Reka twige ku ikizamini cya ACTH Stimulation Test mu buryo bworoshye.

Ese ukunze kumva unaniwe, unaniwe, cyangwa ugabanya ibiro? Iyo ugiye kwa muganga, ashobora gufata icyemezo cyo gusuzuma imisemburo yawe. Cyane cyane, imisemburo ya cortisol. Rero, ikizamini nyamukuru gikorwa kugira ngo harebwe niba urugero rwa cortisol yawe ari rusanzwe ni ACTH Stimulation Test. Nubwo izina rishobora kumvikana nk'aho rigoye, mu by'ukuri ni ikintu cyoroshye cyane. Reka tubiganireho uyu munsi.

Mu magambo make, iki kizamini cyo gukangura ACTH ni iki?

Iki ni ikizamini cy’ubuvuzi. Mu by’ukuri, kirareba uburyo ingingo zawe ebyiri zitwa glande z’impyiko zikira imisemburo yitwa ACTH (Adrenocorticotropic hormone) iva mu bwonko bwacu. Ese ibi bisa nkaho bitera urujijo? Reka tubitekerezeho muri ubu buryo.

Tekereza ko agahu k'ubwonko ka pituitari kari mu bwonko bwawe kameze nk'umuyobozi w'ikigo kinini. Utunyangingo tubiri duto tw'inkende turi hejuru y'impyiko zawe tumeze nk'abakozi babiri bakora muri icyo kigo.

Iyo umuyobozi (gland pituitary) ashaka gukora ikintu runaka, yohereza ubutumwa bwitwa 'ACTH' ku bakozi (gland adrenal). Iyo ubu butumwa bwakiriwe, abakozi (gland adrenal) bakora imisemburo yitwa 'cortisol' bakayirekura mu mubiri. Iyi cortisol ni imisemburo y'ingenzi cyane ku mubiri wacu. Ifasha mu bintu byinshi nko kugenzura imihangayiko, kugenzura urugero rw'isukari mu maraso, no kugenzura umuvuduko w'amaraso.

Rero, icyo ACTH Stimulation Test ikora ni uko dushyira mu mubiri wawe imisemburo ya ACTH ikorwa hanze (yitwa cosyntropin) maze tukareba niba imisemburo yawe y’intanga ngabo (abakozi) bayikira neza kandi igakora cortisol neza.

Iki kizamini gikoreshwa cyane cyane mu gusuzuma indwara yitwa 'insufficiency adrenal' . Ibi bivuze ko ingirabuzimafatizo z'intanga zikora cortisol ihagije. Ibi bigabanyijemo ubwoko butatu.

Ni mu bihe bidasanzwe muganga akubwira gukora iki kizamini?

Hari impamvu nyinshi zishobora gutuma muganga wawe agusaba iki kizamini.

• Niba ikizamini cy’amaraso cyakozwe mbere cyagaragaje ko urugero rwa cortisol ruri hasi: Niba warigeze gupimwa amaraso ku mpamvu yindi yagaragaje ko urugero rwa cortisol ruri hasi, ushobora gusabwa gukora iki kizamini kugira ngo wemeze ko ari cyo.
• Niba ufite ibimenyetso byo kunanirwa k'ubuhumekero bw'impyiko: Nkuko twabivuze mbere, niba ufite ibimenyetso nko kunanirwa guhoraho, kugabanya ibiro, kubabara mu gifu, isesemi, isereri, n'umuvuduko w'amaraso uri hasi, iki kizamini gikorwa kugira ngo hamenyekane niba iyi ndwara ari yo itera.
• Niba umaze igihe kinini ufata imiti ya steroid: Iyo ukoresheje imiti ya glucocorticoid nka prednisone igihe kirekire, imyakura yawe ya pituitary na adrenal glands ishobora guhagarika gukora by'agateganyo. Rero, nyuma yo guhagarika gufata imiti, iki kizamini gikorwa kugira ngo harebwe niba imyakura yongeye gukora neza.

Wakwitegura ute mbere yo gukora ikizamini?

Ibi ni ingenzi cyane. Ugomba gukurikiza amabwiriza ya muganga wawe neza. Ubusanzwe, ushobora kuvuga ibintu nk'ibi.

• Kwiyiriza ubusa: Ushobora gusabwa kutarya cyangwa kunywa ikintu icyo ari cyo cyose mu masaha agera kuri 6 mbere yo kwipimisha. Amazi gusa ni yo yemewe.
• Ibibujijwe mu bikorwa: Ushobora gusabwa kwirinda ibikorwa nk'imyitozo ngororamubiri igoye amasaha 12-24 mbere yo gukora ikizamini.
• Ibiryo: Hari igihe ushobora gusabwa kurya ibiryo birimo karubohidrati nyinshi.
• Guhagarika imiti: Imiti imwe n'imwe ufata (cyane cyane amavuta ya steroid, ibinini, cyangwa imiti ihumeka) ishobora kugira ingaruka ku bisubizo by'ibizamini. Kubwibyo, muganga wawe ashobora kugusaba guhagarika kuyifata by'agateganyo. Ntugahagarike gufata imiti yawe utabanje kubibaza muganga.

Noneho reka turebe uko bizagenda ku munsi w'ikizamini.

Ibi ntabwo biteye ubwoba nkuko ushobora kubitekereza. Akenshi bikorerwa mu bitaro cyangwa kwa muganga w’indwara z’imitsi. Dore uko bigenda intambwe ku yindi.

1. Gufata amaraso ya mbere: Ubwa mbere, umuforomo azafata amaraso mu mutsi uri mu kuboko kwawe. Ibi bizasuzuma urugero rwa cortisol yawe mbere yuko ikizamini gitangira.

2. Gutera urushinge: Hanyuma, umuforomo azaguha urushinge rurimo ACTH (cosyntropin) ya sintetike. Ubusanzwe urushinge rushyirwa mu mitsi y'ukuboko kwawe. Ruzumva nk'aho ari agakoko gato kakuruma, ariko kazashira mu masegonda make.

3. Ingero z'amaraso za kabiri n'iza gatatu: Uzongera guterwa andi maraso nyuma y'iminota 30 nyuma yo guterwa inshinge. Hanyuma undi maraso azaterwa nyuma y'iminota 60. Ibi bizapima ingano ya cortisol adrenal glands yawe imaze gukora kuva watewe inshinge.

4. Kohereza muri laboratwari: Ingero z'amaraso yafashwe zoherezwa muri laboratwari.

Iyo ufashwe amaraso, wumva urimo gukubitwa gato gusa. Ibyo bishira nyuma y'igihe runaka. Ushobora kumva agasebe gato aho amaraso yakuwe, ibi bikaba ari ibisanzwe.

Ni ryari ibisubizo bizaboneka kandi bizavuga iki?

Bishobora gufata icyumweru kimwe kugira ngo ibisubizo by'iki kizamini bigaruke. Ibi biterwa nuko iyo ibisubizo byabonetse, muganga wawe azabyigaho witonze kandi abigereranye n'ibimenyetso byawe kugira ngo agere ku mwanzuro.

Igisubizo gisanzwe ni iki?

Ku muntu muzima, nyuma yo guterwa inshinge za ACTH, imisemburo y’inkende igomba kuba ishyushye neza kandi urugero rwa cortisol mu maraso rugomba kwiyongera cyane. Muganga wawe azagusobanurira agaciro kari muri raporo ya laboratwari yawe n'urugero rusanzwe.

Igisubizo kidasanzwe ni iki?

• Kunanirwa kw'intanga ngabo z'impyiko (niba hari ikibazo ku ngirabuzimafatizo z'impyiko): Ku muntu ufite iyi ndwara, nubwo yaterwa inshinge za ACTH, urugero rwa cortisol ntirwiyongera na gato cyangwa ngo rwiyongereho gato cyane. Ibi biterwa nuko ikibazo kiri mu ngirabuzimafatizo z'impyiko z'impyiko, kandi uko byagenda kose, ntizishobora gukora cortisol.
• Kunanirwa kwa kabiri kw'intanga ngore (niba hari ikibazo kuri pituitary gland): Iyo pituitary gland idatanze ACTH igihe kirekire, intanga ngore zigenda zigabanuka buhoro buhoro zigatangira kudakora (atrophy). Iyo umuntu nk'uwo ahawe inshinge za ACTH, intanga ngore zitagira icyo zikora ntizishobora guhita zikora. Kubwibyo, urugero rwa cortisol yazo ruriyongera gato cyane cyangwa ntirwiyongere na gato.

Hari igihe, iyo ikibazo cya pituitary gland kibaye gishya cyane cyangwa kikaba cyarangiritseho igice, urugero rwa cortisol rushobora kwiyongera gato. Muganga wawe ni we muntu mwiza wo gufata icyemezo kuri ibi byose.