Dziwani zambiri za chithandizo cha Xolair cha rhinosinusitis yosatha yokhala ndi ma polyps a m'mphuno

Mphuno yanu nthawi zonse imakhala yotsekeka, zimakhala zovuta kupuma, simunganunkhize kapena kulawa chilichonse, mphuno yanu imatuluka madzi nthawi zonse... Kodi mwakhala mukuvutika ndi zizindikirozi kwa nthawi yayitali? Mwina chifukwa cha izi ndi rhinosinusitis yosatha, yomwe ndi kutupa kwa nthawi yayitali kwa sinuses komwe kumabwera ndi zotupa zazing'ono (mphuno) zomwe zimamera mkati mwa mphuno yanu. Ngakhale anthu ambiri amatha kuwongolera izi ndi mankhwala opopera m'mphuno ndi mapiritsi, anthu ena samachira mokwanira mosasamala kanthu kuti atenga nthawi yayitali bwanji chithandizochi. Lero, tikambirana za chithandizo chatsopano chomwe chingathandize anthu otere, ndipo chimagwira ntchito mosiyana. Ichi ndi chithandizo cha jakisoni chotchedwa Xolair.

Choyamba, tiyeni tiwone kuti sinusitis yokhala ndi ma polyps a m'mphuno ndi chiyani?

Mwachidule, mabowo odzaza mpweya omwe ali m'chigaza chozungulira mphuno yathu amatchedwa sinuses. Matenda a rhinosinusitis osatha ndi pamene sinuses ndi mkati mwa mphuno zimatupa ndi kutupa kwa nthawi yayitali, zomwe zimatha miyezi yoposa itatu. Pamene kutupa uku kukupitirira, tinthu tating'onoting'ono, tofewa ( polyps ) tomwe timaoneka ngati mphesa timayamba kumera kuchokera m'malo ena a mkati mwa mphuno.

Nthawi zambiri, ma polyp amenewa sayambitsa zizindikiro zilizonse. Koma nthawi zina amakula ndikuyamba kutseka njira za mphuno ndi m'mphuno. Pamenepo ndi pomwe mavuto amayamba.

• Mphuno yotsekeka : Mphuno imatsekeka nthawi zonse.
• Mphuno yotuluka madzi: Kutuluka madzi pafupipafupi m'mphuno.
• Kusowa fungo ndi kukoma : Simungamve fungo la kukoma kwa chakudya kapena fungo la duwa.
• Kupweteka kwa sinus : Ngati mamina sangathe kutuluka m'maenje a sinus, amatha kudziunjikira, zomwe zimayambitsa ululu ndi kupanikizika. Nthawi zina, izi zimatha kutenga kachilomboka .

Chofunika kwambiri pochiza vutoli ndikuchepetsa kutupa m'mphuno ndi m'mphuno. Kenako ma polyps adzachepa ndipo zizindikiro ziyamba kuchepa.

Kodi katemera wa Xolair amagwira ntchito bwanji?

Mankhwala otchedwa Xolair ali ndi chogwiritsira ntchito cha omalizumab. Ntchito yake ndi yapadera kwambiri. Amalimbana mwachindunji ndi gawo la chitetezo cha mthupi lathu.

Taganizirani thupi lathu ngati linga. Pamene chinthu choyambitsa matenda a allergen chilowa m'lingaliro limeneli, "alonda" a thupi lathu nthawi yomweyo amayamba kugwira ntchito ndikuyamba kulimbana nalo. Limodzi mwa "alonda" amenewa ndi puloteni yotchedwa Immunoglobulin E (IgE) . Kwa anthu omwe ali ndi vutoli, chitetezo ichi, chotchedwa IgE, chimagwira ntchito mopitirira muyeso. Chimachita zinthu mopitirira muyeso ngakhale zazing'ono kwambiri, zomwe zimapangitsa kutupa ndi kutupa kosafunikira mkati mwa mphuno.

Zimene katemera wa Xolair amachita ndikuletsa ntchito ya puloteni ya IgE yogwira ntchito mopitirira muyeso. Zili ngati kutonthoza mlonda wodandaula. Pamene IgE yasiya kugwira ntchito, vuto la ziwengo ndi kutupa, kufiira, ndi ntchofu zomwe zimayambitsa zimawongoleredwa. Izi zimapangitsa kuti ma polyps a m'mphuno achepe ndipo zizindikiro zimayamba kusintha.

Kodi chithandizochi n'choyenera kwa ndani?

Si aliyense amene ali ndi vutoli amene amapatsidwa Xolair nthawi imodzi. Nthawi zambiri chithandizo chimachitika pang'onopang'ono.

Kodi mankhwalawa ndi othandizadi?

Inde. Mayeso awiri akuluakulu azachipatala, POLYP 1 ndi POLYP 2, achitika kuti atsimikizire kugwira ntchito kwa mankhwalawa. Onse omwe adachita nawo mayesowa anali anthu omwe amagwiritsa ntchito mankhwala opopera mphuno tsiku lililonse koma adakumanabe ndi zizindikiro.

Zotsatira zake zinasonyeza kuti anthu omwe adalandira katemera wa Xolair anali ndi kuchepa kwakukulu kwa chiwerengero cha ma polyps a m'mphuno . Zizindikiro zawo zotsekeka m'mphuno nazonso zinachepa kwambiri.

Kodi Xolair imagwiritsidwa ntchito bwanji? Ndipo idzachira mofulumira bwanji?

Xolair ndi jakisoni wamadzimadzi. Amabayidwa pansi pa khungu . Nthawi zambiri amaperekedwa milungu iwiri kapena inayi iliyonse . Dokotala wanu adzadziwa kuchuluka kwa mankhwala omwe mukufuna komanso kuchuluka kwa mankhwala omwe mukufuna.

• Mlingo woyamba: Mudzapatsidwa mlingo woyamba wa mankhwala awa motsogozedwa ndi dokotala kuchipatala kapena kuchipatala. Izi ndi zowunikira ngati pali vuto lililonse la ziwengo lomwe lingachitike mwa anthu ena.
• Kenako kunyumba: Ngati mulibe vuto, ndi chilolezo cha dokotala wanu, mutha kuphunzitsidwa kudzipatsa katemerayu kunyumba. Pali chipangizo chosavuta kugwiritsa ntchito, chodzazidwa kale chotchedwa ``autoinjector'' cha izi.
• Zotsatira: Nthawi zambiri muwona kusintha pang'ono kwa zizindikiro zanu mkati mwa mwezi woyamba kuyambira mutayamba kulandira chithandizo. Zizindikiro zitha kupitirirabe kusintha m'miyezi ingapo ikubwerayi.

Tiyeni tiphunzire za zotsatirapo zake komanso chitetezo chake.

Monga mankhwala ena onse, pali mwayi woti pakhale zotsatirapo zake. Komabe, zotsatirapo zake zoyipa zimakhala zochepa kwambiri.

Chofunika kwambiri n'chakuti anthu ena amakhala ndi vuto lalikulu la ziwengo (anaphylaxis) atatha kumwa mankhwala oyamba.Izi zingayambitse kuvutika kupuma mwadzidzidzi, kutupa, komanso chizungulire. Izi ndi zadzidzidzi.

Ndicho chifukwa chake nthawi zonse mumalandira mlingo wanu woyamba kuchipatala kapena kuchipatala chifukwa cha chiopsezo chimenecho. Kenako, ngati pali vuto, pali ogwira ntchito zachipatala ophunzitsidwa bwino kuti alichiritse. Choncho simuyenera kuda nkhawa nalo.

Kupatula izi, zotsatirapo zazing'ono monga kufiira, kuyabwa, ndi ululu zimatha kuchitika pamalo omwe jakisoniyo adayikidwa. Ngati muwona zizindikiro zachilendo, dziwitsani dokotala wanu nthawi yomweyo.