Maplatelet ako akakwira here? Ngatitaurei nezveThrombocytosis!

Wakamboonekwawo uine maplatelet akawanda muropa rako here? Kana kuti pane mumwe munhu waunoziva ane chirwere ichi here? Zvakajairika kuti unzwe kutya zvishoma paunonzwa chimwe chinhu chakadai. Asi usazvidya mwoyo, nhasi tichataura nezvechirwere ichi chinonzi Thrombocytosis nenzira iri nyore yaunogona kunzwisisa.

Chii chinonzi thrombocytosis? Zvichitaurwa zviri nyore…

Zvichitaurwa zviri nyore, thrombocytosis inoitika kana uine maplatelet akawandisa muropa rako. Iye zvino ungave uchibvunza kuti, "Chii chinonzi maplatelet?" Mubvunzo unokosha zvikuru!

Maplatelet rudzi rwemasero madiki anowanikwa muropa redu. Basa rawo guru nderekumisa kubuda kweropa kana paine ropa, senge kana paine ronda. Anoshanda sedam diki.

Asi chii chinoitika kana huwandu hwemaplatelet hukawedzera zvakanyanya? Ropa rako rinogona kukobvu uye kunamira. Mune zvimwe zviitiko zvakakomba, maplatelet aya akawandisa anogona kukonzera kuumbwa kweropa rine njodzi mukati metsinga dzeropa. Izvi zvinogona kuwedzera njodzi yezvirwere zvakaita sestroke kana kurwara nemoyo .

Zvisinei, havasi vese vane thrombocytosis vane njodzi yakaenzana. Kuoma kwechirwere ichi, uye kuti unoda kurapwa here kana kuti kwete, zvinoenderana nechikonzero chacho.

Kune mhando mbiri huru dze thrombocytosis:

Ehe, vanachiremba vakaona mhando mbiri huru dzechirwere ichi. Ngatitaurei nezvazvo zvishoma.

1. Essential Thrombocythemia (ET) kana kuti Primary Thrombocytosis

Ichi chirwere cheropa chisingawanzoitiki. Chinoitika kana mupfupa wako - fekitori yemasero eropa iri mukati memapfupa ako - ichigadzira maplatelet akawandisa. Funga nezvazvo, masero mazhinji eropa mumiviri yedu anogadzirwa mumupfupa uyu. Munhu ane essential thrombocythemia ane kugadzirwa kwakanyanya kwemaplatelet nekuda kwekusagadzikana mukugadzirwa kwemasero eropa uku.

Chirwere ichi, chinonzi ET (Essential Thrombocythemia) , chinoonekwa sechirwere chinowanzoitika muboka reropa rinonzi Myeloproliferative Neoplasm (MPN) .

2. Reactive Thrombocytosis kana kuti Secondary Thrombocytosis

Iyi ndiyo mhando yeThrombocytosis inonyanya kuitika. Apa ndipo apo muviri wako unogadzira maplatelet akawanda nekuda kwechimwe chirwere, hutachiona, kukuvara, kuvhiyiwa, kana kubviswa kwepleen. Zvichitaurwa zviri nyore, muviri wako unoita chimwe chinhu uye unowedzera huwandu hwemaplatelet. Izvi ndizvo zvinoitika kana muviri wako waita chimwe chinhu.Reactive thrombocytosis inowanzova yenguva pfupi, zvichireva kuti kana chikonzero chacho chagadziriswa, huwandu hwemaplatelet hunodzoka pahwakajairika.

Ndiani anowana thrombocytosis?

Chirwere ichi chinowanzoonekwa muvanhu vane makore anopfuura makumi matanhatu. Zvakare, zvinonzi rudzi rwechirwere chinonzi Essential Thrombocythemia (ET) runowanikwa muvakadzi kaviri kupfuura varume.

Ndezvipi zvikonzero zve thrombocytosis?

Zvikonzero zvemarudzi maviri atakurukura kare zvakasiyanawo.

Zvinokonzera Essential Thrombocythemia (ET)

Essential Thrombocythemia (ET) chirwere chinowanikwa mumajini. Hachisi chinhu chaunozvarwa nacho. Chinokonzerwa nekuchinja, kana kuti kuchinja-chinja, mumajini mamwe anobatanidzwa mukugadzirwa kwemaplatelet. Izvi zvinoita kuti bone morrow yako igadzire maplatelet akawandisa.

Vanhu vanopfuura hafu vane Essential Thrombocythemia (ET) vane shanduko mujini reJAK2 . Kuchinja kwemajini eCALR kana MPL kwakajairikawo.

Masayendisiti haasati akwanisa kunyatsoona kuti chii chinokonzera kuchinja kwemajini uku, asi kutsvagurudza kuri kuenderera mberi.

Zvinokonzera Reactive Thrombocytosis

Rudzi urwu runoitika nekuti muviri wako unogadzira maplatelet akawanda zvichienderana nemamiriro akasiyana-siyana. Kana, dzimwe nguva, zvinogonawo kunge zvichikonzerwa nekuti maplatelet ekare anoungana panzvimbo pekuparadzwa nekukurumidza.

Heano zvimwe zvinhu zvinogona kukonzera Reactive Thrombocytosis :

• Anemia , kunyanya anemia yekushaikwa kwesimbi .
• Zvimwe zvirwere zveropa.
• Mamwe marudzi egomarara .
• Utachiona, hwakadai sepneumonia .
• Zvirwere zvinozvimba - zvirwere zvinokonzera kuzvimba mumuviri, zvakaita se rheumatoid arthritis.
• Kukuvara .
• Kukundikana kweitsvo .
• Mimwe mishonga.
• Kuvhiyiwa, kunyanya kuvhiyiwa kwedumbu.
• Kubviswa kwetsvina .
• Kurapa kushomeka kwevhitamini B12 .

Rondedzero iyi inongosanganisira zvikonzero zvishoma zvakajairika. Panogona kuva nezvimwe zvikonzero zvakawanda zveReactive Thrombocytosis .

Ndezvipi zviratidzo zve thrombocytosis?

Kazhinji, vanhu vane maplatelet akawanda havaratidzi zviratidzo, kunyanya pakutanga. Kana uine Reactive Thrombocytosis , unogona kuona zviratidzo zvechirwere chakakonzera chirwere ichi.

Zvisinei, kana zviratidzo zvikaitika, zvinowanzoenderana nekubuda ropa zvisina kujairika uye kuumbwa kweropa mumuviri wako. Unogona kuona zviratidzo zvakaita se:

• Musoro .
• Inokuvara zviri nyore.
• Kunzwa kushaya simba, dzungu, kana kusuruvara.
• Kubuda ropa mumhino, mumuromo, uye mumatadza.
• Kubuda ropa mudumbu kana muura.

Vamwe vanhu vane Essential Thrombocythemia (ET) vanogona kuva nechirwere chinonzi Erythromelalgia . Izvi zvinokonzera kurwadziwa, kuzvimba, uye kutsvuka mumaoko netsoka. Vanogonawo kunzwa kusanzwa uye kukwenya mumaoko netsoka.

Muzviitiko zvakakomba, thrombocytosis inogona kukonzera kuumbwa kweropa mudumbu (semuenzaniso, Budd-Chari syndrome ) uye kuwedzera njodzi yekurohwa nesitiroko kana kurwiswa nemoyo .

Thrombocytosis inoonekwa sei?

Nekuti thrombocytosis kazhinji haikonzeri zviratidzo, chiratidzo chekutanga chaunowana ndechekuti bvunzo yeropa yenguva dzose (semuenzaniso, Complete Blood Count - CBC ) inoratidza kuwanda kwemaplatelet.

Thrombocytosis inotsanangurwa seine maplatelet anopfuura 450,000 pa microliter yeropa. Kana huwandu hwemaplatelet ako hwakakwira, chiremba wako angangoraira kuti ropa rako riongororwezve mumavhiki mashoma kuti vaone kana huwandu hwacho huchiri hwakakwira. Kuwedzera kamwe chete kwehuwandu hwemaplatelet uye kudzokera kune zvakajairika hazviwanzo kuva dambudziko. Zvisinei, huwandu hwacho hunoramba hwakakwira hunogona kuratidza chirwere chiripo.

Kana paine reactive thrombocytosis , kuziva chikonzero chakakonzera chirwere ichi (semuenzaniso, iron deficiency anemia , cancer, hutachiona) kunogona kubatsira vanachiremba kuona nekurapa chirwere ichi. Zvisinei, kana chiremba asingakwanise kuwana chikonzero chechipiri chakadaro, vachaita mimwe miedzo kuti vaone kana uine Essential Thrombocythemia (ET) .

Miedzo iyi inogona kusanganisira:

• Kuongororwa kweropa rekunze:Izvi zvinotarisa kana maplatelet ari muropa rako asina kurongeka.
• Kuongororwa kweDNA/majini: Izvi zvinogona kuona shanduko dzemajini dzakadai seJAK2 , idzo dzinowanzobatanidzwa neET (Essential Thrombocythemia) .
• Kuongororwa kwemapfupa emubofu: Izvi zvinotarisa masero asina kujairika mubofu rako.

Thrombocytosis inorapwa sei?

Kana usina zviratidzo, ungangoda kuongororwa nguva dzose.

Reactive thrombocytosis (secondary thrombocytosis) haiwanzodi kurapwa. Kazhinji, mwero wemaplatelet unodzokera pakuva wakajairika kana mamiriro akakonzera kuwanda kwemaplatelet (senge kukuvara, hutachiona, kana reaction yekuvhiyiwa) apera. Zvisinei, kana uine zviratidzo, chiremba wako acharapa chikonzero chacho.

Kana uine Essential Thrombocythemia (ET) uye uine zviratidzo, chiremba wako anogona kukurudzira marapirwo akasiyana-siyana, akadai se:

• Kutora aspirin ine dose shoma zuva nezuva: Unogona kutora aspirin zuva nezuva kudzivirira kuvharika kweropa. Dose iyi yakaderera kazhinji haikonzeri kurwadziwa kwemudumbu kana kubuda ropa. Zvisinei, usatora aspirin nguva dzose usina kutaura nachiremba wako.
• Kutora mishonga inoderedza huwandu hwemaplatelet: Mishonga yakaita seHydroxyurea (mazita emhando: Droxia®, Hydrea®, Siklos®, Mylocel®) uye Anagrelide (zita remhando: Agrilyn®) inoderedza kugadzirwa kwemaplatelet mumongo wemapfupa. Interferon alfa (zita remhando: Multiferon®) inodzivirira maplatelet asina kujairika kuti asapatsanuke uye awedzere.
• Kuva nechirongwa chekubvisa maplatelet ako: Kana huwandu hwemaplatelet ako hwakakwira zvekuti uri panjodzi yekuve neropa rakagwamba rinogona kukuuraya, chiremba wako anogona kukurudzira chirongwa chinonzi plateletpheresis . Izvi zvinosanganisira kushandisa muchina kuchenesa maplatelet akawandisa kubva muropa rako. Zvisinei, muzviitiko zvakawanda zve thrombocytosis , plateletpheresis haidiwi.

Zvakakosha: Musatanga kana kumisa chero ipi zvayo yemishonga iyi musina kupiwa mazano nachiremba. Zvese zvinofanira kukurukurwa nachiremba wenyu uye kuitwa pasi pekutungamirirwa kwake.

Ko thrombocytosis inogona kurapwa zvizere here?

Kuongororwa kweEssential Thrombocythemia (ET)Parizvino hapana mushonga we thrombocytopenia. Zvisinei, chiremba wako anogona kukubatsira kugadzirisa dambudziko iri kuti aderedze njodzi yekugwamba kweropa. Kana paine reactive thrombocytosis (inokonzerwa nezvikonzero zvechipiri), huwandu hwemaplatelet hunowanzo dzokera kune zvakajairika kana chikonzero chacho charapwa.

Kubuda kweropa muropa kunogona kudzivirirwa here?

Matambudziko mazhinji anokonzera thrombocytosis haagone kudzivirirwa, kusanganisira Essential Thrombocythemia (ET) .

Kuputika kweropa kunotyisidzira hupenyu here?

Kuwanda kwemaplatelet mumuviri hakutyisidzi hupenyu, asi matambudziko anogona kuitika - akadai sekugwamba kweropa kana kubuda ropa zvakanyanya - anogona kuva nengozi.

Zvizhinji zvinokonzera thrombocytosis ndezvenguva pfupi, uye hazviwanzo kukonzera kuumbwa kweropa kwakanyanya. MuEssential Thrombocythemia (ET) , njodzi yacho yakakwira zvishoma. Zvisinei, chiremba wako achakutarisa zvakanyanya, onyora mishonga inodiwa, uye oita maitiro anodiwa kudzivirira kuumbwa kweropa kune njodzi. Saka usazvidya mwoyo.

Ndeipi tarisiro yemunhu ane thrombocytosis?

Reactive thrombocytosis inowanzopera kana dambudziko riripo rapapwa. Kunyangwe huwandu hwemaplatelet ako huchigona kukwira kwenguva pfupi (uye zvichida kwenguva refu mushure mekunge spleen yako yabviswa), secondary thrombocytosis kazhinji haikonzeri kuvharika kweropa zvisina kujairika.

Essential Thrombocythemia (ET) , kana kuti primary thrombocytosis, inogona kukonzera matambudziko ekubuda ropa zvakanyanya kana kuomesa ropa. Kutora mishonga yekuchengetedza huwandu hwemaplatelet ako hwakaenzana kunogona kubatsira kudzivirira izvi. Zvisinei, mushure memakore akawanda echirwere ichi, bone marrow fibrosis (mavanga emubofu) inogona kuitika. Vanhu vashoma vane Essential Thrombocythemia (ET) vanogonawo kurwara neleukemia .

Ndinofanira kuona chiremba wangu rini?

Tevedzera mirairo yachiremba wako zvakananga nezvekuti unofanira kuenda kunoongororwa nachiremba kangani uye kana uchifanira kuongororwa ropa kuti uone huwandu hwemaplatelet mumuviri wako.

Ndinofanira kuenda kuDhipatimendi reEmergency (ETU) riini?

Kana ukaona zviratidzo zvestroke kana chirwere chemwoyo, fonera 1990 nekukasika kana kuenda kuchipatara chiri pedyo newe. Ziva zviratidzo izvi.

Mibvunzo ipi yandinofanira kubvunza chiremba wangu?

Unogona kubvunza chiremba wako mibvunzo yakaita seiyi:

• Ndinofanira kunetseka here nezvehuwandu hwemaplatelet angu akakwira?
• Ndichafanira kuongororwazve kuti ndione mazinga emaplatelet angu zvakare here?
• Ndezvipi zviedzo zvandinofanira kuita kuti ndizive chikonzero cheThrombocytosis yangu?
• Ndeapi marapirwo amunokurudzira?
• Ndezvipi zvandingaite mumararamiro angu kuti ndigone kurarama nechirwere ichi?

Kana zvabuda muongororo yeropa rako zvikaratidza kuti maplatelet ako akakwira, usavhunduka. Maplatelet ako anogona kukwira nekuda kwezvikonzero zvakasiyana-siyana. Zvizhinji zvezvikonzero izvi hazvidi kurapwa. Asi kana huwandu hwako hwakakwira nguva dzose uye uine zviratidzo, chiremba wako achaedza kutsvaga chikonzero. Kunyatsotarisa uye kushandisa mishonga kunogona kudzivirira matambudziko akakomba ane chekuita ne thrombocytosis.

Pakupedzisira, zvinhu zvekurangarira (Mharidzo Yekuenda Kumba)

Zvakanaka, tataura zvakawanda nezveThrombocytosis nhasi, handiti? Ndinovimba wanzwisisa izvi zvakanaka.

Chinhu chinonyanya kukosha ndechekuti usatye kana ukaona kuti maplatelet ako akakwira. Haasi ese ma thrombocytosis ane njodzi.

• Reactive Thrombocytosis ndiyo inonyanya kuwanikwa, uye inowanzo kukonzerwa nechimwe chikonzero chenguva pfupi. Izvi zvinovandudzikawo kana chikonzero ichocho charapwa.
• Essential Thrombocythemia (ET) imhando isingawanzoitiki inogona kuda kurapwa kwenguva refu.
• Iva nechokwadi chekuongororwa kwakakodzera uye kurapwa sezvakarairwa nachiremba wako.
• Usaregeredza zviratidzo chero zvipi zvazvo. Tsvaga rubatsiro rwechiremba nekukasika, kunyanya kana uchibuda ropa zvisina kujairika, uine maronda, une musoro wakanyanya, une kurwadziwa muchipfuva, kana kuti uchinetseka kufema.
• Taura pachena nachiremba wako. Bvunza chero mibvunzo kana zvinokunetsa.

Yeuka kuti hausi wega. Nekutungamirirwa kwakakodzera kwechiremba nerutsigiro, unogona kurarama zvakanaka nechirwere ichi uye kurarama hupenyu hwakanaka.