Ese platelets zawe ziri hejuru? Reka tuvuge kuri Thrombocytosis!

Ese nawe warafashwe n'indwara yo kugabanya amaraso mu maraso yawe? Cyangwa hari umuntu uzi ufite iyi ndwara? Ni ibisanzwe kumva ufite ubwoba gato iyo wumvise ikintu nk'iki. Ariko ntugahangayike, uyu munsi turaganira kuri iyi ndwara yitwa Thrombocytosis mu buryo bworoshye ushobora kumva.

Thrombocytosis ni iki? Mu magambo make…

Mu magambo make, thrombocytosis ni igihe ufite platelets nyinshi mu maraso yawe. Noneho ushobora kuba wibaza uti “platelets ni iki?” Icyo ni ikibazo cy'ingenzi cyane!

Platelets ni ubwoko bw'uturemangingo duto tuboneka mu maraso yacu. Inshingano yatwo nyamukuru ni uguhagarika kuva amaraso iyo habayeho kuva amaraso, urugero nk'igihe habaye igikomere. Bikora nk'umuyoboro muto w'amaraso.

Ariko se bigenda bite iyo umubare wa platelets wiyongereye cyane? Amaraso yawe ashobora kuba menshi kandi agafatana. Mu bihe bimwe na bimwe bikomeye, izi platelets zirenze urugero zishobora gutuma amaraso afungana mu miyoboro y'amaraso. Ibi bishobora kongera ibyago byo kurwara indwara nko gucika imitsi cyangwa indwara z'umutima .

Ariko, si ko indwara zose za Thrombocytosis ziba zifite akaga gakomeye. Uburemere bw'iyi ndwara, niba ukeneye kuvurwa cyangwa utakeneye kuvurwa, biterwa n'impamvu.

Hari ubwoko bubiri bw'ingenzi bwa thrombocytosis:

Yego, abaganga bagaragaje ubwoko bubiri bw'ingenzi bw'iyi ndwara. Reka tubiganireho gato.

1. Thrombocythemia y'ingenzi (ET) cyangwa Thrombocytosis y'ibanze

Iyi ni indwara idakunze kubaho mu maraso. Ibaho iyo umwongo wo mu magufwa yawe - uruganda rw'uturemangingo tw'amaraso ruri mu magufwa yawe - rukora platelets nyinshi cyane. Tekereza nawe, inyinshi mu turemangingo tw'amaraso mu mibiri yacu zikorerwa muri uyu mwongo wo mu magufwa. Umuntu ufite thrombocythemia y'ingenzi agira umusaruro mwinshi udasanzwe wa platelets bitewe n'inenge iri muri uyu mushinga wo gukora uturemangingo tw'amaraso.

Iyi ndwara, yitwa ET (Essential Thrombocythemia) , ifatwa nk'indwara ikunze kugaragara cyane mu itsinda ry'amaraso yitwa Myeloproliferative Neoplasm (MPN) .

2. Thrombocytosis ikora neza cyangwa Thrombocytosis ya kabiri

Ubu ni bwo bwoko bwa Thrombocytosis bukunze kugaragara cyane. Iki ni cyo gihe umubiri wawe ukora platelets nyinshi bitewe n'indi ndwara, ubwandu, imvune, kubagwa, cyangwa gukuraho urwagashya. Mu magambo make, umubiri wawe ugira icyo ukora ku kindi kintu kandi wongera urugero rwa platelets. Ibi ni byo bituma umubiri wawe ukora platelets nyinshi.Indwara yo kugabanya amaraso mu maraso ikunze kuba iy'igihe gito, bivuze ko iyo impamvu yabyo imaze gukemuka, umubare w'udupira tw'amaraso usubira ku rugero rusanzwe.

Ni nde urwara thrombocytosis?

Iyi ndwara ikunze kugaragara cyane ku bantu barengeje imyaka 60. Nanone, bivugwa ko ubwoko bwitwa Essential Thrombocythemia (ET) bugaragara ku bagore inshuro ebyiri kurusha abagabo.

Ni izihe mpamvu zitera thrombocytosis?

Impamvu z'ubwo bwoko bubiri twavuze mbere nazo ziratandukanye.

Impamvu zitera indwara ya Essential Thrombocythemia (ET)

Indwara ya Essential Thrombocythemia (ET) ni indwara iterwa n’uturemangingo. Si ikintu uvukana. Iterwa n’impinduka, cyangwa impinduka, mu turemangingo tumwe na tumwe tugira uruhare mu ikorwa rya platelets. Ibi bituma umwongo w’amagufwa yawe ukora platelets nyinshi cyane.

Abantu barenga kimwe cya kabiri barwaye Essential Thrombocythemia (ET) bafite impinduka muri JAK2 gene. Impinduka muri CALR cyangwa MPL gene nazo zirakunze kugaragara.

Abahanga mu bya siyansi ntibarabasha kumenya neza impamvu zitera iyi mihindagurikire y’uturemangingo, ariko ubushakashatsi kuri byo burakomeje.

Impamvu za Thrombocytosis ikora neza

Ubu bwoko bw'ibi bibaho bitewe nuko umubiri wawe ukora platelets nyinshi bitewe n'indwara zitandukanye. Cyangwa, rimwe na rimwe, bishobora no guterwa nuko platelets zishaje zirundanya aho kwangirika ku muvuduko usanzwe.

Dore bimwe mu bintu bishobora gutera uburwayi bwa thrombocytosis buterwa n'imikorere y'umubiri :

• Anemia , cyane cyane anemia yo kubura icyuma .
• Izindi ndwara z'amaraso.
• Amoko amwe na amwe ya kanseri .
• Indwara zandurira mu maraso, nk'umusonga .
• Indwara zo kubyimba - indwara zitera kubyimba mu mubiri, nka rubagimpande.
• Imvune .
• Kunanirwa kw'impyiko .
• Imiti imwe n'imwe.
• Kubagwa, cyane cyane kubagwa mu nda.
• Gukuraho imikaya.
• Kuvura ibura rya Vitamine B12 .

Uru rutonde rurimo impamvu nke zisanzwe. Hari izindi mpamvu nyinshi zishobora gutera uburwayi bwa Thrombocytosis .

Ni ibihe bimenyetso bya thrombocytosis?

Akenshi, abantu bafite umubare munini wa platelet ntibagira ibimenyetso, nibura mu ntangiriro. Niba ufite Reactive Thrombocytosis , ushobora kugira ibimenyetso by'uburwayi bwayiteye.

Ariko, iyo ibimenyetso bigaragaye, akenshi bifitanye isano no kuva amaraso ku buryo budasanzwe no kugabanya amaraso mu mubiri wawe. Ushobora kubona ibimenyetso nka:

• Umutwe .
• Gukomereka byoroshye.
• Kumva ufite intege nke, uzungera cyangwa ufite isereri.
• Kuva amaraso mu mazuru, mu kanwa no mu ishinya.
• Kuva amaraso mu gifu cyangwa mu mara.

Bamwe mu bantu barwaye Essential Thrombocythemia (ET) bashobora kurwara indwara yitwa Erythromelalgia . Ibi bitera ububabare, kubyimba no gutukura mu biganza no mu birenge. Bashobora kandi kugira ibinya no kuribwa mu biganza no mu birenge.

Mu bihe bikomeye, thrombocytosis ishobora gutera kubyimba kw'amaraso mu nda (urugero: Budd-Chari syndrome ) no kongera ibyago byo kurwara indwara zo mu bwonko cyangwa indwara z'umutima .

Ni gute indwara ya thrombocytosis ipimwa?

Kubera ko thrombocytosis akenshi idatera ibimenyetso, ikintu cya mbere ubona ni uko isuzuma ry’amaraso risanzwe (urugero: Complete Blood Count – CBC ) rigaragaza ko umubare w’amaraso mu maraso wiyongera.

Thrombocytosis isobanurwa ko ifite platelets zirenga 450.000 kuri mikorolitiro imwe y'amaraso. Niba umubare wa platelets zawe uri hejuru, muganga wawe ashobora gusaba ko habaho ikindi gipimo cy'amaraso mu byumweru bike kugira ngo arebe niba urugero rukomeje kuba hejuru. Kongera inshuro imwe umubare wa platelets hanyuma ugasubira ku buzima busanzwe ntabwo akenshi biba ikibazo. Ariko, urugero rwo hejuru ruhoraho rushobora kugaragaza ikibazo cy'uburwayi.

Mu gihe cy’indwara ya thrombocytosis iterwa n’imisemburo , kumenya indwara yateye iyi ndwara (urugero: kubura amaraso mu byuma , kanseri, ubwandu) bishobora gufasha abaganga kuyisuzuma no kuyivura. Ariko, niba muganga atabonye impamvu nk’iyo, bazakora ibindi bipimo kugira ngo barebe niba ufite Essential Thrombocythemia (ET) .

Ibi bizamini bishobora kuba birimo:

• Gupima amaraso yo mu mpande:Ibi bireba niba platelets mu maraso yawe zisa n'izidasanzwe.
• Ibipimo bya ADN/genetic: Ibi bishobora kugaragaza impinduka mu ikoranabuhanga nka JAK2 , zikunze kujyana na ET (Essential Thrombocythemia) .
• Kugenzura uturemangingo tw’amagufwa: Ibi bireba uturemangingo tw’amagufwa yawe kugira ngo turebe ko nta turemangingo tudasanzwe dufite.

Indwara yo kugabanya amaraso mu maraso ivurwa ite?

Niba nta bimenyetso ufite, ushobora gukenera gusa kwisuzumisha buri gihe.

Indwara yo kuvura indwara ya thrombocytosis (iy’itsinda rya kabiri) akenshi ntikenera kuvurwa. Ubusanzwe, urugero rwa platelets rusubira ku murongo iyo indwara yateye umubare munini wa platelets (nk'imvune, ubwandu, cyangwa ingaruka zo kubagwa) imaze gukemuka. Ariko, niba ufite ibimenyetso, muganga wawe azavura impamvu nyamukuru.

Niba ufite Essential Thrombocythemia (ET) kandi ukaba ufite ibimenyetso, muganga wawe ashobora kukugira inama yo kuvura indwara zitandukanye, nko:

• Gufata aspirine yo ku rugero ruto buri munsi: Ushobora gufata aspirine buri munsi kugira ngo wirinde kubyimba kw'amaraso. Iyi doze yo ku rugero ruto ubusanzwe ntitera kubabara mu gifu cyangwa kuva amaraso. Ariko, ntugafate aspirine buri gihe utabanje kuvugana na muganga.
• Gufata imiti igabanya urugero rwa platelets: Imiti nka Hydroxyurea (amazina y’ibirango: Droxia®, Hydrea®, Siklos®, Mylocel®) na Anagrelide (izina ry’ikirango: Agrilyn®) bigabanya ikorwa rya platelets mu musokoro w’amagufwa. Interferon alfa (izina ry’ikirango: Multiferon®) ibuza platelets zidasanzwe kwigabanya no kwiyongera.
• Kugira uburyo bwo gukuraho platelets zawe: Niba urugero rwa platelets zawe ruri hejuru cyane ku buryo ushobora kugira ibyago byo kurwara amaraso ashobora kugabanya ubuzima, muganga wawe ashobora kukugira inama yo gukoresha uburyo bwitwa platelets . Ibi bikubiyemo gukoresha imashini kugira ngo uvane platelets zirenze mu maraso yawe. Ariko, mu bihe byinshi bya thrombocytosis , platelets ntiziba ari ngombwa.

Icy'ingenzi: Ntugatangire cyangwa ngo uhagarike ubwo buryo bwose bwo kuvura utabanje kugisha inama muganga. Byose bigomba kuganirwaho na muganga wawe kandi bigakorwa hakurikijwe ubuyobozi bwe.

Ese thrombocytosis ishobora gukira burundu?

Thrombocythemia y'ingenzi (ET)Kugeza ubu nta muti uhari wo kuvura indwara ya thrombocytopenia. Ariko, muganga wawe ashobora kugufasha guhangana n’iyi ndwara kugira ngo agabanye ibyago byo kubyimba kw’amaraso. Mu gihe cy’indwara ya thrombocytose iterwa n’impamvu za kabiri, urugero rwa platelets rusubira kumera neza iyo impamvu nyamukuru imaze kuvurwa.

Ese thrombocytosis ishobora kwirindwa?

Indwara nyinshi zitera thrombocytosis ntizishobora kwirindwa, harimo na Essential Thrombocythemia (ET) .

Ese thrombocytosis itera ubuzima mu kaga?

Kugabanuka kw'imitsi yo mu maraso (platelets) mu maraso ntabwo bibangamira ubuzima, ariko ingorane zishobora kubaho - nko kubyimba kw'amaraso cyangwa kuva amaraso menshi - zishobora kuba akaga.

Impamvu nyinshi zitera thrombocytosis ni iz'igihe gito, kandi ntizikunze gutuma amaraso acika cyane. Muri Essential Thrombocythemia (ET) , ibyago biba byinshi kurushaho. Ariko, muganga wawe azagukurikiranira hafi, akwandikire imiti ikenewe, kandi akore ibikorwa bikenewe kugira ngo wirinde ko amaraso acika intege. Rero ntugahangayike.

Ni iki cyizere cy’umuntu ufite thrombocytosis?

Ubusanzwe indwara yo kuvura amaraso iterwa n’amaraso irakira iyo ikibazo cyayo kivuwe. Nubwo umubare w’amaraso akoreshwa mu maraso yawe ushobora kwiyongera igihe gito (ndetse bikaba byanabaho igihe kirekire nyuma yo gukurwaho urwagashya), indwara yo kuvura amaraso mu maraso ya kabiri ntabwo itera kubyimba kw’amaraso kudasanzwe.

Essential Thrombocythemia (ET) , cyangwa thrombocytosis y’ibanze, ishobora gutera kuva amaraso cyane cyangwa ibibazo byo kuvura amaraso. Gufata imiti kugira ngo urugero rw’imitsi yawe ikomeze kuba nk’uko bisanzwe bishobora gufasha kwirinda ibi. Ariko, nyuma y’imyaka myinshi ufite iyi ndwara, fibrosis y’umusemburo w’amagufwa (ibisebe mu musemburo w’amagufwa) ishobora kubaho. Umubare muto w’abantu bafite Essential Thrombocythemia (ET) nabo bashobora kurwara leukemia .

Ni ryari ngomba kubonana na muganga wanjye?

Kurikiza amabwiriza ya muganga wawe neza ku nshuro ugomba kujya kwisuzumisha kwa muganga ndetse no kumenya niba ugomba gupimwa amaraso kugira ngo urebe umubare w'udukoko twa platelet mu maraso yawe.

Ni ryari nkwiye kujya mu ishami rishinzwe ubutabazi bwihutirwa (ETU) ?

Niba ubonye ibimenyetso by'indwara yo mu bwonko cyangwa indwara y'umutima, hamagara 1990 ako kanya cyangwa ujye mu cyumba cy'ubutabazi bw'ibanze cy'ibitaro biri hafi yawe. Menya neza ibi bimenyetso.

Ni ibihe bibazo ngomba kubaza muganga wanjye?

Ushobora kubaza muganga wawe ibibazo nk'ibi:

• Ese nkwiye guhangayikishwa n'urugero rw'imitsi yanjye yo mu bwoko bwa platelet ruri hejuru?
• Ese nkeneye gukorerwa ibizamini byinshi kugira ngo nongere ndebe urugero rw'imitsi yanjye yo mu bwoko bwa platelet?
• Ni ibihe bizamini nzakenera gukora kugira ngo menye icyateye Thrombocytosis yanjye?
• Ni ubuhe buryo bwo kuvura usaba?
• Ni izihe mpinduka nakora mu mibereho yanjye kugira ngo menye uko nakira iyi ndwara?

Niba ibisubizo by'ibipimo by'amaraso yawe bigaragaza ko platelets zawe ziri hejuru, ntugatinye. platelets zawe zishobora kuba nyinshi bitewe n'impamvu zitandukanye. Impamvu nyinshi muri izi ntizisaba kuvurwa. Ariko niba urugero rwawe ruhora ruri hejuru kandi ufite ibimenyetso, muganga wawe azagerageza gushaka impamvu. Gukurikirana witonze no gufata imiti bishobora gukumira ingorane zikomeye zijyanye na thrombocytosis.

Amaherezo, ibintu byo kwibuka (Ubutumwa bwo kujyana mu rugo)

Uyu munsi twaganiriye cyane kuri Thrombocytosis, si byo se? Ndizera ko ubisobanukiwe neza.

Igikuru ni ukudatinya niba usanze urugero rw'imitsi yawe iri hejuru. Si indwara zose za Thrombocytosis zishobora guteza akaga.

• Ubwoko bwa thrombocytosis iterwa n'imiti ni bwo bukunze kugaragara cyane, kandi akenshi iterwa n'indi mpamvu y'igihe gito. Ibi bizagenda neza iyo iyo ndwara imaze kuvurwa.
• Indwara ya Essential Thrombocythemia (ET) ni indwara idakunze kugaragara ishobora gusaba ubuvuzi bw'igihe kirekire.
• Menya neza ko ugiye gupimwa no kuvurwa bikwiye nk'uko muganga wawe yabigutegetse.
• Ntukirengagize ibimenyetso. Shaka ubufasha bwihuse kwa muganga, cyane cyane niba uva amaraso adasanzwe, ufite ibisebe, uribwa umutwe cyane, ubabara mu gituza, cyangwa uhumeka nabi.
• Vugana na muganga wawe nta guhisha . Baza ikibazo cyangwa impungenge ufite.

Wibuke ko utari wenyine. Uramutse uhawe ubuyobozi n'ubufasha bukwiye n'abaganga, ushobora kwihanganira iki kibazo neza kandi ukabaho ubuzima bwiza.