Uburyo bwo kuvura ihungabana: Ese uzi ibinini bya 'Isocarboxazid'?

Ese rimwe na rimwe wumva ubabaye cyane, uhangayitse, cyangwa se urambiwe ubuzima? Mu buvuzi, iyi ndwara tuyita "Depression". Rero, abaganga baduha imiti imwe n'imwe kugira ngo idufashe mu bihe nk'ibi. Urugero, umuti wihariye ukoreshwa mu kuvura indwara yitwa "depression" ni "Isocarboxazid". "Marplan" ni irindi zina ry'uyu muti.

Ni ubuhe bwoko bw'umuti 'Isocarboxazid'?

Mu magambo make, 'Isocarboxazid' ni umuti ufasha kugabanya agahinda, imihangayiko no kunoza ibyiyumvo byawe. Ubwonko bwacu bugizwe n'ibintu bitera imiti byitwa 'Dopamine', 'Norepinephrine' na 'Serotonin'. Ibi ni imiti ifasha mu kugenzura ibyiyumvo byacu by'ibyishimo n'agahinda. 'Isocarboxazid' ikora mu kongera urugero rw'ibi bintu mu bwonko.

Uyu muti uri mu itsinda ry'imiti yitwa `MAOI`. `MAOI` isobanura `Monoamine Oxidase Inhibitors`. Uyu musemburo (`Monoamine Oxidase`) usenya imiti yavuzwe mbere nka `Dopamine`, `Norepinephrine`, `Serotonin` mu mubiri wacu. Rero, kubera ko umuti wa `MAOI` uhagarika imikorere y'uwo musemburo, iyo miti myiza iguma mu bwonko igihe kirekire. Ibyo nibyo bifasha kugabanya kwiheba. Ariko abaganga bashobora no kuguha uyu muti ku zindi ndwara. Niba ufite ikibazo, baza muganga wawe cyangwa umufarumasiye.

Ibintu ugomba kubwira muganga wawe mbere yo gutangira uyu muti

Mbere yo gutangira gufata 'Isocarboxazid', hari ibintu bike ugomba kubwira muganga wawe. Kubera ko uyu muti udakwiriye buri wese. Kubwibyo, ugomba kubwira muganga wawe ibi bintu mu buryo buboneye.

• Ese ufite indwara y'amaso yitwa 'Glaucoma'?
• Ese ukunze kurwara umutwe cyangwa migraine?
• Urwaye indwara y'umutima?
• Ufite umuvuduko w'amaraso ukabije?
• Ese wigeze ugira umutima utari umeze neza mbere?
• Ese wigeze ugira ikibazo cyo gucika intege mu bwonko (stroke) mbere yaho?
• Ese ukunda kunywa inzoga buri gihe?
• Urwaye impyiko?
• Urwaye umwijima?
• Ese hari izindi ndwara zo mu mutwe?
• Ese hari indwara ya kanseri mu gasabo k'intanga ngore kitwa `Pheochromocytoma`?
• Ese uherutse kugira imvune mu mutwe (ihungabana mu mutwe)?
• Ese hari indwara zo mu mutwe?
• Ese wigeze ugira ibitekerezo byo kwiyahura, imigambi cyangwa ukagerageza kwiyahura mbere? Hari umuntu wo mu muryango wawe wigeze abikora?
• Ese ufite ubwivumbure ku muti wa `Isocarboxazid`, indi miti, ibiryo, amarangi, cyangwa imiti irinda indwara?
• Uratwite cyangwa urimo gushaka gutwita?
• Ese uri umubyeyi wonsa?

Niba hari kimwe muri ibi kikureba, ni ngombwa cyane kumenyesha muganga wawe ibyacyo.

Uyu muti nkwiye kuwukoresha nte?

Uyu muti uza mu buryo bw'ibinini. Ugomba kunyobwa unywa n'ikirahure cy'amazi. Ni byiza kuwufata nk'uko muganga wawe yabigutegetse, icyarimwe buri munsi. Komeza gufata uyu muti kugeza igihe muganga wawe azakubwiriye kuwuhagarika.

Iyo farumasi iguhaye uyu muti, inaguha agapapuro k'amabwiriza yihariye (`MedGuide`). Ugomba gusoma iyi `MedGuide` witonze igihe cyose ufata umuti n'igihe uhindura icupa ry'umuti. Irimo amakuru y'ingenzi cyane kuri uyu muti.

Ibuka: Uyu muti ni uwawe gusa. Ntugasangire umuti wawe n'abandi, kabone n'iyo baba bafite ibimenyetso nk'ibyawe.

Niba uha abana bato uyu muti, ugomba kwitabwaho by’umwihariko. Kubwibyo, vugana na muganga wawe kandi ugire inama.

Niba ubona ko wafashe uyu muti urenze urugero ku bushake, jya mu bitaro bikuru bireba ubutabazi bwihuse, cyangwa uhamagare ikigo gishinzwe kurwanya uburozi, vuba na bwangu.

Wakora iki niba wabuze dose y'umuti?

Niba wibagiwe gufata dose, fata ako kanya wibuka. Ariko, niba igihe cyo gufata dose ikurikira kigeze, rekeraho dose yabuze hanyuma ufate dose ikurikira ku gihe cyagenwe. Ntukigere ufata dose ebyiri icyarimwe. Kubikora bishobora kongera dose.

Ibindi bintu bishobora kugira ingaruka kuri uyu muti (imikoranire)

Iki ni ikintu cyo kwitondera cyane . Umuti 'Isocarboxazid' ushobora kugira ingaruka mbi cyane ku biribwa bimwe na bimwe n'indi miti. Ibi bishobora guteza ingaruka mbi.

Irinde ibiryo birimo 'Tyramine'!

Si byiza kurya ibiryo birimo tyramine nyinshi mu gihe ufata `Isocarboxazid`. Iyo ibi byombi bihujwe, indwara zishobora guterwa n’ubuzima nko kuribwa umutwe cyane, umuvuduko ukabije w’amaraso (`Hypertensive crisis`), cyangwa umutima utera nabi.

Ni ibihe biribwa birimo 'Tyramine' nyinshi?

• Foromaje zishaje
• Inyama zatunganyijwe - ibintu nka sosiso, salami, pepperoni
• Inzoga n'ibinyobwa bitagira inzoga (ndetse n'inzoga zitarimo inzoga)
• Divayi (cyane cyane divayi itukura), sheri
• Inzoga zikomeye, Ibinyobwa bivanze
• Avoka
• Imineke (cyane cyane ikuze neza)
• Inzabibu, Imiti y'umuzabibu
• Isosi ya soya, isupu ya Miso
• Ibikomoka ku musemburo/poroteyine
• Tofu (Umuti w'ibishyimbo)
• Ibishishwa bya Fava cyangwa broad bean
• Imbuto iyo ari yo yose ikuze cyane

Uru rutonde ntirwuzuye, bityo saba muganga wawe, umufarumasiye, cyangwa inzobere mu by'imirire kugira ngo akubwire urutonde rwuzuye rw'ibiribwa birimo tyramine.

Nanone, ni byiza kugabanya ibinyobwa birimo kafeyine (nk'icyayi, ikawa, shokora, na cola) mu gihe ufata uyu muti.

Baza muganga wawe igihe ugomba kwirinda ibi biribwa n'ibinyobwa nyuma yo guhagarika uyu muti.

Imiti idakwiye gufatwa n'uyu muti

Imiti ikurikira ishobora gutera ingaruka zikomeye cyane iyo uyifashe hamwe na 'Isocarboxazid'. Kubwibyo, niba urimo gufata iyi miti, ugomba kubimenyesha muganga wawe.

• Atomoxetine
• 'Buspiron'
• 'Carbamazepine'
• Imiti imwe n'imwe ivura umuvuduko ukabije w'amaraso: `Guanabenz`, `Guanadrel`, `Guanethidine`, `Reserpine`
• 'Cocaine'
• 'Cyclobenzaprine'
• Dextromethorphan (irimo imiti igabanya inkorora)
• Imiti yo kugabanya ibiro cyangwa imiti itera imbaraga: Amphetamine, Ephedra
• 'Diphenoxylate'
• 'Ephedrine'
• Imiti igabanya ububabare rusange cyangwa iyo mu gace utuyemo (niba ufata iyi miti mbere yo kubagwa, ugomba kubimenyesha muganga wawe )
• Ginseng
• Icyayi cy'icyatsi kibisi (gukoresha cyane)
• `Guarana`
• Linezolid (umuti urwanya udukoko)
• Ubundi bwoko bwa `MAOI`: `Phenelzine` (phenelzine), `Rasagiline` (rasagiline), `Safinamide` (safinamide), `Selegiline` (selegiline), `Tranylcypromine` (tranylcypromine)
• Imiti ivura umutwe uterwa na migraine
• Imiti ivura indwara zo mu mutwe nka Parkinson: `Entacapone`, `Levodopa`, `Selegiline`, `Tolcapone`
• Meperidine (umuti ugabanya ububabare)
• `Ubururu bwa Methylene`
• Imiti ivura izindi ndwara zo kwiheba, guhangayika, cyangwa ihungabana
• Imiti ivura ububabare yanditswe na muganga
• `Procarbazine`
• `SAM-e`
• 'St. John's Wort' (umuti w'ibimera bamwe bafata kugira ngo bagire ubuzima bwiza bwo mu mutwe)
• `Tramadol` (umuti ugabanya ububabare)
• 'Tryptophan'
• Tyramine (iboneka mu biribwa kandi ishobora no kuboneka muri bimwe mu byunganizi)
• 'Viloxazine'
• `Yohimbine`

Indi miti ishobora kugira ingaruka kuri uyu muti

Imiti ikurikira ishobora kandi kugira ingaruka kuri 'Isocarboxazid'. Kubwibyo, niba urimo kuyifata, bwira na muganga wawe ibyayo.

• Barbiturates (urugero: Phenobarbital)
• Utunyangingo tw'imitsi
• Isoniazid (umuti uvura igituntu)
• Imiti ivura ibimenyetso nk'ibicurane, allergie, na grippe
• Imiti ivura diyabete
• Itsinda ry'imiti ya `Phenothiazine` (phenothiazine) (urugero: `Chlorpromazine`, `Prochlorperazine`, `Thioridazine`)

Uru rutonde ntirwuzuye. Bwira muganga wawe imiti yose ufata (wandikiwe na muganga, utayiguze na muganga, imiti y’ibimera, vitamine, intungamubiri). Bwira kandi muganga wawe niba unywa itabi, unywa inzoga, cyangwa ukoresha indi miti. Hari ibintu bishobora kugira ingaruka kuri uyu muti.

Ibindi bintu ugomba kwitondera mugihe ufata uyu muti

• Niba ibimenyetso byawe bitameze neza cyangwa bisa n'aho birushaho kwiyongera, bwira muganga wawe ako kanya. Komeza kuvugana na muganga wawe kugira ngo urebe uko umuti ukora. Bishobora gufata ibyumweru byinshi kugira ngo uyu muti ugire ingaruka nziza. Kubwibyo, ni ngombwa gukomeza gufata umuti nk'uko muganga wawe abikubwira.
• Ibitekerezo byo kwiyahura cyangwa kwiheba gukabije: Ibi ni ingenzi cyane . Mu gihe ufata uyu muti, cyane cyane mu ntangiriro z'ubuvuzi cyangwa nyuma yo guhindura urugero, banza witondere ibitekerezo bishya byo kwiyahura cyangwa kwiheba gukomeye. Nanone, niba ugize impinduka zitunguranye mu byiyumvo byawe, nko kumva uhangayitse, udatuje, urakaye, ufite inzika, urakaye, udashaka kwihagararaho, udatuje cyane, ufite umujinya mwinshi kandi ufite imbaraga nyinshi, cyangwa ufite ingorane zo gusinzira, hamagara muganga wawe vuba. Bwira umuryango wawe kandi ubasabe gukurikirana izi mpinduka.
• Ushobora kumva usinziriye cyangwa uzumva. Rero, kugeza igihe umenye uko uyu muti ukugiraho ingaruka, ntugatware imodoka, ntugakoreshe imashini, cyangwa ngo ukore ikintu cyose gisaba kwitonda. Ntugahaguruke cyangwa ngo wicare vuba cyane, cyane cyane niba ugeze mu za bukuru. Kubikora bizagabanya ibyago byo kuzumva no kugwa.
• Inzoga zishobora kubangamira imikorere y'uyu muti, bityo irinde kunywa inzoga.
• Uyu muti ushobora gutera amaso yumye no kutabona neza. Iyo wambaye indorerwamo z'amaso, ushobora kugira ikibazo. Amavuta yo kwisiga mu maso ashobora gufasha. Niba iki kibazo gikomeje cyangwa gikomeye, gana muganga w'amaso.
• Kuma mu kanwa bishobora kuba ikibazo. Guhekenya ishinya ridafite isukari, kunywa bombo ikomeye idafite isukari, no kunywa amazi menshi bishobora gufasha. Iki kibazo nigikomeza cyangwa kikarushaho gukomera, vugana na muganga wawe.
• Ganira na muganga wawe mbere yo gufata imiti iyo ari yo yose wiyitirira nk'inkorora, ibicurane, na aleriji. Nanone, ntugafate imiti iyo ari yo yose yo kugabanya ibiro udafite uruhushya rwa muganga. Ibintu bimwe muri ibi bicuruzwa bishobora kongera ingaruka mbi.
• Uyu muti ushobora kugira ingaruka ku rugero rw'isukari mu maraso. Niba urwaye diyabete, vugana na muganga wawe mbere yo guhindura indyo yawe cyangwa ingano y'umuti wawe wa diyabete.
• Niba ugiye kubagwa, gupimwa cyangwa kubagwa, bwira muganga wawe ko ufata uyu muti. Uyu muti akenshi ugomba guhagarikwa iminsi 10 mbere y'uko ubagwa.
• Uyu muti ushobora gutuma urugero rwa vitamine B6 rugabanuka. Rero menya neza ko ubona vitamine B6 ihagije mu gihe ufata uyu muti. Vugana na muganga wawe ku byerekeye ibyo kurya na vitamine ufata.

Ni izihe ngaruka mbi zishobora guterwa n'uyu muti?

Kimwe n'indi miti yose, Isocarboxazid ishobora gutera ingaruka mbi ku bantu bamwe. Imwe ni mbi cyane, indi si mbi cyane.

Ingaruka mbi ugomba guhita ubibwira muganga wawe:

Niba ubonye kimwe muri ibi bimenyetso, bwira muganga wawe bidatinze :

• Ubwivumbure bw'uruhu : Gushyuha, kuribwa, uduheri dutukura ku ruhu, kubyimba mu maso, ku minwa, ku rurimi cyangwa mu muhogo.
• Ibimenyetso bya Serotonin Syndrome : Kurakara, urujijo, umutima utera vuba cyangwa utari mwiza, imitsi ikomera cyangwa ihindaguritse, ibyuya byinshi, umuriro mwinshi, gucika intege, gukonja, kuruka, impiswi. Ibi bishobora kuba ibimenyetso by'indwara ikomeye yitwa Serotonin Syndrome, kuko uyu muti wongera urugero rwa serotonin mu bwonko.
• Ibimenyetso by'indwara y'umwijima : Kubabara mu nda yo hejuru iburyo, kubura ubushake bwo kurya, isesemi, amabyi y'ibara ryoroheje, inkari z'umuhondo wijimye cyangwa umukara, uruhu cyangwa amaso bihinduka umuhondo, intege nke cyangwa umunaniro udasanzwe.
• Umuvuduko w'amaraso uri hasi : Kuzunguza, gucika intege, kutabona neza.
• Indwara zo mu mutwe .
• Ukwiyongera gukabije k'umuvuduko w'amaraso : Gutangira kurwara umutwe cyane, isesemi, kuruka, kugorama kw'ijosi, gutera k'umutima vuba cyangwa kutari ku murongo (ibi bishobora kuba ikimenyetso cy'uko umuntu arwaye "Tyramine").
• Ibitekerezo byo kwiyahura cyangwa kwigirira nabi, kumera nabi mu buryo bw'ibyiyumvo, no kwiyongera k'agahinda .

Ingaruka mbi ubusanzwe zitari mbi cyane, ariko zigomba kumenyeshwa muganga mu gihe zikomeje:

Izi ngaruka mbi ubusanzwe ntabwo ziba zikomeye, ariko niba zikomeje cyangwa zikakubangamira, bwira muganga wawe:

• Impatwe
• Kuzungera
• Umunwa wumye
• Umutwe
• Isesemi
• Guhinda umushyitsi

Niba ubonye ibimenyetso bidasanzwe cyangwa bishya mu gihe ufata uyu muti bitaragaragara, bwira muganga wawe. Ushobora kandi gutanga raporo ku ngaruka mbi kuri FDA kuri 1-800-FDA-1088.

Uyu muti uwubika ute?

• Bika uyu muti ahantu abana n'amatungo batagera .
• Bika ku bushyuhe bw'icyumba (hagati ya dogere selisiyusi 15 na 30 / dogere selisiyusi 59 na 86). Bika icupa/agapaki k'umuti ufunze neza .
• Ntugakoreshe imiti yarengeje igihe. Ijugunye.

Uburyo bwo kujugunya imiti itarakoreshejwe cyangwa ishaje:

• Hariho gahunda zo gufata imiti. Ushobora kubimenya kuri farumasi yawe cyangwa polisi.
• Niba bidashoboka, reba ku kirango cy'umuti cyangwa agapapuro karimo kugira ngo urebe niba bikwiye kujugunywa mu myanda cyangwa kujugunywa mu musarani. Niba utabizi neza, baza muganga wawe.
• Niba nta kibazo cyo kujugunya imyanda, kuraho umuti mu gikoresho. Uvange n'ikindi kintu, nk'imyanda y'injangwe, ivu, cyangwa ikawa. Shyira imvange mu gikapu cyangwa mu gikoresho, ufunge neza, hanyuma uyijugunye mu myanda.

Amaherezo, ibintu byo kwibuka

'Isocarboxazid' ni umuti w'ingenzi cyane mu kuvura indwara yo kwiheba. Ariko, kubera ko uri mu itsinda rya 'MAOI', ushobora gutera ingaruka zikomeye ku biribwa (cyane cyane ibiryo birimo 'Tyramine') n'indi miti.

Mu gihe ufata uyu muti, witondere cyane impinduka mu byiyumvo byawe, cyane cyane ibitekerezo byo kwiyahura. Niba ufite ikibazo, bwira muganga wawe ako kanya. Fata urugero rukwiye, mu gihe gikwiye, neza neza nk'uko muganga wawe abikubwira. Icyo gihe ni bwo ushobora kungukirwa n'uyu muti no kunoza ubuzima bwawe bwo mu mutwe.

Iyi nkuru ni incamake gusa. Niba ufite ibindi bibazo kuri uyu muti, nyamuneka vugana na muganga wawe, umufarumasiye, cyangwa undi mukozi w’ubuvuzi.

Isocarboxazide , MAOI, kwiheba, ubuzima bwo mu mutwe, dopamine, serotonin, tyramine, ingaruka mbi, imikoranire y'ibiyobyabwenge