Zvakajairika kunzwa kutya kana chiremba wako akakuudza iwe kana mwana wako kuti une dambudziko reitsvo, uye panguva imwe chete, iye akakuudza zita refu, rakaomarara sekuti `Complement 3 Glomerulopathy`. Izvi zvinonzi `C3G` muchidimbu. Ichi chirwere cheitsvo chisingawanzoitiki. Kunyangwe chirwere ichi chichinyanya kubata vana nevechidiki, chinogona kukura chero pazera ripi zvaro. Saka nhasi, ngatitaurei nezvechirwere ichi chinonzi C3G, sekunge tiri kutaura neshamwari, nenzira iri nyore.
Chii chinonzi C3G ichi?
Zvichitaurwa zviri nyore, C3G chirwere cheitsvo chinokonzerwa ne "complement system", iyo iri chikamu cheimmune system yemuviri wedu, isingashande nemazvo. Iyi complement system yakafanana nemapurisa anorwisa utachiona nemabhakitiriya anopinda mumuviri wedu. Zvisinei, mumunhu ane C3G, mashandiro esystem iyi anokanganiswa, uye inotanga kukuvadza itsvo dzake.
Kune mhando mbiri huru dzechirwere cheC3G:
1. Chirwere cheDense Deposit (DDD)
2. C3 Glomerulonephritis (C3 Glomerulonephritis - C3GN)
Mhando dzose dziri mbiri dzinogona kukonzerwa nezvikonzero zvemajini (zvichida zvenhaka) kana zvimwe zvinetso zvehutano zvinoitika muhupenyu.
Chii chinokonzera izvi? Chii chinoitika kuitsvo?
Funga nezveitsvo dzedu semafirita etii. Mafirita aya anonzi glomeruli . Aya ndiwo anosefa ropa redu, anorichenesa, uye anobvisa tsvina isingadiwe kuburikidza neweti.
Muchirwere cheC3G, kusashanda zvakanaka kwataurwa pamusoro apa mu complement system kunokuvadza mafirita aya akapfava anonzi glomeruli. Kana kukuvara uku kukaitika, maburi ari mufirita anokura, uye mapuroteni, pamwe nemasero matsvuku nemachena eropa, anofanira kunge ari muropa, anotanga kubuda muweti. Nekufamba kwenguva, kukuvara uku kunogona kuwedzera uye kutokonzera kutadza kushanda kweitsvo. Dzimwe ongororo dzinoratidza kuti DDD inobata vanhu vadiki pane C3GN.
Ndezvipi zviratidzo zvechirwere cheC3G?
Havasi vese vane C3G vachasangana nezviratidzo zvakafanana. Zvisinei, zvakakosha kuziva izvi. Ngatitarisei zviratidzo zvikuru.
| Chiratidzo | Tsananguro iri nyore |
|---|---|
| Mapuroteni muweti (Proteinuria) | Mapuroteni akawandisa muweti. Weti inogona kunge yakaita furo, ine makore, kana kuti yakasviba. Kana chirwere ichi chakanyanya (nephrotic syndrome), zvimwe zviratidzo zvakaita sekuzvimba zvinogonawo kuitika. |
| Ropa muweti (Hematuria) | Kukuvadzwa kwemafirita eitsvo kunoita kuti masero matsvuku eropa aungane muweti. Weti inogona kutsvuka, kutsvukuruka, kana kusviba. |
| Kuora kweganda | Nekuti itsvo hadzisi kushanda zvakanaka, mvura inoungana mumuviri, zvichikonzera kuzvimba mumakumbo, maoko, zvitsitsinho, uye kutenderedza maziso. |
| Kukwira Kweropa | Kuwedzera kwekumanikidzwa mutsinga dzeropa nekuda kwekusabviswa kwemvura zvakanaka kubva muitsvo. |
| Kuneta uye hope | Nekuti itsvo hadzisefe tsvina zvakanaka, dzinoungana muropa. Izvi zvinogona kukanganisa uropi uye kukonzera kuneta, hope, uye kuoma kutarisisa. Chirwere cheitsvo chinogonawo kukonzera anemia, izvo zvinogonawo kuwedzera kuneta. |
| Kutapukirwa Kunowanzoitika | Kusasimba kwesimba remuviri rekubatsira muviri kunoderedza kugona kwemuviri kurwisa utachiona, izvo zvinogona kukonzera kutapukirwa kakawanda. |
| Matambudziko Emaziso | Kutadza kuona zvakanaka kunogona kuitika nekuda kwehuwandu hwemapuroteni nemafuta (drusen) mu retina. |
| Kuisa mafuta muganda zvisina kurongeka (Acquired partial lipodystrophy) | Kuparadzwa kwemasero emafuta nehurongwa hwekuwedzera mafuta kunogona kukonzera kuti dzimwe nzvimbo dzemuviri dzitete, nepo dzimwe nzvimbo dzichigona kukura uye mafuta akawanda akachengetwa. |
Pamusoro pezvo, zviratidzo zvakaita sekusvotwa, kurutsa, kushaya chido chekudya, kushaya hope, ganda rakaoma uye rinokwenya, kuravira kwesimbi mumuromo, uye kukwenya kwetsandanyama husiku zvinogona kuitika mukutadza kushanda kweitsvo .
Unoona sei izvi, Chiremba?
Nzira chete yekuziva chirwere cheC3G ndeyekuongororwa kweitsvo . Izvi zvinosanganisira kutora chidimbu chidiki cheitsvo uchishandisa mushonga wekudzivirira kurwadziwa uye kuchiongorora uchishandisa maikorosikopu. Iyi ndiyo nzira chete yekuona kuti itsvo dzakakuvara zvakadii.
Pamusoro pezvo, chiremba wako anogona kukurudzira kuongororwa ropa neweti uye pamwe nekuongororwa kwemajini.
Chii chandinofanira kubvunza chiremba?
Panguva yakaita seiyi, ungave nemibvunzo yakawanda mupfungwa dzako. Kurukura zvinhu izvi zvakajeka nachiremba wako. Semuenzaniso:
- Ndakawana sei C3G?
- Ndine rudzii rweC3G? (DDD kana C3GN?)
- Ndedzipi nzira dzakanakisisa dzekutarisira hutano hwangu nechirwere ichi?
- Ndedzipi nzira dzekurapa dzandinadzo?
- Chii chandingatarisira mune ramangwana nechirwere ichi?
Ndezvipi zvinorapwa izvi?
Kutaura chokwadi, hapana mushonga mumwe chete unogona kurapa chirwere cheC3G zvachose parizvino. Zvisinei, kune nzira dzakasiyana siyana dzinogona kudzora chirwere ichi, kuderedza zviratidzo, uye kuderedza kukuvara kweitsvo.
- Dzora BP nekubuda kweprotein: Mishonga yekumanikidzwa kweropa (Angiotensin-converting enzyme (ACE) inhibitors uye Angiotensin II type-1 receptor blockers (ARBs)) inogona kuderedza kubuda kweprotein muweti uye kunonotsa kufambira mberi kwechirwere.
- Kudzora Cholesterol: Kana uine cholesterol yakakwira (hyperlipidemia), tsvakiridzo yakaratidza kuti mishonga inoderedza cholesterol inogona kubatsira kudzora kuipa kwechirwere cheC3G.
- Mishonga inodzvinyirira masoja emuviri: Musanganiswa wemishonga inodzvinyirira masoja emuviri, akadai seglucocorticoids ne mycophenolate mofetil (MMF), inogona kudzivirira kudzokera shure kwechirwere kune vamwe varwere.
- Kurapa kwemazuva ano: Mishonga inorwisa kenza yakaita se `eculizumab` inogona kudzora mashandiro emuviri wemushonga unosimbisa masero uye kunonoka kufambira mberi kwechirwere. Pamusoro pezvo, mushonga mutsva unonzi `iptacopan` uri kudzidzwa parizvino. Waratidza mhedzisiro yakanaka kwazvo, saka wakatenderwa kukurumidzisa tsvakiridzo pauri.
Ndinofanira kuzvitarisira sei?
Kungofanana nemishonga, maitiro aunozvitarisira nawo akakoshawo mukudzivirira chirwere ichi.
- Kudya kwakanaka: Idya michero yakawanda, miriwo, nyemba, uye zviyo zvakakwana. Deredza mafuta akawandisa, munyu, uye shuga. Chiremba wako anogona kukuudza kuti uderedze kudya kwako potassium, sodium (munyu), kana phosphate. Usambofa wakaita shanduko huru pakudya kwako usina kutanga wabvunza chiremba wako.
- Chengetedza hutano hwako: Kunyangwe uchinzwa zvakanaka, tora mishonga yako sezvakarairwa nachiremba wako. Udza chiremba wako nezvemimwe mishonga, mavhitamini, kana zvimwe zvinovaka muviri zvauri kutora.
- Kurovedza muviri: Kurovedza muviri kunogona kukubatsira kurara zvakanaka, kuwedzera simba rako, uye kuderedza njodzi yako yezvirwere zvemwoyo. Taura nachiremba wako nezvehurongwa hwekurovedza muviri hwakakunakira.
- Dzivisa kusvuta: Izvi zvakanaka kwazvo pahutano hwako hwese.
- Deredza doro: Taura nachiremba wako nezvekunwa doro uye tsvaga mazano.
Chii chatingatarisira mune ramangwana?
Kana wangoonekwa uine chirwere cheC3G, timu yako yezvekurapa ichakubatsira kuwana nzira yakanakisisa yekurapa.
Mune zvimwe zviitiko, chirwere ichi chinogona kutowedzera kuipa. Vanhu vanosvika 50% vane C3G vanowana chirwere cheitsvo chekupedzisira (ESRD) mukati memakore gumi mushure mekuonekwa kuti vane chirwere ichi. Panguva iyi, kugona kweitsvo kubvisa tsvina kunenge kwapera zvachose. Kuongororwa kwetsvo kana kuisirwa itsvo kunogona kudiwa.
Asi zvakakosha kuyeuka kuti kunyangwe mushure mekuisirwa itsvo, pane mukana mukuru wekuti chirwere cheC3G chichadzokazve muitsvo itsva. Saka taura nachiremba wako kwenguva yakareba nezvesarudzo yakanakira iwe.
Chikwata chenyu chekurapa chingasanganisira chiremba wezvirwere zvetsinga, chiremba weropa, uye chiremba wezvirwere. Zvakakosha kuchengetedza hukama hwakanaka navo.
Mharidzo Yekuenda Nayo Kumba
- C3G chirwere cheitsvo chisingawanzoitiki asi chakakomba chinokonzerwa nekusashanda zvakanaka kwemuviri, icho chiri chikamu chemuviri wemuviri.
- Zviratidzo zvikuru zvinogona kusanganisira mapuroteni kana ropa muweti, kuzvimba, BP yakakwira, uye kuneta.
- Chirwere ichi chinoonekwa ne biopsy yeitsvo.
- Kunyangwe pasina mushonga chaiwo weizvi, chirwere ichi chinogona kudzorwa uye itsvo dzinogona kudzivirirwa nekudzora BP, mishonga inodzora dziviriro yemuviri, uye mararamiro ane hutano.
- Zvakakosha kuti ugare uchitaurirana nechikwata chako chekurapa uye utevedzere mirairo yavo nemazvo.
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