Urukingo rushya rwa cholesterol nyinshi (Hyperlipidemia)? Reka twige kuri Leqvio!

"Muganga, hashize igihe ntatangiye gufata imiti y'iyi cholesterol. Nanone ndagenzura indyo yanjye neza. Ariko urugero rwa cholesterol yanjye ntiruragabanuka..." Ese nawe wumva ikintu nk'iki? Cyangwa hari umuntu wo mu muryango wawe ufite iki kibazo? Mu by'ukuri, kugenzura cholesterol ni ikibazo gikomeye kuri bamwe. Nubwo abantu benshi babona ibisubizo byiza bivuye ku miti yo mu bwoko bwa 'statin', bamwe ntibabibona. Rero, hashyizweho umuti mushya witwa Leqvio kugira ngo ufashe abantu nk'abo. Reka tubiganireho birambuye kandi byoroshye uyu munsi.

Iyi cholesterol nyinshi (Hyperlipidemia) ni iki?

Muri make, hyperlipidemia ni iyo ufite ubwoko bwinshi bw'ibinure (twita ibinure) mu maraso yawe. Twese dukeneye ibinure bimwe na bimwe mu mibiri yacu. Bikora imirimo myinshi y'ingenzi. Ariko iyo birengeje urugero ni bwo ibibazo bitangira. Iyo ibi binure byinshi uko igihe kigenda gihita, ibyago byo kurwara indwara zikomeye nk'indwara z'umutima, gucika imitsi, n'indwara z'umutima biriyongera cyane.

Akenshi tuvuga ku bwoko bubiri bw'ingenzi bw'ibinure.

Byongeye kandi, hari ubundi bwoko bw'ibinure byitwa triglycerides. Si byiza kubirya byinshi cyane.

Ni izihe mpamvu zitera cholesterol nyinshi?

Akenshi, ibi biterwa n'uburyo dusanzwe tubaho, imirire yacu, n'indwara zimwe na zimwe.

• Ibiryo n'ibinyobwa: Inyama zitukura, sosiso, bacon, n'ibiryo birimo amavuta (umuceri ukaranze, khuthu, paratha) birimo ibinure byinshi byuzuye. Kurya ibi bikunze kongera cholesterol.
• Ubuzima:Ibintu nko kunywa itabi, kunywa inzoga nyinshi, guhangayika no kudakora imyitozo ngororamubiri bigira ingaruka zikomeye ku kongera cholesterol.
• Izindi ndwara: Indwara nka diyabete, ibibazo by'umwijima cyangwa impyiko, hypothyroidism, no guhumeka nabi mu gihe umuntu asinziriye nabyo bishobora gutera cholesterol nyinshi.

Intego nyamukuru y'ubuvuzi ni ukugabanya urugero rw'ibinure "bibi" mu maraso. Ibi bishobora kugabanya ibyago byo guhura n'ibibazo bikomeye nko kurwara indwara z'umutima no gucika kw'imitsi.

Umuti wa Leqvio ukora ute?

Statines ni wo muti w’ingenzi wa cholesterol. Ariko, hari abantu badatera cholesterol nkeya uko babyifuza nubwo bafata iyi miti kandi bagakurikiza indyo yuzuye. Abantu bafite ikibazo cya genetiki cyitwa "primary hyperlipidemia" bashobora gukenera imiti irenze imwe.

Leqvio ni umuti mushya waje gufasha aba bantu. Ikintu gikora muri wo ni Inclisiran. Uri mu bwoko bw'imiti yitwa `small interferent RNA (siRNA)`.

Ubu buryo butandukanye rwose n'uko imiti ya statin ikora.

Ese hari umuntu ufite cholesterol ushobora gukoresha Leqvio?

Oya. Uyu si umuti wa buri wese. Leqvio yemewe ku bantu basanzwe bafata indyo yuzuye kandi bafata statine, ariko bagifite urugero rwa cholesterol ruri hejuru .

Uyu muti ushobora kuba wagirwa inama, cyane cyane ku bantu bafite indwara ya gene yitwa `Heterozygous Familyal Hypercholesterolemia (HeFH).` Niba ufite cholesterol nyinshi kandi urugero rwawe ntirugabanuke nubwo ufata imiti ya statine kandi ukurikiza indyo yuzuye, muganga wawe ashobora kukubwira ibya Leqvio. Muganga wawe ni we wenyine ushobora gufata icyemezo niba ibi bikubereye.

Uru rukingo narubona nte?

Leqvio si ikinini, ni urushinge . Ni urushinge rwo mu mubiri. Ntushobora kurutanga mu rugo. Rutangwa n'inzobere mu by'ubuzima (umuganga cyangwa umuforomo) mu bitaro cyangwa ivuriro.

Gahunda yo gukingira ni iyi ikurikira:

1. Urukingo rwa mbere: Uzahabwa urukingo rumwe mbere.

2. Urukingo rwa kabiri:Urukingo rwa kabiri rutangwa nyuma y'amezi 3 nyuma y'urwa mbere.

3. Nyuma y'ibyo: Nyuma y'ibyo, ugomba guterwa urushinge rumwe buri mezi 6 .

Uru rukingo rushobora guterwa mu itako, mu nda, cyangwa inyuma y'ukuboko. Ni ngombwa cyane kubona urukingo rwawe ku gihe kandi ntucikwe na gahunda iyo ari yo yose.

Ni iki uzi ku ntsinzi ya Leqvio?

Ubushakashatsi butatu bw'ingenzi bwakozwe kugira ngo harebwe uburyo Leqvio ifite akamaro kandi itekanye. Ubu bushakashatsi bwakozwe mu gihe cy'amezi 18.

• Ubushakashatsi bubiri: Abitabiriye ubushakashatsi barimo abantu barwaye indwara z'umutima batashoboye kugabanya urugero rwa cholesterol nubwo bakoreshaga imiti ya statine.
• Mu bundi bushakashatsi, abitabiriye ni abafite ikibazo cya cholesterol mu maraso cyitwa `HeFH`.

Muri ubu bushakashatsi, itsinda rimwe ryahawe urukingo rwa Leqvio naho irindi itsinda rihabwa urukingo rwa placebo ariko ntacyo rwagizeho ingaruka. Ibisubizo byari bisobanutse neza.

Ibi bisubizo bigaragaza ko Leqvio ari umuti ushobora kugabanya cyane urugero rwa cholesterol ya LDL idagenzurwa na statins. Urugero rwa cholesterol rukunze kugabanuka mu mezi 3 ya mbere.

Ese uyu muti ugabanya ibyago byo kurwara indwara z'umutima n'imitsi yo mu bwonko?

Iki ni ikibazo cy'ingenzi cyane. Imiti ya statin yagaragaye ko igabanya cholesterol ya LDL kandi ikagabanya ibyago byo kurwara indwara z'umutima na stroke. Ariko Leqvio ni umuti ukora mu buryo butandukanye.

Ariko, kugabanuka gukomeye kwa cholesterol ya LDL bigaragaza ko ibi bishobora kugabanuka mu gihe kizaza. Hari izindi nyigo z'igihe kirekire zirimo gukorwa kugira ngo zemeze ibi.

Ingaruka mbi n'uburyo bwo kuzirwanya?

Kimwe n'indi miti yose, Leqvio ishobora guteza ingaruka mbi nto. Ikunze kugaragara ni ingaruka ziterwa n'aho umuntu atewe urushinge .

• Ubushyuhe aho umuntu yatewe inshinge
• Kuryarya
• Ububabare

Kubera iyo mpamvu, umuganga utanga urukingo ntazatanga urukingo ahantu hatwitswe n'izuba, hafite ibibyimba, cyangwa handuye. Niba warigeze guterwa urushinge mbere kandi ukaba waragize ububabare bwinshi, bibwira muganga cyangwa umuforomo. Hanyuma bashobora guhitamo ahandi hantu.

Uretse ibi, hari n'izindi ngaruka mbi zishobora kubaho. Niba ubonye ibimenyetso bidasanzwe, vugana na muganga wawe vuba.

Kugeza ubu nta mibanire igaragara hagati ya Leqvio n'indi miti. Ariko, ni ngombwa kubwira muganga wawe imiti yose, vitamine, n'ibikomoka ku bimera ufata.