterol yabwinoyi m'thupi mwathu uli wochepa kwambiri. Izi zimatchedwa Matenda a Tangier . Mwina simukudziwa dzinali, koma ndikofunikira kwambiri kudziwa za izi.

Kodi matenda a Tangier ndi chiyani? Tiyeni timvetse mosavuta!

Chabwino, tiyeni tiyambe kuyambira pachiyambi. Matenda a Tangier ndi matenda osowa kwambiri omwe timalandira kuchokera kwa makolo athu, kutanthauza kuti, omwe amabadwa nawo m'majini . Anthu omwe ali ndi matendawa ali ndi cholesterol yotsika kwambiri (HDL) m'matupi awo. Kodi mukudziwa, cholesterol iyi ya HDL siitchedwa "cholesterol yabwino" pachabe. Ndi iwo omwe amathandiza kuti matupi athu akhale oyera pochotsa cholesterol yoyipa (LDL / lipoprotein yotsika kwambiri) yomwe imakonda kudziunjikira m'mitsempha yathu yamagazi, kutanthauza, m'mitsempha yathu .

Tsopano ganizirani zomwe zimachitika cholesterol yabwino (HDL) ikachepa. Cholesterol yoipa (LDL) ndi mitundu ina ya mafuta (lipids) zimayamba kukhazikika m'mitsempha yathu yamagazi mosavuta. Monga momwe dothi limakhalira mu chitoliro chamadzi. Izi zingayambitse mavuto pamtima pathu, matenda a mtima , kapenanso kubweretsa matenda monga sitiroko . Sikuti zokhazo, matendawa amatha kukhudza ziwalo zina zambiri m'thupi lathu.

Nchifukwa chiyani idatchedwa "Tangier"?

Iyi ndi nkhani yosangalatsa kwambiri. Matendawa amatchedwa "Tangier" chifukwa cha Chilumba cha Tangier , chomwe chili kutsidya kwa nyanja kuchokera ku boma la Virginia ku US. Matendawa adapezeka koyamba pakati pa anthu omwe ankakhala pachilumbachi. Komabe, sizikutanthauza kuti izi ndi zomwe zimachitika pachilumbachi chokha. Palinso anthu omwe ali ndi matendawa m'maiko ena padziko lapansi.

Kodi matenda a Tangier ndi ofala bwanji?

Ndipotu, matenda a Tangier ndi matenda osowa kwambiri . Anthu ochepa okha, pafupifupi 100, ndi omwe apezeka padziko lonse lapansi. Ndicho chifukwa chake sizikunenedwa zambiri. Koma ngakhale kuti ndi osowa, ndikofunikira kudziwa za matendawa, eti?

Kodi Matenda a Tangier amakhudza bwanji thupi lathu?

Izi ndi zomwe zimachitika. Tikakhala ndi matenda a shuga, kuchuluka kwa cholesterol (HDL) m'thupi lathu kumakhala kochepa, kotero mafuta (lipids) sanganyamulidwe bwino kupita ku chiwindi chathu. Chiwindi ndi chomwe chimachotsa mafuta osafunikira awa m'thupi. Chifukwa chake, mafuta awa omwe sangachotsedwe pang'onopang'ono amayamba kusonkhana m'malo osiyanasiyana a thupi lathu. Mafuta awa akasonkhana, chiwalo chimenecho chikhozanso kukula pang'ono.

Mafuta nthawi zambiri amaikidwa motere:

• Chiwindi: Chiwindi chingakule.
• Nkhumba:Nkhumba imathanso kutupa ndikukula.
• Ma Tonsil: Ma tonsil omwe ali pakhosi pathu. Amatha kukhala achikasu ndi lalanje akadzaza ndi mafuta.
• Ma lymph nodes: Izi ndi mbali ya chitetezo chathu chamthupi. Zingathenso kutupa.
• Mtima: Izi zingakhudzenso momwe mtima umagwirira ntchito.
• Ubongo: Nthawi zina ubongo ungakhudzidwenso.

Kuwonjezera pa izi, mavuto ena angabuke:

• Mavuto a mitsempha: Mavuto a mitsempha, monga dzanzi m'miyendo, angachitike.
• Kuchuluka kwa triglycerides m'magazi: Uwu ndi mtundu wa mafuta omwe amapezeka m'magazi, monga cholesterol.
• Mavuto a maso: Pakhoza kukhala mitambo yosazolowereka m'maso, ndipo nthawi zina masomphenya angachepe.

Kodi zizindikiro za matenda a Tangier ndi ziti?

Izi ndizofunikira kwambiri. Zizindikiro za matenda a Tangier zimatha kusiyana malinga ndi munthu. Zimatengera komwe mafuta amaikidwa m'thupi, monga ndanenera kale. Anthu ena angasonyeze zizindikiro akangobadwa, pomwe ena sangasonyeze zizindikiro zazikulu mpaka atakwanitsa zaka 60-65.

Nazi zizindikiro zina zodziwika bwino:

• Kupweteka m'mimba kapena nseru.
• Mafuta m'mitsempha yamagazi (atherosclerosis): Izi zimawonjezera chiopsezo cha matenda a mtima.
• Khungu louma.
• Kuzungulira mkati mwa chikope (Ectropion): Ichi ndi chizindikiro chachilendo pang'ono.
• Kuchepa kwa magazi m'thupi: Izi zikutanthauza kusowa kwa magazi.
• Kufooka kwa minofu m'manja, miyendo, manja, kapena mapazi.
• Kutupa kwa ma lymph nodes kwa nthawi yayitali popanda matenda aliwonse.

Kumbukirani, nthawi zina zizindikirozi zingasokonezedwe ndi matenda ena, ndichifukwa chake ndikofunikira kupeza matenda olondola.

Kodi n’chiyani chimayambitsa matenda a Tangier? Tiyeni tikambirane za majini!

Matenda a Tangier amayamba chifukwa cha vuto la jini lotchedwa ABCA1 lomwe timalandira kuchokera kwa makolo athu. Mwachidule, jini la ABCA1 lili ndi malangizo ochotsera cholesterol m'maselo athu ndikuwonjezera ku cholesterol yabwino (HDL). HDL imanyamula cholesterol iyi kupita ku chiwindi, komwe imatulutsidwa.

Tsopano, ngati pali cholakwika kapena kusintha kwa majini a ABCA1, malangizo amenewo sagwira ntchito bwino. Kenako kuchotsa cholesterol m'maselo ndi kupangidwa kwa HDL sikuchitika bwino. Zotsatira zake n'zakuti milingo ya HDL imatsika kwambiri.

Umu ndi momwe zimakhalira cholowa:

• Ngati makolo onse awiri alandira jini lolakwika la ABCA1, mwanayo adzakhala ndi matenda a Tangier.
• Ngati kholo limodzi lokha ndilo lilandira jini yolakwika, mwanayo adzakhala ndi kachilomboka. Sangasonyeze zizindikiro, koma kuchuluka kwa HDL m'magazi awo kungakhale kotsika kuposa masiku onse.

Tsopano taganizirani kuti makolo onse awiri ndi omwe ali ndi jini yolakwika iyi, zomwe zikutanthauza kuti mwina sangakhale ndi zizindikiro, koma onse awiri ali ndi jiniyo. Makolo otere akakhala ndi mwana:

• Pali mwayi wa 25% (1/4) kuti mwanayo adzadwala matenda a Tangier.
• Pali mwayi wa 50% (1/2) kuti mwanayo akhale ndi matendawa.
• Pali mwayi wa 25% (1/4) kuti mwanayo sadzalandira majini aliwonse olakwika ndipo adzakhala wathanzi.

Izi zili ngati kuponya ndalama ndikupeza mitu kapena michira. Mwayi umenewu ndi wofanana pa mimba iliyonse.

Kodi madokotala amazindikira bwanji matenda a Tangier?

Kuti mudziwe ngati muli ndi matenda a Tangier, muyenera kuonana ndi dokotala. Choyamba adzakuyezani thupi lanu ndikufunsani za zizindikiro zanu. Kenako, adzayitanitsa mayeso angapo a magazi . Mayeso a magazi amenewa makamaka amayang'ana kuchuluka kwa cholesterol yanu ya HDL komanso kuchuluka kwa puloteni yotchedwa apolipoprotein A1 (ApoA1) yotsika. Zonsezi ndi zochepa kwambiri kwa anthu omwe ali ndi matenda a Tangier.

Kuyezetsa majini kungachitikenso kuti kutsimikizire matendawa. Kungayang'ane kusintha kwina kwa majini a ABCA1. Komabe, kuyezetsa majini sikungapezeke kulikonse. Pazochitika zotere, dokotala wanu angatenge chidutswa chaching'ono cha minofu (biopsy) kuchokera ku gawo la thupi lanu, monga tonsil, khungu, kapena chiwindi. Mtundu wa mafuta omwe ali m'minofu iyi ungagwiritsidwe ntchito kuti mudziwe matendawa.

Ndi mapuloteni ati omwe ali ndi vuto la matenda a Tangier?

Mu matenda a Tangier, puloteni yotchedwa apolipoprotein A1 (ApoA1) imachepa kwambiri. ApoA1 iyi ndi gawo lalikulu la molekyulu ya cholesterol ya HDL. Chifukwa chake ApoA1 ikachepa, milingo ya HDL imachepanso.

Ndi mayeso ati omwe amagwiritsidwa ntchito pozindikira matenda ndi kutsatira?

Madokotala angachitenso mayeso ena angapo kuti adziwe matendawa ndikuwunika momwe matendawa akukhudzira thupi.

• Mayeso a mitsempha ndi minofu (Electromyograms / EMGs): Yang'anani ngati mitsempha yawonongeka komanso ngati minofu yafooka.
• Kuyezetsa maso: Yang'anani ngati muli ndi vuto lililonse la maso kapena vuto la maso.
• Ultrasound pa mimba/m'mimba mwanu: Yang'anani momwe ziwalo monga chiwindi ndi ndulu zilili.
• Ultrasound pa mitsempha yanu ya carotid: Yang'anani ngati mafuta ali m'mitsempha yayikulu ya m'khosi mwanu.
• CT angiogram ya mtima wanu:Yang'anani ngati mitsempha yamagazi yatsekeka ndipo magazi akupita kumtima.
• Echocardiogram: Kujambula kuti muwone momwe mtima umagwirira ntchito komanso kapangidwe kake.
• Mayeso a kupsinjika maganizo: Onani momwe mtima umayankhira kuchita masewera olimbitsa thupi.

Kodi matenda a Tangier amachiritsidwa bwanji?

Kunena zoona, palibe mankhwala enieni omwe angachiritse matenda a Tangier kwathunthu. Popeza ndi matenda obadwa nawo, pali zinthu zambiri zomwe mungachite kuti muchepetse zizindikiro ndikuchepetsa mavuto.

Nthawi zina, chiwalo chomwe chawonongeka ndi mafuta osungidwa, mwachitsanzo ma tonsils kapena ndulu, chingafunike kuchotsedwa opaleshoni .

Kodi chakudya ndi zakumwa zingathandize?

Inde, n'zothekadi. Pali zakudya zina zomwe zingathandize kukweza pang'ono kuchuluka kwa cholesterol yabwino (HDL), komanso kuchepetsa kuchuluka kwa cholesterol yoipa (LDL).

• Ma Avokado
• Mafuta a azitona
• Nyemba monga nyemba ndi nsawawa (Nyemba)
• Mbewu zonse (monga ufa wonse, mpunga wonse)
• Nsomba zonenepa ( monga salimoni, mackerel, herring)
• Mtedza ( monga mtedza, amondi, ma cashew - koma wopanda mchere)
• Zipatso zomwe zili ndi ulusi wambiri (monga guava, mango, nthochi)
• Mbewu za Chia ndi mbewu za fulakesi

Kuyesa kuphatikiza zakudya izi muzakudya zanu nthawi zonse kudzakuthandizani kukhala ndi cholesterol yabwino.

Kodi mankhwala ndi kusintha kwa moyo ndi chiyani?

Dokotala wanu angakupatseni mankhwala ochepetsa cholesterol , monga ma statins.

Imalimbikitsanso kusintha moyo wanu kangapo komwe kungathandize kuwonjezera kuchuluka kwa HDL:

• Kuchita masewera olimbitsa thupi pafupipafupi: Izi zikuphatikizapo kuyenda kapena kuthamanga kwa mphindi zosachepera 30 patsiku.
• Kusagwiritsa ntchito fodya: Muyenera kusiya kusuta fodya kotheratu.
• Kukhalabe ndi kulemera koyenera.
• Idyani mafuta osakhuta m'malo mwa mafuta osakhuta: Mafuta osakhuta amapezeka m'mafuta monga mafuta a kokonati, mafuta a kanjedza, ndi mafuta a nyama. Mafuta osakhuta amapezeka m'mafuta a azitona ndi ma avocado.

Kodi zotsatirapo zake ndi ziti?

Mankhwala ochepetsa mafuta m'thupi nthawi zina angayambitse zotsatirapo zazing'ono. Si aliyense amene amawalandira, koma ndibwino kuwadziwa.

• Mutu
• Kupweteka kwa minofu
• Kudzimbidwa
• Mimba yopweteka

Ngati izi zitachitika, muyenera kuuza dokotala wanu. Kenako akhoza kusintha mankhwala kapena kukupatsani malangizo ena.

Kodi Matenda a Tangier angapewedwe?

Popeza ichi ndi vuto la majini, sitingathe kuliletsa kukula kwake. Izi zikutanthauza kuti ngati muli ndi vuto ili m'majini anu, silingasinthidwe. Komabe, ngati muli ndi matendawa, kapena ngati ndinu amene ali ndi matendawa, mutha kufunsa uphungu wa majini kuti mudziwe chiopsezo cha ana anu kutenga matendawa. Kenako, poganizira momwe majini a kholo lina alili, mutha kudziwa bwino mwayi womwe ana anu angatenge matendawa.

Ngati ndili ndi matenda a Tangier, n’chiyani chidzachitike mtsogolomu?

Nthawi zambiri zizindikiro za matenda a Tangier zimakhala zabwino, koma zimatengera momwe zizindikiro zanu zakulira. Monga matenda ena aliwonse, kuzindikira msanga ndi bwino, zizindikiro zisanayambe kukulirakulira.

Ngakhale kuti palibe mankhwala enieni a izi pakadali pano, pali chiyembekezo chakuti zinthu monga chithandizo cha majini zithandiza mtsogolo. Kafukufuku akupitirirabe.

Kodi matenda a Tangier amatenga nthawi yayitali bwanji?

Popeza iyi ndi matenda obadwa nawo, ndi matenda a moyo wonse. Komabe, ngati atapezeka msanga ndikuwunikidwa nthawi zonse, matendawa amatha kuthandizidwa bwino komanso kukhala nawo.

Kodi ndimadzisamalira bwanji?

Ngati muli ndi ndulu yokulira chifukwa cha matenda a Tangier, muyenera kupewa masewera olimbitsa thupi, chifukwa kukhudzana koteroko kungayambitse ndulu kuphulika, zomwe ndi zoopsa.

Kuphatikiza apo, zinthu zina zomwe zimayambitsa matenda a mtima ziyeneranso kulamulidwa:

• Kulamulira kuthamanga kwa magazi .
• Ngati muli ndi matenda a shuga , samalani bwino.
• Kupewa kugwiritsa ntchito zinthu zopangidwa ndi fodya.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati muli ndi matenda a Tangier, muyenera kupita kwa dokotala nthawi zonse . Mwanjira imeneyi, ngati zizindikiro zanu zikukulirakulira, mutha kuchitapo kanthu mwachangu.

Dokotala nthawi zambiri amafufuza zinthu izi:

• Mitsempha.
• Mtima.
• Maso.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Mukapita kwa dokotala, mungafunse mafunso monga awa:

• Kodi ndiyenera kumwa mankhwala kuti ndiwonjezere cholesterol yanga?
• Kodi pali gulu lothandizira lomwe anthu omwe ali ndi matenda a Tangier angalowe nawo?
• Kodi ndiyenera kubwera kudzakuonani kangati?

Popeza matenda a Tangier amatha kukhudza ziwalo zosiyanasiyana za thupi, ndi bwino kupita kukayezetsa ziwalo zonse nthawi zonse. Mungafunike kuonana ndi akatswiri osiyanasiyana. Imwani mankhwala monga momwe dokotala wanu wanenera, ndipo yesetsani kukhala ndi zakudya zabwino komanso kuchita masewera olimbitsa thupi.

Zinthu zofunika kwambiri zomwe tiyenera kukumbukira (Uthenga Wopita Nawo Kunyumba)

Chabwino, ndiloleni ndifotokoze mwachidule zina mwa zinthu zomwe muyenera kukumbukira kuchokera pa zomwe takambirana.

• Matenda a Tangier ndi matenda osowa, obadwa nawo omwe amachititsa kuchepa kwakukulu kwa cholesterol yabwino (HDL).
• Izi zingayambitse cholesterol yoipa (LDL) ndi mafuta kudziunjikira m'thupi ndikukhudza ziwalo monga chiwindi, ndulu, matoni, ndi mtima.
• Zizindikiro zimasiyana, ndipo anthu ena akhoza kukhala ndi mavuto a mitsempha, mavuto a khungu, komanso mavuto a maso.
• Izi zimachitika chifukwa cha vuto la jini la ABCA1 .
• Matendawa amapezeka kudzera mu mayeso a magazi, mayeso a majini, ndipo nthawi zina mayeso a minofu (biopsy) .
• Ngakhale kuti palibe mankhwala enieni, zizindikiro zimatha kuthetsedwa ndi zakudya, kusintha moyo, mankhwala, ndi opaleshoni zina.
• Kuzindikira msanga ndi kulandira chithandizo chamankhwala pafupipafupi ndikofunikira kwambiri.

Kotero, ndikukhulupirira kuti izi zikuthandizani. Ngati muli ndi mafunso ena okhudza izi, musazengereze kulankhula ndi dokotala. Khalani ndi thanzi labwino!

Matenda a Tangier, cholesterol ya HDL, cholesterol ya LDL, matenda a majini, kasamalidwe ka cholesterol, chiopsezo cha matenda a mtima, ApoA1