Ese koko uzi iby'iyi hormone "iteye isoni" yitwa Adiponectin?

Twese twumvise ubwoko butandukanye bw'imisemburo mu mibiri yacu. Tuvuga kuri imwe muri yo igihe cyose, ndetse n'abaganga barayivugaho. Ariko se wigeze wumva imisemburo yitwa Adiponectin ? Wenda ntabwo warigeze uyimenya. Ariko igira uruhare runini mu mibiri yacu, cyane cyane mu bintu nk'ibiro byacu n'urugero rw'isukari mu maraso. None rero, uyu munsi, reka tuganire kuri Adiponectin mu buryo bworoshye kandi butaziguye.

Adiponectin ni iki? Biroroshye cyane!

Muri make, adiponectin ni imisemburo ya poroteyine ikorwa ahanini n'uturemangingo tw'ibinure, cyangwa ingirangingo z'amafuta, mu mibiri yacu. Nanone yitwa adipokine , kuko ikorwa hamwe n'ibinure. Ariko, ntabwo ikorwa n'uturemangingo tw'ibinure gusa, ahubwo no mu bindi bice by'umubiri wacu.

Uyu mugabo witwa Adiponectin yavumbuwe mu myaka ya 1990. Bivuze ko abahanga mu bya siyansi bacyiga byinshi kuri yo. Birashoboka ko hari ibindi bintu iyi hormone ikora tutaramenya kugeza ubu. Nkuko twabibonye, ​​ahanini bifasha kongera ubushobozi bw'umubiri wacu bwo kumva insuline no kugabanya ububyimbirwe mu mubiri .

Ni izihe nyungu za Adiponectin ku mubiri wacu?

Iyi nshuti yitwa Adiponectin igira uruhare mu bikorwa byinshi by'ingenzi mu mubiri wacu. Reka turebere hamwe bibiri by'ingenzi cyane.

1. Uburyo bwo gukangurira umubiri wacu kumva insuline

Uzi icyo insuline ari cyo? Mu magambo make, insuline ni nk'urufunguzo rufungura urugi rwo kwemerera isukari (glucose) kwinjira mu turemangingo tw'umubiri wacu. Kuba umuntu yumva insuline neza bivuze ko uru rufunguzo rushobora gufungura urugi neza. Hanyuma umubiri ushobora gukoresha isukari byoroshye no kugumana urugero rw'isukari mu maraso ku rugero rukwiye.

Rero, uku ni ko Adiponectin ifasha:

• Imitsi yawe y'amagufwa n'umwijima bifasha umubiri wawe kwakira insuline neza.
• Yongera irekurwa rya insuline iva muri pancreas.
• Bihagarika ububiko bw'isukari butari ngombwa bwitwa glycogen mu mwijima.
• Bifasha gusenya aside irike no gukora ingufu.

Tekereza nawe, uturemangingo tw'umubiri wawe tumeze nk'amazu. Insulini ni yo itwara ibiryo byitwa isukari muri ayo mazu. Adiponectin ifasha kuzana ibiryo mu muryango. Hanyuma inzu ikabona ibiryo, si byo se?

2. Uburyo bwo kugabanya ububyimbirwe mu mubiri

Kubyimba ni igihe ubudahangarwa bw'umubiri wacu bwohereza uturemangingo kugira ngo turwanye ikintu nk'udukoko cyangwa ngo dukize igikomere. Hari igihe ibi biba ngombwa. Ariko kubyimba guhoraho, Ibyo bivuze ko atari byiza ko umubiri uhora ufite ububyimbirwe buto imbere. Tekereza ko uhora ufite ubushyuhe buto mu mubiri wawe... Uko ni ko ububyimbirwe budakira bwitwa.

Adiponectin ifasha kugabanya ububyimbirwe mu bice bikurikira:

• Macrophages (ubwoko bw'uturemangingo tw'amaraso twera twica ibintu nka bagiteri na virusi)
• Uturemangingo tw’imbere mu mutima (utu ni uturemangingo dukora uturemangingo duto dushyira imbere mu mutima no mu miyoboro y’amaraso)
• Uturemangingo tw'imitsi
• Uturemangingo tw’imbere mu mubiri (utu ni uturemangingo dutwikira ubuso bwose bw’umubiri imbere n’inyuma yawo)

Mu kugabanya ububyimbirwe muri ubu buryo, Adiponectin irinda izi ngingo:

• Uturemangingo tw'imitsi
• Umutima
• Ibihaha
• Utubyimba duto

Ni hehe Adiponectin ikorerwa mu mubiri wacu?

Adiponectin ikorwa kandi igasohorwa ahanini n'uturemangingo twitwa adipocytes, tubika ingufu mu turemangingo tw'amafuta yera . Uturemangingo tw'amafuta yera ni ubwoko bw'ibinure mu mibiri yacu. Biboneka muri:

• Ibinure biri munsi y'uruhu - ni ukuvuga urwego rw'ibinure twumva iyo tubikozeho.
• Ibinure byo mu nda - Ibi ni ibinure biri mu nda bishobora guteza akaga gato.
• Umworo w'amagufwa (ibinure by'umuyoboro w'amagufwa)

Adiponectin ishobora kandi gukorwa n'izindi selile:

• Uturemangingo tw'imitsi y'amagufwa
• Uturemangingo tw'imitsi y'umutima
• Uturemangingo tw'imbere mu nda

Ni gute urugero rwa adiponectin rugenzurwa?

Nkuko nabivuze mbere, adiponectin ni ikintu gishya cyavumbuwe. Bityo abahanga mu bya siyansi baracyayikoraho ubushakashatsi. Kugeza ubu, habonetse imisemburo myinshi ifasha mu kugena urugero rwa adiponectin.

Nubwo imisemburo ya insuline isa nkaho igira uruhare muri ibi, si bose bemeranya ku buryo nyabwo bibaho.

Insulini-like growth factor (IGF-1) na GH (growth hormone) bigenzura irekurwa rya adiponectin mu nyama y'ibinure. Leptin (indi hormone ikorwa n'uturemangingo tw'ibinure) na yo ishobora kuba irimo.

Ni gute wasuzuma urugero rwa Adiponectin?

Ushobora gusuzuma urugero rwa Adiponectin yawe ukoresheje isuzuma ry'amaraso .

Hari igihe abaganga bitiranya diyabete yo mu bwoko bwa 2 n'indwara ya metabolike.Ikizamini cy'amaraso cya adiponectin gishobora gukoreshwa mu gufasha gusuzuma indwara nka:

Ese urugero rusanzwe rwa adiponectin rukwiye kuba rumeze rute?

Ingano isanzwe ya adiponectin iratandukanye bitewe n'igitsina cyawe ndetse n'igipimo cy'uburemere bw'umubiri (BMI) , ari na byo biremereye ukurikije uburebure bwawe.

Ubwoko busanzwe bwa Adiponectin ku bagabo ni ubu bukurikira:

• Iyo BMI iri munsi ya 25: mikorogarama 5 kugeza kuri 37 kuri mililitiro (5 kugeza kuri 37 ug/mL)
• Niba BMI iri hagati ya 25 na 30: 5 kugeza 28 ug / mL
• Niba BMI irenze 30: 2 kugeza 20 ug / mL

Ubwoko busanzwe bwa Adiponectin ku bagore ni ubu bukurikira:

• Niba BMI iri munsi ya 25: 5 kugeza kuri 37 ug/mL
• Niba BMI iri hagati ya 25 na 30: 4 kugeza 20 ug/mL
• Niba BMI irenze 30: 4 kugeza 22 ug / mL

Icy'ingenzi ni uko iyi mibare ishobora gutandukana gato bitewe n'umuntu ku wundi ndetse no muri laboratoire. Rero, reba ingano isanzwe kuri raporo ya laboratoire yawe. Niba ufite ikibazo ku bisubizo byawe, menya neza ko wabaza muganga wawe cyangwa umuforomo wawe.

Ni izihe ndwara zishobora kuvuka iyo urugero rwa adiponectin rudasanzwe?

Hari indwara nyinshi zagiye ziterwa n'urugero rudasanzwe rwa adiponectin. Izi zirimo:

• Umubyibuho ukabije n'ibiro bike
• Ubudahangarwa bwa insuline
• Ateriosclerosis
• Lipodystrophy

Inyinshi muri izi ndwara zifitanye isano n'urugero ruto rwa adiponectin .

Adiponectin n'umubyibuho ukabije

Abantu bafite umubyibuho ukabije baba bafite urugero ruto rwa adiponectin. Ku rundi ruhande, abantu bafite abana bato cyane, baba batewe n'indwara nka anorexia nervosa cyangwa imirire mibi, baba bafite urugero rwo hejuru rwa adiponectin.

Muri make, uko ibinure by'umubiri w'umuntu byiyongera, urugero rwa adiponectin mu mubiri we ruragabanuka. Mu buryo nk'ubwo, uko ibinure by'umubiri bigabanuka, urugero rwa adiponectin mu mubiri we ruriyongera. Iyo umuntu ubyibushye cyane agabanutse ibiro, urugero rwa adiponectin mu mubiri we ruriyongera.

Adiponectin no kurwanya insuline

Kubera ko adiponectin ifasha kongera ubushobozi bwo kumva insuline, abantu bafite ubushobozi bwo kumva insuline akenshi baba bafite urugero ruto rwa adiponectin. Ubuhanga bwo kumva insuline ni igihe uturemangingo tw'umubiri wawe tudakira insuline neza, bigatuma umubiri wawe urekura insuline nyinshi cyane (hyperinsulinemia).

Bitewe no kudakora neza kwa insulineIndwara ya diyabete mbere y’uko umuntu avuka, diyabete yo mu bwoko bwa 2 , na diyabete yo mu gihe cyo gutwita ishobora kugaragara. Ibi bikunze kujyana n’umubyibuho ukabije. Ariko, abantu badafite umubyibuho ukabije nabo bashobora kugira ubudahangarwa bwa insuline. Igitangaje ni uko abantu badafite ubudahangarwa bwa insuline batabyibushye cyane baba bafite urugero ruto rwa adiponectin. Ibi bigaragaza ko hari ikintu kigize imiterere y’umubiri kigira uruhare mu kudahangarwa kwa insuline na adiponectin.

Adiponectin na Ateriosclerosis

Atherosclerosis ni indwara aho plaque yibumbira imbere mu mitsi yawe, ikayifunga. Ni nk'ingese ziyongera mu muyoboro w'amazi.

Adiponectin ifite ubushobozi bwo kurwanya ububyimbirwe, burinda umutima n'imiyoboro y'amaraso. Rero, iyo urugero rwa adiponectin ruri hasi, ibyago byo kurwara indwara z'umutima nka atherosclerosis n'indwara z'umutima bishobora kwiyongera.

Adiponectin na Lipodystrophy

Lipodystrophy ni indwara idakunze kugaragara cyane itera gutakaza ibinure mu bice bimwe na bimwe by'umubiri n'ibinure byinshi byiyongera mu bindi.

Lipodystrophy ishobora kubaho kuva umuntu avutse, cyangwa ishobora no kugaragara mu gihe cy'imyaka myinshi. Urugero rwa Adiponectin ruri hasi mu maraso n'amafi afitanye isano na virusi itera SIDA . Ibi bishobora guterwa n'uko adiponectin igira uruhare mu buryo ibinure byo mu mubiri bibikwamo.

Ese hari uburyo bwo kuvura urugero rudasanzwe rwa adiponectin?

Mu by’ukuri, hari uburyo bwo kuvura busanzwe bushobora gufasha kongera urugero rwa adiponectin. Muri ubwo buryo harimo imyitozo ngororamubiri ihoraho no kugabanya ibiro neza. Ariko, ugomba guhora uvugana na muganga wawe mbere yo kugira impinduka zikomeye ku mirire yawe cyangwa gahunda yawe yo gukora imyitozo ngororamubiri.

Imiti ya diyabete nka metformin na thiazolidinediones yagaragaye ko yongera urugero rwa adiponectin.

Abahanga mu bya siyansi ubu barimo gukora ubushakashatsi ku miti ikora nk'uko Adiponectin ikora mu kuvura indwara zidakira zo kubyimba. Iyo ishobora kuba inkuru nziza kuri twe mu gihe cya vuba!

Ni irihe tandukaniro riri hagati ya Adiponectin na Leptin?

Leptin na Adiponectin ni imisemburo ikorwa kandi igasohorwa n'ibinure byawe, ubwoko bwa adipokines. Leptin ikora mu kongera ingufu mu mikorere y'umubiri no kugabanya ubushake bwo kurya.

Kimwe na adiponectin, urugero rudasanzwe rwa leptin narwo rufitanye isano n'umubyibuho ukabije - ariko mu buryo butandukanye. Urugero rwa leptin ruriyongera uko ibinure byo mu mubiri byiyongera. Ariko, urugero rwa adiponectin ruragabanuka uko ibinure byo mu mubiri byiyongera. Byoroshye kwibuka, si byo?

Amaherezo, ikintu cy'ingenzi kurusha ibindi

Birashoboka ko ubu usobanukiwe akamaro ka adiponectin ku mibiri yacu. Kubera ko ari ikintu gishya cyavumbuwe, abahanga mu bya siyansi baracyabyiga byinshiho.

Niba ufite ikibazo cy’imikorere y’umubiri nk’umubyibuho ukabije cyangwa diyabete yo mu bwoko bwa 2, ushobora kuba warumvise muganga wawe avuga kuri adiponectin. Niba hari icyo muganga wawe avuze ku ijambo, ntutinye kumubaza. Bari hano kugufasha.

Nta kintu na kimwe cyo guhangayikishwa n'urugero rwa adiponectin yawe. Ingeso nziza ku buzima, indyo yuzuye, no kubaho ubuzima busanzwe akenshi ni bwo buryo bwiza bwo kugenzura urugero rw'imisemburo. Rero, fata neza umubiri wawe, kuko ubuzima ari cyo kintu cy'ingenzi cyane!

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