Ese umwana wawe akunze kugira umuriro nta mpamvu? Reka twige kuri izi ndwara za SAID (indwara zifata umubiri)!

Ese umwana wawe rimwe na rimwe arwara umuriro nta bicurane cyangwa indi ndwara iyo ari yo yose? Ese umuriro uraza, ugashira mu minsi mike, hanyuma ukagaruka nyuma y'iminsi mike? Hari ababyeyi bahura n'ibintu nk'ibyo. Uyu munsi rero tugiye kuvuga ku mpamvu ikunze kugaragara kandi igoye kubona itera umuriro. Ibi byitwa SAIDs (Indwara zitera indwara zifata umubiri) . Mu bihe byashize, ibi byitwaga `(Indwara zifata umubiri igihe kirekire)` cyangwa `(Indwara zifata umubiri igihe kirekire)`.

Ibi bintu bya SAID ni iki? Reka tubisobanukirwe mu buryo bworoshye!

Mu magambo make, SAID ni itsinda ry'indwara ziterwa n'ikibazo cy'imikorere mibi cyangwa ikibazo cy'imikorere mibi mu budahangarwa bw'umubiri wacu . Muri iki gihe, nta bwandu bwo hanze (nk'agakoko cyangwa bagiteri), umubiri wacu utera ububyimbirwe gusa. Ni nk'aho ubudahangarwa bw'umubiri wacu burimo kugenda burushaho kwiyongera.

Tekereza nawe, dufite itsinda ry'abasirikare mu mibiri yacu (ni ukuvuga ubudahangarwa bw'umubiri). Akazi kabo ni ukurwanya mikorobe zitera indwara iyo zije. Ariko mu mubiri w'umuntu urwaye SAID, abo basirikare rimwe na rimwe bararakara bagateza ibibazo mu mubiri.

Noneho ushobora kwibaza niba ibi ari ibintu nk'ibi `(indwara ziterwa no kwirwanaho)` (ni ukuvuga indwara ziterwa no kwirwanaho). Urugero, `(rubagimpande)` cyangwa `(lupus)` birasa. Oya, ibi byombi biratandukanye gato. Mu ndwara ziterwa no kwirwanaho, ikibaho ni uko ubudahangarwa bw'umubiri wacu bwibasira uturemangingo twabwo twiza cyangwa twigenga. Ariko muri SAID, ikibazo kiri ku budahangarwa bw'umubiri karemano.

Indwara za SAID zikunze kugaragara cyane kurusha indwara ziterwa n’ubwiyongere bw’umubiri. Inyinshi muri zo ni iz’uruhererekane rw’umubiri , bivuze ko ziterwa n’impinduka mu miterere y’uturemangingo cyangwa ubwoko butandukanye bw’uturemangingo.

Indwara za SAID zikunze gutangirira mu bwana cyangwa mu bwana . Ariko si ko bigenda buri gihe. Umwana wawe ashobora kugira ibihe cyangwa ibitero by'umuriro n'ibindi bimenyetso. Umwana wawe ashobora kuba adafite ibimenyetso na gato hagati y'ibitero. Nta muti wa SAID uhari. Ariko, hari uburyo bwo kuvura bushobora gufasha mu kugabanya ibimenyetso mu bihe byinshi.

Ni ubuhe bwoko bw'ingenzi bwa SAIDs?

Abashakashatsi ubu bamaze kubona ubwoko bwa SAID bugera kuri 60, kandi hari n'ubundi buri kuvumburwa. Reka turebe bumwe mu bwoko bukunze kugaragara cyane.

• Indwara y'umuriro wo mu bwoko bwa Mediterane (FMF): Iyi ni yo ndwara ikunze kugaragara mu ndwara z'umuriro zivuka mu buryo bw'uturemangingo, kandi zigaruka kenshi. Ishobora gutera ububabare mu nda, mu gituza no mu ngingo z'umwana .
• Umuriro uhoraho, aphthous-stomatitis, pharyngitis, adenitis (PFAPA): Ibi bikunze gutangira ku bana bato mbere y'imyaka 4. Iyi ndwara ishobora kugabanuka mu buryo butunguranye nyuma y'imyaka 10.
• Indwara y’ingirabuzimafatizo iterwa n’urumogi (Tumor necrosis factor receptor-associated periodic syndrome): Ibi bishobora kubaho mu bwana, mu gihe cy’ingimbi, ndetse rimwe na rimwe no mu gihe cy’ubukure.
• Ubukene bwa Mevalonate kinase (MKD): Mbere yitwaga hyper-IgD syndrome, ibi akenshi bitangira ku bana bari munsi y'umwaka umwe.
• Indwara ziterwa no kubyimbirwa mu buryo bwa autoimmune ziterwa na NLRP3: Iyi yari isanzwe yitwa cryopyrin-associated periodic syndromes (CAPS). Hari izindi nkomoko eshatu muri iyi.
• Indwara ya Still y’abantu bakuru (AOSD): Iyi ni ubwoko bw’indwara ya rubagimpande y’abana itera indwara y’imitsi (JIA) itera abantu bakuru.
• Indwara ya granulomatous ifitanye isano na NOD-2 (Blau syndrome): Ibi bikunze gutangira mbere y'imyaka 4. Bigira ingaruka cyane cyane ku ruhu rw'umwana, amaso n'ingingo .

Ni ibihe bimenyetso bya SAID? Twabimenya dute ?

Ibimenyetso bya SAID bikunze gutangirira mu bwana. Ikimenyetso gikunze kugaragara cyane ni umuriro uhoraho cyangwa uhoraho . Abantu bakunze kutagira ibimenyetso hagati y’ibitero. Ariko, hashobora kubaho ibindi bimenyetso byihariye kuri buri bwoko bwa SAID.

Reka turebe ibimenyetso byihariye by'ubwoko butandukanye bwa SAID twavuze haruguru:

• FMF: Ibi bishobora gutera ububabare bukomeye mu nda y'umwana, mu gituza no mu ngingo, hamwe no kubyimba . Hari igihe, hari uduheri dushobora kugaragara ku maguru yo hasi cyangwa ku kaguru. Tekereza, umwana ahita agira ububabare mu nda n'umuriro. Iyo ababyeyi bahangayikishijwe bakabajyana kwa muganga, bashobora gutekereza ko ari appendicitis. Ariko nyuma biragabanuka bikagaruka nyuma y'iminsi mike.
• PFAPA: Ibi bishobora gutera ibimenyetso nko kubabara mu muhogo, ibisebe byo mu kanwa, no kubyimba kw'uturemangingo tw'imitsi mu ijosi .
• IMITEGO: Ibi bishobora gutera ubukonje, ububabare bw'imitsi mu gituza no mu maboko , ndetse n'uduheri dutukura dutangirira ku maboko no ku maguru tugakwirakwira mu mubiri wose.
• MKD: Muri ibi nanoneUshobora kumva utameze neza bitewe n'ubukonje, kuribwa umutwe, kubabara mu gifu, kubura ubushake bwo kurya, ndetse n'ibimenyetso bisa n'ibicurane.
• Indwara za NLRP3: Izi zishobora gutera ibimenyetso nko kurwara uduheri ku ruhu, kuribwa umutwe, kurwara indwara, kubabara ingingo, no gutukura amaso (conjunctivitis) .
• AOSD: Iyi ni indwara ikunze gutera uduheri ku ruhu, ububabare bw'ingingo, n'ububabare bw'imitsi . Hari abantu bashobora no kubabara mu muhogo, kubabara mu nda, umunaniro ukabije, no kubabara umubiri.
• Indwara ya Blau: Ibi bishobora gutera ibisebe ku ruhu rw'umwana wawe mu biganza, mu birenge, cyangwa ku mubiri . Bishobora kandi gutera ububabare mu ngingo no mu maso .

Kuki izi SAID ziba? Ni izihe mpamvu?

Inyinshi muri SAID ni indwara zikomoka ku maraso . Ni ukuvuga ko buri ndwara iterwa n'ihindagurika (variant) muri gene runaka.

Reka turebere hamwe imiterere y’uturemangingo igira ingaruka ku bwoko bwinshi bw’ingenzi bwa SAID:

• FMF: Ibi biterwa na gene yitwa `(MEFV gene)`. Iyi gene iyobora uburyo bwo gukora poroteyine yitwa `(pyrin)`.
• PFAPA: Impamvu nyayo y'ibi ntiraboneka .
• IMITEGO: Ibi biterwa na gene yitwa `(gene ya TNFRSF1A)`. Ibi nibyo bitanga amabwiriza yo gukora poroteyine yitwa `(receptor y'ibintu bitera tumor necrosis - TNFR)`.
• MKD: Impamvu y'ibi ni gene yitwa `(MVK gene)`. Ibi bitegeka ikorwa rya poroteyine yitwa `(mevalonic kinase)`.
• Indwara za NLRP3: Ibi biterwa na gene yitwa `(gene ya NLRP3)`. Ibi bitanga amabwiriza yo gukora poroteyine yitwa `(cryopyrin)`.
• AOSD: Impamvu nyayo y'ibi ntiraboneka .
• Indwara ya Blau: Ibi biterwa na gene yitwa `(gene ya NOD2)`. Ibi bitegeka ikorwa rya poroteyine yitwa `(NOD2)`.

Ese izi SAID zishobora gutera izindi ngorane?

Yego, ibi bishobora guteza ibibazo iyo bitavuwe neza . Iyo ububyimbirwe bukomeje mu mubiri, bishobora gutera indwara yitwa "amyloidosis." Ni ukuvuga ko ubwoko bwa poroteyine bushyirwa mu mpyiko zacu. Ibi bishobora kwangiza impyiko burundu . Niyo mpamvu ari ngombwa gusuzuma indwara hakiri kare no kuyivura.

Ni gute umuganga asuzuma iyi ndwara ya SAID?

Mu by’ukuri, gusuzuma izi ndwara ziterwa no kubyimbirwa bishobora kugorana gato , kuko ibimenyetso byazo bishobora gusa n’izindi ndwara zikomeye nka lupus cyangwa kanseri nka lymphoma. Kubwibyo, ni ngombwa kubonana na muganga ufite ubumenyi bwihariye mu ndwara ziterwa no kubyimbirwa, inzobere mu ndwara zo mu maraso, kugira ngo amenye neza kandi acunge neza ikibazo cy’umwana wawe.

Umuganga w’indwara z’imitsi y’umwana wawe azakoresha ibintu byinshi kugira ngo amenye indwara za SAID. Azakubaza ibimenyetso by’umwana wawe ndetse niba hari umuntu wo mu muryango wawe ufite izi ndwara (amateka y’umuryango). Muganga ashobora gukeka ko umwana wawe ashobora kuba afite indwara y’umuriro ihoraho iyo:

• Iyo umwana ahora afite umuriro .
• Niba hari umuntu mu muryango ufite amateka yo kurwara umuriro nk'uyu kenshi .
• Niba umwana ari mu itsinda ry'abantu bakunda kugira umuriro nk'uyu rimwe na rimwe .

Ni ibihe bizamini biri gukorwa kuri ibi?

Kugira ngo yemeze ko umwana wawe arwaye indwara ya rubagimpande, umuganga w’indwara za rubagimpande ashobora kukugira inama yo gupima indwara zitandukanye. Ibi bishobora kuba birimo:

• Ibizamini byo muri laboratwari: Ibizamini nka ``C-reactive protein (CRP)`` na ``complete blood count (CBC)`` bishobora gukoreshwa mu gusuzuma ububyimbirwe mu mubiri. Ibi bizamini biba ari byiza mu gihe cy'umuriro "attack" kandi bigasubira ku buryo busanzwe iyo "attack" irangiye.
• Ikizamini cy'inkari: Ikizamini cya poroteyine y'inkari gishobora gukorwa kugira ngo harebwe niba poroteyine nyinshi mu nkari. Muri MKD, ikizamini cy'inkari kireba aside organic (aside irimo atome imwe ya karuboni) gishobora kugaragaza urugero rwinshi rwa aside mevalonic.
• Gupima imiterere y’uturemangingo: Ibi bishobora gusuzuma ubwoko bw’uturemangingo. Ariko, bamwe mu bana bafite indwara za SAID bashobora kutabona ubwoko bw’uturemangingo, ibyo bikaba byatanga ibisubizo bibi ku bipimo.

Ni ubuhe buryo bwo kuvura izi ndwara za SAID?

Uburyo bwo kuvura indwara za SAID butandukana bitewe n'ubwoko n'uburemere bw'indwara . Nta muti uhari wo kuvura izi ndwara. Ariko , ibimenyetso by'umwana wawe bishobora kugenzurwa n'imiti . Niba umwana wawe afite ibisebe bike gusa mu mwaka, ushobora kumuha imiti igabanya ububabare nka imiti idakoresha steroide igabanya ubukana (NSAIDs) kugira ngo igabanye ibimenyetso bye. Ariko, niba indwara ikomeye cyane, muganga wawe ashobora kukugira inama y'ubundi buryo bwo kuvura.

Dore bimwe muri byo:

• FMF: Umuti witwa `(colchicine)` urashobora gukoreshwa mu kurwanya ibi. Ibi bigabanya ububyimbirwe. Niba umwana adashobora gufata colchicine, ubwoko bw'umuti `(biologic)` witwa `(canakinumab)` burashobora kugeragezwa.
• PFAPA: Steroids (ubusanzwe prednisone) ishobora gutangwa kugira ngo igabanye igihe cyo "gutera" kwa PFAPA. Ku bana bamwe, cimetidine, umuti ukoreshwa mu kuvura ibisebe byo mu gifu, na wo ushobora gufasha mu kugenzura ibimenyetso.
• IMIGOZI: Umuti witwa "canakinumab" ukunze kugira akamaro kuri ibi. Nanone, ibimenyetso bishobora koroherwa n'imiti igabanya ububabare yandikiwe na muganga, nka "glucocorticoids".
• MKD:Canakinumab ni umuti mwiza uvura indwara ya MKD. Gutanga imiti igabanya ubukana bwa NSAID cyangwa steroid mu gihe cy' "igitero" nabyo bishobora gufasha.
• Indwara za NLRP3: Imiti igabanya ubukana bw'umubiri nka canakinumab, rilonacept, na anakinra ikoreshwa neza kuri ibi.
• AOSD: Ubwoko butandukanye bw'imiti igabanya ubushyuhe bukoreshwa kuri AOSD. Urugero, harimo imiti igabanya ubushyuhe, imiti igabanya indwara igabanya ububabare bw'ingingo (DMARDs), n'imiti ivura indwara.
• Indwara ya Blau: Bitewe n'ibimenyetso by'umwana wawe, ashobora kugerageza imiti igabanya ubudahangarwa bw'umubiri, imiti igabanya ubukana bw'indwara ya tumor necrosis factor (TNF), cyangwa imiti igabanya ubukana bw'amaso.

Ese ibi bintu bya SAIDs birahoraho? Cyangwa bizashira?

Hari indwara zimwe na zimwe ziterwa no kubyimbirwa mu mubiri zibaho ubuzima bwose . Hari izindi zishobora kumara imyaka mike zikagenda uko umuntu akura. Hari izindi zibaho ubuzima bwose, ariko uko igihe kigenda gihita, inshuro n'ubukana bw'ibitero bishobora kugabanuka. Muganga w'umwana wawe ashobora kuguha amakuru yihariye yerekeye indwara y'umwana wawe.

Kurera umwana urwaye indwara itera ububabare bw’umubiri bishobora kugorana. Niba warigeze kugira ikibazo cya SAID, ushobora gukoresha ibyakubayeho kugira ngo urusheho gushyigikira ubuvuzi bw’umwana wawe. Ushobora kandi gukoresha ibyakubayeho kugira ngo ufashe umwana wawe kumenyera iki kibazo cy’ubuzima bwe bwose.

Igikuru ni ukugana abaganga b'inzobere bafite ubumenyi ku ndwara za SAID. Abaganga nk'abo bashobora kugufasha mu kuvura ibimenyetso by'umwana wawe no kumufasha kugira ubuzima bwiza bushoboka mu bwana bwe.

Ubutumwa bwa nyuma bwo kujyana mu rugo

Rero, ndizera ko ufite igitekerezo kuri SAIDs twavuze uyu munsi. Wibuke ko niba umwana wawe afite umuriro udasanzwe kandi udasobanutse, vugana na muganga kuri byo . Ntukabirengagize gusa, utekereza ko ari ibisanzwe.

• SAID ni itsinda ry'indwara zikunze gutera umuriro kandi ziterwa n'ikibazo cy'ubudahangarwa bw'umubiri.
• Ibi akenshi biba ari imiterere y’umubiri kandi bitangira bakiri bato.
• Nubwo nta muti urambye uhari, hari uburyo bwo kuvura bushobora kugenzura ibimenyetso.
• Ni ngombwa gushaka uburyo bwo gusuzuma no kuvurwa neza na muganga w’inzobere (Rheumatologist).
• Iyo ubuvuzi butangiye hakiri kare, ingorane nka amyloidosis zishobora kwirindwa kandi umwana akabaho ubuzima busanzwe.

Niba ufite ibindi bibazo kuri ibi, ntutindiganye kubaza muganga w'umuryango wawe cyangwa muganga w'abana.

SAIDs , Indwara zo mu mubiri ziterwa no kubyimbirwa, Umuriro ukunze kubaho, Indwara z’uturemangingo, Umuriro mu bana, Ubudahangarwa bw’umubiri, Inzobere mu ndwara za rubagimpande