Chiyembekezo chatsopano kwa iwo omwe ali ndi Myasthenia Gravis (MG): Tiyeni tiphunzire za mankhwala a Zilbrysq (Zilucoplan)!

Kodi muli ndi vuto lotchedwa Myasthenia Gravis (MG)? Ndiye mwina mukudziwa bwino momwe kufooka kwa minofu, zikope zopindika, kuvutika kulankhula, ndi kumeza kungavutitsire moyo wanu. Muyenera kugwiritsa ntchito mankhwala osiyanasiyana kuti muchepetse vutoli. Koma chinthu chimodzi chomwe mungasangalale nacho ndichakuti posachedwapa, mankhwala atsopano ayambitsidwa kuti athetse matendawa. Lero, tikambirana za Zilbrysq, jakisoni watsopano womwe ungagwiritsidwe ntchito kunyumba.

Choyamba, tiyeni tiwone chomwe Myasthenia Gravis (MG) ili.

Mwachidule, Myasthenia Gravis (MG) ndi matenda omwe amabwera chifukwa cha chitetezo chamthupi. Izi zikutanthauza kuti chitetezo chamthupi lathu, kapena chitetezo chamthupi, chimayamba molakwika kuukira maselo athu athanzi.

Tangoganizani kuti ubongo wathu watumiza uthenga ku minofu kuti 'ugwire'. Uthengawu umayenda motsatira mitsempha. Malo omwe mitsempha ndi minofu zimalumikizana ali ngati 'cholumikizirana'. Timatcha izi kuti cholumikizirana cha mitsempha. Pa cholumikizirana ichi, pali 'ma receptor' apadera omwe amalandira uthenga wa mitsempha. Mu MG, chitetezo chathu chamthupi chimaukira ma receptor awa otchedwa 'acetylcholine receptors'. Kenako uthenga wochokera ku ubongo sulandiridwa bwino ndi minofu. Zotsatira zake, minofu imatopa mwachangu kwambiri ndipo imakhala yofooka.

Si aliyense amene ali ndi MG amene amakumana ndi zizindikiro zomwezo. Anthu ena amayamba mwadzidzidzi zizindikiro , pomwe ena amawonjezeka pang'onopang'ono pakapita nthawi. Nthawi zina pamakhala nthawi zina zomwe zizindikiro zimatha.

Kodi mankhwala a Zilbrysq amagwira ntchito bwanji?

Cholinga chachikulu chochiza MG ndikubwezeretsa mauthenga a mitsempha kudzera mu acetylcholine receptor. Mankhwala monga pyridostigmine (Mestinon), ma steroids monga prednisone, ndi ma immunosuppressants amagwiritsidwa ntchito kwambiri pochita izi.

Zilbrysq ndi mankhwala atsopano omwe amagwira ntchito mosiyana. Timatcha mankhwalawa kuti 'oletsa mankhwala owonjezera'.

Mukukumbukira pamene ndinanena kuti chitetezo chathu chamthupi chimaukira minofu yathu? Pali chinthu chotchedwa "njira yothandizira" chomwe chimagwira ntchito yofunika kwambiri panjira yowukira iyi. Zimene Zilbrysq amachita ndikuletsa ntchito ya dongosolo lothandizirali. Kenako chitetezo chamthupi chimachepetsa kuukira koopsa pa ma receptor. Zotsatira zake, mauthenga a mitsempha amayamba kupita ku minofu moyenera, ndipo mphamvu ya minofu imakulanso.

Kodi Zilbrysq ingagwiritsidwe ntchito ndi aliyense amene ali ndi MG?

Ayi, si aliyense amene angathe. Mankhwalawa amavomerezedwa kwa anthu okhawo omwe ali ndi antibody inayake yotchedwa ``anti-acetylcholine receptor antibody'' m'magazi mwawo. Anthu ambiri omwe ali ndi MG (pafupifupi 80%-90%) ali ndi antibody iyi. Koma ngati mulibe iyi m'magazi mwanu, mankhwalawa sangakhale othandiza kwambiri. Chifukwa chake, musanayambe kumwa mankhwalawa, dokotala wanu adzakuyesani magazi mwapadera kuti awone ngati muli ndi antibody iyi.

Kodi mumagwiritsa ntchito bwanji mankhwalawa?

Zilbrysq ndi mankhwala amadzimadzi omwe amabayidwa pansi pa khungu tsiku lililonse. Akhoza kubayidwa m'ntchafu, m'mimba, kapena kumbuyo kwa mkono wapamwamba.

• Kusungira: Mankhwalawa ayenera kusungidwa mufiriji.
• Musanagwiritse ntchito: Chotsani katemera mufiriji kwa mphindi 30-45 musanamupatse jakisoni ndipo mulole kuti afike kutentha kwa chipinda. Izi zichepetsa ululu mukalandira jakisoni.
• Maphunziro: Mukayamba kulandira mankhwala awa, dokotala wanu kapena namwino adzakuwonetsani momwe mungawagwiritsire ntchito jakisoni molondola. Ndikofunikira kwambiri kuwagwiritsa ntchito monga momwe mwalangizidwira kuti mupeze mlingo woyenera. Ngati pali chilichonse chomwe simukutsimikiza, funsani dokotala wanu kachiwiri.

Zinthu zapadera zomwe muyenera kudziwa musanayambe kumwa mankhwala

Iyi ndi gawo lofunika kwambiri, choncho samalani kwambiri.

Mankhwalawa angawonjezere chiopsezo cha matenda ena akuluakulu, makamaka matenda a meningococcal. Chifukwa cha chiopsezochi, mankhwalawa amapezeka kokha kudzera mu pulogalamu yapadera yotetezera yotchedwa pulogalamu ya Zilbrysq REMS. Inu ndi dokotala wanu muyenera kulembetsa mu pulogalamuyi.

Monga gawo la pulogalamuyi, dokotala wanu adzakuphunzitsani za matenda a meningococcal, momwe mungawapewere, momwe mungazindikire zizindikiro, komanso kufunika kofuna upangiri wa dokotala nthawi yomweyo ngati zizindikiro zayamba.

• Katemera: Kuti achepetse chiopsezo chotenga matenda, dokotala wanu adzaonetsetsa kuti mwalandira katemera wa meningococcal milungu iwiri musanayambe Zilbrysq. Ngati mukufuna kuyamba kumwa mankhwala mwachangu ndipo simunalandire katemera, muyenera kumwa maantibayotiki mpaka katemerayo atayamba kugwira ntchito.
• Khadi Loteteza: Mudzapatsidwa 'Khadi Loteteza Wodwala' lapadera. Muyenera kusunga khadi ili nthawi zonse. Ndikofunikira kulisunga pamene mukumwa mankhwala, komanso kwa miyezi iwiri mutasiya kumwa mankhwala. Mutha kuwonetsa khadi ili kwa dokotala wina aliyense amene akukuthandizani.

Zotsatirapo zake ndi momwe mungathanirane nazo?

Monga mankhwala ena aliwonse, Zilbrysq ingayambitse zotsatira zina zoyipa, koma zambiri mwa izo zimatha kuthandizidwa.

Kodi ndingayembekezere zotsatira nthawi yayitali bwanji?

Ngati Zilbrysq ndi yoyenera kwa inu, mungaone kusintha pang'ono kwa zizindikiro zanu mkati mwa sabata yoyamba mutayamba kumwa mankhwala. Anthu ambiri amaona zotsatira zabwino mkati mwa mwezi woyamba.

Ngati simukuwona kusintha kulikonse mu zizindikiro zanu mutamwa mankhwala kwa mwezi umodzi kapena iwiri, lankhulani ndi dokotala wanu. Iye adzakulangizani za njira zina zochiritsira.