Ihungabana ntiryoroshye nkuko bigaragara. Kubana naryo akenshi ni ikibazo gikomeye. Hari abantu bafata igihe kugira ngo babone umuti ubakwiriye. Hari igihe umuti umwe ushobora kudatanga ihumure ryuzuye. Hari impamvu yabyo. Reka tubisobanukirwe kuva mu ntangiriro.
Kuki indwara yo kwiheba ibaho? Ni gute umuti nka Rexulti wafasha?
Mu magambo make, muri Major Depression Disorder (MDD), urugero rw'ibintu bimwe na bimwe mu bwonko bwacu rugabanuka. Ibyo tubyita neurotransmitters. Ushobora kuba warumvise serotonin na dopamine . Ibi ni byo bintu by'ingenzi bigize imiti bigenzura ibintu nk'uko dutekereza, duteganya, twumva twishimye, twitayeho, kandi dusinzira. Rero iyo ibi bigabanutse, ibimenyetso by'ihungabana bigaragara.
Imiti igabanya ububabare ikunze gutangwa kugira ngo igarure urugero rw'iyi miti. Ariko, rimwe na rimwe, nubwo iyi miti ishobora kugabanya ibimenyetso, ishobora gusiga ibimenyetso bikomeye cyane ku buryo bitakora mu buzima bwa buri munsi. Hari abantu bakira igice gusa iyo bavuwe. Ibi byitwa kwiheba kudakira imiti.
Iki ni cyo gihe abaganga bongeramo undi muti ku muti usanzweho. Ibi byitwa ubuvuzi bw'inyongera . Ni ukuvuga umuti utangwa kugira ngo "ufashe" ubuvuzi busanzweho, kugira ngo "wongere" imikorere yawo.
Rexulti (brexpiprazole) ni umwe mu miti y’inyongera. Iyi ni imiti yo mu bwoko bwa kabiri bwitwa antipsychotics zo mu gisekuru cya kabiri. Iyi miti mishya igira ingaruka nke, nko gutigita, gukomera kw'imitsi, no kwiyongera ibiro, ugereranije n'indi miti ishaje. Rexulti ikora mu kugenzura imiti yo mu bwonko mu buryo butandukanye, ikagabanya ibimenyetso ariko inagabanya ibyago byo kugira ingaruka mbi.
Rexulti ikora ite imbere mu mubiri?
Rexulti ikora cyane cyane mu kongera urugero rwa dopamine na serotonin mu bwonko. By'umwihariko, uyu muti uhuza na bimwe mu byuma bifasha mu bwonko kurekura dopamine ifatiwe. Nanone utera imbaraga serotonin, ishobora gufasha kunoza ibyiyumvo no kugabanya ibimenyetso by'ihungabana.
Uyu muti nkwiye kuwukoresha nte?
Rexulti ni ikinini ufata rimwe ku munsi. Ushobora kugifata uri kurya cyangwa utagifashe. Akenshi gitangirana n'igipimo gito cyane, hafi kimwe cya kabiri cya miligarama (0.5mg). Nyuma yaho, muganga wawe azagenda yongera igipimo buhoro buhoro bitewe n'uko umubiri wawe witwara, indi miti ufata, n'uburyo impyiko zawe cyangwa umwijima bikora. Igipimo ntarengwa cyo kuvura indwara yo kwiheba ni miligarama 3 (3mg) ku munsi.
Igikuru ni ugukurikiza amabwiriza ya muganga wawe neza. Gufata imiti yawe ku gihe gikwiye buri munsi ni bwo buryo bwonyine bwo kuringaniza imikorere y'ubwonko bwawe, kugenzura ibimenyetso by'indwara, no gukora neza.
Wibuke ko uyu muti utagukiza ako kanya. Bishobora gufata ibyumweru byinshi kugira ngo umenye impinduka mu bimenyetso byawe. Kubwibyo, gukoresha uyu muti buri gihe ni ryo pfundo ryo kugira icyo ugeraho.
Ubushakashatsi buvuga iki ku bijyanye n'intsinzi y'uyu muti?
Ubushakashatsi bubiri bukomeye bwakozwe kugira ngo hamenyekane uburyo Rexulti ifite akamaro kandi itekanye mu kuvura indwara yo kwiheba. Muri ubu bushakashatsi, itsinda rimwe ry'abantu ryahawe Rexulti, irindi tsinda rihabwa placebo. Ibi byatumye abashakashatsi bapima ingaruka nyazo z'uyu muti.
Dukurikije ibyavuye muri ubu bushakashatsi, nyuma y'ibyumweru 6, abantu benshi bafashe Rexulti hamwe n'imiti isanzwe yo kurwanya indwara zo kwiheba bagaragaje ibimenyetso by'indwara yo kwiheba biri hagati y'ibisanzwe n'ibisanzwe.
Imbonerahamwe iri hepfo igaragaza ibisubizo gusa. Uko amanota aba make, niko ibimenyetso birushaho kuba bibi.
| Ikipe | Igipimo cy'ihungabana mu ntangiriro (amanota mpuzandengo) | Igipimo cy'ihungabana nyuma y'ibyumweru 6 (impuzandengo y'amanota) | Itandukaniro mu manota (izamuka) |
|---|---|---|---|
| Isomo rya 1: Placebo (ibinini by'indorerwamo) | 27.3 | 22.1 | -5.2 |
| Inyigo ya 1: Rexulti 2 mg | 26.9 | 18.5 | -8.4 |
| Isomo rya 2: Placebo (ibinini by'indorerwamo) | 26.5 | 20.2 | -6.3 |
| Inyigo ya 2: Rexulti 1 mg | 26.5 | 18.9 | -7.6 |
| Inyigo ya 2: Rexulti 3 mg | 26.5 | 18.2 | -8.3 |
Nkuko mubibona muri ubu bushakashatsi, abafashe Rexulti bagaragaje impinduka zikomeye mu bimenyetso byabo. Ubu bushakashatsi kandi bwemeje ko ubushobozi bwabo bwo gukora mu buzima bwa buri munsi, mu muryango, mu muryango, no ku kazi/ku ishuri bwarushijeho kuba bwiza.
Namenya nte niba umuti ukora?
Mu byumweru cyangwa amezi make, uzatangira kubona ko ibimenyetso byawe byarushijeho kuba byiza. Umuryango wawe n'inshuti zawe nabo bazabona itandukaniro riri muri wowe.
- Imitekerereze irushijeho kuba myiza
- Ingufu nyinshi cyangwa imbaraga nyinshi
- Gusinzira neza
- Ushishikajwe n'ibikorwa wakundaga gukora.
- Kugabanuka k'imihangayiko cyangwa impungenge
- Kongera ubushake bwo kurya
- Kwibanda neza kurushaho
Izi mpinduka ntizibaho mu ijoro rimwe. Zibaho buhoro buhoro. Kubwibyo, ni ngombwa gukurikirana impinduka mu bimenyetso byawe. Igihe ugomba gufata imiti gitandukanye bitewe n'umuntu ku wundi. Hari abantu bayikenera igihe gito, abandi bakayikenera igihe kirekire.
Igikuru ni ukudahagarika gufata imiti yawe utabanje kuvugana na muganga wawe kuko ubona ko ibimenyetso byawe birimo kugenda birushaho koroha. Iyo ubikoze, ibimenyetso byawe bishobora kongera kwiyongera. Niba utameze neza nyuma y'amezi make, bibwira muganga wawe nawe.
Ingaruka mbi n'uburyo bwo kuzirwanya?
Ingaruka mbi zikunze kugaragara za Rexulti ni ukwiyongera ibiro, gusinzira, isereri, ibimenyetso bisa n'ibicurane, no kubura ituze (kunanirwa kwicara neza). Ibi ntibibaho kuri buri wese, ariko akenshi bigabanuka uko igihe kigenda gihita.
| Ingaruka mbi | Icyo ushobora gukora |
|---|---|
| Kongera ibiro, kwiyongera k'umusemburo/isukari | Garagaza ubuzima bwiza. Imyitozo ngororamubiri, ongeramo imboga, imbuto, n'inyama zidafite ibinure mu mirire yawe. Gabanya amavuta, umunyu n'isukari. Muganga wawe azagenzura buri gihe ibiro byawe, umuvuduko w'amaraso, cholesterol n'isukari. |
| Gusinzira cyangwa isereri | Niba wumva usinziriye, fata umuti mbere yo kuryama nijoro. Haguruka buhoro buhoro uva aho wicaye cyangwa uryamye. Irinde gutwara imodoka kugeza igihe umenye uko umuti ukugiraho ingaruka. |
| Kudatuza (Akathisia) | Ibi bivuga kumva udashobora kuguma ahantu hamwe no kuzerera gusa. Imyitozo ngororamubiri yoroheje nko kugenda no kunanura imitsi ishobora gufasha. Humura ubwenge bwawe ukoresheje ibintu nk'imyitozo yo guhumeka no gutekereza cyane. Gabanya ibintu nk'ikawa, icyayi, na kola, kuko bishobora kongera iyi mitekerereze. |
| Kudashobora kwihanganira ubushyuhe | Uyu muti ushobora kugabanya ubushobozi bw'umubiri bwo kwikonjesha. Irinde ubushyuhe bukabije no kubura amazi. Ambara imyenda yoroheje kandi unywe amazi menshi. |
| Kubabara mu nda, kuribwa mu nda, mu kanwa humutse | Fata umuti hamwe n'ibiryo. Niba umunwa wawe wumye, nywa amazi make kenshi, nywa uduce twa barafu, cyangwa uhekenya shinya idafite isukari. Niba ufite impatwe, nywa amazi menshi kandi urye ibiryo birimo fibre nyinshi (ingano, ibishyimbo, imbuto). |
Ibi ni byo bintu bikunze kubaho. Niba hari ubwo burwayi bukomeje cyangwa burushaho kwiyongera, menya neza ko wabibwiye muganga wawe.
Ese hari ibibazo bishobora kubaho ku yindi miti? (Imikoreshereze y'imiti)
Yego. Imiti imwe n'imwe ishobora kongera cyangwa kugabanya imikorere ya Rexulti, cyangwa ikongera ibyago byo kugira ingaruka mbi, iyo ifashwe na Rexulti. Urugero, imiti imwe n'imwe irwanya udukoko (urugero: ketoconazole), imiti imwe n'imwe irwanya udukoko (urugero: clarithromycin), imiti imwe n'imwe igabanya ubukana (urugero: fluoxetine, paroxetine), ndetse n'umutobe w'imbuto z'umuzabibu bishobora guhindura ingaruka za Rexulti.
Kubwibyo, ni ingenzi cyane kubwira muganga wawe imiti yose, vitamine, n'ibikomoka ku bimera urimo gufata, kugira ngo ashobore guhindura ingano ya Rexulti ikubereye.
Ni ibihe bipimo bigomba gukorwa mu gihe cyo kuvurwa?
Muganga wawe azagukorera ibizamini kugira ngo akurikirane ubuzima bwawe mbere yuko utangira gufata imiti no mu gihe uyifata.
- Uburemere bwawe, uburebure bwawe, n'umuzenguruko w'ikibuno cyawe.
- Umubare wuzuye w'amaraso (CBC).
- Gupima cholesterol mu maraso n'isukari (Kwiyiriza lipide mu maraso no gusuzuma isukari).
- Umuvuduko w'amaraso.
- Ikizamini cya AIMS kugira ngo harebwe niba hari imikorere idasanzwe (urugero: imikorere y'amaguru idakozwe ku bushake).
Ibi bizamini ni bwo buryo bwonyine bwo kumenya neza uburyo umuti uzagira ingaruka ku mubiri wawe.
Ubutumwa bwo kujyana mu rugo
- Rexulti ni umuti "w'inyongera" utangwa usibye imiti isanzwe ikoreshwa mu kuvura indwara yo kwiheba, kugira ngo wongere imikorere yayo.
- Ibi bikora binyuze mu kuringaniza imiti iri mu bwonko ijyanye n'ibyishimo n'ibyishimo.
- Fata umuti buri gihe, nk'uko muganga wawe yabigutegetse, ku gipimo cyagenwe.
- Nubwo ibimenyetso byawe byarushaho kumera neza, irinde guhagarika imiti utabanje kugisha inama muganga wawe.
- Menya ingaruka mbi nko kongera ibiro, gusinzira no kubura umutuzo. Niba bikubangamiye, vugana na muganga wawe.
- Ni ngombwa kumenyesha muganga wawe indi miti yose, vitamine, n'imiti gakondo ufata.
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