Pamwe wakambonzwa izwi rekuti " cortisol , " kunyanya kana uchitaura nezve " stress ." Asi cortisol haisi "stress hormone" chete. Kutaura zvazviri, ihormone inokosha inoita basa rakakosha mumiviri yedu. Saka, nhasi, ngatitaurei nezve cortisol nenzira iri nyore yaunogona kunzwisisa.

Chii chinonzi cortisol? Inongova 'hormone yekushungurudzika' here?

Zvichitaurwa zviri nyore, cortisol ihormone inogadzirwa uye inoburitswa nema adrenal glands edu - ma glands maviri madiki ari pamusoro peitsvo. Imhando ye hormone inonzi glucocorticoid .

Ehe, sezvaungatarisira, cortisol yakabatana zvakanyanya nekushushikana. Kunyangwe tichisangana nekushushikana kwakanyanya , kushushikana kusingaperi , kana kushushikana kwakakomba, miviri yedu inoburitsa cortisol. Ndosaka ichinziwo "hormone yekushushikana."

Chii chinoita kuti cortisol ishande mumuviri wedu?

Cortisol ihormone inokanganisa nhengo dzese dzemuviri wedu uye inodzora mabasa akawanda akakosha. Ngationei kuti chii.

Kudzora maitiro aunoita kana wasangana nekushushikana

Paunonzwa njodzi kana kutya, muviri wako unobva watanga "kurwa kana kutiza," handiti? Panguva iyoyo, mahormone akaita seadrenaline anoburitswa. Zvadaro, kuti urambe wakangwarira, cortisol inotanga kuburitswa. Uyewo, cortisol inobatsira kuburitsa glucose , kana shuga, kubva muchiropa chedu kuti ipe simba rinodiwa panguva ino.

Metabolism uye huwandu hweshuga muropa

Kugayiwa kwemuviri (metabolism) inzira iyo miviri yedu inoshandisa simba kuti irarame, ishande, uye ishande. Cortisol inobatsira neizvi nekudzora mashandisiro anoita miviri yedu glucose sesimba.

Semuyenzaniso:

• Zvinokanganisa pancreas yedu, zvichideredza kugadzirwa kwe insulin uye zvichiwedzera kugadzirwa kwe glucagon. Kunyange hazvo insulin ichideredza shuga muropa, glucagon inowedzera huwandu hweshuga.
• Zvinokanganisawo mafuta, chiropa, uye tsandanyama mumuviri wedu, zvichidzora mashandisiro atinoita glucose.

Kudzvinyirira kuzvimba

Munguva pfupi, cortisol inogona kuwedzera dziviriro yemuviri wedu nekuderedza kuzvimba , uko kuri kuzvimba nekutsvuka mumuviri. Zvisinei, kana huwandu hwe cortisol hwakakwira nguva dzose, muviri wedu unogona kujaira. Zvadaro zvinopesana zvinoitika. Kuzvimba kunogona kuwedzera uye masoja emuviri anogona kushaya simba.

Kudzora BP

Hazvisati zvanyatsonzwisiswa kuti cortisol inodzora sei BP. Zvisinei, zvakaonekwa kuti mazinga e cortisol akakwira anogona kukonzera BP yakakwira, uye mazinga akaderera zvisingawanzoitiki anogona kukonzera BP yakaderera.

Inobatsira kudzora kurara nekumuka

Kazhinji, huwandu hwe cortisol hunenge hwakaderera patinorara husiku. Hunonyanya kukwira tisati tamuka mangwanani. Izvi zvinoratidza kuti cortisol ine simba guru pa circadian rhythm yedu, kana kuti sleep-wake cycle.

Miviri yedu inodzora sei mazinga e cortisol?

Muviri wedu une hurongwa hwakaoma kwazvo hwekudzora huwandu hwe cortisol. Mabasa makuru mune izvi anotambwa ne hypothalamus ne pituitary gland muuropi hwedu. Izvi zviviri zvinodzora kugadzirwa kwe cortisol ne adrenal glands.

Izvi ndizvo zvinoitika:

1. Kana huwandu hwe cortisol muropa mako hukadzikira, hypothalamus inoburitsa hormone inonzi CRH (corticotropin-releasing hormone) .
2. Homoni iyi yeCRH inoudza pituitary gland kuti igadzire homoni inonzi ACTH (adrenocorticotropic hormone) .
3. Homoni iyi yeACTH inozokurudzira ma adrenal glands kuti agadzire cortisol uye aibudise muropa.

Saka, kuti cortisol irambe iine hutano, nhengo dzese nhatu idzi—hypothalamus, pituitary gland, uye adrenal glands—dzinofanira kushanda nemazvo.

Chii chinoitika kana huwandu hwe cortisol hukawedzera?

Kana huwandu hwecortisol hwakakwira kwenguva yakareba, tinohudaidza kuti hypercortisolism . Izvi zvinowanzoitika nechirwere chinonzi Cushing's syndrome .

Ndezvipi zvikonzero zvekuwedzera kwecortisol mumuviri?

• Kushandisa kwenguva refu mishonga ye corticosteroid (semuenzaniso, prednisone, prednisolone, dexamethasone) muhuwandu hwakawanda.
• Matumbu anogadzira ACTH - Aya anowanzo buda mu pituitary gland.
• Ma cysts anoumbwa muma adrenal glands uye anogadzira cortisol yakawandisa.

Zviratidzo zve cortisol yakakwira

Kana huwandu hwe cortisol hwakakwira, kana kana uine Cushing's syndrome, unogona kuona zviratidzo zvakaita se:

• Kuwedzera huremu , kunyanya kumeso nedumbu.
• Mafuta anosara kumusana pakati pemafudzi (chigunwe chakafanana nebuffalo hump).
• Kuonekwa kwemavanga akafara, epepuru padumbu.
• Kushaya simba kwetsandanyama mumaoko ekumusoro nemumahudyu.
• Kuwedzera kwehuwandu hweshuga muropa , izvo zvinogona kukonzera chirwere cheshuga cherudzi rwechipiri.
• Kukwira kweropa .
• Kukura kwebvudzi kusingadiwe muvakadzi - chirwere chinonzi hirsutism .
• Kushaya simba kwemapfupa - Osteoporosis uye kutyoka kwemapfupa zvinogona kuitika.

Chii chinoitika kana huwandu hwe cortisol hukadzikira?

Kana huwandu hwe cortisol hwakaderera pane hwakajairwa, vanachiremba vanoti hypocortisolism , kana kuti adrenal insufficiency . Kune mhando mbiri huru dzeizvi.

Ndezvipi zvinokonzera kuderera kwecortisol mumuviri?

• Kusakwana kweadrenal gland: Izvi zvinowanzokonzerwa nemasoja edu ekudzivirira muviri achirwisa ma adrenal glands. Izvi zvinonziwo chirwere cheAddison .
• Kusakwana kweadrenal adrenal: Izvi zvinoitika kana pituitary gland isingashande zvakanaka ( hypopituitarism ) kana kana paine bundu repituitary.

Zviratidzo zve cortisol yakaderera

Kana mazinga e cortisol akaderera, unogona kuona zviratidzo zvakaita se:

• Kunzwa kuneta zvakanyanya (kuneta).
• Kuderedza uremu usingazive.
• Kushaya chido chekudya .
• Kuderera kweropa .

Ndingaitei kuti ndideredze huwandu hwe cortisol mumuviri?

Kana uine chirwere chakaita seCushing's syndrome, ungangoda kurapwa kuti uderedze huwandu hwe cortisol yako. Izvi zvinowanzosanganisira mishonga uye/kana kuvhiyiwa. Zvisinei, pane zvinhu zvishoma zvatinogona kuita kuti tibatsire kudzora huwandu hwe cortisol yedu:

• Rara zvakanaka: Matambudziko akadai sekushaya hope uye kushanda usiku zvinogona kuwedzera huwandu hwe cortisol.
• Kurovedza muviri: Kurovedza muviri nguva dzose kunovandudza kunaka kwekurara uye kunoderedza kushushikana.
• Dzidzira kufema zvakadzika: Kufema nenzira yakarongwa kunosimudzira sisitimu yedu yetsinga inodzikamisa muviri wedu uye inodzora "kuzorora nekugaya".
• Fara uye nyemwerera: Paunonyemwerera, mahormone anonzi endorphins anoburitswa uye huwandu hwecortisol hunodzikira.
• Ramba uine hukama hwakanaka nevanhu: Hukama hunogara huine matambudziko uye husina kugadzikana hunogona kukonzera kushushikana nguva dzose.