Kodi mankhwala a cholesterol (statins) amabweretsa zotsatirapo zoyipa kwa inu? Tiyeni tikambirane za 'Statin Intolerance'!

Kodi dokotala wanu wakupatsani mankhwala ochepetsa cholesterol yanu? Mwina mukumwa. Awa amatchedwa ma statins. Amatiteteza ku matenda akuluakulu monga matenda a mtima ndi sitiroko. Koma nthawi zina mankhwala awa angayambitse kusasangalala, makamaka kupweteka kwa minofu. Ngati ndi choncho, nkhaniyi idzakhala yofunika kwambiri kwa inu. Lero tikambirana za vuto lomwe anthu ambiri ali nalo, lomwe limatchedwa 'kusalolera kwa statin'.

Choyamba, tiyeni tiwone, kodi ma statins ndi chiyani? Chifukwa chiyani amagwiritsidwa ntchito?

Mwachidule, ma statin ndi gulu la mankhwala omwe madokotala amapereka kuti achepetse kuchuluka kwa cholesterol "yoyipa" m'chiwindi ndi m'magazi mwathu. Mwina munamvapo mayina awa: Atorvastatin, Rosuvastatin, Simvastatin ndi ena mwa ma statin omwe amagwiritsidwa ntchito kwambiri ku Sri Lanka.

Tsopano tiyeni timvetse pang'ono za cholesterol. Tangoganizani kuti tili ndi mitundu iwiri ya cholesterol m'thupi lathu. Chimodzi chili ngati bwenzi labwino , ndipo china chili ngati mdani woipa .

• Cholesterol yabwino (HDL): Tikakhala ndi mafuta ambiri m'thupi lathu, zimakhala bwino chifukwa amatiteteza ku matenda monga matenda a mtima ndi sitiroko.
• Cholesterol yoipa (LDL): Awa ndi adani athu. Akachuluka m'magazi, amaikidwa m'mitsempha yathu yamagazi, kuitseka ndikuwonjezera chiopsezo cha matenda a mtima ndi sitiroko.

Mankhwala a statin amagwira ntchito pochepetsa kuchuluka kwa cholesterol yoyipa (LDL). Chifukwa chake, mankhwalawa amathandiza anthu omwe ali pachiwopsezo cha matenda a mtima kukhala ndi moyo wathanzi komanso wautali.

Ndiye, kodi 'kusalolera kwa statin' ndi chiyani?

Kusalolera mankhwala a statin ndi pamene zotsatira zoyipa za mankhwala a statin zimaposa zabwino zake. Izi zikutanthauza kuti thupi lanu silingathe "kulekerera" mankhwalawo. Izi zitha kukhala ziwengo kapena zotsatira zina zoyipa.

Izi zikachitika, simungathenso kugwiritsa ntchito mankhwalawa kuti muchepetse cholesterol yanu. Nthawi zambiri, chizindikiro chachikulu ndi kupweteka kwa minofu, kufooka, kapena kufooka .

Zizindikiro zodziwika bwino za 'Statin Intolerance'

Ngati mwayamba kugwiritsa ntchito ma statins, yang'anirani zizindikiro izi.

Kodi ndi zinthu ziti zomwe zimayambitsa 'kusalolera kwa statin'?

Anthu ena ali ndi mwayi waukulu wopeza vutoli. Tiyeni tigawane zinthu zoopsazi m'magulu awiri. Zina sitingathe kuzisintha, koma zina tikhoza kuzithetsa.

Kodi dokotala amazindikira bwanji vutoli molondola?

Mukapita kwa dokotala wanu, iye adzakufunsani kaye za zizindikiro zanu, mankhwala ena aliwonse omwe mukumwa, komanso mbiri ya banja lanu yachipatala. Kenako, angachite mayeso ena kuti adziwe ngati ma statins akukuyambitsani zizindikiro kapena ngati pali vuto lina lachipatala.

• Kuyezetsa magazi: Izi zimathandiza kuchotsa ma enzyme a chiwindi, ma enzyme a minofu (Creatine Kinase), ndi matenda ena.
• Kuyesa minofu: Kufufuza ngati minofu yafooka.
• Mayeso ena: Mayeso a majini kapena biopsy ya minofu angalimbikitsidwe, koma nthawi zambiri izi zimachitika kawirikawiri.

Ngati muli ndi vuto la 'kusalolera kwa statin', kodi njira zothetsera mavuto ndi ziti?

Tangoganizani kuti dokotala watsimikiza kuti muli ndi vutoli. Musadandaule. Pali njira zingapo zothetsera vutoli.

1. Kusintha mlingo wa mankhwala anu: Dokotala wanu angachepetse mlingo wa mankhwala anu a statin, kapena kusiya kumwa mankhwalawo kwa kanthawi kuti aone ngati zizindikiro zanu zikuchepa. Nthawi zina, angakusinthireni ku mtundu wina wa statin.

2. Mankhwala ena osakhala a statin: Ngati ma statin sangagwiritsidwe ntchito, pali mitundu ina ya mankhwala ochepetsa cholesterol.

• Mankhwala oletsa ACL: Izi zimachepetsa kupanga cholesterol yoyipa (LDL) ndi chiwindi.
• Zoletsa za PCSK9: Izi zimaletsa puloteni yapadera m'thupi lathu ndipo zimathandiza kuchotsa cholesterol yoipa (LDL) m'thupi.
• Fibrates: Izi zimathandiza kuchepetsa cholesterol yoyipa (LDL) komanso kuwonjezera cholesterol yabwino (HDL).
• Ma Bile acid sequestrants: Izi zimaletsa kuyamwanso kwa cholesterol m'magazi.

3. Kusintha kwa moyo: Izi ndizofunikira kwambiri. Ndi mankhwala kapena popanda mankhwala, zinthuzi zingathandize kuchepetsa kuchuluka kwa cholesterol m'thupi lanu.

• Zakudya zabwino: Idyani mafuta ochepa, shuga, ndi mchere, komanso idyani ndiwo zamasamba, zipatso, ndi zitsamba zambiri.
• Kuchita masewera olimbitsa thupi: Kuchita zinthu monga kuyenda kapena kusambira tsiku lililonse.
• Kusiya zizolowezi zoipa: kusiya kusuta fodya ndi kumwa mowa.

4. Zakudya Zowonjezera: Nthawi zina, dokotala wanu angakulangizeni kumwa zakudya zowonjezera monga vitamini D kapena Coenzyme Q10 (CoQ10) kuti muchepetse kupweteka kwa minofu. Komabe, ndikofunikira kufunsa dokotala wanu musanayambe izi.